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Biological Psychology Commons

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Clinical Psychology

Western Michigan University

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Full-Text Articles in Biological Psychology

Assessment N>E Discriminative Stimulus Effects Of (±)-3,4-Methylenedioxymethamphetamine (Mdma, "Ecstasy") And (+Lysergic Add Diethylamide (Lsd) In A Three-Lever Drug Discrimination Procedure, Amy K. Goodwin Jun 2002

Assessment N>E Discriminative Stimulus Effects Of (±)-3,4-Methylenedioxymethamphetamine (Mdma, "Ecstasy") And (+Lysergic Add Diethylamide (Lsd) In A Three-Lever Drug Discrimination Procedure, Amy K. Goodwin

Dissertations

(±)3,4-Methylenedioxymethamphetamine (MDMA) is a common drug of abuse known as "ecstasy." Currently, MDMA is classified into the traditional drug classes as both a "stimulant" and a "hallucinogen" because it is reported to share both subjective and physiological properties of both classes. MDMA is thought to produce its psychoactive effects by acting as both a serotonin and a dopamine agonist. However, the relative importance of the serotonin and dopamine neurotransmitter systems in mediating the stimulus properties of MDMA remains unclear.

The drug discrimination assay is used to classify drugs as "similar" or "dissimilar," as well as to examine underlying neurochemical changes …