Biological Psychology Commons^™

Effects Of Social Interaction On Morphine Conditioned Place Preference In Adolescent Male Rats, Virginia G. Weiss

Theses and Dissertations--Psychology

The fact that adolescents commonly initiate drug use in social settings is well established. Both clinical and preclinical research has investigated how social interaction is altered by a variety of drugs of abuse. What is less understood is how the rewarding value of drugs of abuse is affected by the presence of social peers. This dissertation aimed to investigate the interaction of morphine and social play on conditioned place preference (CPP) in adolescent male Sprague Dawley rats, using both behavioral and immunohistochemistry (IHC) methods. Rats were exposed to morphine (0, 1, or 3 mg/kg; s.c.), social interaction, or a combination …

Investigating The Roles Of Mechanoreceptive Channels In Tactile Apparent Motion Perception: A Vibrotactile Study, Phill Kim, Philip Servos Dr.

Theses and Dissertations (Comprehensive)

Tactile apparent motion (TAM) is a perceptual phenomenon in which consecutive presentation of multiple tactile stimuli creates an illusion of motion. Employing a novel tactile display device, the Latero, allowed us to investigate this. The current study focused on the Rapidly Adapting (RA) channel and Slowly Adapting I (SAI) channel on the index finger. The experiment implemented vibrotactile masking stimuli to target the mechanoreceptive channels with the goal of gaining better insight into the involvement of mechanoreceptive channels in the perception of TAM. Masking stimuli were used because previous studies have used them to differentiate between different channels; a …

Neurocorrelates Of The Mirror Neuron System In Children With Chromosome 22q11.2 Deletion Syndrome, Ade Marais

LSU New Orleans Theses and Dissertations

Activation of brain regions that make up the mirror neuron system (MNS) is thought to reflect processing and perceiving behavior, action, and intentionality of other organisms. Sensing and perceiving motor behavior in others is an important component of understanding and participating in social interactions. Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) are diagnosed with serious medical, cognitive, and socio-emotional symptoms. Atypical development and function of the MNS may underpin some aspects of socio-emotional impairment and autism spectrum disorder (ASD)-like symptomology reported. This study of the MNS investigates differences in activation in the operculum, sensorimotor areas, and basal ganglia (BG) in …

Volition And Action In The Human Brain: Processes, Pathologies, And Reasons, Itzhak Fried, Patrick Haggard, Biyu J. He, Aaron Schurger

Psychology Faculty Articles and Research

Humans seem to decide for themselves what to do, and when to do it. This distinctive capacity may emerge from an ability, shared with other animals, to make decisions for action that are related to future goals, or at least free from the constraints of immediate environmental inputs. Studying such volitional acts proves a major challenge for neuroscience. This review highlights key mechanisms in the generation of voluntary, as opposed to stimulus-driven actions, and highlights three issues. The first part focuses on the apparent spontaneity of voluntary action. The second part focuses on one of the most distinctive, but elusive, …

The Effect Of Text Color And Text Grouping On Attention And Short Term Recall Memory, Emily Haynes

Honors College Research

This study sought to discover whether there was a connection between the attentional draw of a word, as represented by text color and grouping, and the likelihood of it being transferred into short term recall memory. College students at Harding University in Searcy, Arkansas were given one of six timed memory test scenarios and asked to recreate the list to the best of their ability. The students were then asked to complete a series of post-test questions designed to measure their perception of their own performance on the test. The students were also asked to complete a demographics questionnaire that …

Entrainment Of Voluntary Movement To Undetected Auditory Regularities, Aaron Schurger, Nathan Faivre, Leila Cammoun, Bianca Trovó, Olaf Blanke

Psychology Faculty Articles and Research

In physics “entrainment” refers to the synchronization of two coupled oscillators with similar fundamental frequencies. In behavioral science, entrainment refers to the tendency of humans to synchronize their movements with rhythmic stimuli. Here, we asked whether human subjects performing a tapping task would entrain their tapping to an undetected auditory rhythm surreptitiously introduced in the guise of ambient background noise in the room. Subjects performed two different tasks, one in which they tapped their finger at a steady rate of their own choosing and one in which they performed a single abrupt finger tap on each trial after a delay …

Roles Of Gabab, Muscarinic And Nicotinic Receptor Signaling In The Acquisition And Expression Of Fructose And Fat-Conditioned Flavor Preferences And Acquisition Of Quinine-Conditioned Flavor Avoidances In Rats, Francis M. Rotella

Dissertations, Theses, and Capstone Projects

In addition to increased intake of sweet solutions by mammals, learning, particularly classically-conditioned “Pavlovian-like” learning, also plays an important role. An orosensory conditioned flavor preference (CFP) can be elicited by pairing one novel flavor (conditioned stimulus, CS+) with a fructose solution and a second novel flavor (CS-) with a saccharin solution. Rats will prefer the CS+ flavor in a subsequent 2-bottle choice test with both flavors mixed in saccharin. Previous pharmacological analyses revealed that systemic administration of dopamine (DA) D1 and D2 as well as NMDA, but not opioid, receptor antagonists eliminated the acquisition (learning) of fructose-CFP. Further, expression of …

Designing An Authentic Behavioral Research Experience In The Classroom Using Siamese Fighting Fish, Betta Splendens, Gianne Souza, Ronald M. Coleman

STAR Program Research Presentations

Recently there have been major shifts in biology education towards emphasizing the teaching of the scientific process to more closely reflect actual scientific practices. Authentic research experiences require the development of many higher order cognitive skills. Creating an authentic research experience that appropriately scaffolds the development of these complex skills while engaging individual student motivation remains challenging in classroom settings. Some common challenges include limited time available for working with large numbers of students, cramped working areas, and limited funding and materials resources. Using the Siamese Fighting Fish, Betta splendens, we have created an economically viable authentic animal behavioral …

Sleep Deprivation And Voluntary Alcohol Consumption In Adult Rats, Charles M. Cowan Ii

Masters Theses, 2010-2019

Alcohol is a psychoactive drug with a large userbase among adults across the globe. However, alcohol use also reduces the quality of sleep in the user. Historically, research has focused on the effects of alcohol on sleep architecture, but recent research has started to examine the effects of sleep deprivation on alcohol consumption. This research examines the effects of sleep deprivation on voluntary alcohol consumption in adult rats. Twelve Sprague Dawley rats were given ad libitum access to food, alcohol (7% solution), and water for the duration of this study. Subjects were then placed into non-moving forced exercise wheels to …

Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier

Dissertations

Alcohol abuse is the third largest risk factor for disease world, responsible for an estimated 3.3 million deaths each year. The concomitant ingestion of alcohol and caffeine is hypothesized to increase risk factors associated with alcohol use alone by reducing subjective effects of intoxication. The zebrafish (Danio rerio) has recently garnered attention from researchers as an effective pre-clinical in-vivo animal model in behavioral pharmacology research, largely due to small size, low-cost and ease of drug delivery. A number of studies have reported the effects of alcohol and caffeine on zebrafish behavior at a variety of doses. However, the …

Cannabis Use Frequency And Mood On Creativity, Caitlin Clark

Cal Poly Humboldt theses and projects

This study examines the relationship between cannabis use (infrequent, moderate, and heavy use) and one’s mood (neutral, positive, and negative) on creativity. Folk ideas of creativity and the relationships between cannabis use and mood may not reflect the real relationship between these factors (e.g. regarding cannabis use, it is perceived to be linked with higher rates of creativity; regarding mood, negative states [i.e. tortured artist] are thought to fuel creativity). Although both cannabis use and mood have been found to influence creativity independently, the current study is unique in its aims to identify whether cannabis use and mood interact to …

Habitat Use By Bottlenose Dolphins, Tursiops Truncatus, In Roanoke Sound, North Carolina, Shauna Marisa Mcbride

Dissertations

Information on the habitat use of a species is important to develop conservation efforts and management strategies for that species. Roanoke Sound, North Carolina is primarily a seasonal habitat for bottlenose dolphins, Tursiops truncatus, from late spring to early fall, but little information is known about how dolphins use this area. Transect survey data and opportunistic survey data collected by the Outer Banks Center for Dolphin Research from 2009 to 2015 were used to analyze dolphin habitat use. The objectives of this project were to: 1) identify areas that were important to dolphins, 2) determine which behaviors were observed …

Observational Assessment Of Empathy In Parent-Child Verbal Exchanges And Their Influence On Child Behavior, Patty Carambot

Dissertations, Theses, and Capstone Projects

Empathy, the ability to both experientially share in and understand others’ thoughts, behaviors, and feelings, is vital for human adaptation. Deficits in empathy development have implications across the lifespan for the development of prosocial behavior, social functioning, mental health disorders, and risk for antisocial behavior (e.g., Guajardo, Snyder, & Petersen, 2009; Moreno, Klute & Robinson, 2008). In light of these societal and individual burdens, it is imperative to foster and strengthen the development of this ability early in life to prevent or ameliorate such negative outcomes. This type of prevention can take a variety of forms, but parent and child …

Ptsd From Childhood Trauma As A Precursor To Attachment Issues, Christy Owen

Fidei et Veritatis: The Liberty University Journal of Graduate Research

The past 20 years have been turbulent regarding Reactive Attachment Disorder (RAD), with conflicting research about its causes, effects, treatment, and prognosis. The current diagnostic criteria in the DSM-5 fails to adequately address this disorder. A number of deviant and maladaptive behaviors common amongst children with RAD are not even mentioned in the diagnostic criteria. As such, the diagnostic definition is almost unidentifiable or incompatible with real-life conduct manifestations of the disorder. Rather, this author contends that RAD is foundationally a unique and extreme form of Posttraumatic Stress Disorder (PTSD) from Early Childhood Trauma. The child endured unspeakable neglect and/or …

The Effects Of Lipopolysaccharide-Induced Neuroinflammation On Learning And Forgetting In Juvenile Rats, Michele Barry

Seton Hall University Dissertations and Theses (ETDs)

The inability to remember events experienced very early in life is referred to as Infantile Amnesia (IA) and has been observed in both humans and animals. Over the years interest in the phenomenon waned, but has recently increased with the discovery of new neurobiological methods to study brain function (e.g., Callaghan, Li & Richardson, 2014). The neurobiological mechanism behind IA has yet to be determined, but several innovative theories have been developed with these new research methods. The neurogenesis hypothesis theorizes that increased neurogenesis during early development disrupts previously established memories. The hippocampus, an area that mediates both the memory …

Evaluation Of The Discriminable Stimulus Effects Of 0.3 Mg/Kg 3, 4‑Methylenedioxypyrovalerone (Mdpv) And 1.0 Mg/Kg 4-Methylmethcathinone (4-Mmc) Using A Drug Discrimination Procedure In Male Sprague-Dawley Rats, Michael Berquist

Research and Creative Activities Poster Day

Experimental investigations into the behavioral and neurochemical effects of illicit β-ketophenethylamines (synthetic cathinones, “bath salts”) has increased in recent years. Two cathinone derivatives in particular, MDPV and mephedrone (4-MMC), have received a considerable amount of research attention given their relative popularity among users at the turn of the 21st century. Researchers investigating MDPV and 4-MMC have devoted much of their attention toward evaluating the drugs’ reinforcing efficacy, rewarding effects, receptor binding profiles, and effects on ambulatory responses.

There exist few published studies that have evaluated the discriminable stimulus effects of MDPV and 4-MMC using rodent drug discrimination procedures. To date, …

Previous Exposure To Lsd Fails To Enhance The Psychomotor Stimulant Effects Of D-Amphetamine In Male Sprague-Dawley Rats, Keli Herr

Research and Creative Activities Poster Day

• The hallucinogenic effects of lysergic acid diethylamide (LSD) have been largely attributed to its high affinity for 5-HT2A receptors. However, LSD also has a high affinity at several other monoamine receptors (Nichols, 2004; Passie et al., 2008).
• The contribution of dopaminergic mechanisms to LSD’s behavioral effects have not been investigated to the same extent that serotonergic mechanism have been studied. Some authors have hypothesized that chronic treatment of rats with LSD may produce a persistent behavioral state characterized by sensitivity to dopamine agonists (Marona-Lewicka and Nichols, 2007).
• Repeated exposure to psychostimulant drugs is known to produce progressive increases in locomotor …

The Effects Of Chronic Partial Sleep Deprivation On Alcohol Consumption And Delta Fos B Accumulation, Kristian Ponder

Showcase of Graduate Student Scholarship and Creative Activities

The present study explores the relation between sleep restriction and alcohol use and the neural substrates that result from chronic behaviors, such as transcription factors. Transcription factor activity is suggested as a possible outcome of chronic behaviors, such as addiction. Sleep is discussed as possible mediating factor in the relationship between specific transcription factors and alcohol. Analysis will focus on brain areas related to both sleep and reward.

Human Vision Inspires Cortisol And Immune Behaviors, J. Forrest Olsen

Departmental Honors Projects

Ten-minute slideshows of disease stimuli were presented to human participants who donated saliva samples before and after its completion. Much to our surprise, this research found cortisol decreased upon the visual perception of a disease threat, a response depicting the physiological consequences of Behavior Immune System activation. Even subliminal exposure to disease stimuli, totaling only 0.5 seconds over the ten-minute slideshow, was found to elicit a cortisol response.

Cognitive Phenotypes And The Evolution Of Animal Decisions, Tamra C. Mendelson, Courtney L. Fitzpatrick, Mark E. Hauber, Charles H. Pence, Rafael L. Rodríguez, Rebecca J. Safran, Caitlin A. Stern, Jeffrey R. Stevens

Faculty Publications

Despite the clear fitness consequences of animal decisions, the science of animal decision making in evolutionary biology is underdeveloped compared with decision science in human psychology. Specifically, the field lacks a conceptual framework that defines and describes the relevant components of a decision, leading to imprecise language and concepts. The ‘judgment and decision-making’ (JDM) framework in human psychology is a powerful tool for framing and understanding human decisions, and we apply it here to components of animal decisions, which we refer to as ‘cognitive phenotypes’. We distinguish multiple cognitive phenotypes in the context of a JDM framework and highlight empirical …

Acute And Chronic Effects Of Inhalants In Intracranial Self-Stimulation, Matthew Tracy

Theses and Dissertations

Inhalants are a loosely defined diverse group of volatile substances which people abuse. Despite widespread misuse of inhalants, there are limited preclinical methods available to study the reinforcement-like properties of inhalants. One procedure which has demonstrated substantial promise as a tool to investigate inhalant pharmacology is the intracranial self-stimulation (ICSS) procedure. ICSS utilizes pulses of electrical stimulation to the mesolimbic reward pathway to serve as a temporally defined and controlled operant reinforcer with a highly adjustable efficacy. The first aim of the project was to characterize the effects of commonly abused inhalants: including toluene, trichloroethane, nitrous oxide, isoflurane and R134a …

Slam Poetry: An Online Intervention For Treating Depression, Spencer J. Ruchti, Mercedes Becker, Cara Mckee, Austin Herron, Alex Swalling

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Given that depression is the “leading cause of disability worldwide,” and that less than 50% of people suffering from depression receive treatment, this study aims to provide support for a globally accessible depression treatment (WHO, 2012). The study conducted implemented an internet-based treatment for depression in which users were provided an opportunity to watch slam poetry videos related to mental health issues and write free responses regarding the content of the videos and their subjective experience of depression. Numerous studies provide support for the effectiveness of expressive writing, online mental health interventions, and slam poetry in particular for reducing symptoms …

Devaluation As A Strategy To Address Behaviourally Whether Fish Feel, Robert Ian Bowers

Animal Sentience

Failures of behavioural studies to address the question of whether fish feel pain have left scientists arguing on the basis of other criteria, including anatomy. I draw an analogy with a debate concerning the breadth of stimulus-response learning among nonhuman animals and propose an experiment that harks back to one solution to that debate: the devaluation paradigm. By changing the value of a noxious stimulus after training, one can differentiate a directly evoked response from a response to an intermediate representation, the pain.

Effects Of Repeated Quetiapine Treatment On Conditioned Avoidance Responding In Rats, Jun Gao, Min Feng, Natashia Swalve, Collin Davis, Nan Sui, Ming Li

Department of Psychology: Faculty Publications

The present study characterized the behavioral mechanisms of avoidance–disruptive effect of quetiapine in the conditioned avoidance response test under two behavioral testing (2 warning signals vs. 1 warning signal) and two drug administration conditions (subcutaneous vs. intravenous). In Experiments 1 and 2, well-trained adult male Sprague-Dawley rats were tested under the subcutaneous (s.c.) quetiapine treatment (5.0, 15.0, 25.0, 50.0 mg/kg) for 7 days in a novel procedure consisting of two conditioned stimuli (CS) (white noise serving as CS1 and pure tone as CS2). Only the highest dose (50.0 mg/kg) produced a persistent suppression of the avoidance response without impairing the …

Olfactory Enrichment In California Sea Lions (Zalophus Californianus), Mystera M. Samuelson

Dissertations

In the wild, California sea lions (Zalophus californianus) are exposed to a wide array of sensory information at all times. However, it is impossible for captive environments to provide this level of complexity. Therefore unique procedures and practices are necessary for the maintenance of physiological and psychological health in captive animals (Wells, 2009). This project aims to explore the behavioral effect of scent added to the environment, with the goal of improving the welfare of captive sea lions by introducing two scent types: 1.) Natural scents, found in their native environment, and 2.) Non-natural scents, not found in …

Differential Effects Of Methylenedioxypyrovalerone (Mdpv) And Mephedrone In Rats Trained To Discriminate Mdma Or A D-Amphetamine+Mdma Mixture, Eric Louis Harvey

Masters Theses

Recent reports on the abuse of novel synthetic cathinone derivatives call attention to serious public health risks of these substances. In response to this concern, a growing body of preclinical research has characterized the psychopharmacology of these substances, particularly mephedrone (MEPH) or methylenedioxypyrovalerone (MDPV), noting their similarities to MDMA and cocaine. The present study employed drug discrimination methodology to assess the discriminative stimulus effects of MEPH and MDPV in male Sprague-Dawley rats trained to discriminate 1.5 mg/kg 3,4 methylenedioxymethamphetamine (MDMA) or a mixture of 1.5 mg/kg MDMA and 0.5 mg/kg d-amphetamine (MDMA+AMPH). After establishing dose response functions with each training …

Effects Of Altering Motivation In Pigeons Performing A Titrating-Delayed-Matching-To-Sample Task, Zachary J. Zimmermann

Masters Theses

In order to better understand the role motivating operations (MOs) serve in preceding and evoking behavior, it is useful to examine the effects of whether manipulating motivation can influence performance on tasks with known behavioral outcomes. It is well established that altered stimulus control is responsible for changes in responding on tasks of generalization and discrimination. Therefore, if stimulus control could be influenced by MOs, then perhaps stimulus discriminations could be improved by manipulating the relevant MO. To this end, the effects of altering motivation via food deprivation were examined in pigeons using a titrating-delayed-matching-to-sample task. Additional pharmacological variables (i.e., …

Paradoxical Interaction Between Ocular Activity, Perception, And Decision Confidence At The Threshold Of Vision, Aaron Schurger

Psychology Faculty Articles and Research

In humans and some other species perceptual decision-making is complemented by the ability to make confidence judgements about the certainty of sensory evidence. While both forms of decision process have been studied empirically, the precise relationship between them remains poorly understood. We performed an experiment that combined a perceptual decision-making task (identifying the category of a faint visual stimulus) with a confidence-judgement task (wagering on the accuracy of each perceptual decision). The visual stimulation paradigm required steady fixation, so we used eye-tracking to control for stray eye movements. Our data analyses revealed an unexpected and counterintuitive interaction between the steadiness …

Effects Of 17Β-Estradiol On Learning And Memory And Strategy Use During A Hole Board Spatial Navigation Task In Aged Male Rats, Megan Berthiaume

Seton Hall University Dissertations and Theses (ETDs)

Treatment with 17β- estradiol has been shown to ameliorate age related deficits in spatial learning and memory as well as to promote the use of an allocentric strategy during spatial navigation. While the majority of research using 17β- estradiol has been done using females rodents, there have been studies showing an improvement in spatial learning and memory and promoted use of allocentric strategies in spatial navigation in males as well. In males testosterone (T) is metabolized into estradiol by aromatase. As circulating levels of T decline with aging there is less available T to be metabolized into estradiol. The current …

Repeated Effects Of The Neurotensin Receptor Agonist Pd149163 In Three Animal Tests Of Antipsychotic Activity: Assessing For Tolerance And Cross-Tolerance To Clozapine, Shinnyi Chou, Collin Davis, Sean Jones, Ming Li

Department of Psychology: Faculty Publications

Neurotensin is an endogenous neuropeptide closely associated with the mesolimbic dopaminergic system and shown to possess antipsychotic-like effects. In particular, acute neurotensin receptor activation can inhibit conditioned avoidance response (CAR), attenuate phencyclidine (PCP)-induced prepulse inhibition (PPI) disruptions, and reverse PCP-induced hyperlocomotion. However, few studies have examined the long term effects of repeated neurotensin receptor activation and results are inconsistent. Since clinical administration of antipsychotic therapy often requires a prolonged treatment schedule, here we assessed the effects of repeated activation of neurotensin receptors using an NTS1 receptor selective agonist, PD149163, in 3 behavioral tests of antipsychotic activity. We also investigated whether …