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Articles 31 - 32 of 32
Full-Text Articles in Biological Psychology
Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker
Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker
Cal Poly Humboldt theses and projects
Caffeine has diverse effects on neurons including, potentially, protection against Parkinson’s-related neurodegeneration. Caffeine may protect neurons from damage by limiting mitochondrial membrane permeability through a calcium-dependent mechanism. This study was a first step investigating calcium’s role in caffeine neuroprotection in vivo using zebrafish larvae. Elavl3:GCaMP6s zebrafish, which express a genetically encoded fluorescent calcium indicator protein in most CNS neurons, received caffeine (0, 50, 125, 250 µM, bath applied) in an ascending dose series during fluorescence calcium imaging of a central catecholaminergic nucleus (a proposed zebrafish homolog of the locus coeruleus, a structure affected in Parkinson’s disease). Parallel experiments tested effects …
Restoration Of Attentional Deficits After Concussion, Katharine B. Earle
Restoration Of Attentional Deficits After Concussion, Katharine B. Earle
Cal Poly Humboldt theses and projects
Difficulties with concentration and attention are among the most prevalent symptoms experienced after concussion. Rest has been the most common form of recovery from concussion; however, new research is suggesting mild mental exertion to be an effective aid in recovery. Drawing from Attention Restoration Theory, this study evaluated the idea that cognitive engagement with natural environments can mitigate post-concussion directed-attention deficits. A between subjects repeated measures design was used to test directed-attention after video exposure to restorative/nature and nonrestorative/city environments. Measures of mood, connectedness to environment, and symptomology scores were also collected. No meaningful difference between exposure type was found …