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Articles 181 - 210 of 339

Full-Text Articles in Cognitive Science

Identifying Youth Appeals In Alcohol Alternative Social Media Content Through Framing, Melina Oneal Jan 2024

Identifying Youth Appeals In Alcohol Alternative Social Media Content Through Framing, Melina Oneal

West Chester University Master’s Theses

Proposed regulations for alcohol advertising prevent beverage companies from targeting people under the legal drinking age. However, similar regulations for alcohol alternative beverages are less explored, which could allow alcohol alternative products to create awareness for alcoholic beverages among youth. Alcohol alternatives beverages, including no-alcohol and low-alcohol products, are increasing in popularity and can function as compliments to alcoholic products to decrease the total alcohol volume consumed or as substitutes for alcoholic products. Framing theory can be operationalized through the Content Appealing to Youth Index, an index of content elements found in research literature to be appealing to youth, to …


"Ruskiy Mir" And "Ukrainskyi Svit": Ontological And Anthropological Antagonists, Liudmyla Fylypovych, Oksana Horkusha Jan 2024

"Ruskiy Mir" And "Ukrainskyi Svit": Ontological And Anthropological Antagonists, Liudmyla Fylypovych, Oksana Horkusha

Occasional Papers on Religion in Eastern Europe

The article focuses on a crucial issue of global interest--attempts of the Russian Federation to reformat the world according to the worldview model of the "Ruskiy mir." The paradigm of the "Ruskiy mir" assumes a system of values (ontological, anthropological, theological, and historiographical ideas and behavioral models) programmed by the entire russian history, as defined by russian culture, traditions, and the russian worldview. According to the "Russian worldview," the world should have a different structure, and the global international system should have a different format: Moscow (the Russian Empire and the Russian Federation) should be at the center of the …


Interpersonal Skills In A Sociotechnical System: A Training Gap In Flight Decks, Kimberly Perkins, Sourojit Ghosh, Crystal Hall Jan 2024

Interpersonal Skills In A Sociotechnical System: A Training Gap In Flight Decks, Kimberly Perkins, Sourojit Ghosh, Crystal Hall

Journal of Aviation/Aerospace Education & Research

This research analyzed the perceptions of interpersonal skills on established aviation safety models, Crew Resource Management (CRM), and Threat and Error Management (TEM) using feedback from industry pilots. The flight deck is a sociotechnical system where much research has focused on the technical aspect, whereas we spotlight its socio aspect. The aviation industry must invest in training pilots on interpersonal skills to enhance safety through increased efficacy of safety models integrated throughout existing training programs. A 34-question survey was disseminated across both commercial and business aviation pilots (N=822). We explored three research questions regarding pilots’ perceived training on interpersonal skills …


Human-Ai Teams In Aviation: Considerations From Human Factors And Team Science, Jenna Korentsides, Joseph R. Keebler, Crystal M. Fausett, Sabina M. Patel, Elizabeth H. Lazzara Jan 2024

Human-Ai Teams In Aviation: Considerations From Human Factors And Team Science, Jenna Korentsides, Joseph R. Keebler, Crystal M. Fausett, Sabina M. Patel, Elizabeth H. Lazzara

Journal of Aviation/Aerospace Education & Research

Artificial Intelligence (AI) has transformed the way human-computer interaction (HCI) teams can collaborate and coordinate in various domains, including aviation and crew resource management (CRM). AI's transformative capabilities enhance teamwork, efficiency, and safety, particularly in risk management. AI's ability to process vast amounts of data and provide real-time insights enables informed decision-making and automation of repetitive tasks in aviation. By combining the strengths of AI and humans, outlined in our modified version of the ‘HABA-MABA’ framework, a dynamic teamwork relationship emerges, provided roles are successfully allocated. AI systems are able to act as intelligent assistants, offering timely recommendations, fostering effective …


Catching Up To Yesterday: An Argument For A Practical Application Of Creativity For Inspiring Change From A Content-Based Course Delivery To A 21st-Century Skills-Based Delivery, Darren Chapman Jan 2024

Catching Up To Yesterday: An Argument For A Practical Application Of Creativity For Inspiring Change From A Content-Based Course Delivery To A 21st-Century Skills-Based Delivery, Darren Chapman

Creativity and Change Leadership Graduate Student Master's Projects

This project is a creative vision for how college-level courses could be changed to deliver the most important skills students need in the 21st century—moving toward an essential employability skills-based delivery process while training vocational (content) skills. Technology is outpacing humans' ability to adapt and adopt to it, making it increasingly difficult to keep pace with technological change. This has wide-ranging effects on each of us – productively, emotionally, and perhaps physically. Colleges are at the forefront of educating citizens about the working world to improve their productivity, incomes and their sense of intrinsic motivation. However, these same colleges are …


Music Density: A Novel Measurement Of Music Perception, Tyler Ussery Jan 2024

Music Density: A Novel Measurement Of Music Perception, Tyler Ussery

All Master's Theses

Empirical research in fields such as music perception, cognition, and therapy has developed considerably in recent decades. While many studies implement musical stimuli, there are few expeditious metrics for identifying the objective characteristics of music itself. The current study proposed and developed a tool for measuring perception of the theoretical concept of music density. Music density can be defined as the compactness of auditory information that comprises a piece of music. For this study, five musical factors were explored (tempo, texture, timbre, dynamics, and predictability) via a 5-point Likert scale. It is well established that personality is an important …


Perception, Attention, And Action! A New Perspective On The Associations Found In Educational Expertise And Visual Search, Ashley Sawyer Jan 2024

Perception, Attention, And Action! A New Perspective On The Associations Found In Educational Expertise And Visual Search, Ashley Sawyer

Honors Program Theses

Expertise as defined in literature is the peak or otherwise exceptionally high levels of performance on a particular task or within a given domain (Papesh et al., 2021). In this study, expertise is defined as the time length the individual has spent in their field. For the purpose of this research, an expert can exist in a plethora of fields ranging from history and music to mathematics or science. Becoming an expert requires for the individual to not only have the mental and cognitive concepts that come with acquiring this type of knowledge, but it also incorporates skills they know …


Exploring Usability In Exercise Interventions: From Conceptualization To Measurement And Application, Anne Inger Mørtvedt Jan 2024

Exploring Usability In Exercise Interventions: From Conceptualization To Measurement And Application, Anne Inger Mørtvedt

Dissertations, Master's Theses and Master's Reports

Exercise interventions hold promise for preventing and treating numerous conditions, diseases, and injuries. However, these interventions will only be effective if they are being used. Unfortunately, uptake and adherence to prescribed exercise and physical activity guidelines are insufficient. Some reasons for this include lack of knowledge, resources, flexibility, and enjoyment. Exercise program developers need to not only consider the effectiveness of the program during the development phase, but also involve end-users and receive feedback on program usability to determine likelihood of uptake and adoption. Usability testing can be used to detect barriers to use and implementation likelihood but has not …


Reporting On Un Security Council: Decoding Media Bias, Alessandra Loiero Jan 2024

Reporting On Un Security Council: Decoding Media Bias, Alessandra Loiero

Dissertations and Theses

This thesis explores Western media's representation of the United Nations (UN), focusing on the Security Council's role in global conflict resolution. It examines how UN-accredited correspondents perceive the effectiveness of the Security Council, particularly when the body faces deadlock. The study employs text analysis techniques to identify biases and perceptions in media coverage, using The New York Times' reporting on the Ukraine conflict as a case study. It illuminates framing effects in journalistic narratives, revealing how journalists subtly interject their views when reporting, often revealing unrealistic expectations and shedding light on the limitations of the UN's mandate or its inability …


Exploring Spatial Operations Of Distractor Suppression In The Sense Of Touch, Nicole A. Serino Jan 2024

Exploring Spatial Operations Of Distractor Suppression In The Sense Of Touch, Nicole A. Serino

Dissertations and Theses

The ability to select sensory information in our environment is key to facilitating goal-directed actions. Sensory selection mechanisms are prevalent in all sensory modalities, and can be implemented by enhancing information at the relevant location and/or suppressing neural information outside the focus of attention (a mechanism known as distractor suppression). Although we have a decent understanding of how the brain enhances information within the focus of attention, less is known about the mechanisms that mediate suppression of distractors, especially in sensory modalities outside vision. In this study, we conducted a series of behavioral experiments to investigate the spatial flexibility of …


The Construct Validity Of The Reynolds Intellectual Assessment Scales, Second Edition (Rias-2) And The Wechsler Abbreviated Scale Of Intelligence, Second Edition (Wasi-Ii), Cristen J. Rozek Jan 2024

The Construct Validity Of The Reynolds Intellectual Assessment Scales, Second Edition (Rias-2) And The Wechsler Abbreviated Scale Of Intelligence, Second Edition (Wasi-Ii), Cristen J. Rozek

Masters Theses

This study is designed to assess the relationship between two brief intelligence tests, the Reynolds Intellectual Assessment Scales-Second Edition (RIAS-2; Reynolds & Kamphaus, 2015) and the Wechsler Abbreviated Scale of Intelligence-Second Edition (WASI-II; Wechsler, 2011), through evaluating their ability to similarly measure intellectual skills. These two tests measure an individual’s overall general intelligence. Both tests are able to assess individuals aged 6-90. The WASI-II publisher specified this test was only a screener while the RIAS-2 is not. Tests like the RIAS-2 and WASI-II are more time efficient allowing more time to be spent on other professional responsibilities. Manuals from both …


Empowering Children With Special Needs (Cwsn) In Computer Science: An Interactive Hand Gestures Approach To Number Conversion Teaching, Renjith P.R., Jeeva Jose Jan 2024

Empowering Children With Special Needs (Cwsn) In Computer Science: An Interactive Hand Gestures Approach To Number Conversion Teaching, Renjith P.R., Jeeva Jose

Journal of Educational Technology Development and Exchange (JETDE)

It is essential for teachers to effectively address the diverse needs of students within the classroom environment, encompassing variations in IQ, communication skills, problem-solving abilities, and mathematical proficiency. Ensuring the inclusion of CwSN (Children with Special Needs) is imperative to prevent social division in the classroom. While the department offers accommodations such as scribes, interpreters, or extra time for examinations, these measures may not fully address the specific needs of CwSN. This study explores the efficacy of employing hand gestures as a teaching tool for CwSN in computer science, particularly in the realm of number conversions. A machine learning-based tool …


Enhancing Students’ User Experience With A Code Critiquer, Laura E. Albrant Jan 2024

Enhancing Students’ User Experience With A Code Critiquer, Laura E. Albrant

Dissertations, Master's Theses and Master's Reports

This thesis explores the role of human factors in the realm of code critiquers and students’ experiences with them. Across three studies, the work utilized Design Thinking to improve the user experience of WebTA for introductory engineering students learning MATLAB. The first two studies gathered observational and interview data to empathize, define, and ideate a new user interface (UI). Said UI was prototyped and then tested with the third study. Overall, the surveys’ data suggests that most students found the new design to be more appealing, useful, and purposeful; however, there is still plenty of room for improvement. Additionally, analysis …


The Influence Of Visual Perspective On The Cognitive Effort Required For Mental Representation, Jeffrey P. Hong Jan 2024

The Influence Of Visual Perspective On The Cognitive Effort Required For Mental Representation, Jeffrey P. Hong

Theses and Dissertations (Comprehensive)

Mental representation is the process by which an individual simulates an event in their mind’s eye. This process is the foundation of the ability to remember the past, engage in prospective thinking, or imagine fictitious scenarios. An individual can mentally represent any event through their own eyes—the first-person perspective or from the viewpoint of an external observer—the third-person perspective. The perspective of representation influences outcomes related to memory, visuospatial processing, affect, social cognition, clinical diagnoses, and language processing. In turn, an individual’s tendency to favour either perspective is shaped by related factors.

The current research consists of four experiments, designed …


Effects Of Screen Time On Children's Brain Development: A Scoping Review, Niloofar Jannesar, Todd E. Davenport, Lindsay Gietzen Dec 2023

Effects Of Screen Time On Children's Brain Development: A Scoping Review, Niloofar Jannesar, Todd E. Davenport, Lindsay Gietzen

Pacific Journal of Health

In this scoping review, the effects of screen time on cognitive, linguistic, and social-emotional development in children were studied by examining peer-reviewed articles published between 2018 and 2023. A total of 17 peer-reviewed articles were used in the study. The research reported that screen media provide a learning avenue, though it could be detrimental when children spend their time watching more than appropriate screen media. Furthermore, the study indicated that excessive screen media use may harm children’s executive function, which affects academic performance and language development. Related studies have also shown a correlation between excess screen use and problems like …


Direct Relationships Between The Five Internal Senses: The Extremes And In-Between Of The Inner Experience, Sydnie Hoyt, Camryn O'Neal, Miranda Brannum, Sara Bagley Dec 2023

Direct Relationships Between The Five Internal Senses: The Extremes And In-Between Of The Inner Experience, Sydnie Hoyt, Camryn O'Neal, Miranda Brannum, Sara Bagley

The Confluence

Inner experience of all 5 modalities were investigated to determine if there were correlations amongst them and how visual mental imagery and internal hearing were used in an applied story. Our sample (N = 137) completed the Vividness of Visual Imagery Questionnaire (VVIQ; Marks, 1973) and the Plymouth Sensory Imagery Questionnaire (Psi-Q; Andrade et al., 2013) to obtain trait measures of the different modalities within the inner experience. Results showed statistically significant positive correlations between each of the trait measures of the 5 sensory modalities (visual mental imagery, inner hearing, taste, smell, and touch). Based on their VVIQ total scores, …


Clausewitzian Theory Of War In The Age Of Cognitive Warfare, Amber Brittain-Hale, Amber Brittain-Hale Dec 2023

Clausewitzian Theory Of War In The Age Of Cognitive Warfare, Amber Brittain-Hale, Amber Brittain-Hale

Education Division Scholarship

We can reconceptualise warfare by contrasting Clausewitz with the modern practice of cognitive warfare, as evidenced by Ukraine’s defence methodologies. The strategic orchestration of ‘infopolitik’ and the sophisticated use of social media can shape narratives and public perception. This article revisits Clausewitz’s tenet of war as a political instrument and juxtaposes it with contemporary conflict’s multidimensional tactics. By scrutinising Ukraine’s digital and psychological warfare tactics, one may question the applicability of Clausewitz’s framework, seeking to understand if these novel dimensions of warfare compel a redefinition or an expansion of his thesis to navigate the complexities of contemporary geopolitical confrontations.


Mrs. Dalloway As A Window For Understanding Life, Kristen Venegas Dec 2023

Mrs. Dalloway As A Window For Understanding Life, Kristen Venegas

English (MA) Theses

Virginia Woolf’s Mrs. Dalloway may be dismissed as fiction, and fiction consequently is dismissed as fantasy. However, the novel enables readers to practice an intellectual exercise of meta-awareness that extends beyond the pages and onto real world phenomena. Under a cognitive neuroscience perspective, Mrs. Dalloway is a literary masterpiece due to its hyper- realistic execution of the intimacies of life. Through the narrative style of free-indirect discourse, Woolf illustrates what occurs in the minds of characters as they develop their own perceptions of reality and identity, exposes the fear and inadequacies of mankind’s distress in times of chaos and disorder …


Value Added By Using Joint Displays In Mixed Methods Research, Elizabeth Svoboda Dec 2023

Value Added By Using Joint Displays In Mixed Methods Research, Elizabeth Svoboda

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Mixed methods research collects, analyzes, and integrates rigorous qualitative and quantitative methods to gain a deeper understanding of a phenomenon than would be gained by using either method alone. Integration is one of the key features of mixed methods research and consists of mixing qualitative and quantitative research in a systematic way to generate new inferences or follow-up studies. However, the process of integration can be challenging to draw on expertise in both qualitative and quantitative methods, decide when and how to integrate qualitative and quantitative research, and combine multiple data sources in a coherent way to generate new inferences. …


What’S In A Word? A Study Of Emotional Valence, Trisha Patel, Cameron Smith, Olivia Williams, Raul Rodriguez-Calva Nov 2023

What’S In A Word? A Study Of Emotional Valence, Trisha Patel, Cameron Smith, Olivia Williams, Raul Rodriguez-Calva

Science University Research Symposium (SURS)

Cognitive stress affects humans mentally and physically, and specifically may impact emotional recognition. Previous studies have focused on the perceived emotional valence of nouns vs. adjectives and the emotional recognition of photographs. While this has led to the creation of an emotional valence database, there has yet to be a study to explore how stress can change perceived emotional valence. Using data from the Affective Norms for English Words (ANEW), the Portland Arithmetic Stress Test (PAST), and the Montreal Imaging Stress Task (MIST), a study was created to explore how participants emotional valence of words would change after being placed …


Book Review: Kings, Conquerors, Psychopaths: From Alexander To Hitler To The Corporation, Tim Bakken Nov 2023

Book Review: Kings, Conquerors, Psychopaths: From Alexander To Hitler To The Corporation, Tim Bakken

Genocide Studies and Prevention: An International Journal

The book Kings, Conquerors, Psychopaths is a survey of a vast amount of human wrongdoing. It lays bare the motivations of aggressors who wish to subjugate nations or groups of people and corporate executives and government bureaucrats who make discretionary decisions that harm people. Along with cataloging mass killings by despots and soldiers, the book includes stories about Ponzi-schemers and the deaths of automobile drivers and passengers who were killed by vehicle defects known to the manufacturer. The book posits that “[p]owerful, elite forces are trying to force us backward toward a non-democratic state, one where power, wealth, and prerogative …


Oh No, We're Moving, Devina Parker Nov 2023

Oh No, We're Moving, Devina Parker

Psychology Division Scholarship

This wonderful book helps children identify and express their feelings, face the challenges that come with moving to a new place, and ease difficult emotions such as worry and fear. Devina's compassionate storytelling and insightful guidance provide invaluable support to young readers and their families during times of transition.


Motivational Interviewing May Resolve Vaccine Hesitancy, Scott L. Baughan Oct 2023

Motivational Interviewing May Resolve Vaccine Hesitancy, Scott L. Baughan

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using:

Gagneur A, Lemaître T, Gosselin V, et al. A postpartum vaccination promotion intervention using motivational interviewing techniques improves short-term vaccine coverage: PromoVac study. BMC public health. 2018;18(1):811. https://doi.org/10.1186/s12889-018-5724-y

for a juvenile patient with a caregiver who is skeptical about the safety of routine vaccinations.


Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil Oct 2023

Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil

Research Colloquium

Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using …


The Science Of Learning: Understanding The Learning Process And Its Implementation Into The Classroom, Robert Hawkins Sep 2023

The Science Of Learning: Understanding The Learning Process And Its Implementation Into The Classroom, Robert Hawkins

The Cardinal Edge

College and higher education is often seen as the next step for many students pursuing a particular career or field. These institutions strive to facilitate learning and maintain a rewarding academic environment. However, students often face various challenges when first attending college which is reflected by high levels of dropout and withdrawal from general education courses, especially for first-time students. In fact, according to the education data initiation, “at 4-year institutions, 18.4% of first-time, full-time college freshmen dropped out between 2019 and 2020” (Hansen & Checked, 2022). One of these challenges is understanding the process of learning on a fundamental …


Physical Time Within Human Time Sep 2023

Physical Time Within Human Time

The International Journal of Ecopsychology (IJE)

A possible solution is offered to help resolve the “two times problem” regarding the veridical and illusory nature of time. First it is recognized that the flow (passage) of time is part of a wider array of temporal experiences referred to as manifest time, all of which need to be reconciled. Then, an information gathering and utilizing system (IGUS) model is used as a basis for a view of manifest time. The model IGUS robot of Hartle that solves the “unique present” debate is enhanced with veridical and (corresponding) illusory components of not only the flow of time but also …


Ufo Witness Testimony (Reliability)--'Flyer' Sep 2023

Ufo Witness Testimony (Reliability)--'Flyer'

The International Journal of Ecopsychology (IJE)

No abstract provided.


Multiancestry Analysis Of The Hla Locus In Alzheimer’S And Parkinson’S Diseases Uncovers A Shared Adaptive Immune Response Mediated By Hla-Drb1*04 Subtypes, Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar De Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatrice Arosio, Michael E Belloy, Luisa Benussi, Anne Boland, Barbara Borroni, María J Bullido, Paolo Caffarra, Jordi Clarimon, Antonio Daniele, Daniel Darling, Stéphanie Debette, Jean-François Deleuze, Martin Dichgans, Carole Dufouil, Emmanuel During, Emrah Düzel, Daniela Galimberti, Guillermo Garcia-Ribas, José María García-Alberca, Pablo García-González, Vilmantas Giedraitis, Oliver Goldhardt, Caroline Graff, Edna Grünblatt, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Henne Holstege, Jakub Hort, Yoo Jin Jung, Deckert Jürgen, Silke Kern, Teemu Kuulasmaa, Kun Ho Lee, Ling Lin, Carlo Masullo, Patrizia Mecocci, Shima Mehrabian, Alexandre De Mendonça, Mercè Boada, Pablo Mir, Susanne Moebus, Fermin Moreno, Benedetta Nacmias, Gael Nicolas, Shumpei Niida, Børge G Nordestgaard, Goran Papenberg, Janne Papma, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Oliver Peters, Yolande A L Pijnenburg, Gerard Piñol-Ripoll, Julius Popp, Laura Molina Porcel, Raquel Puerta, Jordi Pérez-Tur, Innocenzo Rainero, Inez Ramakers, Luis M Real, Steffi Riedel-Heller, Eloy Rodriguez-Rodriguez, Owen A Ross, Luis Jose Royo, Dan Rujescu, Nikolaos Scarmeas, Philip Scheltens, Norbert Scherbaum, Anja Schneider, Davide Seripa, Ingmar Skoog, Vincenzo Solfrizzi, Gianfranco Spalletta, Alessio Squassina, John Van Swieten, Raquel Sánchez-Valle, Eng-King Tan, Thomas Tegos, Charlotte Teunissen, Jesper Qvist Thomassen, Lucio Tremolizzo, Martin Vyhnalek, Frans Verhey, Margda Waern, Jens Wiltfang, Jing Zhang, Eadb, Gr@Ace Study Group, Degesco Consortium, Demgene, Eadi, Gerad, Asian Parkinson’S Disease Genetics Consortium, Henrik Zetterberg, Kaj Blennow, Zihuai He, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G Kehoe, Ole A Andreassen, Cornelia Van Duin, Magda Tsolaki, Pascual Sánchez-Juan, Ruth Frikke-Schmidt, Kristel Sleegers, Tatsushi Toda, Anna Zettergren, Martin Ingelsson, Yukinori Okada, Giacomina Rossi, Mikko Hiltunen, Jungsoo Gim, Kouichi Ozaki, Rebecca Sims, Jia Nee Foo, Wiesje Van Der Flier, Takeshi Ikeuchi, Alfredo Ramirez, Ignacio Mata, Agustín Ruiz, Ziv Gan-Or, Jean-Charles Lambert, Michael D Greicius, Emmanuel Mignot Sep 2023

Multiancestry Analysis Of The Hla Locus In Alzheimer’S And Parkinson’S Diseases Uncovers A Shared Adaptive Immune Response Mediated By Hla-Drb1*04 Subtypes, Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar De Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatrice Arosio, Michael E Belloy, Luisa Benussi, Anne Boland, Barbara Borroni, María J Bullido, Paolo Caffarra, Jordi Clarimon, Antonio Daniele, Daniel Darling, Stéphanie Debette, Jean-François Deleuze, Martin Dichgans, Carole Dufouil, Emmanuel During, Emrah Düzel, Daniela Galimberti, Guillermo Garcia-Ribas, José María García-Alberca, Pablo García-González, Vilmantas Giedraitis, Oliver Goldhardt, Caroline Graff, Edna Grünblatt, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Henne Holstege, Jakub Hort, Yoo Jin Jung, Deckert Jürgen, Silke Kern, Teemu Kuulasmaa, Kun Ho Lee, Ling Lin, Carlo Masullo, Patrizia Mecocci, Shima Mehrabian, Alexandre De Mendonça, Mercè Boada, Pablo Mir, Susanne Moebus, Fermin Moreno, Benedetta Nacmias, Gael Nicolas, Shumpei Niida, Børge G Nordestgaard, Goran Papenberg, Janne Papma, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Oliver Peters, Yolande A L Pijnenburg, Gerard Piñol-Ripoll, Julius Popp, Laura Molina Porcel, Raquel Puerta, Jordi Pérez-Tur, Innocenzo Rainero, Inez Ramakers, Luis M Real, Steffi Riedel-Heller, Eloy Rodriguez-Rodriguez, Owen A Ross, Luis Jose Royo, Dan Rujescu, Nikolaos Scarmeas, Philip Scheltens, Norbert Scherbaum, Anja Schneider, Davide Seripa, Ingmar Skoog, Vincenzo Solfrizzi, Gianfranco Spalletta, Alessio Squassina, John Van Swieten, Raquel Sánchez-Valle, Eng-King Tan, Thomas Tegos, Charlotte Teunissen, Jesper Qvist Thomassen, Lucio Tremolizzo, Martin Vyhnalek, Frans Verhey, Margda Waern, Jens Wiltfang, Jing Zhang, Eadb, Gr@Ace Study Group, Degesco Consortium, Demgene, Eadi, Gerad, Asian Parkinson’S Disease Genetics Consortium, Henrik Zetterberg, Kaj Blennow, Zihuai He, Julie Williams, Philippe Amouyel, Frank Jessen, Patrick G Kehoe, Ole A Andreassen, Cornelia Van Duin, Magda Tsolaki, Pascual Sánchez-Juan, Ruth Frikke-Schmidt, Kristel Sleegers, Tatsushi Toda, Anna Zettergren, Martin Ingelsson, Yukinori Okada, Giacomina Rossi, Mikko Hiltunen, Jungsoo Gim, Kouichi Ozaki, Rebecca Sims, Jia Nee Foo, Wiesje Van Der Flier, Takeshi Ikeuchi, Alfredo Ramirez, Ignacio Mata, Agustín Ruiz, Ziv Gan-Or, Jean-Charles Lambert, Michael D Greicius, Emmanuel Mignot

Faculty, Staff and Students Publications

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. …


The Neural Correlates Of Bodily Self-Consciousness In Virtual Worlds, Evan A. Owens Sep 2023

The Neural Correlates Of Bodily Self-Consciousness In Virtual Worlds, Evan A. Owens

Dissertations, Theses, and Capstone Projects

Bodily Self-Consciousness (BSC) is the cumulative integration of multiple sensory modalities that contribute to our sense of self. Sensory modalities, which include proprioception, vestibulation, vision, and touch are updated dynamically to map the specific, local representation of ourselves in space. BSC is closely associated with bottom-up and top-down aspects of consciousness. Recently, virtual- and augmented-reality technology have been used to explore perceptions of BSC. These recent achievements are partly attributed to advances in modern technology, and partly due to the rise of virtual and augmented reality markets. Virtual reality head-mounted displays can alter aspects of perception and consciousness unlike ever …


Attenuated Typicality Effect In Category-Based Inferences: Implications For Autism Spectrum Disorder, Janani Rajagopalan Sep 2023

Attenuated Typicality Effect In Category-Based Inferences: Implications For Autism Spectrum Disorder, Janani Rajagopalan

Dissertations, Theses, and Capstone Projects

Individuals diagnosed with Autism Spectrum Disorder (ASD) often encounter challenges in assimilating atypical exemplars into their categorical prototypes, a cognitive hurdle that can impact their interpretative and integrative capacities. Addressing this problem, the present research sought to develop a robust methodological approach to reduce the effect of this disparity. We examined the elements embedded within the category's internal structure, with the intention of experimentally attenuating the pronounced typicality effect, which is often exaggerated in ASD.

Across four experiments, the thesis investigated the cognitive and neural underpinnings that shape the access to the typicality gradient intrinsic to a category's structure. The …