Open Access. Powered by Scholars. Published by Universities.®

Psychology Commons

Open Access. Powered by Scholars. Published by Universities.®

University of Kentucky

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 571 - 600 of 860

Full-Text Articles in Psychology

Doing Envy Justice: Examining The Politics Of Envy, Charles E. Hoogland Jan 2016

Doing Envy Justice: Examining The Politics Of Envy, Charles E. Hoogland

Theses and Dissertations--Psychology

Conservatives and liberals disagree about the underlying motivations driving opposition to concentrated wealth. Liberals contend that such objections are often driven by legitimate fairness concerns, whereas conservatives frequently cite envy instead. Research and theory suggest that two particularly important contextual questions with respect to emotional reactions to wealth are its source (inherited or earned), and how that wealth is put to use, which could interactively and differentially influence liberals’ and conservatives’ reactions to affluent individuals. The current study aimed to empirically address whether liberals actually are more prone to envy than conservatives, both in general and in response to specific …


Understanding Alcohol Use Trajectories From Adolescence To Young Adulthood: A Bioecological Approach, Jacqueline A. Bonsu Jan 2016

Understanding Alcohol Use Trajectories From Adolescence To Young Adulthood: A Bioecological Approach, Jacqueline A. Bonsu

Theses and Dissertations--Psychology

The current study sought to better understand how alcohol use patterns develop over the transition to young adulthood by taking a bioecological approach in examining the joint influence of contextual and individual factors on drinking behaviors. Using a longitudinal design to include many factors that likely play key roles in this highly sensitive developmental period (e.g., peer norms, social activities, personality traits, access and exposure to substances), both mean levels of these variables and their change over time were considered in relation to alcohol use trajectories (AUTs). Participants were 525 students ages 18 to 25 recruited from the introductory psychology …


Loss Aversion In Cocaine Users: Influence Of Risk And Commodity Type, Justin Charles Strickland Jan 2016

Loss Aversion In Cocaine Users: Influence Of Risk And Commodity Type, Justin Charles Strickland

Theses and Dissertations--Psychology

Numerous studies in behavioral economics have demonstrated that individuals are more sensitive to the prospect of a loss than a gain (i.e., loss aversion). Although loss aversion has been well described in healthy populations, little research exists in individuals with substance use disorders. The purpose of this study was to comprehensively evaluate loss aversion in cocaine users. Participants completed measures designed to assess loss aversion for drug and non-drug commodities under varying risk conditions. Cocaine demand was determined using a cocaine purchase task. Cocaine users showed a loss aversion score that was consistent across commodity and risk conditions. Compared to …


Ovarian Hormones, Adhd, Risk-Taking, & Impulsivity, Bethan A. Roberts Jan 2016

Ovarian Hormones, Adhd, Risk-Taking, & Impulsivity, Bethan A. Roberts

Theses and Dissertations--Psychology

Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly impairing disorder of inattention, hyperactivity, and impulsivity that is more frequently diagnosed in males versus females at a ratio of 3:1. However, females with the disorder become highly impaired during adolescence, perhaps due to the onset of cycling ovarian hormones at puberty. The present study empirically assessed the role of the major female sex hormones, estrogen and progesterone, in the presentation of ADHD symptoms, impulsivity, and associated risk-taking behaviors (e.g., risky sex, substance use and abuse) in a non-clinical sample of young adult women. 32 healthy young adult women who were screened for hormonal …


The Effect Of Victim Religion On Juror Perceptions Of Hate Crimes, Casey Magyarics Jan 2016

The Effect Of Victim Religion On Juror Perceptions Of Hate Crimes, Casey Magyarics

Theses and Dissertations--Psychology

The present study investigated mock juror perceptions of hate crimes in the courtroom, specifically whether a victim’s religion (Atheist, Christian, Jewish, or Muslim) influenced the likelihood that a mock juror would render a hate crime verdict. I employed a mock juror methodology where participants read an assault trial summary, rendered a verdict, and answered a series of rating questions about the victim and defendant. Two theoretical explanations were proposed to explain the main effect of victim religion on participant verdict decisions; that participants would be most likely to render a guilty verdict when the victim is considered an in-group member …


Pulling The Trigger On Disarming Domestic Violence Abusers: Implementing Gun Confiscation Policy In Urban And Appalachian Kentucky, Kellie R. Lynch Jan 2016

Pulling The Trigger On Disarming Domestic Violence Abusers: Implementing Gun Confiscation Policy In Urban And Appalachian Kentucky, Kellie R. Lynch

Theses and Dissertations--Psychology

The present study investigated why communities differing in culture and resources are willing and able to implement gun confiscation as part of a protective order. Specifically, this study explored whether the perceived risk of intimate partner homicide and gun violence, benefits to engaging in gun confiscation, barriers to gun confiscation, community norms about guns, and community readiness to implement gun confiscation: (a) differ in urban and rural communities, (b) are perceived differently by victim service and justice system key professionals within urban and rural communities, and (c) are related to if a community is able and willing to consistently implement …


Decision-Making Processes, Driving Performance, And Acute Responses To Alcohol In Dui Offenders, Walter Roberts Jan 2016

Decision-Making Processes, Driving Performance, And Acute Responses To Alcohol In Dui Offenders, Walter Roberts

Theses and Dissertations--Psychology

Alcohol-impaired driving is a major cause of motor vehicle accident and death in the United States. People who are arrested for DUI (Driving under the Influence) are at high risk to reoffend; approximately one in three of these individuals will commit another DUI offense in the three years following their first conviction (Nochajski & Stasiewicz, 2006). This high risk for recidivism in these individuals suggests that cognitive characteristics may contribute to a pattern of pathological decision making leading to impaired driving. Indeed, individuals with a history of DUI report higher rates of impulsiveness and behavioral dysregulation compared to their nonoffending …


Friend Over Foe: Friendship Quality And Chronic Peer Victimization, Kristin E. Landfield Sep 2015

Friend Over Foe: Friendship Quality And Chronic Peer Victimization, Kristin E. Landfield

Kaleidoscope

The present research builds on the extensive literature in the field of peer victimization. Specifically, it examines whether friendship acts as a buffer in the relation between implicit socio-cognitive biases and peer victimization among 82 children ages 9-13. Children completed two implicit measures of victimization in order to detect cognitive biases in socioemotional processing among chronically victimized children. Levels of friendship quality were assessed and shown to have a main effect on peer victimization indices. The emotional Stroop task related negatively to peer victimization, indicating a cognitive avoidance of emotionally-salient stimuli. The IAT and peer victimization were related such that …


Relations Among Gender-Typical And Gender-Atypical Uses Of Aggression, Popularity, And Depression, Melissa Murphy Sep 2015

Relations Among Gender-Typical And Gender-Atypical Uses Of Aggression, Popularity, And Depression, Melissa Murphy

Kaleidoscope

The purpose of this study was to investigate how types of bullying engaged in by high school students (relational, physical, or verbal aggression) vary with gender and how they may be related to a student’s social status. Children in the ninth grade, from four different Kentucky high schools, were administered various measures as part of a larger study on social development in their own classroom. Measures used in our analysis included a bully and victim self-reported narrative, Bullying Questions and Belonging Questionnaire, and a Peer Nomination Scale. Results indicated that females used more relational aggression than males, and males used …


“In A Competition Full Of Hamburgers, You’Re A Steak:” American Idol And The Role Of Reality Television In The Maintenance Of Our Egos, Kathryn L. Braun Sep 2015

“In A Competition Full Of Hamburgers, You’Re A Steak:” American Idol And The Role Of Reality Television In The Maintenance Of Our Egos, Kathryn L. Braun

Kaleidoscope

Over the past decade, reality shows have ascended to the top of the Nielsen rating charts and have assumed a dominance that is difficult to cast aside. One such reality show, American Idol has grown in popularity over its last six seasons. This chapter discusses one of the main arguments of a larger honors thesis that examines the underlying motives that keep American viewers watching. As a cultural commodity, American Idol can be viewed as a product of American values and holds a societal purpose for its viewers. Therefore, the arguments within this chapter propose that the great popularity enjoyed …


Developmental Changes In Analytic And Holistic Processes In Face Perception, Jane E. Joseph, Michelle D. Dibartolo, Ramesh S. Bhatt Aug 2015

Developmental Changes In Analytic And Holistic Processes In Face Perception, Jane E. Joseph, Michelle D. Dibartolo, Ramesh S. Bhatt

Psychology Faculty Publications

Although infants demonstrate sensitivity to some kinds of perceptual information in faces, many face capacities continue to develop throughout childhood. One debate is the degree to which children perceive faces analytically versus holistically and how these processes undergo developmental change. In the present study, school-aged children and adults performed a perceptual matching task with upright and inverted face and house pairs that varied in similarity of featural or 2nd order configural information. Holistic processing was operationalized as the degree of serial processing when discriminating faces and houses [i.e., increased reaction time (RT), as more features or spacing relations were …


Negative Urgency And Lack Of Perseverance: Identification Of Differential Pathways Of Onset And Maintenance Risk In The Longitudinal Prediction Of Nonsuicidal Self-Injury, Elizabeth N. Riley, Jessica L. Combs, Carol E. Jordan, Gregory T. Smith Jul 2015

Negative Urgency And Lack Of Perseverance: Identification Of Differential Pathways Of Onset And Maintenance Risk In The Longitudinal Prediction Of Nonsuicidal Self-Injury, Elizabeth N. Riley, Jessica L. Combs, Carol E. Jordan, Gregory T. Smith

Psychology Faculty Publications

Many researchers have identified impulsivity-related personality traits as correlates of and risk factors for nonsuicidal self-injury (NSSI). Using a longitudinal design, we tested the hypothesis that one such trait, negative urgency (the tendency to act rashly when distressed), predicts the onset of NSSI during the first year of college and a different trait, lack of perseverance (the disposition to fail to maintain focus on tasks that are difficult or boring), predicts the maintenance of NSSI during the first year of college. In a sample of n = 1,158 college women (mean age = 18.04, 95% of participants were 18 at …


Brief Report: Evidence Of Ingroup Bias On The Shooter Task In A Saudi Sample, Timothy P. Schofield, Timothy Deckman, Christopher P. Garris, C. Nathan Dewall, Thomas F. Denson Mar 2015

Brief Report: Evidence Of Ingroup Bias On The Shooter Task In A Saudi Sample, Timothy P. Schofield, Timothy Deckman, Christopher P. Garris, C. Nathan Dewall, Thomas F. Denson

Psychology Faculty Publications

When predominantly White participants in Western countries are asked to shoot individuals in a computer game who may carry weapons, they show a greater bias to shoot at outgroup members and people stereotyped as dangerous. The goal was to determine the extent to which shooter biases in the Middle East would vary as a function of target ethnicity and culturally appropriate or inappropriate headgear. Within a sample of 37 male Saudi Arabian residents, we examined shooter biases outside of Western nations for the first time. Targets in this task were either White or Middle Eastern in appearance, and wore either …


Husband's Response To Infidelity, Toby Q. Jenkins Jan 2015

Husband's Response To Infidelity, Toby Q. Jenkins

Theses and Dissertations--Family Sciences

Infidelity is the most often cited reason for divorce in the United States and much of the world. Providing therapy for a couple trying to recover from infidelity is one of the most difficult and complex presenting problems for therapists. Much of the existing research that predicts responses to infidelity subscribes to an evolutionary psychology perspective, predicting response by gender differently based on motives concerning procreation. Males would find sexual infidelity more threatening because paternity would be uncertain, females would find emotional infidelity more threatening because of the risk of resources and protection being diverted to another female’s offspring. Much …


Leadership Training For A Diverse World: A Study Of The Effectiveness Of Three Interventions With Fraternity And Sorority Leaders, Kirsten A. Gonzalez Jan 2015

Leadership Training For A Diverse World: A Study Of The Effectiveness Of Three Interventions With Fraternity And Sorority Leaders, Kirsten A. Gonzalez

Theses and Dissertations--Educational, School, and Counseling Psychology

Lesbian and gay college students face heterosexist and homophobic attitudes and behaviors from their heterosexual peers (Burn, 2000; Fine, 2011; Franklin, 2000; Rankin, 2003; Silverschanz, Cortina, Konik, & Magley, 2008; Woodford, Howell, Silverschanz, & Yu, 2012; & Yost & Gilmore, 2011). Greek fraternity and sorority organizations can contribute to and influence the heterosexist and homophobic climate on college campuses. Greek organizations offer leadership opportunities, community engagement, and a sense of belonging, but these organizations can also perpetuate a climate of hostility and rejection of lesbian and gay peers (Case, 1996; Case, Hesp, & Eberly, 2005; DeSantis, 2007; Rankin et al., …


Examining The Neuroprotective Properties Of 3-Dimethoxybenzylidene-Anabasine (Dmxb-A) In A Third Trimester Chronic Ethanol Exposure Model In Rats, Logan J. Fields Jan 2015

Examining The Neuroprotective Properties Of 3-Dimethoxybenzylidene-Anabasine (Dmxb-A) In A Third Trimester Chronic Ethanol Exposure Model In Rats, Logan J. Fields

Theses and Dissertations--Psychology

Excitotoxicity caused by ethanol (ETOH) withdrawal (EWD) is highly detrimental to the developing brain. Targeting this excitotoxicity has been shown to be a promising approach for improving outcome following developmental ETOH exposure. Activation of nicotinic acetylcholine receptors (nAChR), in the central nervous system can be protective against EWD. We examined the ability of DMXB-A, a α7 nAChR agonist, to reduce neurotoxicity caused by EWD in the hippocampus. To test this, an organotypic hippocampal slice culture was used. Slices were exposed to ETOH (100mM) or control medium. After 10 days, the slices were treated with DMXB-A (1, 3, or 10uM) …


Safety Concerns, Fear And Precautionary Behavior Among College Women: An Exploratory Examination Of Two Measures Of Residency, Adam J. Pritchard, Carol E. Jordan, Pamela Wilcox Jan 2015

Safety Concerns, Fear And Precautionary Behavior Among College Women: An Exploratory Examination Of Two Measures Of Residency, Adam J. Pritchard, Carol E. Jordan, Pamela Wilcox

Office for Policy Studies on Violence Against Women Publications

This study examines the impact of two distinct measures of residency on college women's perceptions of safety, fear of crime and precautionary behaviors within both on-campus and off-campus areas. A student's current residency either on- or off-campus and a student's prior residency in a metropolitan, micropolitan or rural county prior to college are compared across these three aspects of campus safety. Current residency is found to be significantly related to a student's perceptions of safety in off-campus areas around campus, as well as the likelihood of engaging in precautionary behaviors such as avoiding specific locations on campus or carrying or …


Dissociable Roles Of Dopamine And Serotonin Transporter Function In A Rat Model Of Negative Urgency, Justin R. Yates, Mahesh Darna, Cassandra D. Gipson, Linda P. Dwoskin, Michael T. Bardo Jan 2015

Dissociable Roles Of Dopamine And Serotonin Transporter Function In A Rat Model Of Negative Urgency, Justin R. Yates, Mahesh Darna, Cassandra D. Gipson, Linda P. Dwoskin, Michael T. Bardo

Psychology Faculty Publications

Negative urgency is a facet of impulsivity that reflects mood-based rash action and is associated with various maladaptive behaviors in humans. However, the underlying neural mechanisms of negative urgency are not fully understood. Several brain regions within the mesocorticolimbic pathway, as well as the neurotransmitters dopamine (DA) and serotonin (5-HT), have been implicated in impulsivity. Extracellular DA and 5-HT concentrations are regulated by DA transporters (DAT) and 5-HT transporters (SERT); thus, these transporters may be important molecular mechanisms underlying individual differences in negative urgency. The current study employed a reward omission task to model negative urgency in rats. During reward …


Gabapentin Alleviates Affective Pain After Traumatic Nerve Injury, Ryan B. Griggs, Michael T. Bardo, Bradley K. Taylor Jan 2015

Gabapentin Alleviates Affective Pain After Traumatic Nerve Injury, Ryan B. Griggs, Michael T. Bardo, Bradley K. Taylor

Psychology Faculty Publications

Gabapentin reduces behavioral signs of stimulus-evoked allodynia and hyperalgesia in preclinical studies of traumatic nerve injury, but its effects on more clinically relevant measures of stimulus-independent pain are unclear. To address this gap, we determined whether gabapentin would relieve affective pain after spared nerve injury (SNI). Twelve days after sham or SNI surgery, we administered gabapentin over three consecutive conditioning days and then evaluated conditioned place preference. Gabapentin produced conditioned place preference and reversed mechanical hypersensitivity in SNI but not sham rats at a dose (100 mg/kg) that did not change open-field activity. These results show for the first time …


R-Bpidi, An Α6Β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release And Nicotine Reinforcement, Joshua S. Beckmann, Andrew C. Meyer, Marharyta Pivavarchyk, David B. Horton, Guangrong Zheng, Andrew M. Smith, Thomas E. Wooters, J. Michael Mcintosh, Peter A. Crooks, Michael T. Bardo, Linda P. Dwoskin Jan 2015

R-Bpidi, An Α6Β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release And Nicotine Reinforcement, Joshua S. Beckmann, Andrew C. Meyer, Marharyta Pivavarchyk, David B. Horton, Guangrong Zheng, Andrew M. Smith, Thomas E. Wooters, J. Michael Mcintosh, Peter A. Crooks, Michael T. Bardo, Linda P. Dwoskin

Psychology Faculty Publications

α6β2* nicotinic acetylcholine receptors (nAChRs) expressed by dopaminergic neurons mediate nicotine-evoked dopamine (DA) release and nicotine reinforcement. α6β2* antagonists inhibit these effects of nicotine, such that α6β2* receptors serve as therapeutic targets for nicotine addiction. The present research assessed the neuropharmacology of 1,10-bis(3-methyl-5,6-dihydropyridin-1(2H)-yl)decane (r-bPiDI), a novel small-molecule, tertiary amino analog of its parent compound, N,N-decane-1,10-diyl-bis-3-picolinium diiodide (bPiDI). bPiDI was previously shown to inhibit both nicotine-evoked DA release and the reinforcing effects of nicotine. In the current study, r-bPiDI inhibition of [3H]nicotine and [3H]methyllycaconitine binding sites was evaluated to assess interaction with the recognition binding sites on …


Emotional Enhancement And Repetition Effects During Working Memory In Persons With Mild Cognitive Impairment, Lucas S. Broster Jan 2015

Emotional Enhancement And Repetition Effects During Working Memory In Persons With Mild Cognitive Impairment, Lucas S. Broster

Theses and Dissertations--Clinical and Translational Science

This dissertation introduces a framework for understanding differences in how emotional enhancement effects might influence memory in aging adults and then summarizes the findings of three studies of how repetition effects and emotional enhancement effects influence working memory in older adults without cognitive impairment (NC), older adults with amnestic mild cognitive impairment (MCI), and older adults with mild Alzheimer’s disease (AD). In these experiments, individuals with AD showed cognitive impairment in terms of accuracy and reaction time, but individuals with MCI showed milder behavioral impairment that was confined to manipulations of working memory. Individuals with AD showed relative sparing of …


Explore The Relationship Among Lung Cancer Stigma, Social Support, And Psychosocial Distress, Lisa Maggio Jan 2015

Explore The Relationship Among Lung Cancer Stigma, Social Support, And Psychosocial Distress, Lisa Maggio

Theses and Dissertations--Nursing

There is longstanding causal relationship between cigarette smoking and lung cancer. Smoke-free policies and anti-smoking campaigns have been linked to the decline in smoking acceptance and contribute to the unintended consequence of stigmatizing smokers. Lung cancer is viewed as a self-inflicted disease and patients’ feel judged in a manner different from other cancers affecting social interactions between family, friends, and healthcare professionals. Lung cancer stigma contributes to depression, anxiety, poor self-esteem, guilt, shame, blame, threatens a person’s social identity, and limits social support that deeply affects patients and their support persons.

This dissertation contains a review of the literature related …


Adhd Children And Mental Health Service Use: Maternal Determinants, Katarina Krizova Jan 2015

Adhd Children And Mental Health Service Use: Maternal Determinants, Katarina Krizova

Theses and Dissertations--Family Sciences

The current study investigated maternal determinants of mental health service use, namely, individual child therapy, among preadolescent children diagnosed with ADHD. The Behavioral Model of Health Care Utilization (Andersen, 2008) was used as a theoretical framework for the study. Data from the last three rounds of ECLS-K dataset were employed to test a longitudinal model using Bayesian analysis. Socio-demographic variables and maternal mental health were tested as exogenous variables and mother-child relationship variables, discipline variables, and perceived maternal concern about child’s overall behavior and child’s emotional symptoms were tested as intervening variables. Results showed that only maternal mental health remained …


The Impact Of Video Chatting On Idealization And Disillusionment For Long Distance Dating Couples, Laura Kusisto Jan 2015

The Impact Of Video Chatting On Idealization And Disillusionment For Long Distance Dating Couples, Laura Kusisto

Theses and Dissertations--Family Sciences

Previous research indicates a high rate of long distance relationships, especially among young adults. Yet, research in this area is lacking, particularly regarding the role of video chatting. Through the lens of the media richness theory and the hyperpersonal model, this qualitative study explores how video chatting impacts idealization and disillusionment in young adults’ long distance dating relationships. Data was collected through semi-structured interviews with both partners of six heterosexual couples. Data was analyzed using the constant comparative approach and following the basic framework of open, axial, and selective coding used in grounded theory research. Results indicate that video chatting …


Transgender Individuals' Social Support Experiences In Central Appalachia, Angela J. Aaron Jan 2015

Transgender Individuals' Social Support Experiences In Central Appalachia, Angela J. Aaron

Theses and Dissertations--Educational, School, and Counseling Psychology

The majority of empirical studies in transgender psychology have focused on the negative experiences of urban transgender individuals (Grossman & D’Augelli, 2007; Koken, Bimbi, & Parsons, 2009; Melendez & Pinto, 2007; Singh & McKleroy, 2011; Strain & Shuff, 2010; Xavier, Bobbin, Singer, & Budd, 2005). Less is known about the experiences of rural transgender individuals (Fassinger & Arseneau, 2007; Grossman, 2008) especially in Central Appalachia (Gray, 2009). The purpose of this study was to examine transgender individuals’ perceptions of social support in Central Appalachia. Bronfenbrenner’s (1977) ecological model framed the analysis of social support experiences within the culture of Central …


Examining Memory Consolidation And Reconsolidation In An Appetitive Pavlovian Task, Jonathan J. Chow Jan 2015

Examining Memory Consolidation And Reconsolidation In An Appetitive Pavlovian Task, Jonathan J. Chow

Theses and Dissertations--Psychology

Memory plays an important role in defining how one behaves. The neurobiological mechanisms of memory have been studied extensively in animal models and the NMDA glutamate receptor has been identified to play an important role in the consolidation and reconsolidation of appetitive memories. Certain memories, depending on what was learned, can function differently and can be more difficult to disrupt based on a number of factors. Currently, no study has examined whether or not a reward-predictive stimulus attributed with incentive value is more difficult to disrupt than a stimulus that functions as a general reward-predictor. To determine the role of …


Effect Of Environmental Enrichment On Dopamine And Serotonin Transporters And Glutamate Neurotransmission In Medial Prefrontal And Orbitofrontal Cortex, Mahesh Darna, Joshua S. Beckmann, Cassandra D. Gipson, Michael T. Bardo, Linda P. Dwoskin Jan 2015

Effect Of Environmental Enrichment On Dopamine And Serotonin Transporters And Glutamate Neurotransmission In Medial Prefrontal And Orbitofrontal Cortex, Mahesh Darna, Joshua S. Beckmann, Cassandra D. Gipson, Michael T. Bardo, Linda P. Dwoskin

Psychology Faculty Publications

Recent studies have reported that rats raised in an enriched condition (EC) have decreased dopamine transporter (DAT) function and expression in medial prefrontal cortex (mPFC), as well as increased d-amphetamine-induced glutamate release in nucleus accumbens compared to rats raised in an isolated condition (IC). In these previous studies, DAT function and expression were evaluated using mPFC pooled from four rats for each condition to obtain kinetic parameters due to sparse DAT expression in mPFC. In contrast, accumbal glutamate release was determined using individual rats. The current study extends the previous work and reports on the optimization of DAT and serotonin …


Pharmacological Manipulation Of Glucocorticoid Receptors Differentially Affects Cocaine Self-Administration In Environmentally Enriched And Isolated Rats, Rebecca S. Hofford, Mark A. Prendergast, Michael T. Bardo Jan 2015

Pharmacological Manipulation Of Glucocorticoid Receptors Differentially Affects Cocaine Self-Administration In Environmentally Enriched And Isolated Rats, Rebecca S. Hofford, Mark A. Prendergast, Michael T. Bardo

Psychology Faculty Publications

Social isolation rearing (isolated condition, IC) is used as a model of early life stress in rodents. Rats raised in this condition are often compared to rats raised in an environmentally enriched condition (EC). However, EC rats are repeatedly exposed to forced novelty, another classic stressor in rodents. These studies explored the relationship between cocaine self-administration and glucocorticoid receptor (GR) activation and measured total levels of GR protein in reward-related brain regions (medial prefrontal cortex, orbitofrontal cortex, nucleus accumbens, amygdala) in rats chronically exposed to these conditions. For Experiment 1, rats were housed in EC or IC and were then …


Role Of Ionotropic Glutamate Receptors In Delay And Probability Discounting In The Rat, Justin R. Yates, Seth R. Batten, Michael T. Bardo, Joshua S. Beckmann Jan 2015

Role Of Ionotropic Glutamate Receptors In Delay And Probability Discounting In The Rat, Justin R. Yates, Seth R. Batten, Michael T. Bardo, Joshua S. Beckmann

Psychology Faculty Publications

Rationale Discounting of delayed and probabilistic reinforcement is linked to increased drug use and pathological gambling. Understanding the neurobiology of discounting is important for designing treatments for these disorders. Glutamate is considered to be involved in addiction-like behaviors; however, the role of ionotropic glutamate receptors (iGluRs) in discounting remains unclear.

Objectives The current study examined the effects of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor blockade on performance in delay and probability discounting tasks.

Methods Following training in either delay or probability discounting, rats (n=12, each task) received pretreatments of the NMDA receptor antagonists MK-801 (0, 0.01, 0.03, 0.1, …


Role Of Serotonin Transporter Function In Rat Orbitofrontal Cortex In Impulsive Choice, Mahesh Darna, Jonathan J. Chow, Justin R. Yates, Richard J. Charnigo, Joshua S. Beckmann, Michael T. Bardo, Linda P. Dwoskin Jan 2015

Role Of Serotonin Transporter Function In Rat Orbitofrontal Cortex In Impulsive Choice, Mahesh Darna, Jonathan J. Chow, Justin R. Yates, Richard J. Charnigo, Joshua S. Beckmann, Michael T. Bardo, Linda P. Dwoskin

Psychology Faculty Publications

Impulsivity is a multi-faceted personality construct that plays a prominent role in drug abuse vulnerability. Dysregulation of 5-hydroxytryptamine (serotonin, 5-HT) systems in subregions of the prefrontal cortex has been implicated in impulsivity. Extracellular 5-HT concentrations are regulated by 5-HT transporters (SERTs), indicating that these transporters may be important molecular targets underlying individual differences in impulsivity and drug abuse vulnerability. The present study evaluated the role of SERT in mediating individual differences in impulsivity. Rats were tested for both impulsive action using the cued go/no-go task and for impulsive choice using a delay discounting task in a counterbalanced design. Following behavioral …