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Full-Text Articles in Psychology

"I Shall Not Fear:" Secure Attachment To G-D As A Buffer Against Anxiety, Peryl Agishtein Feb 2015

"I Shall Not Fear:" Secure Attachment To G-D As A Buffer Against Anxiety, Peryl Agishtein

Dissertations, Theses, and Capstone Projects

Religion has a long and mixed history in the field of psychology. Historically, some leading figures in the field viewed religion as a source of neuroses and poor mental health; others saw a more positive spiritual resource. Recently, empirical data on religion and mental health has proliferated. There is now consensus that religion is associated with lower depression. However, the link between religion and anxiety is less clear-cut. This paper proposes that a) religion can have exacerbating or alleviating effects on anxiety depending on which aspect of religion is being studied and b) the primary religious variable that affects anxiety …


The Effects Of Stress And Burden On Caregivers Of Individuals With A Chronic Illness, Betty Wilborn-Lee Jan 2015

The Effects Of Stress And Burden On Caregivers Of Individuals With A Chronic Illness, Betty Wilborn-Lee

Walden Dissertations and Doctoral Studies

Informal caregivers have played a significant social and economic role in the care and treatment of individuals diagnosed with chronic illness. However, caregiving can have harmful effects on a caregiver's physical, psychological, and emotional well-being. Using caregiver stress theory as the theoretical framework, the purpose of this archival research was to determine the predictive relationship of stress in relation to caregiver quality of life for 309 selected cases. Correlational and hierarchical multiple linear regression analyses were used to examine the relationship between the independent variables and the dependent variable. The independent variables examined were environment and context, stressors related to …


Cortisol Levels And Voltage Conditions Of College Students, Adriana Steffens Jan 2015

Cortisol Levels And Voltage Conditions Of College Students, Adriana Steffens

Walden Dissertations and Doctoral Studies

There is a limited research base on low voltage brain conditions, which are characterized by electrical activity being measured at below 20 microvolts. The purpose of this study was to examine the relationship between saliva cortisol levels and voltage using an EGG in a college student population. Illuminating this relationship is important to inform how low voltage conditions can affect daily memory and cognitive functioning of undergraduate college students that may be a result of stress. The college student population may be vulnerable to the low voltage condition because of stress from the transition between teenage and adult life and …


Psychophysiological Markers Of Cognitive Reactions To Depictions Of Corporal Punishment, Hope Reuschel Jan 2015

Psychophysiological Markers Of Cognitive Reactions To Depictions Of Corporal Punishment, Hope Reuschel

Online Theses and Dissertations

The following study assessed cognitive mechanisms, via physiological measures, in reaction to photos depicting conditions of corporal punishment, nonphysical punishment, and a neutral control. Detections in skin conductance (SCR) were used to examine autonomic stress response. The current study examined executive working memory (WM) processes as influenced by cognitive and psychophysiological response to viewing depictions of various punishments being implemented. Results of this study found that while participants reacted differently, autonomically and cognitively, to photo conditions, these differences were unrelated to other anticipated moderators such as tendency to internalize shame or greater personal exposure to corporal punishment. Subsequent analyses, however, …


Identification Of Resilient Individuals And Those At Risk For Performance Deficits Under Stress., Brent D. Winslow, Meredith B. Carroll, Jonathan W. Martin, Glenn Surpris, George L. Chadderdon Jan 2015

Identification Of Resilient Individuals And Those At Risk For Performance Deficits Under Stress., Brent D. Winslow, Meredith B. Carroll, Jonathan W. Martin, Glenn Surpris, George L. Chadderdon

Aeronautics Faculty Publications

Human task performance is affected by exposure to physiological and psychological stress. The ability to measure the physiological response to stressors and correlate that to task performance could be used to identify resilient individuals or those at risk for stress-related performance decrements. Accomplishing this prior to performance under severe stress or the development of clinical stress disorders could facilitate focused preparation such as tailoring training to individual needs. Here we measure the effects of stress on physiological response and performance through behavior, physiological sensors, and subjective ratings, and identify which individuals are at risk for stress-related performance decrements. Participants performed …


Does Self-Care Moderate The Relation Of Stress To Quality Of Life Of Female Doctoral Students In Professional Psychology?, Erin Elizabeth Ayala Jan 2015

Does Self-Care Moderate The Relation Of Stress To Quality Of Life Of Female Doctoral Students In Professional Psychology?, Erin Elizabeth Ayala

Legacy Theses & Dissertations (2009 - 2024)

Increasing numbers of women are pursuing doctoral degrees in psychology, and the stress of being a female doctoral student can create a risk for aversive consequences (e.g., ineffective clinical work, impaired competence). Psychologists lack an understanding of the extent to which women can protect themselves from undue stress in professional psychology programs by engaging in self-care. The lack of a comprehensive framework for this phenomenon calls for the need to apply and test the Health Promotion Model to the experience of women in professional psychology programs. The current investigation assessed the extent to which self-care activities would moderate the negative …


Burnout-Depression Overlap: A Review, Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent Jan 2015

Burnout-Depression Overlap: A Review, Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent

Publications and Research

Whether burnout is a form of depression or a distinct phenomenon is an object of controversy. The aim of the present article was to provide an up-to-date review of the literature dedicated to the question of burnout–depression overlap. A systematic literature search was carried out in PubMed, PsycINFO, and IngentaConnect. A total of 92 studies were identified as informing the issue of burnout–depression overlap. The current state of the art suggests that the distinction between burnout and depression is conceptually fragile. It is notably unclear how the state of burnout (i.e., the end stage …


Meaning In Life And Self-Efficacy's Relationship To Depression, Anxiety, And Stress: A Study Of Coastal Residents Affected By The Gulf Oil Spill, Brandy Baczwaski Jan 2015

Meaning In Life And Self-Efficacy's Relationship To Depression, Anxiety, And Stress: A Study Of Coastal Residents Affected By The Gulf Oil Spill, Brandy Baczwaski

Electronic Theses and Dissertations

On April 20, 2010, the Deepwater Horizon Oil Platform exploded, killing 11 people and spilling approximately 210 million gallons of oil into the Gulf of Mexico over the following months. Disasters such as the Gulf Oil Spill affect individuals in many ways, including the possible onset of psychological issues such as depression, anxiety, and stress. Because mental health effects are comfollowing a disaster, it is important to understand potential protective factors that may decrease the risk of negative consequences related to disaster events. The presence and severity of psychological distress, as well as the method of coping, varies between individuals …


12-Item Depression, Anxiety, And Stress Scales (Dass-12): Associations With Self-Report Measures, A Semi-Strcutured Interview, And Behavioral Tasks, Eu Gene Chin Jan 2015

12-Item Depression, Anxiety, And Stress Scales (Dass-12): Associations With Self-Report Measures, A Semi-Strcutured Interview, And Behavioral Tasks, Eu Gene Chin

Electronic Theses and Dissertations

To date, only one study has examined the psychometric properties of the 12-item depression, anxiety, and stress scales (DASS). Moreover, all psychometric studies conducted with the DASS-21 have focused narrowly on associations with semi-structured interviews and other relevant self-report measures. In order to address these limitations, I proposed to diversify the ways in which we examine the DASS instrument (for both the 12- and 21-item versions). First, I examined the extent to which the DASS instrument is able to predict responses to behavioral tasks and whether the DASS was able to produce hypothesized convergent and divergent relationships with relevant self-report …


Temperament And Child Maltreatment: A Closer Look At The Interactions Among Mother And Child Temperament, Stress And Coping, Emotional And Behavioral Regulation, And Child Maltreatment Potential, Amanda Lowell Jan 2015

Temperament And Child Maltreatment: A Closer Look At The Interactions Among Mother And Child Temperament, Stress And Coping, Emotional And Behavioral Regulation, And Child Maltreatment Potential, Amanda Lowell

Electronic Theses and Dissertations

Several theoretical risk models were proposed previously regarding the prediction of child maltreatment. Although child maltreatment was predicted individually in these models by such variables as parent temperament, emotional and behavioral regulation, stress, coping, and child temperament, these variables were not yet examined collectively. As such, a new transactional theory was proposed for the current study. As part of this study, a national community sample of 158 culturally diverse mothers of young children who were between the ages of 1½- to 5-years rated their own temperament, emotional and behavioral regulation abilities, parenting stress, daily hassles, and coping behaviors as well …


Stability And Change: Stress Responses And The Shaping Of Behavioral Phenotypes Over The Life Span, Michael B. Hennessy, Sylvia Kaiser, Tobias Tiedtke, Norbert Sachser Jan 2015

Stability And Change: Stress Responses And The Shaping Of Behavioral Phenotypes Over The Life Span, Michael B. Hennessy, Sylvia Kaiser, Tobias Tiedtke, Norbert Sachser

Psychology Faculty Publications

In mammals, maternal signals conveyed via influences on hypothalamic-pituitary-adrenal (HPA) activity may shape behavior of the young to be better adapted for prevailing environmental conditions. However, the mother's influence extends beyond classic stress response systems. In guinea pigs, several hours (h) of separation from the mother activates not only the HPA axis, but also the innate immune system, which effects immediate behavioral change, as well as modifies behavioral responsiveness in the future. Moreover, the presence of the mother potently suppresses the behavioral consequences of this innate immune activation. These findings raise the possibility that long-term adaptive behavioral change can be …


The Impact Of Baby Sign Training On Stress Levels Of Daycare Providers, Grisel Julieta Rodriguez Jan 2015

The Impact Of Baby Sign Training On Stress Levels Of Daycare Providers, Grisel Julieta Rodriguez

Open Access Theses & Dissertations

Proponents of baby sign claim improvements in child-caregiver interactions and reductions in parental stress as benefits of implementing baby sign. Due to research contradicting the claims, and to the rise in daycare attendance, the current study investigated the effects of a baby sign workshop on the stress perception of daycare providers. A pre-test post-test between groups design with 20 participants was conducted using the Perceived Stress Scale (PSS10) and a workshop-specific descriptive survey as measures. The difference between the post-test stress levels of experimental and control groups approached significance, as did the differences between pre-test and post-test results for the …


A Mindfulness-Based Stress Reduction Psychoeducational Program In Postpartum Support Groups, Marina Pesserl Jan 2015

A Mindfulness-Based Stress Reduction Psychoeducational Program In Postpartum Support Groups, Marina Pesserl

Walden Dissertations and Doctoral Studies

Postpartum Depression (PPD) affects 15% of women after childbirth. Its etiology includes psychoneuroimmunologic factors with long-lasting postpartum stressors that lead to allostatic overload. Using mindfulness-based stress reduction (MBSR) for PPD has not yet been studied. Addressing this literature gap, the potential benefits of including an 8-week MBSR component based on Beck's theory of PPD at support groups were examined in this phenomenological study based on a sample of 10 women and 2 group facilitators. Purposes of the study included describing the experience of PPD and the MBSR program, identifying the stage of behavioral change of the participants, and describing the …


Understanding The Impact Os Stress, Irrational Health Beliefs, And Health Behaviors Among Adults18-45, Toni Loe Rabalais Jan 2015

Understanding The Impact Os Stress, Irrational Health Beliefs, And Health Behaviors Among Adults18-45, Toni Loe Rabalais

Walden Dissertations and Doctoral Studies

This study examined the role of stress on irrational health beliefs and health behaviors among individuals 18-45 years old. Previous research has shown that this age group reported higher stress levels, more physical symptoms of stress, and the highest level of negative health behaviors. The theoretical frameworks were health belief model, the transactional model of stress and coping theory, and Ellis's concept of irrational beliefs. A survey using 3 published instruments measured the perceived stress level, irrational health beliefs, and health behaviors of a sample of 97 individuals aged 18-45. The data were quantitatively assessed using a mediation model to …


Effects Of Mild To Moderate Stress On Mental Rotation, James Frederick Bell Jan 2015

Effects Of Mild To Moderate Stress On Mental Rotation, James Frederick Bell

Walden Dissertations and Doctoral Studies

Mental rotation (MR) is the ability to mentally shift one's visual perspective of any object by changing the orientation of a mental image of that object. Research into the effects of stress on MR could be used to help improve understanding of a variety of visual-spatial tasks performed in hyper-vigilance situations. However, until the present study, there has been no research on the effects of stress on MR. The Yerkes-Dodson Law predicts performance will be improved when an individual is exposed to mild to moderate stress. The purpose of this study was to answer three research questions. The questions examined …


The Correlation Among Personality Characteristics, Stress, And Coping Of Caregivers Of Individuals With Intellectual And Developmental Disabilities, Natasha O'Connor Jan 2015

The Correlation Among Personality Characteristics, Stress, And Coping Of Caregivers Of Individuals With Intellectual And Developmental Disabilities, Natasha O'Connor

Walden Dissertations and Doctoral Studies

There is little research on the coping strategies of direct support professional caregivers working with the intellectually disabled (ID) and developmentally disabled (DD). The study was guided by Lazarus and Folkman's (1984) theory of the transactional model of stress and coping. The purpose of this study was to assess whether there is a correlation among the independent variables of coping and personality characteristics with stress as the dependent variable. A convenience sample of 69 professional caregivers was used. Data were collected using the Ways of Coping Questionnaire, Perceived Stress Scale, NEO-FFI-3, and a demographic questionnaire. A correlational analysis was conducted …


Stress And Coping In Women Of Color, Elizabeth Ochoa, Marya Shegog Jan 2015

Stress And Coping In Women Of Color, Elizabeth Ochoa, Marya Shegog

McNair Poster Presentations

  • Stress and coping research has identified stress and lack of coping mechanisms as contributors to the onset of chronic disease, as well as contributing to a low quality of life among women of color in comparison to their Caucasian counterparts (Mays, Yancey, Cochran, Weber, & Felding, 2002; Andrews, Felton, Wewers, & Heath, 2004).
  • The research examining health disparities in African American women, a subset of women of color, have found that African American women do not have the effective skills to cope with stress, which may contribute to the onset of disease (Donovan & West, 2014; Woods- Giscombé, 2010; Mullings, …


Five Facets Of Mindfulness And Psychological Health: Evaluating A Psychological Model Of The Mechanisms Of Mindfulness, David B. Brown, Adrian J. Bravo, Corey R. Roos, Matthew R. Pearson Jan 2015

Five Facets Of Mindfulness And Psychological Health: Evaluating A Psychological Model Of The Mechanisms Of Mindfulness, David B. Brown, Adrian J. Bravo, Corey R. Roos, Matthew R. Pearson

Psychology Faculty Publications

There has been an increasing focus on determining the psychological mechanisms underlying the broad effects of mindfulness on psychological health. Mindfulness has been posited to be related to the construct of reperceiving or decentering, defined as a shift in perspective associated with decreased attachment to one's thoughts and emotions. Decentering is proposed to be a meta-mechanism that mobilizes four psychological mechanisms (cognitive flexibility, values clarification, self-regulation, and exposure), which in turn are associated with positive health outcomes. Despite preliminary support for this model, extant studies testing this model have not examined distinct facets of mindfulness. The present study used a …


Parenting Behaviors Of Sleepy Parents: Associations With Emotion Regulation And Stress, Lauren R. Gilbert Jan 2015

Parenting Behaviors Of Sleepy Parents: Associations With Emotion Regulation And Stress, Lauren R. Gilbert

Theses and Dissertations--Psychology

Over the last decade, the topic of sleep has garnered a great deal of interest from psychologists, due to the physiological, emotional, and behavioral outcomes associated with its deprivation. However, questions remain to be answered regarding sleep's influence in the day-to-day life of families. The current study examines the importance of sleep deprivation for parents’ parenting behaviors during problem solving discussions with their children; emotion regulation and stress reactivity are examined as mediators of these associations. Participants were 196 families with a child between the ages of 6-11. Parents filled out diaries for 7 days prior to their in-lab visit, …


Antecedents Of Adolescents' Hope: Personality, Parental Attachment, And Stressful Life Events, Kristin L. Otis Jan 2015

Antecedents Of Adolescents' Hope: Personality, Parental Attachment, And Stressful Life Events, Kristin L. Otis

Theses and Dissertations

In the past decade, psychology has concentrated on the importance of identifying psychological qualities in individuals that indicate positive mental health and flourishing. Hope has been proposed to be one of these qualities (Day, Hanson, Maltby, Proctor, & Wood, 2010; Marques, & Lopez, 2014). This study examined the relations among parental attachment, stressful life events, personality variables, and hope in a sample of 647 middle school students from one middle school in a Southeastern US state. The results showed statistically significant correlations between hope and all four predictor variables as well as students’ grade levels and socioeconomic status (SES). The …


Profiles Of African American College Students’ Risky Behaviors: General And Culturally-Specific Stress And Social Support As Factors Of Risk And Resilience?, Isha Walwina Metzger Jan 2015

Profiles Of African American College Students’ Risky Behaviors: General And Culturally-Specific Stress And Social Support As Factors Of Risk And Resilience?, Isha Walwina Metzger

Theses and Dissertations

Studies show that, while alcohol use and risky sexual activities increase during emerging adulthood, college students are more likely to engage in these behaviors than their non-student counterparts (Slutske et al., 2004). Researchers should explore risk behavior participation among African American youth, as they often face health disparities and more severe consequences of engaging in these acts than their White American counterparts (Sharma & Atri, 2006; Jackson, Hodge, & Vaughn, 2010). Although epidemiological and variable-centered studies often examine the drinking and sexual behavior of African American college students, there is a need for research utilizing a profile-oriented approach to explore …


Developmental Stress, Condition, And Birdsong: A Case Study In Song Sparrows., Kim L Schmidt, Elizabeth A Macdougall-Shackleton, Shawn P Kubli, Scott A Macdougall-Shackleton Oct 2014

Developmental Stress, Condition, And Birdsong: A Case Study In Song Sparrows., Kim L Schmidt, Elizabeth A Macdougall-Shackleton, Shawn P Kubli, Scott A Macdougall-Shackleton

Brain and Mind Institute Researchers' Publications

Sexual-selection theory posits that ornaments and displays can reflect a signaler's condition, which in turn is affected both by recent and developmental conditions. Moreover, developmental conditions can induce correlations between sexually selected and other traits if both types of traits exhibit developmental phenotypic plasticity in response to stressors. Thus, sexually selected traits may reflect recent and/or developmental characteristics of signalers. Here, we review data on the relationships between birdsong, a sexually selected trait, and developmental and current condition of birds from a long-term study of a population of song sparrows (Melospiza melodia). Field studies of free-living birds indicate that the …


Examining The Associations Of Racism, Sexism, And Stressful Life Events On Psychological Distress Among African-American Women, Danelle Stevens-Watkins, Brea Perry, Erin L. Pullen, Jennifer Jewell, Carrie B. Oser Oct 2014

Examining The Associations Of Racism, Sexism, And Stressful Life Events On Psychological Distress Among African-American Women, Danelle Stevens-Watkins, Brea Perry, Erin L. Pullen, Jennifer Jewell, Carrie B. Oser

Educational, School, and Counseling Psychology Faculty Publications

African-American women may be susceptible to stressful events and adverse health outcomes as a result of their distinct social location at the intersection of gender and race. Here, racism and sexism are examined concurrently using survey data from 204 African-American women residing in a southeastern U.S. urban city. Associations among racism, sexism, and stressful events across social roles and contexts (i.e., social network loss, motherhood and childbirth, employment and finances, personal illness and injury, and victimization) are investigated. Then, the relationships among these stressors on psychological distress are compared, and a moderation model is explored. Findings suggest that racism and …


The Effects Of Room Color On Stress Perception: Red Versus Green Environments, Teresa M. Kutchma Aug 2014

The Effects Of Room Color On Stress Perception: Red Versus Green Environments, Teresa M. Kutchma

Journal of Undergraduate Research at Minnesota State University, Mankato

The purpose of the study was to investigate the effects of red versus green room colors on individual perception of stress. Room color was found through previous studies to have specific effects on psychomotor activity and emotional states. Correlations were found between red room color and emotional and physical stimulation, while green was associated with inhibitory effects. Additionally, Goldstein’s theory of color perception showed that red has stimulating effects on human behavior. Subjects consisted of 15 female and 15 male college freshmen at Minnesota State University, Mankato. An experimental booth was used for red, green and white room conditions. Subjects …


Correlation Between Health And Stress, Hang Wu Aug 2014

Correlation Between Health And Stress, Hang Wu

Journal of Undergraduate Research at Minnesota State University, Mankato

This study examined participants’ level of stress and their perceived level of stress and success in school. The subjects were given the stress questionnaire in order to determine the level of stress they were experiencing and the frequency of health issues experienced during the previous year. The results of the study suggest that although level of stress may be similar between individuals, how they perceived the stress impacted their health level. Students who perceived the stress in a negative fashion were more likely to be sick than individuals who were less impacted by the stress. By identifying the correlation between …


Hair Cortisol As A Biomarker Of Stress In Mindfulness Training For Smokers., Simon B Goldberg, Alison R Manley, Stevens S Smith, Jeffrey M Greeson, Evan Russell, Stan Van Uum, Gideon Koren, James M Davis Aug 2014

Hair Cortisol As A Biomarker Of Stress In Mindfulness Training For Smokers., Simon B Goldberg, Alison R Manley, Stevens S Smith, Jeffrey M Greeson, Evan Russell, Stan Van Uum, Gideon Koren, James M Davis

College of Science & Mathematics Departmental Research

OBJECTIVES: Stress is a well-known predictor of smoking relapse, and cortisol is a primary biomarker of stress. The current pilot study examined changes in levels of cortisol in hair within the context of two time-intensity matched behavioral smoking cessation treatments: mindfulness training for smokers and a cognitive-behavioral comparison group.

PARTICIPANTS: Eighteen participants were recruited from a larger randomized controlled trial of smoking cessation.

OUTCOME MEASURES: Hair samples (3 cm) were obtained 1 month after quit attempt, allowing for a retrospective analysis of hair cortisol at preintervention and post-quit attempt time periods. Self-reported negative affect was also assessed before and after …


Career Decision Status, Career-Related Thinking, And Emotional Distress: A Structural Equation Model, Lindsey Marie Andrews Aug 2014

Career Decision Status, Career-Related Thinking, And Emotional Distress: A Structural Equation Model, Lindsey Marie Andrews

Dissertations

The choosing of a college major or occupation is an important decision with which many individuals struggle. Prior research has suggested that difficulty choosing a major or occupation affects a majority of students entering college and stems from multiple sources including lack of information, insufficient learning experiences, and ineffective decision-making processes. Cognitive-behavioral theory has shown utility in working with a diverse set of difficulties and with diverse populations through the examination of the influence of thoughts and emotions on resulting behavior. Research in the career literature has begun to emphasize connections between one’s thoughts and emotions in regards to career …


Addressing Self-Reported Depression, Anxiety, And Stress In College Students Via Web-Based Self-Compassionate Journaling, Jessica Rose Williamson Aug 2014

Addressing Self-Reported Depression, Anxiety, And Stress In College Students Via Web-Based Self-Compassionate Journaling, Jessica Rose Williamson

Electronic Theses and Dissertations

Depression, anxiety, and stress in the college undergraduate population have been steadily rising over the past decade. Trait self-compassion has been shown to be significantly and negatively related to perceptions of stress and symptoms of depression and anxiety. Research has indicated that self-compassion inductions are effective in increasing state self-compassion. In general, selfcompassion inductions are designed to be easily self-administered. Current research on Internetbased interventions indicates that self-administered therapeutic techniques are effective in reducing self-reported depression, anxiety, and stress. The goal of the current study was to compare the effects of self-compassionate journaling, narrative journaling, and a true control group …


Executive Control In Hispanic Children: Considering Linguistic And Sociocultural Factors, Miriam M. Martinez Jul 2014

Executive Control In Hispanic Children: Considering Linguistic And Sociocultural Factors, Miriam M. Martinez

Department of Psychology: Dissertations, Theses, and Student Research

Executive control represents a collection of high-order cognitive processes that are associated with important child outcomes, including academic achievement and social competencies. Despite the burgeoning interest in examining the development of executive control, less is known about the development of these skills among ethnic minority children. Hispanic children are currently the largest ethnic minority group in the United States and their diverse sociocultural and linguistic backgrounds provide an excellent context to study the influence of linguistic and sociocultural factors on the development of child executive control. The purpose of the three complementary studies reported in this dissertation is to contribute …


Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley Jul 2014

Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley

Faculty Publications

Background—Studies show that the hypothalamic–pituitary–adrenal (HPA) axis is dysregulated in depression. Some studies suggest that variation in the serotonin transporter genotype (hereafter 5HTT) modulates both risk for depression and psychopathological HPA axis responsiveness. Rhesus monkeys are well suited to model such relationships. Rhesus macaque models of human psychopathology have assessed the effect of the serotonin transporter (rh5HTT) on levels of cortisol in stressed subjects. These studies show that that under conditions of stress, heterozygous females (Ls) reared under adversity exhibit high levels of cortisol. Studies have not to our knowledge, however, assessed the potential additive effect on the cortisol response …