Biological Psychology Commons^™

Clinician Perspectives On Fistula Mental Health, Victoria K. Leonard

Doctoral Dissertations

Background – Obstetric fistula is a childbirth injury caused by prolonged labor that leads to stillbirth and incontinence, spurring social exclusion and isolation. These layers of trauma put women with fistula at great risk for psychological suffering, which has profound negative socioeconomic impacts on them, their families, and communities. This study captured treatment as usual at Comprehensive Community Based Rehabilitation in Tanzania (CCBRT), the country’s largest provider of fistula care.

Method – Improving holistic fistula treatment requires engaging the clinicians who care for women with fistula. This study aimed to investigate the training, beliefs, and treatment approaches of nurses and …

Towards A New Role Of Mitochondrial Hydrogen Peroxide In Synaptic Function, Cliyahnelle Z. Alexander

Student Theses and Dissertations

Aerobic metabolism is known to generate damaging ROS, particularly hydrogen peroxide. Reactive oxygen species (ROS) are highly reactive molecules containing oxygen that have the potential to cause damage to cells and tissues in the body. ROS are highly reactive atoms or molecules that rapidly interact with other molecules within a cell. Intracellular accumulation can result in oxidative damage, dysfunction, and cell death. Due to the limitations of H₂O₂ (hydrogen peroxide) detectors, other impacts of ROS exposure may have been missed. HyPer7, a genetically encoded sensor, measures hydrogen peroxide emissions precisely and sensitively, even at sublethal levels, during …

Examining The Effects Of Menstrual Cycle Phase And Hormonal Contraceptive Use On Women's Sleep, Charles Ethan Coombs

Psychological Science Undergraduate Honors Theses

Women overrepresent men for sub-optimal sleep, a consequence of hormone fluctuation in the menstrual cycle affecting sleep regulatory pathways. While research has examined the prevalence of sub-optimal sleep through cycle phases, little research has examined how hormonal contraceptives (HC’s) could similarly affect women’s sleep, while also neglecting to utilize subjective sleep measures. In this study, we examine subjective sleep quality among naturally cycling (NC) women, women using different HC types, and between active and inactive phase pill users by subjecting 463 women to a subjective sleep battery. We hypothesized that HC users would report more sub-optimal sleep than NC women. …

Cognitive Functioning In Well-Controlled Asthma, Erin Walsh

West Chester University Doctoral Projects

Asthma is a common lung disease that impacts lung functioning through inflammatory based mechanisms. Past research suggests that decreased blood oxygenation due to asthma attacks may impair cognitive capabilities (Irani et al., 2017). Moreover, the observed differences in cognition between those with and without asthma may be associated with disease severity or asthma control respectively in asthma populations. The current study explored differences in cognitive functioning between college students with and without self-reported asthma. Sociodemographic data, self-reported asthma severity, and measures of asthma control were collected. The current study did not find significant differences in measures of cognitive efficiency between …

Repeated Treatment With 5-Ht1a And 5-Ht1b Receptor Agonists: Evidence Of Tolerance And Behavioral Sensitization, Jordan Taylor

Electronic Theses, Projects, and Dissertations

Serotonin has been found to regulate several cognitive and physiological functions, and its role in depression and other neuropsychiatric disorders has been a focus of research. More specifically, a wealth of research regarding serotonin focuses on serotonergic medications in the treatment of neuropsychiatric disorders, such as depression and anxiety, and stimulates the 5-HT_1A and 5-HT_1B receptors. Within the last decade, there has been an increase in prescriptions of psychotropic medication for children, however, the efficacy and adverse effects of these drugs have not been evaluated in younger populations. While antidepressants reduce symptoms of depression in adults, they are …

Does A Single Night Of Mindfulness Meditation Improve Sleep And Stress In Female College Students?, Koushik Thudi

Psychological Science Undergraduate Honors Theses

Several recent studies have shown that mindfulness-based practices have been effective in treating sleep problems. However, these studies have primarily looked at multi-component interventions that take place over several weeks or months. No studies have evaluated the efficacy of short-term mindfulness-based practices on sleep the same night. This study aims to do just that. The sample consisted of 10 students attending the University of Arkansas. All participants slept in a sleep laboratory on two consecutive weekday nights. During one night, they completed a mindfulness-based exercise. The other night, they completed a similar control task (counterbalanced). Polysomnography-based sleep data were collected …

The Project That Claire, Uh I Mean The Student Completed: Relative Clauses And Repair Disfluencies, Claire O’Shaughnessy

Honors Theses

Several areas of psycholinguistics focus on the role of memory in language processing. Two of these areas are repair disfluencies and complex syntactic structures; however, these two topics have traditionally been investigated completely separately from one another. The current experiment combines these two topics by presenting listeners with spoken sentences containing subject-extracted relative clauses (SRCs) and object-extracted relative clauses (ORCs) in which the semantic similarity between the critical noun phrases (NPs) was manipulated. In addition, the sentences could be spoken fluently, or there could be a repair disfluency in which the reparandum contained information that would be potentially helpful in …

Working Memory During The Menstrual Cycle: A Study Of The Role Of The Different Phases Of The Menstrual Cycle On Working Memory, Daniella Brownrigg

Brescia Psychology Undergraduate Honours Theses

This study investigated the role of the menstrual cycle phases (Follicular, Luteal and Menstruation) on working memory components (verbal and visuospatial). Eighty-eight undergraduate students attending Brescia University college completed a survey regarding: demographics, menstrual cycle information and working memory cognitive tasks. The cognitive tasks were the Corsi Block Tapping Test and a shorter version of the Hooper Visual Organization test for visuospatial working memory; and the Forward Digit Span Test and the Semantic Verbal Fluency Subset: Animals from the Barcelona Test for verbal working memory. Participants were categorized into the different menstrual phases they were experiencing. No significant differences were …

Examining Allostatic Load As A Biological Mechanism Linking Childhood Adversity And Pediatric Pain, Angela Pascale

Theses and Dissertations

Despite a strong literature base relating childhood adversity to pain, the biological mechanisms underlying these associations remain unclear. Theoretical and preliminary empirical evidence supports allostatic load as a potential biological mechanism, though prior studies investigating associations between childhood adversity and elevated allostatic load and/or between elevated allostatic load and poorer pain outcomes have primarily focused on adult populations and individual allostatic load indicators rather than a comprehensive index. Thus, the current study built upon prior literature by testing longitudinal relationships between childhood adversity and multiple biological indicators spanning across physiological systems (i.e., comprehensive allostatic load index) and pediatric pain outcomes …

Systemic Growth Factor Increases As A Result Of Exercise May Reduce Alzheimer's Disease Risk In Midlife Mice And Humans, Amanda Hewes

Electronic Theses and Dissertations

Alzheimer’s disease (AD) is a neurodegenerative disorder with insidious onset and slow progression. AD research has traditionally been based on neuronal and glial dysfunction due to hallmark beta-amyloid and tau pathologies. Although literature supports an association between AD and cardiovascular disease and/or cardiovascular risk factors, vascular dysfunction as an etiology of AD has been overlooked. Cardiovascular risk factors have been associated with both cardiovascular and cerebrovascular disease in midlife individuals, an age at which modifiable risk factor management may be the most beneficial. Up to half of AD cases worldwide and in the USA are attributable to modifiable risk factors. …

The Psychotherapeutic Effects Of Consumer-Grade Eeg Neurofeedback On Mental Health And Well-Being, Madeline Slack

Electronic Thesis and Dissertation Repository

The current study assessed whether pairing mindfulness meditation with consumer-grade neurofeedback (using Muse) would be a feasible and satisfying (i.e., fulfillment and pleasure) intervention for mental health and well-being. This was assessed via a four-day mindfulness program where participants (N=34) were assigned to mindfulness with neurofeedback (n=17) or guided meditation (control; n=17) group. On each day of the program, participants engaged in two mindful sessions (five minutes each) in the morning and afternoon. Participants were administered a series of affective measures before and after the program, as well as throughout. Upon completion, participants were asked to rate …

Dietary Approaches To The Treatment Of Autism Spectrum Disorders, Dhira Patel

Loma Linda University Electronic Theses, Dissertations & Projects

This chapter reviews the literature surrounding autism spectrum disorders (ASD) and their relation to gastrointestinal (GI), behavioral, neurological, and immunological functioning. Individuals with ASDs often have poor GI health, including bowel motility issues, autoimmune and/or other adverse responses to certain foods, and lack of necessary nutrient absorption. These issues may be caused or exacerbated by restrictive behavioral patterns (e.g., preference for sweet and salty foods and/or refusal of healthy foods). Those individuals with GI issues tend to demonstrate more behavioral deficits (e.g., irritability, agitation, hyperactivity) and also tend to have an imbalance in overall gut microbiome composition, thus corroborating several …

Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley

LSU Doctoral Dissertations

Post-traumatic stress disorder (PTSD) is associated with elevated allostatic load, nearly double the risk for metabolic syndrome, reduced hippocampal volume, and contextual memory processing deficits. Emerging evidence suggests that these stress effects may predispose individuals to the development of PTSD, and there is a known relationship between chronic stress and metabolic dysfunction. In this work, we utilized two rat models of PTSD to explore these connections. We used an acute predator odor stressor to investigate the relationship between PTSD-like behaviors and mitochondrial dysfunction in the hippocampus of rats, and we observed that conditioned place avoidance was associated with reduced mitochondrial …

Black Hearts Matter: A Comparative Study Of Sociodemographic, Clinical, And Psychosocial Characteristics In Black And White Persons With Heart Failure, Hannah M Anderson Hughes

Theses and Dissertations

Heart failure (HF) is a chronic, progressive, debilitating illness that disproportionately affects Black individuals, often leading to poor quality of life (QOL). Various sociodemographic, clinical, and psychological characteristics are related to QOL in patients with HF. Because most studies do not include representative Black samples or report findings from racial subgroup analyses, these relationships and any existing racial differences are not well understood. The purpose of this descriptive, comparative study was to explore the relationships among sociodemographic, clinical, and psychological characteristics and QOL in patients with HF and to determine if there were racial differences between Black and White individuals. …

Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee

Pitzer Senior Theses

Children occasionally encounter dysregulation when interacting with their parents in relatively neutral or positive scenarios. Given that the cause of dysregulation is usually relational, meaning it is often cued by someone who is seen to have power or control over the person, children could be particularly susceptible to dysregulation in the presence of their parents. However, when examining the existing literature, there appeared to be a lack of research and knowledge concerning this topic, with much of the literature focusing on the effect of child stressors on parental dysregulation. As a result, the term parent-prompted dysregulation was developed to refer …

Sleep And Cardiovascular Reactivity To An Acute Virtual Stressor, Alaina Grace Tiani

Graduate Theses, Dissertations, and Problem Reports

Inappropriate response and magnitude of cardiovascular reactivity (CVR) to stress is a proposed mechanism through which environmental stressors are linked with poor cardiovascular health outcomes (Chida & Steptoe, 2010; Krantz & Manuck, 1984). Studies of reactivity to various laboratory tasks commonly control for factors known to influence CVR such as smoking, medication use, caffeine intake, and BMI; however, few have considered the influence of sleep on CVR. In order to determine whether sleep characteristics need to be assessed and considered in studies of CVR, this study aimed to examine the association between indices of sleep quality and the magnitude and …

Exploration Of Patient Variables And Characteristics Best Suited For Medical Marijuana Treatment For Anxiety And Depressive Disorders, Corey Gazoo

Dissertations

Individuals with posttraumatic stress, anxiety and depressive disorders are currently being prescribed medical marijuana as a treatment in many states across the United States. However, marijuana is still considered a schedule one narcotic by the Drug Enforcement Administration and federal government, which provides several barriers and challenges to conduct research such as approval from the U.S. Food and Drug Administration and following guidelines from the National Institute on Drug Abuse issued by the DEA. Additionally, individuals prescribed medical marijuana for mental health disorders are not always thoroughly instructed on the type of medical marijuana, the dosage, and how frequently to …

Medication Versus Brain-Based Treatment: Evaluation Treatment Preferences Of Parents Of Children With Adhd, Rebecca Recio-Swift

Electronic Theses and Dissertations

Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most prevalent neurodevelopmental disorders across the world. Currently, treatment for ADHD mostly consists of either medication or behavioral therapy or a combination of both. However, research has shown that medication used as therapy for the treatment of ADHD has side effects which parents deem undesirable for their children. Therefore, recent research has focused on patient and parent preferences. Studies have found that behavioral or other treatment options may often be chosen over medications. These same studies have documented the characteristics of parents that prefer certain treatments for their children. The purpose of this …

Predicting Inattentional Blindness With Pupillary Response In A Simulated Flight Task, Kellie D. Kennedy

Psychology Theses & Dissertations

Inattentional blindness (IB) is the failure of observers to notice the presence of a clearly viewable but unexpected visual event when attentional resources are diverted elsewhere. Knowing when an operator is unable to respond or detect an unexpected event may help improve safety during task performance. Unfortunately, it is difficult to predict when such failures might occur. The current study was a secondary data analysis of data collected in the Human and Autonomous Vehicle Systems Laboratory at NASA Langley Research Center. Specifically, 60 subjects (29 male, with normal or corrected-to-normal vision, mean age of 34.5 years (SD = 13.3) were …

Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, Leif Peterson

Master's Projects and Capstones

The Japanese health practice of Reiki attempts to maximize the latent ability of the human system to heal itself. The Reiki system, established over a century ago, combines multiple Asian health traditions, experimenting with practices that maximize the natural processes of the body to perform its own repairs. Reiki encourages healthy behaviors that balance the mind and body, return the human system to a lowered stress level, and allow for an optimal recovery state for the patient. This paper illustrates how this Japanese health-affirming method can be integrated and utilized within existing health and medical practices. An area that is …

Neuropsychological Implications Of Nocturnal Hypoxemia In Sickle Cell Disease, Sheena Ram

Theses and Dissertations

Neuropsychological impairments have been observed in both individuals with sleep-disordered breathing and in individuals with sickle cell disease (SCD), but there has been little research on the potential effect of sleep-disordered breathing on neuropsychological function in individuals with SCD. This study aims to examine the effect nocturnal oxygen desaturations have on neuropsychological functioning in individuals with sickle cell disease when compared to those with non-sickle anemia and healthy controls. Thirty-four participants with SCD, 18 non-sickle anemia controls (ACTL), and 29 healthy controls (CTL), ages 9 to 63 years, participating in an IRB-approved Children’s Hospital Los Angeles study of cerebral blood …

A Conceptual Proposal For The Epigenetically Causal Relationship Between Parental Ptsd And Inflammatory Disease In Post Hoc Offspring., Emma Griffith

Williams Honors College, Honors Research Projects

Could a combat veteran's horrific experiences in early-2000s Afghanistan have a direct, biological impact his now-adult daughter's risk of a heart attack later in her life? This concept would have been unapologetically mocked a mere twenty years ago, and it has only been in the past decade that the new field of epigenetics has revealed a distinct possibility for this event to actually take place—for parents' experiences to profoundly influence the biology of their children. The major objective of this research project is to argue for the legitimacy of this theoretical phenomenon by discussing the latest data regarding PTSD's interaction …

Relationships Between Adverse Childhood Experiences, Inflammation And Pain In Youth And Emerging Adults With Sickle Cell Disease, Angela Pascale

Theses and Dissertations

Sickle cell disease (SCD) is a prevalent genetic disorder involving red blood cells. SCD is a multisystem disease and is connected to various severe medical complications, including debilitating pain. Though pain and inflammation have been connected to adverse childhood experiences (ACEs) in other populations, no prior work has investigated ACEs within a SCD population. The current study examined the prevalence of ACEs as well as the association of ACEs, inflammation, and pain in a sample of youth and young adults with SCD. Utilizing the biopsychosocial model of pain, I examined individual and cumulative ACEs as possible factors relating to inflammation, …

Efficacy Of Creative Interventions In Virtual Reality, Matthew Thomas Richesin

Masters Theses

Engaging in creative activities is known to increase well-being by reducing levels of stress, anxiety, and improve life satisfaction. Interventions utilizing creative activities have proven to enhance therapeutic results in various mental disorders. Similarly, virtual reality has emerged as an effective method of decreasing negative aspects of mental disorders. While both creative interventions and virtual reality show promise in enhancing well-being, the efficacy of combining the two has not been explored. This study aimed to combine and compare 2-dimensional and 3-dimensional art-making on stress, anxiety, and mood in a non-clinical college student sample. To accomplish this, both physiological and self-report …

Student Beliefs About What Factors Influence Their Gpa, Emma R. Denelsbeck

Senior Honors Projects, 2020-current

There are many different factors that contribute to grade point averages (GPAs) in college. Students may attribute their academic performance and GPAs to any number of different variables such as stress levels, sleep quality and alcohol use. The current study investigated what students believed had an effect on their GPA, and if these differed based on concussion history. This study examined if students thought that concussions affected their GPA. Participants were University students who completed an online survey consisting of the Texas Evaluation of Concussion History (TECH), and the Depression, Anxiety, and Stress Scale (DASS-21). The results of a Mann-Whitney …

Yoga To Decrease The Stress Response: Gentle Yoga Encourages Faster Decline In Salivary Cortisol Concentrations Following Participation In Tsst, Tabetha Gaile Hopke

MSU Graduate Theses

Short-term, activation of the human stress response system is beneficial as it prepares the body to deal with stressors at hand (McEwen & Stellar, 1993). If this system is overactive or chronically active however, it can negatively impact health and longevity (Cohen, Janicki-Deverts, & Miller, 2007). According to a review conducted by Ross & Thomas (2010) implementation of a yoga practice has been shown to down-regulate the stress response system. The present study aimed to expand on current research involving yoga for stress reduction by exploring whether participation in gentle yoga could decrease the stress response more quickly than naturally …

Redefining Burnout: Exploring Common Conceptualizations And The Neurophysiology Of Chronic Stress To Establish An Integrated Allostatic Model, Danny A. Guzzi

Dissertations

Burnout is a widely researched stress-related phenomenon associated with numerous adverse outcomes for employees and organizations. Unfortunately, burnout is not well understood and research to this point has been flawed due to a lack of consensus on the definition, dimensionality, and context of the construct. Prevalent conceptualizations of burnout have been criticized for being arbitrarily developed without solid theoretical foundation and for failing to clearly distinguish burnout from depression or other work-related conditions such as compassion fatigue, secondary traumatization, and vicarious traumatization. The current project first examines relevant literature to identify commonalities among prevalent burnout conceptualizations. Then relevant stress research …

Relations Among Maternal And Paternal Behavior And Children's Stress Biology, S.K. Jiaming Lin, Stacey N. Doan, John Milton

Scripps Senior Theses

Parenting behavior has been shown to have a wide range of effects, influencing children’s psychological and biological stress outcomes. Most research focuses on maternal parenting behaviors, with few studies observing the effects of paternal behaviors or the influence of both parents on their children. In this study, the relationship between maternal and paternal parenting behaviors was examined in its association to predict children’s cortisol levels. Cultural differences in parenting styles was also observed. American (N=86) and Chinese (N=97) families participated in the study, with parents reporting their behaviors. Children’s cortisol was collected during a stressor task and correlational analysis was …

Dispositional Empathy And Autonomic Reactivity During A Comfort Interaction, Alaina G. Tiani

Graduate Theses, Dissertations, and Problem Reports

The purpose of the current study was to examine the association between dispositional (trait) empathy and autonomic reactivity during dyadic interactions among women enrolled in undergraduate psychology courses. The primary research question was: do individuals who are deemed higher in dispositional empathy according to self-report exhibit differential autonomic reactivity patterns during a task in which they are asked to comfort another student experiencing emotional distress than those who are deemed lower in dispositional empathy? The literature on this relation has been mixed and has utilized photos or videos to evoke emotion; thus this study sought to examine the relation between …

The Effects Of Oral Contraceptives On Mood And Affect: A Meta-Analysis, Erica M. Motter

Cal Poly Humboldt theses and projects

Combined oral contraceptive (COC) pills are widely used by women of reproductive age, but there is still little conclusive evidence that exists about the mood-related side effects associated with their use. This meta-analysis examined the relationship between oral contraceptive use and mood effects such as depression and anxiety to determine what role, if any, that COCs may have in the worsening or improvement of women’s mood when taking them. Effect sizes compared the differences in women’s mood scores before taking COCs and after one or more cycles of use. Seventeen studies made up of 25 individual samples contributed 71 effect …