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Full-Text Articles in Biological Psychology
Analgesia Followed By Long-Term Hyperalgesia Generated By Disinhibition Of The Basolateral Amygdala, Derek Atchley
Analgesia Followed By Long-Term Hyperalgesia Generated By Disinhibition Of The Basolateral Amygdala, Derek Atchley
Wayne State University Theses
Stress produces bimodal effects on pain peception. During exposure to a stressor pain responses are inibited (i.e. stress-induced analgesia). However, following long-term exposure to a stressor increases in responsiveness to painful stimuli may develop (i.e. stress-induced hyperalgesia). Here I evaluated how a key component of the subcortical defense circuit and target of stress hormones contributes to the development of both stress-induced analgesia and hyperalgesia. Bicuculline methiodide, a GABAA antagonist, injected into the basolateral amygdala was used to mimic the neural effects of a stressor or threat exposure. Immediately following injection pain responsiveness was decreased as measured by vocalizations after discharge …
Sex Differences In The Dopaminergic Regulation Of Courtship, But Not Pairing Behaviors In Zebra Finches, Erin Marie Lowrey
Sex Differences In The Dopaminergic Regulation Of Courtship, But Not Pairing Behaviors In Zebra Finches, Erin Marie Lowrey
Wayne State University Theses
Dopamine is one of the key ingredients in the glue that cements social bonds in vertebrates. The D2 dopamine receptor has been implicated in the regulation of monogamous pair bonding in the prairie vole. While dopamine affects courtship behaviors in the male zebra finch, the behavioral role of dopamine acting at D2 receptors in both males and females deserves further attention. We hypothesized that the D2 receptor would regulate courtship and pairing behaviors in the male and female zebra finch. Sixteen males and females were tested using a repeated measures design. On day 1, the zebra finches were injected with …
The Contribution Of Genes And Hormones To The Sexual Differention Of The Zebra Finch Song System, Jessica Bayley Thompson
The Contribution Of Genes And Hormones To The Sexual Differention Of The Zebra Finch Song System, Jessica Bayley Thompson
Wayne State University Theses
Recent studies in the zebra finch suggest the sexual differentiation of the song system and singing behavior may not be solely driven by steroid hormones organizing the brain, and may be genetically driven. In fact, genes and hormones might act together to produce sexual differentiation of the brain. To test this hypothesis, animals were implanted with a 1mm pellet containing 50ug of 17b-estradiol or a blank pellet on the third day post-hatching. At post-hatch day 25, the brains were collected and a double label fluorescence in situ hybridization protocol using biotin and digoxigenin-tagged mRNA probes was used to simultaneously label …