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Articles 3241 - 3270 of 4055
Full-Text Articles in Psychology
Residential Needs Of Adolescent Females: A Feminist Perspective, Elizabeth Manley
Residential Needs Of Adolescent Females: A Feminist Perspective, Elizabeth Manley
Antioch University Dissertations & Theses
With approximately 20,000 adolescent females living in residential treatment centers (RTCs) in the United States (Warner & Pottick, 2003), the need for RTCs that focus on meeting the unique developmental, psychological, and emotional needs of adolescent females is clear. Current research on the subject of adolescent females in residential treatment is largely focused on the overall efficacy of RTCs, rather than examining specific programmatic components offered to adolescent females in this treatment setting. While some research has been conducted that examines how to improve gender-specific RTCs, much of this research builds on socially constructed ideas of gender differences and often …
Linguistic Issues In Culturally Sensitive Assessment: A Rorschach Case Study, Lauren M. Weisberg
Linguistic Issues In Culturally Sensitive Assessment: A Rorschach Case Study, Lauren M. Weisberg
Antioch University Dissertations & Theses
The Rorschach Inkblot Test (“Rorschach”) has historically been viewed as a culturally sensitive assessment instrument because it utilizes nonverbal stimulus cards (Meyer, Viglione, Mihura, Erard, & Erdberg, 2011). As a result, it has been considered a more appropriate assessment tool for bilingual and multilingual patients than assessments which rely heavily on verbal language. However, there are no evidence-based practice recommendations for Rorschach assessment of bi- and multilingual patients, despite the incredible linguistic diversity in the United States and the widespread use of the Rorschach. This dissertation includes a case study of a multilingual French–Israeli immigrant who was admitted to an …
Forgotten Victims: Understanding Latino/A Non-Offending Parents Of Sexually Abused Children, Alba Rocio Andrade
Forgotten Victims: Understanding Latino/A Non-Offending Parents Of Sexually Abused Children, Alba Rocio Andrade
Antioch University Dissertations & Theses
Childhood sexual abuse is widely condemned by society and religion (Roesler & Wind, 1994; McCallum, 2001). Nevertheless, it is estimated that approximately one in three girls and one in six boys are sexually abused by the time they turn 18 years old (Stauffer and Deblinger, 1996). This trauma affects the victim as well as other members of the family including the non-offending parent(s). However, services are often provided only to the victimized child, which overlooks the needs of the non-offending parents. The existing body of research into the stressors experienced by non-offending parents typically is focused on non-offending parents of …
A Sociopolitical Perspective To Understand When And Why Supervisors Endorse And Implement Employees’ Suggested Changes, Huaizhong Chen
A Sociopolitical Perspective To Understand When And Why Supervisors Endorse And Implement Employees’ Suggested Changes, Huaizhong Chen
Graduate Theses, Dissertations, and Problem Reports (ETD)
When employees make suggestions for changes to their supervisors, they are providing raw materials potentially critical to the organization’s continuous improvement and adaptation. However, research suggests that supervisors do not always react favorably to employee voice behavior. The purpose of this study is to unravel the mediating and moderating mechanisms that can explain when and why employee voice behavior leads to supervisor endorsement and implementation. Specifically, taking a sociopolitical perspective, I argued that supervisor motive attributions for employee voice behavior can explain the extent to which supervisors endorse and subsequently implement employee voice. Furthermore, I argued that the mediating effects …
The Potential Promises And Pitfalls Of Using Local Norms For Gifted Identification, Marla S. Hartman
The Potential Promises And Pitfalls Of Using Local Norms For Gifted Identification, Marla S. Hartman
Graduate Theses, Dissertations, and Problem Reports (ETD)
Who are the gifted? This question has plagued the field since its inception. Historically, gifted education has been predicated on the values of the Caucasian, upper- to middle-class majority. As a result, underrepresentation of students from economically disadvantaged and culturally diverse families have been well documented in the literature and continues to this day. Some scholars have suggested the use of expanded definitions of giftedness to increase participation of students from underrepresented segments of the population. This study used regression and hierarchical linear models to predict the proportion of students identified across various thresholds focusing on how definitions impacted differential …
The Effects Of Reversing Safmeds Presentation On Learning And Generalization, Emily Nordlund
The Effects Of Reversing Safmeds Presentation On Learning And Generalization, Emily Nordlund
All Master's Theses
Say All Fast Minute Each Day (SAFMEDS) is a flashcard procedure that is effective in producing fluency, but not necessarily generalization, of a content area. One possibility for the lack of generalization is the direction of the SAFMEDS training. Most learners are presented with a definition (the longer side) and have to say the term (the shorter side). Elements of single-case and between-groups designs were used to examine the effects of reversing the direction of training on acquisition and fluency of SAFMEDS content, as well as generalization. Within this study, the control group was presented with a book or paper …
The Effects Of Therapy Balls On In-Seat And On-Task Behavior In Young Children, Ariel Ching
The Effects Of Therapy Balls On In-Seat And On-Task Behavior In Young Children, Ariel Ching
All Master's Theses
This study utilized an alternating treatment design to study the effects of therapy balls, chairs, and the element of choice on the in-seat and on-task behaviors of three, preschool-aged children. Participants were between 4 and 5 years old, typically developing, and were selected based on their ability to make a choice between two different stimuli. This study was conducted at a table, with the participant engaging in a fine-motor activity that they had shown preference to, based on a paired-stimulus preference assessment (Play-Doh, coloring, magnetic blocks, etc.). It was hypothesized that the participants would show higher rates of in-seat and …
Comparing The Effectiveness Of Verbal Feedback Versus Acoustical Feedback Within A Behavior Skills Training Package When Teaching Beginning Yoga Postures To Novice Yoga Practitioners, Molly Rauschl
All Master's Theses
Behavior skills training (BST), composed of modeling, instructions, rehearsal, and feedback, is an efficient and commonly used training package that has been proven effective in fostering behavior change in a variety of learners and with a multitude of behaviors, including those related to health and fitness. Feedback has been deemed a critical component of BST and there are various ways in which feedback can be administered. This study compared the effectiveness and efficiency of providing verbal feedback versus acoustical feedback within a BST package when teaching beginning yoga postures to participants who have never before practiced yoga. No feedback method …
Impacts Of Self-Efficacy On School Psychologists' Provisions Of Mental Health Services, Ashley Jantzer
Impacts Of Self-Efficacy On School Psychologists' Provisions Of Mental Health Services, Ashley Jantzer
All Master's Theses
The purpose of this thesis was to identify variables that predict a school psychologist’s self-efficacy in counseling abilities, as well as identify variables that predict perceived barriers to implementing mental health services to students in a school setting. Participants were 84 school psychologists working in the state of Washington. Participants were asked to complete a survey that included (a) demographic questions, (b) a questionnaire about perceived self-efficacy in counseling abilities, and (c) a questionnaire about perceived barriers to providing mental health services. The results of two multiple linear regression equations suggest that in this study, certain variables predicted both self-efficacy …
Music, Video And Perception: An Investigation Into Shaping Attitudes Toward Fish And Their Natural Habitat, Kayla-Ann Hemmings
Music, Video And Perception: An Investigation Into Shaping Attitudes Toward Fish And Their Natural Habitat, Kayla-Ann Hemmings
All Master's Theses
The current study investigated the influence of music and video on perceptions of fish, willingness to help aquatic conservation efforts, and attitudes about the marine environment. Participants were randomly distributed to one of six groups which varied by presenting information about marine life in a video format or through printed text (i.e., video or pamphlet) and on the background music that played during the presentation of that information (i.e., ominous, uplifting, or no sound). Participants, then, completed several counterbalanced measures, including rating how much six different words (i.e., three positive and three negative) applied to fish, Willingness to Conserve questions …
Integrated Primary Care: Development Of A Patient Satisfaction Measure, Sarah C. Pearson
Integrated Primary Care: Development Of A Patient Satisfaction Measure, Sarah C. Pearson
Antioch University Dissertations & Theses
Primary care is often the first stop for individuals seeking services for a variety of behavioral health concerns including mental health and substance use disorders. However, many such patients are inadequately treated in these settings. Integrated primary care addresses this issue by adding a behavioral health provider to the primary care team to improve care and patient outcomes. A growing body of evidence suggests that increased integration of behavioral health and primary care yields a variety of significant outcomes including improved patient care, increased access to mental health treatment, and increased patient and provider satisfaction. When thinking about healthcare improvement …
Introducing Shame Resilience To Women Who Struggle With Complex Trauma And Substance Abuse, Kirsten R. Robertson
Introducing Shame Resilience To Women Who Struggle With Complex Trauma And Substance Abuse, Kirsten R. Robertson
Antioch University Dissertations & Theses
The relationship between shame and trauma has been documented in research beginning as early as the 19th century. Not until the second half of the 20th century did extensive research clearly define both trauma and shame, with the addition of Posttraumatic Stress Disorder (PTSD) as an official diagnosis in the field of mental health. Many researchers and clinicians believe an additional diagnosis should be added to the list of trauma-related mental health diagnoses—one that includes repeated traumatic experiences during childhood. Despite the known relationship between shame and various traumatic experiences, direct shame interventions have yet to find a place in …
Helping Animals, Helping Ourselves: Reciprocal Benefits Of Prosocial Behaviors Directed Toward Animals, Casey A. Culligan
Helping Animals, Helping Ourselves: Reciprocal Benefits Of Prosocial Behaviors Directed Toward Animals, Casey A. Culligan
Antioch University Dissertations & Theses
This is a dissertation project on the reciprocal benefits—to volunteers and animals—of volunteering at animal shelters, rescues, and sanctuaries. I have provided a brief literature review on the relationship between prosociality and helper/recipient wellbeing, highlighting the current scarcity of research on the human enactment of prosocial behavior with animal recipients of help. I then further supported the need for continued research in this regard by examining the emerging body of research on the suggested wellbeing-benefits of human–animal interaction. An ecopsychological framework was utilized to emphasize the potential therapeutic affects (to both humans and animals) of engaging in prosocial behaviors directed …
Graduate Student Competencies In Working With Lesbian, Gay, And Bisexual Youth, Rachael Roberts
Graduate Student Competencies In Working With Lesbian, Gay, And Bisexual Youth, Rachael Roberts
Antioch University Dissertations & Theses
The focus and purpose of this dissertation was to explore students’ who are enrolled in APA-accredited clinical psychology doctoral programs self-perceived competency levels for working with LGB youth. This research utilized the Sexual Orientation Counselor Competency Scale (SOCCS; Bidell, 2005) in conjunction with an experience and demographic questionnaire. A survey was sent to all APA-accredited clinical psychology doctoral programs and all responses were analyzed through correlational analysis. The primary research question dealt with the possibility of a relationship between access and utilization of doctoral program training (in class or otherwise), practicum experiences, and level of confidence that graduate students have …
Examining Nurse Resiliency & A Mindfulness-Based Stress Reduction Intervention To Prevent Nurse Burnout, Allegra Grannell
Examining Nurse Resiliency & A Mindfulness-Based Stress Reduction Intervention To Prevent Nurse Burnout, Allegra Grannell
Posters
Nurses continually give of themselves at work, as well as outside of work. This results in extensive stress, physiological distress, and ultimately burnout for individuals in the nursing profession. Nurses that work in high-stress environments, such as critical care, pediatrics, and oncology, are at a significantly increased risk of manifesting physical and psychological symptoms of burnout syndrome, compassion fatigue, and post-traumatic stress disorder (PTSD). Many of these factors are leading to nurses leaving the profession prematurely, resulting in significantly high turnover rates. High burnout and turnover rates of nurses result in the lack of adequate nursing staff in hospitals, which …
Correlational Study Between Emotional Intelligence And The Use Of Online Dating, Aleksander E. Mansdoerfer
Correlational Study Between Emotional Intelligence And The Use Of Online Dating, Aleksander E. Mansdoerfer
Undergraduate Psychology Research Methods Journal
This study sought to answer if there is a correlational relationship between an individual’s emotional intelligence quotient and individual use of dating applications such as tinder or bumble. Participants from the Lindenwood University Participant Pool and the researcher’s social network were asked to answer anonymously to a two-part survey. The first part of the survey had the participants self rate their emotional intelligence by answer nineteen questions, and the second part of the study asked questions about an individuals habits and experience with online dating applications. A total of 77 participants completed the study, and their ages ranged between 18 …
The Relationship Between Methods Of Calculating The Ahi And Daytime Sleepiness, Severity Of Sleep Apnea, And Cpap Pressure Settings, Kathryn J. Kane
The Relationship Between Methods Of Calculating The Ahi And Daytime Sleepiness, Severity Of Sleep Apnea, And Cpap Pressure Settings, Kathryn J. Kane
Walden Dissertations and Doctoral Studies
Sleep apnea impacts one's mental and physical health, and has social consequences which affect all of society. Not only is there is a weak correlation between the severity of sleep apnea and daytime sleepiness as reported on the Epworth Sleepiness Scale (ESS), but there is also a weak correlation between the severity of sleep apnea and prescribed treatment as indicated by 95th percentile pressure on a continuous positive airway pressure (CPAP) machine. This poses difficulty for providers as well as patients throughout screening and treatment. The purpose of this study was to use a biopsychosocial approach to perform a within-subjects …
Eye Tracking And Decision-Making In A Hypothetical Severe Weather Event, S J. Johnson, L E. Swinney, C E. Martin, M R. Allen, S A. Sabro, E M. Tumminello, S Edmonds, G Carrasco, E Kinnamon
Eye Tracking And Decision-Making In A Hypothetical Severe Weather Event, S J. Johnson, L E. Swinney, C E. Martin, M R. Allen, S A. Sabro, E M. Tumminello, S Edmonds, G Carrasco, E Kinnamon
Psychology and Sociology
Inadequate warning systems are a major factor contributing to many fatalities and injuries during severe weather situations (Balluz, Schieve, Holmes, Kiezak, & Malilay, 2000); therefore, the National Weather Service (NWS) continues to update warning systems and methods to better suit a wider range of individuals.
Emerging Adults’ Experiences Of Agency In Higher Education Decisions, Leah B. Benjamin
Emerging Adults’ Experiences Of Agency In Higher Education Decisions, Leah B. Benjamin
Antioch University Dissertations & Theses
Over the past several decades, there has been a cultural shift impacting the experience of individuals in their late-teens to mid-20s in the United States. These individuals undergo a time of “cultural limbo,” during which the lines between adolescence and adulthood are blurred. The term emerging adulthood describes this distinct developmental period, which fits within the context of Erikson’s preexisting stages of psychosocial development (Arnett, 2014). A challenge for emerging adults is coming to terms with some of their more adult-like responsibilities in life. This requires making complex decisions that will impact their lives for many years to come, such …
Family Estrangement And Hospital Readmission Rates Among Severely Mentally Ill Adults, Jenna A. Gunnels
Family Estrangement And Hospital Readmission Rates Among Severely Mentally Ill Adults, Jenna A. Gunnels
Antioch University Dissertations & Theses
Most crisis stabilization, and mental health treatment in general, is delivered solely to the individual in crisis, by professionals who are careful to protect the individual’s right to privacy. An unintended consequence of this objective, unfortunately, can be the undermining of the potentially significant role played by family members in the treatment, maintenance, and stabilization of individuals with mental illness. Without family involvement, some individuals burdened by mental illness slowly and steadily decline. This study investigates how familial relationships impact mental health problems, specifically psychiatric hospital readmissions. The goal of this study is to determine whether being estranged from one’s …
Veterans’ Help-Seeking And Spousal Support For Ptsd: A Preliminary Study, Kimberly S. Sollows
Veterans’ Help-Seeking And Spousal Support For Ptsd: A Preliminary Study, Kimberly S. Sollows
Antioch University Dissertations & Theses
Continued engagement in military conflicts and known underutilization of mental health services by veterans necessitates understanding of factors influencing veterans’ attitudes about mental health treatment and decisions to seek services. The present study examined relationships between posttraumatic stress disorder (PTSD) symptom severity, perceived support from spouse, and attitudes toward mental health help-seeking among married U.S. veterans. Participants (N =39) were recruited using social media outreach, an online gaming platform, and through print fliers. First, it was hypothesized that perceived spousal support would be significantly positively correlated with attitudes toward treatment seeking, which was supported to a moderate degree (r=.345, p=.031). …
อิทธิพลของความคล้ายคลึงเชิงรูปลักษณ์ และการรับรู้การควบคุมได้ ที่มีผลต่อการรับรู้ความเหมือนมนุษย์ ความเชื่อใจ และการยอมรับต่อหุ่นยนต์, กฤตภัค วรเมธพาสุข
อิทธิพลของความคล้ายคลึงเชิงรูปลักษณ์ และการรับรู้การควบคุมได้ ที่มีผลต่อการรับรู้ความเหมือนมนุษย์ ความเชื่อใจ และการยอมรับต่อหุ่นยนต์, กฤตภัค วรเมธพาสุข
Chulalongkorn University Theses and Dissertations (Chula ETD)
งานวิจัยนี้มีจุดประสงค์เพื่อศึกษาความสัมพันธ์ระหว่างปัจจัยทางด้านการรับรู้ความเหมือนมนุษย์ที่มีต่อความไว้วางและการยอมรับหุ่นยนต์ตามแนวคิดทฤษฎี S-E-E-K ที่นำมาใช้สร้างกรอบแนวคิดหลักในการวิจัยนี้ โดยมีปัจจัยทางด้านความคล้ายคลึงเชิงรูปลักษณ์เป็นตัวแปรต้น การรับรู้การควบคุมได้เป็นตัวแปรกำกับ และแรงจูงใจทางสังคมเป็นตัวแปรควบคุม กลุ่มตัวอย่างคือ นิสิตจำนวน 200 คน อายุระหว่าง 18-25 ปี ใช้การสุ่มอย่างเป็นระบบร่วมกับการสุ่มอย่างง่ายเข้าหนึ่งใน 4 เงื่อนไข โดยให้ผู้เข้าร่วมการวิจัยดูรูปภาพและอ่านข้อความคุณสมบัติของหุ่นยนต์ที่มีการจัดกระทำให้มีความคล้ายคลึงมนุษย์และพฤติกรรมที่คาดเดา/ควบคุมได้ของหุ่นยนต์ที่แตกต่างกันในแต่ละเงื่อนไข จากนั้นตอบแบบสอบถามการรับรู้ความเหมือนมนุษย์ ความไว้วางใจหุ่นยนต์ การยอมรับหุ่นยนต์ ผลจากการวิเคราะห์เส้นทาง พบว่า ความคล้ายคลึงเชิงรูปลักษณ์มีผลต่อการรับรู้ความเหมือนมนุษย์ที่มีต่อหุ่นยนต์อย่างมีนัยสำคัญทางสถิติ โดยในเงื่อนไขที่มีการรับรู้การควบคุมและคาดเดาไม่ได้ ทำให้อิทธิพลของความคล้ายคลึงเชิงรูปลักษณ์ที่มีต่อการรับรู้ความเหมือนมนุษย์เพิ่มมากขึ้น ยิ่งไปกว่านั้น หุ่นยนต์ที่มีความคล้ายคลึงมนุษย์สูง และบุคคลไม่สามารถควบคุมหรือคาดเดาพฤติกรรมของหุ่นยนต์ได้ ทำให้บุคคลรู้สึกว่าหุ่นยนต์มีความเหมือนมนุษย์มากขึ้น ซึ่งส่งผลต่อความไว้วางใจ รวมถึงการยอมรับหุ่นยนต์
Interactions Between Inflammation And Female Sexual Desire And Arousal Function, Tierney K. Lorenz
Interactions Between Inflammation And Female Sexual Desire And Arousal Function, Tierney K. Lorenz
Department of Psychology: Faculty Publications
Purpose of Review—To describe the current state of research on interactions between inflammation and female sexual function.
Recent findings—Inflammation may interfere with female sexual desire and arousal via direct (neural) and indirect (endocrine, vascular, social/behavioral) pathways. There are significant sex differences in the effect of inflammation on sexual function, arising from different evolutionary selection pressures on regulation of reproduction. A variety of inflammation-related conditions are associated with risk of female sexual dysfunction, including cardiovascular disease, metabolic syndrome, and chronic pain.
Summary—Clinical implications include the need for routine assessment for sexual dysfunction in patients with inflammation-related conditions, the potential for anti-inflammatory …
Verbal Descriptions Of Cue Direction Affect Object Desirability, Jason Tipples, Mike Dodd, Jordan Grubaugh, Alan Kingstone
Verbal Descriptions Of Cue Direction Affect Object Desirability, Jason Tipples, Mike Dodd, Jordan Grubaugh, Alan Kingstone
Department of Psychology: Faculty Publications
Approach-avoidance behaviors are observed across a broad range of species. For humans, we tend move toward things we like, and away from things we dislike. Previous research tested whether repeatedly shifting visuo-spatial attention toward an object in response to eye gaze cues can increase liking for that object. Here, we tested whether a gaze-liking effect can occur for verbal descriptions of looking behavior without shifts of attention. Also, we tested the gaze specificity hypothesis – that the liking effect is specific to gaze cues – by comparing the effect of different types of cue (pointing gestures and arrow cues). In …
The Effect Of Health Literacy On Chronic Kidney Disease Patient Health Outcomes, Mia Castagnero
The Effect Of Health Literacy On Chronic Kidney Disease Patient Health Outcomes, Mia Castagnero
Honors Theses
The current study seeks to enhance knowledge of health literacy among patients diagnosed with CKD. Identifying gaps in kidney-specific health literacy may help direct specific interventions to improve patient education and support. The goal of the current study is to investigate the associations between health literacy (general health literacy and kidney-specific health literacy) and patient health outcomes, such as medication adherence and barriers in access to care.
It's Written All Over Your Face : Examining The Relationship Between Socioeconomic Status And Empathic Accuracy, Megan Roherbeck Wirtz
It's Written All Over Your Face : Examining The Relationship Between Socioeconomic Status And Empathic Accuracy, Megan Roherbeck Wirtz
Honors Theses
What, exactly, is the relationship between socioeconomic status (SES) and emotional intelligence? Is it possible that emotional intelligence can explain the well-established positive relationship between SES and wellbeing? The purpose of this study was to investigate a) a potential mediational pathwaybetween SES, emotional intelligence, and wellbeing and b) conflicting research in the relationship between SES and emotional intelligence. This study was conducted using avariety of measures of socioeconomic status and wellbeing, as well as a performance-based measure of empathic accuracy.
When Does The Positivity Effect Emerge? : Age-Related Emotional Biases At Encoding And Retrieval, Hannah Wolfe
When Does The Positivity Effect Emerge? : Age-Related Emotional Biases At Encoding And Retrieval, Hannah Wolfe
Honors Theses
The Socioemotional Selectivity Theory (SST) posits that as their future time perspective shrinks, older adults tend to be more motivated by emotionally meaningful goals and therefore experience what is called the “positivity effect” with age (Carstensen, 2006). The positivity effect had been studied in both attention biases (Isaacowitz et al., 2006a) and memory biases (Kensinger, 2008), with older adults dwelling longer on and better remembering the positive stimuli over the negative. Yet, few studies have measured emotional biases at both the encoding and retrieval phases, which is why this study uses eye-tracking to determine whether any biases in gaze patterns …
Driving Anxiety In Young People With Autism Spectrum Disorder : A Driving Simulator Pilot Study, Rebecca Pasch
Driving Anxiety In Young People With Autism Spectrum Disorder : A Driving Simulator Pilot Study, Rebecca Pasch
Honors Theses
The goal of this project was to investigate how driving anxiety changes overtime in young people with autism spectrum disorder (ASD) when using a driving simulator technology. Additional exploratory measures were collected on duration of participation,. stopping distance, and reaction time.
Posttraumatic Stress And Parenting Behaviors: The Mediating Role Of Emotion Regulation, Shaina A. Kumar, Molly R. Franz, Rebecca L. Brock, David Dilillo
Posttraumatic Stress And Parenting Behaviors: The Mediating Role Of Emotion Regulation, Shaina A. Kumar, Molly R. Franz, Rebecca L. Brock, David Dilillo
Department of Psychology: Faculty Publications
Maternal trauma has been linked with problematic parenting, including both harsh and permissive behaviors. However, little is known about mechanisms accounting for this association. The current study examined the potential impact of posttraumatic stress disorder (PTSD) and emotion regulation on dysfunctional parenting behaviors in a sample of community mothers. We hypothesized a mediation model wherein PTSD would be associated with dysfunctional parenting (i.e., lax and overreactive behaviors) indirectly through deficits in maternal emotion regulation. Seventy-eight community mothers of 18- to 36-month-old children were administered the Clinician Administered PTSD Scale for DSM-5 (CAPS-5) and 19 mothers met criteria for PTSD. Mothers …
Dnmt3a In The Hippocampal Ca1 Is Crucial In The Acquisition Of Morphine Self‐Administration In Rats, Jian-Jun Zhang, Feng-Ze Jiang, Wei Zheng, Ying Duan, Su-Bo Jin, Fang Shen, Jing Liang, Ming Li, Nan Sui
Dnmt3a In The Hippocampal Ca1 Is Crucial In The Acquisition Of Morphine Self‐Administration In Rats, Jian-Jun Zhang, Feng-Ze Jiang, Wei Zheng, Ying Duan, Su-Bo Jin, Fang Shen, Jing Liang, Ming Li, Nan Sui
Department of Psychology: Faculty Publications
Drug‐reinforced excessive operant responding is one fundamental feature of long-lasting addiction‐like behaviors and relapse in animals. However, the transcriptional regulatory mechanisms responsible for the persistent drug‐specific (not natural rewards) operant behavior are not entirely clear. In this study, we demonstrate a key role for one of the de novo DNA methyltransferase, DNMT3a, in the acquisition of morphine self‐administration (SA) in rats. The expression of DNMT3a in the hippocampal CA1 region but not in the nucleus accumbens shell was significantly up‐regulated after 1‐ and 7‐day morphine SA (0.3 mg/kg/infusion) but not after the yoked morphine injection. On the other hand, saccharin …