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Articles 211 - 240 of 290
Full-Text Articles in Biological Psychology
An Animal Model Of The Motivational Symptoms Of Depression: Testing The Antidepressant Desipramine On An Effort-Related Choice Task, Samantha L. Collins
An Animal Model Of The Motivational Symptoms Of Depression: Testing The Antidepressant Desipramine On An Effort-Related Choice Task, Samantha L. Collins
Honors Scholar Theses
Patients with depression, schizophrenia, and other related disorders often show effort-related motivational symptoms such as anergia, psychomotor slowing, lassitude, and fatigue. Several studies have indicated that dopamine (DA) within the nucleus accumbens (NAc) is involved in the regulation of effort-related behavior. Interference with NAc DA alters response allocation in effort related choice procedures, biasing animals towards the alterative that can be obtained with minimal effort. Previous studies have shown that administration of the vesicular monoamine transporter-2 (VMAT-2) inhibitor tetrabenazine (TBZ) shifts behavior in rats responding on the FR5/chow choice procedure causing a decrease in lever pressing and a compensatory increase …
Using Otoacoustic Emissions To Evaluate Efferent Auditory Function In Humans, Simon Henin
Using Otoacoustic Emissions To Evaluate Efferent Auditory Function In Humans, Simon Henin
Dissertations, Theses, and Capstone Projects
The auditory system continually adapts to changes in the acoustic environment over short periods of time. This fine-tuning of its dynamics is mediated in part by the medial olivocochlear (MOC) bundle, a neural feedback loop which aids in the regulation of cochlear micro-mechanics. The ability to measure the response of the MOC system in humans may provide significant insight into unique cochlear functions, such as its sharp frequency selectivity and wide dynamic range. In humans the efferent system can be investigated non-invasively using otoacoustic emissions (OAEs). However, how OAEs can best be used to evaluate efferent function, the pitfalls associated …
A Pilot Study On The Effects Of Exercise On Depression Symptoms Using Levels Of Neurotransmitters And Eeg As Markers, Timothy H. Barclay, Scott Richards, James Schoffstall, Chad Magnuson, Christine Mcphee, Josh Price, Stephen Aita, Audrey Anderson, Dan Johnson, Jerry Price
A Pilot Study On The Effects Of Exercise On Depression Symptoms Using Levels Of Neurotransmitters And Eeg As Markers, Timothy H. Barclay, Scott Richards, James Schoffstall, Chad Magnuson, Christine Mcphee, Josh Price, Stephen Aita, Audrey Anderson, Dan Johnson, Jerry Price
Faculty Publications and Presentations
Context: The prescribing of exercise by physicians has become a popular practice, yet the effectiveness of exercise on symptoms of depression is difficult to determine due to a lack of randomized controlled trials with clinical populations. Reports also indicate that only a small percentage of physicians advise their patients regarding exercise and confusion still exists as to how much and what types are best. Aims: To understand the mechanisms that make exercise a viable treatment in depression. Settings and Design: This study employed a six‑week, two group, single‑level trial, pre‑ and posttest design using self‑report of symptoms, blood …
An Introduction To Drugs And The Neuroscience Of Behavior, Adam J. Prus
An Introduction To Drugs And The Neuroscience Of Behavior, Adam J. Prus
Books
This up-to-date text provides an introductory overview of the nervous system actions and behavioral effects of the major classes of psychoactive drugs, using pedagogy unique among pharmacology texts to make the topic approachable.
Grounded Labels From The Behavioral International Economic Development Growth Path Model On Economic Development Patterns From 2002-2012, Kenneth Thomas Davis
Grounded Labels From The Behavioral International Economic Development Growth Path Model On Economic Development Patterns From 2002-2012, Kenneth Thomas Davis
Walden Dissertations and Doctoral Studies
Economic models generally fail to adequately measure positive and negative growth paths in development through agrarian, industry, and service economies. The purpose of this grounded theory study was to design a new model that could accommodate both directions of growth and better measure development paths with particular attention to labors contributions. The theoretical foundation for this study was Walt Whitman Rostow's 5 economic stages of growth classifications. This Study attempted to find the most common economic growth path. While most development models use three to five classifications, this study used nine new classifications giving it a unique and specific look …
The Quetiapine Active Metabolite N-Desalkylquetiapine And The Neurotensin Nts1 Receptor Agonist Pd149163 Exhibit Antidepressant-Like Effects On Operant Responding In Male Rats, Todd M. Hillhouse, Zachary Shankland, Katelin S. Matazel, Ashley Keiser, Adam J. Prus
The Quetiapine Active Metabolite N-Desalkylquetiapine And The Neurotensin Nts1 Receptor Agonist Pd149163 Exhibit Antidepressant-Like Effects On Operant Responding In Male Rats, Todd M. Hillhouse, Zachary Shankland, Katelin S. Matazel, Ashley Keiser, Adam J. Prus
Journal Articles
Major depressive disorder (MDD) is the most common mood disorder in the United States and European Union; however, the limitations of clinically available antidepressant drugs have led researchers to pursue novel pharmacological treatments. Clinical studies have reported that monotherapy with the atypical antipsychotic drug quetiapine produces a rapid reduction in depressive symptoms that are apparent following one week of quetiapine treatment, and it is possible that the active metabolite N-Desalkylquetiapine, which structurally resembles an antidepressant drug, produces antidepressant effects. Neuropharmacological evaluations of the neurotensin NTS1 receptor agonist PD149163 are suggestive of antidepressant efficacy, but the effects of a NTS …
Sensory-Specific Appetition: Postingestive Detection Of Glucose Rapidly Promotes Continued Consumption Of A Recently Encountered Flavor, Kevin P. Myers, Marisa S. Taddeo, Emily K. Richards
Sensory-Specific Appetition: Postingestive Detection Of Glucose Rapidly Promotes Continued Consumption Of A Recently Encountered Flavor, Kevin P. Myers, Marisa S. Taddeo, Emily K. Richards
Faculty Journal Articles
It is generally thought that macronutrients stimulate intake when sensed in the mouth (e.g., sweet taste) but as food enters the GI tract its effects become inhibitory, triggering satiation processes leading to meal termination. Here we report experiments extending recent work (see [1]) showing that under some circumstances nutrients sensed in the gut produce a positive feedback effect, immediately promoting continued intake. In one experiment, rats with intragastric (IG) catheters were accustomed to consuming novel flavors in saccharin daily while receiving water infused IG (5 ml/15 min). The very first time glucose (16% w/w) was infused IG instead of water, …
Early Life Stress, Drug Abuse, Exercise Effects On Bdnf And Sex-Influenced Excercise Differences, Karissa Dold
Early Life Stress, Drug Abuse, Exercise Effects On Bdnf And Sex-Influenced Excercise Differences, Karissa Dold
Honors College Theses
In 2011, the U.S. reported 3 million child maltreatment cases, an uncomfortably high but recurring figure each year. Research shows exposure to early life stress (ELS) increases an individual’s susceptibility to substance abuse, specifically of nicotine, alcohol, and cocaine. Increased susceptibility may result from dysregulation of the HPA axis sustaining activation into adulthood after ELS. Hyperactivation of the HPA axis significantly reduces hippocampal BDNF, a neurotrophin involved in neuronal growth and plasticity. Reduced hippocampal BDNF may be a factor in substance abuse vulnerability. Additionally, research shows exercise protects hippocampal BDNF from stress induced down-regulation. To explore these relationships, this study …
The Effects Of Selected Drugs On The Memory Recall Of Sleep Deprived Mice, Jenn Pauldurai
The Effects Of Selected Drugs On The Memory Recall Of Sleep Deprived Mice, Jenn Pauldurai
Capstone Research Projects
Humans often make use of the neurotransmission altering effects of drugs such as caffeine, ephedrine, and ethanol. These drugs induce changes in memory and learning ability, specifically when used for sleep deprivation. English white mice (Mus musculus) have been shown to exhibit similar cognitive changes when administered drugs while sleep deprived. A sample of 20 mice was divided into three experimental groups (each group receiving a different drug) and one control group. Maze-testing demonstrated that mice performance decreased with sleep deprivation (Treatment-1) but all groups returned to baseline performance when injected (IP) with selected drugs (Treatment-2), regardless of …
The Effects Of Mindfulness Meditation On Rumination In Depressed People, Rachel A. Sluder
The Effects Of Mindfulness Meditation On Rumination In Depressed People, Rachel A. Sluder
Honors Theses and Capstones
Mindfulness meditation is a practice of focus, awareness, and non-judgmental acceptance of one's thoughts (Deyo et al., 2009; Kenny et al., 2007). Rumination is a maladaptive pattern of thought that is common in people with depression and other mood disorders. It can lead to further episodes of depression, and can be very destructive in that way (Nolen-Hoeksema, 2008). This paper reviews several studies on mindfulness meditation, depression, and rumination, with a focus on certain areas and phenomena such as alpha asymmetry (Keune et al 2013) and gamma band activity (Berkovich-Ohana et al., 2012). Modalities such as fMRI and EEG are …
Lateralized Difference In Tympanic Membrane Temperature: Emotion And Hemispheric Activity, Ruth E. Propper, Tad T. Brunyé
Lateralized Difference In Tympanic Membrane Temperature: Emotion And Hemispheric Activity, Ruth E. Propper, Tad T. Brunyé
Department of Psychology Faculty Scholarship and Creative Works
We review literature examining relationships between tympanic membrane temperature (TMT), affective/motivational orientation, and hemispheric activity. Lateralized differences in TMT might enable real-time monitoring of hemispheric activity in real-world conditions, and could serve as a corroborating marker of mental illnesses associated with specific affective dysregulation. We support the proposal that TMT holds potential for broadly indexing lateralized brain physiology during tasks demanding the processing and representation of emotional and/or motivational states, and for predicting trait-related affective/motivational orientations. The precise nature of the relationship between TMT and brain physiology, however, remains elusive. Indeed the limited extant research has sampled different participant populations …
Is Brain-Derived Neurotrophic Factor A Possible Mechanism Underlying Risperidone Sensitization In Adolescent Rats?, Qing Shu, Gang Hu, Ming Li
Is Brain-Derived Neurotrophic Factor A Possible Mechanism Underlying Risperidone Sensitization In Adolescent Rats?, Qing Shu, Gang Hu, Ming Li
Department of Psychology: Faculty Publications
Risperidone is one of the most widely used atypical antipsychotic drugs and is approved for the treatment of mental disorders (eg. schizophrenia, autism) in children and adolescents. The present study investigated the repeated treatment effect of risperidone and associated neurotropic mechanism in the phencyclidine (PCP)-induced hyperlocomotion model in adolescent rats. We examined whether repeated risperidone treatment would cause a sensitized inhibition of PCP-induced hyperlocomotion in adolescent rats, and whether such a sensitization effect was mediated by risperidone-induced alterations in Brain-Derived Neurotrophic Factor (BDNF), an important biomarker which plays a role in neuropathology of schizophrenia and action of antipsychotic medications. Male …
Childhood Rage: Diagnosis And Treatment Strategies For Severe Mood Dysregulation - Part 2: Diagnosis And Treatment, Gary A. Sibcy, John Kuhnley
Childhood Rage: Diagnosis And Treatment Strategies For Severe Mood Dysregulation - Part 2: Diagnosis And Treatment, Gary A. Sibcy, John Kuhnley
Faculty Publications and Presentations
No abstract provided.
Attachments And Neurobiology: Helping Children With Anxiety Disorders And Severe Mood Dysregulation, Gary A. Sibcy, John Kuhnley
Attachments And Neurobiology: Helping Children With Anxiety Disorders And Severe Mood Dysregulation, Gary A. Sibcy, John Kuhnley
Faculty Publications and Presentations
No abstract provided.
Treating Severely Depressed Adolescents With Integrated, Relational, Cognitive Therapy, Gary A. Sibcy
Treating Severely Depressed Adolescents With Integrated, Relational, Cognitive Therapy, Gary A. Sibcy
Faculty Publications and Presentations
No abstract provided.
Childhood Rage: Diagnosis And Treatment Strategies For Severe Mood Dysregulation - Part 1: Understanding Rage, Gary A. Sibcy, John Kuhnley
Childhood Rage: Diagnosis And Treatment Strategies For Severe Mood Dysregulation - Part 1: Understanding Rage, Gary A. Sibcy, John Kuhnley
Faculty Publications and Presentations
No abstract provided.
Traumatic Brain Injury: The Relationship Of Psychosocial Variables And Location Of Injury To Post-Injury Depression, Alicia L. Smith
Traumatic Brain Injury: The Relationship Of Psychosocial Variables And Location Of Injury To Post-Injury Depression, Alicia L. Smith
Theses, Dissertations and Capstones
Traumatic Brain Injury (TBI) affects nearly 1.4 million people in the United States annually, and of these, 10% to 77% will experience post-injury depression. Psychosocial variables such as previous substance and alcohol abuse, prior mental illness, low educational attainment, and poverty have been identified as possible risk factors. Additionally, the location of injury appears to play a key role particularly if the injury occurs in the left hemisphere. This study examined archival data from brain-injured patients in an effort to better understand the factors related to post-TBI depression. Past medical records of brain-injured adults (N = 52) were reviewed …
Adolescent And Adult Nicotine Exposure On The Acquisition Of Methamphetamine Self-Administration And The Reinstatement Of Extinguished Methamphetamine-Seeking In Male Rats, Joseph Allan Pipkin
Adolescent And Adult Nicotine Exposure On The Acquisition Of Methamphetamine Self-Administration And The Reinstatement Of Extinguished Methamphetamine-Seeking In Male Rats, Joseph Allan Pipkin
Theses Digitization Project
This study sought to determine the individual and combined contribution of adolescent and adult nicotine exposure on METH self-administration and METH-seeking behavior in male rats. Nicotine is a commonly abused substance among adolescents and is believed to be a "gateway" to other drugs of abuse. In support of the gateway hypothesis, cigarette smoking during adolescence is related to increased methamphetamine (METH) use in adulthood.
Preweanling Exposure To Selective Catecholamine Transporter Inhibitors Differentially Effects Morphine-Induced Antinociception In Adulthood, Joseph Marco Valentine
Preweanling Exposure To Selective Catecholamine Transporter Inhibitors Differentially Effects Morphine-Induced Antinociception In Adulthood, Joseph Marco Valentine
Theses Digitization Project
The purpose of this project is to determine how early methylphenidate exposure alters opioid receptor functioning in adulthood. To this end, we will administer selective monoamine transporter inhibitors for dopamine and norepinephrine (GBR-12904 and atomoxetine) during preweanling period and assess opioid function in adult rats by testing morphine-induced antinociception using the hot-plate and tail-flick tasks. In order to assess the effects of methylphenidate use on brain functions during development, investigations have been conducted in rats using ages roughly analogous to early and late childhood.
The Effect Of Visual Wulst Lesions And Trigeminal Nerve Sectioning On The Discrimination Of Magnetic Inclination In The Homing Pigeon (Columba Livia), Merissa Acerbi
Honors Projects
The ability of homing pigeons to return to their loft from unknown places has fascinated scientists for centuries. It is well established that homing pigeons, like migratory birds, posses an innate magnetic inclination compass to determine direction by measuring the angle between the magnetic field vector and the Earth's surface. Recent work has indicated that the avian magnetic compass is light mediated and appears to mediate magnetic information to the brain. This occurs via a visual pathway with processing in the visual Wulst area of the forebrain. There is, however, also evidence from other avian species that magnetic direction may …
Prenatal Stress, Depression, And Herpes Viral Titers, Pao-Chu Hsu
Prenatal Stress, Depression, And Herpes Viral Titers, Pao-Chu Hsu
USF Tampa Graduate Theses and Dissertations
Recent studies suggest that some cases of prenatal depression may be associated with reactivation of latent infections of the herpesvirus family. The possible relationships among stress, prenatal depression, and herpes viral reactivation in pregnancy are understudied and the molecular pathways such as the neuroimmune biogenic amine pathway are unidentified. Chronic stress shifts the T helper-1 cell (Th1) cytokine profile to a Th2 profile, which favors virus induced pathogenesis and survival. Pregnancy is also associated with a similar Th2 dominance. In non-pregnant individuals, exposure to psychological or physical stress may be associated with latent herpes viral reactivation and could result in …
Expression Of Borderline Personality Disorder Symptoms Across The Ovulatory Cycle: A Multilevel Investigation, Tory A. Eisenlohr-Moul
Expression Of Borderline Personality Disorder Symptoms Across The Ovulatory Cycle: A Multilevel Investigation, Tory A. Eisenlohr-Moul
Theses and Dissertations--Psychology
Borderline Personality Disorder (BPD) is a disabling condition characterized by chronic emotion dysregulation and behavioral impulsivity. Prospective studies that test proposed mechanisms of within-person change in BPD hold the key to improving symptom predictability and control in this disorder. A small body of evidence suggests that fluctuations in estradiol such as those occurring naturally at ovulation during the monthly female reproductive cycle may increase symptoms in women with BPD (DeSoto et al., 2003). Furthermore, there is preliminary evidence that both self-esteem and feelings of social rejection are highest at ovulation, when estradiol peaks (Durante and Hill, 2009; Eisenlohr-Moul et al., …
Placental Corticotropin-Releasing Hormone Mediates The Association Between Prenatal Social Support And Postpartum Depression, Jennifer Hahn-Holbrook, Christine Dunkel Schetter, Chander Arora, Calvin J. Hobel
Placental Corticotropin-Releasing Hormone Mediates The Association Between Prenatal Social Support And Postpartum Depression, Jennifer Hahn-Holbrook, Christine Dunkel Schetter, Chander Arora, Calvin J. Hobel
Psychology Faculty Articles and Research
Three decades of research point to both biological and psychological risk factors for postpartum depression, but very little research integrates the two. This study bridged this gap by testing whether prenatal social support predicted depressive symptoms at 8 weeks postpartum in a multiethnic sample of 210 women and whether the stress hormone placental corticotropinreleasing hormone (pCRH), measured at 19, 29, and 37 weeks’ gestation, mediated this relationship. We found that prenatal family support predicted significantly fewer depressive symptoms postpartum and more gradual increases in pCRH from 29 to 37 weeks’ gestation. Furthermore, steeper increases in pCRH during this same period …
Rats Acquire Stronger Preference For Flavors Consumed Towards The End Of A High-Fat Meal, Kevin P. Myers
Rats Acquire Stronger Preference For Flavors Consumed Towards The End Of A High-Fat Meal, Kevin P. Myers
Faculty Journal Articles
Rats learn to prefer flavors associated with postingestive effects of nutrients. The physiological signals underlying this postingestive reward are unknown. We have previously shown that rats readily learn to prefer a flavor that was consumed early in a multi-flavored meal when glucose is infused intragastrically (IG), suggesting rapid postingestive reward onset. The present experiments investigate the timing of postingestive fat reward, by providing distinctive flavors in the first and second halves of meals accompanied by IG fat infusion. Learning stronger preference for the earlier or later flavor would indicate when the rewarding postingestive effects are sensed. Rats consumed sweetened, calorically-dilute …
Autonomic And Behavioral Reactivity To An Acute Laboratory Stressor, Jeremy C. Peres
Autonomic And Behavioral Reactivity To An Acute Laboratory Stressor, Jeremy C. Peres
University of New Orleans Theses and Dissertations
Stress has been widely shown to directly influence people’s emotional and behavioral processing as well as their underlying biological systems. This project examined physiological and behavioral responses as indicators of stress and coping in the context of a psychosocial stressor in a controlled laboratory setting. We examined the association between indicators of behavioral coping and underlying physiological reactivity within participants while experiencing stress. Participants included 68 emerging adults. Physiological measures include autonomic biomarkers (e.g., heart-rate, skin conductance) at rest and during the stressor while behavioral indicators that were coded include acute verbal and non-verbal actions exhibited by participants during the …
Sex Differences In The Dopaminergic Regulation Of Courtship, But Not Pairing Behaviors In Zebra Finches, Erin Marie Lowrey
Sex Differences In The Dopaminergic Regulation Of Courtship, But Not Pairing Behaviors In Zebra Finches, Erin Marie Lowrey
Wayne State University Theses
Dopamine is one of the key ingredients in the glue that cements social bonds in vertebrates. The D2 dopamine receptor has been implicated in the regulation of monogamous pair bonding in the prairie vole. While dopamine affects courtship behaviors in the male zebra finch, the behavioral role of dopamine acting at D2 receptors in both males and females deserves further attention. We hypothesized that the D2 receptor would regulate courtship and pairing behaviors in the male and female zebra finch. Sixteen males and females were tested using a repeated measures design. On day 1, the zebra finches were injected with …
Middle School Teachers' Perceptions Of Barriers Of Managing Student Behavior, Winifred Nicole Whitlock
Middle School Teachers' Perceptions Of Barriers Of Managing Student Behavior, Winifred Nicole Whitlock
Walden Dissertations and Doctoral Studies
Despite training and support, many middle school teachers struggle to create, implement, and enforce research-based strategies to manage students' behaviors. The purpose of this case study was to examine teachers' perceptions about the barriers of managing student behavior. The research questions investigated 9 teachers' perceived barriers of managing student behavior at one middle school and the observed actions of these teachers' reactions to student behavior. Each participant was asked to participate in a 45-minute semistructured interview to examine their perceived barriers of managing student behavior and the strategies they use to manage student behavior relative to McGregor's theories X and …
Roles Of Internal Locus Of Control And Self-Efficacy On Managing Job Stressors And Ryff's Six Scales Of Psychological Well-Being, William A. Howatt
Roles Of Internal Locus Of Control And Self-Efficacy On Managing Job Stressors And Ryff's Six Scales Of Psychological Well-Being, William A. Howatt
Walden Dissertations and Doctoral Studies
The purpose of this study was to investigate the roles internal locus of control and self-efficacy play in moderating how employees manage their perceived work stress and positively engage in the behaviors that facilitate autonomy, environmental mastery, personal growth, self-acceptance, positive relations with others, and purpose in life. Investigators have documented the relationship between perceived workplace stress and strain and showed that how employees cope with perceived stress influences their psychological and physical health. However, there is less information available about the relationship between how employees cope with perceived workplace stress and engage in behaviors that facilitate their psychological well-being. …
Self-Hypnosis And Volitional Control Of Finger Temperature Among Adults, Joseph Swope
Self-Hypnosis And Volitional Control Of Finger Temperature Among Adults, Joseph Swope
Walden Dissertations and Doctoral Studies
Raynaud's disease is a condition in which circulation to the hands becomes restricted, causing an uncomfortable sense of cold and occasionally injury. The cause of Raynaud's disease is unknown. Earlier studies have shown that hetero-hypnosis is effective in the treatment of Raynaud's disease. Cost and access to providers limit such a treatment's availability. Theories of hypnosis suggest that self-hypnosis underlies all hypnotic processes. This study examined the utility of self-hypnosis and focused attention on the volitional control of hand temperature. Forty-three adult participants ranging in age from 19 to 77 years with no hypnosis experience were randomly divided into 2 …
The Relationship Between Depression And Cognitive Deterioration In Older Adults, Rakesh Chand
The Relationship Between Depression And Cognitive Deterioration In Older Adults, Rakesh Chand
Walden Dissertations and Doctoral Studies
The population structure of the United States is changing; the older age group is increasing in size relative to the younger generation. The trend is expected to continue, especially starting in 2020, when the baby boomer population---estimated at 80 million---will be reaching their 65 th birthday, a time associated with increasing health complications, including depression and dementia. The study employed a holistic paradigm as the conceptual framework to examine the association between depression and dementia in older adults, and generated a grounded theory to illuminate the relationship between depression and dementia. This theory was then used to assess the efficacy …