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Articles 751 - 780 of 1073
Full-Text Articles in Animal Studies
Free-Stall Dimensions: Effects On Preference And Stall Usage, Cassandra B. Tucker, Daniel M. Weary, David Fraser
Free-Stall Dimensions: Effects On Preference And Stall Usage, Cassandra B. Tucker, Daniel M. Weary, David Fraser
Housing and Confinement of Farm Animals Collection
In 2 experiments, free-stall dimensions were examined to determine how they affected stall preference, usage, cleanliness, and milk production in Holstein dairy cattle. In experiment 1, stall width (112 or 132 cm) and stall length (229 and 274 cm from curb to wall) were compared in a 2 × 2 factorial arrangement of stall treatments using 15 individually housed, non-lactating animals. Cows showed no clear preference for stall size as measured by lying time. When animals had no choice between stalls, average lying time was higher in the wide stalls than in the narrow stalls (10.8 vs. 9.6 ± 0.3 …
Reflections On Animal Selves, Marc Bekoff, Paul W. Sherman
Reflections On Animal Selves, Marc Bekoff, Paul W. Sherman
Sentience Collection
Is self-cognizance a uniquely human attribute, or do other animals also have a sense of self? Although there is considerable interest in this question, answers remain elusive. Progress has been stymied by misunderstandings in terminology, a focus on a narrow range of species, and controversies over key concepts, experimental paradigms and interpretations of data. Here, we propose a new conceptual and terminological framework, emphasizing that degrees of self-cognizance differ among animals because of the cognitive demands that their species-specific social structures and life-history characteristics have placed upon them over evolutionary time. We suggest that the self-cognizance of an organism falls …
Differences In Response To Hypoxia In The Three-Spined Stickleback From Lotic And Lentic Localities: Dominance And An Anaerobic Metabolite, L. U. Sneddon, J. Yerbury
Differences In Response To Hypoxia In The Three-Spined Stickleback From Lotic And Lentic Localities: Dominance And An Anaerobic Metabolite, L. U. Sneddon, J. Yerbury
Aquaculture Collection
Dominance hierarchies of the three-spined stickleback Gasterosteus aculeatus from river and pond populations were subjected to hypoxia (20%, range±1%). Under hypoxia, the hierarchies were less stable in terms of rank position and tissue L-lactate was higher in river fish than pond fish under normoxia and hypoxia. Dominant fish gained mass under normoxia but lost mass under hypoxic conditions possibly due to them maintaining high levels of aggression.
Drive Through Arcata Bottom Interview With Ike Moxon (2004), Susie Van Kirk
Drive Through Arcata Bottom Interview With Ike Moxon (2004), Susie Van Kirk
Susie Van Kirk Papers
Ike drove and Susie took notes. We started out by trying to identify the remaining dairies on the Bottom: 1. Cardoza (Masonic Lodge property on Jackson Ranch Road, formerly Richard Moxon's place; 2. John and Jack Mason's on Foster; 3. Louie Ferreira on Lanphere Road; 4. Jose Homem at north end of Seidell Road, old Pontoni place; 5. Collenberg on Mad River Road where road turns to the west; 6. Gomes on Parton Lane near Janes Road and on West End Road; 7. Domingo Santos on Vaissade Road; 8. Nicholson on Mad River Road; 9. unknown on west side of …
Arcata Bottom (2004), Susie Van Kirk
Arcata Bottom (2004), Susie Van Kirk
Susie Van Kirk Papers
Arcata Bottom land management and agricultural records spanning from the 1850s to the 1970s.
Related to "Drive Through Arcata bottom Interview with Ike Moxon" by Susie Van Kirk
Effect Of Pig Weaning Age And Commingling After The Nursery Phase On Humoral And Behavioral Indicators Of Well-Being And On Growth Performance, Sarah C. Arthur, Mari E. Davis, Jason K. Apple, Charles V. Maxwell
Effect Of Pig Weaning Age And Commingling After The Nursery Phase On Humoral And Behavioral Indicators Of Well-Being And On Growth Performance, Sarah C. Arthur, Mari E. Davis, Jason K. Apple, Charles V. Maxwell
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
Two hundred and sixteen pigs were weaned at 14 or 21 d of age to determine the effect of weaning age and commingling after the nursery phase on growth and behavior of pigs in a wean-to-finish facility. Pigs were divided into older and younger age groups and allotted 12 pigs/pen with nine replications of each group. At the end of the nursery phase (d 34 after weaning), one-half of the pigs in each group were removed and commingled for the grower/finisher phase and the other half remained in their original pens. Beginning at weaning (d 0), pigs were monitored via …
Impact Of Dietary Changes On Hepatic Homocysteine Metabolism In Young Broilers, Fauna M. Ganson, Padmakumar Pillai, Jason L. Emmert
Impact Of Dietary Changes On Hepatic Homocysteine Metabolism In Young Broilers, Fauna M. Ganson, Padmakumar Pillai, Jason L. Emmert
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
Information regarding the impact of sulfur amino acids (SAA) on hepatic homocysteine (Hcy) flux through the various metabolic pathways competing for Hcy in young broilers is lacking. An experiment was conducted to evaluate the impact of varying levels of dietary methionine (Met), choline, and betaine on hepatic Hcy flux in young broiler chickens. A standard starter basal diet was fed to chicks until 8 d of age; 12 experimental diets were given from 8-22 d. The experimental basal diet contained deficient levels of Met and cysteine (Cys); supplemental Met (0, 0.08, 0.16, and 0.24%) was added to the basal diet …
Laboratory-Scale Evaluation Of Incandescent And Compact Florescent Lamps For Poultry House Lighting, Leanne Gabriel, Donald M. Johnson
Laboratory-Scale Evaluation Of Incandescent And Compact Florescent Lamps For Poultry House Lighting, Leanne Gabriel, Donald M. Johnson
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
This laboratory-scale study compared 1000- and 2000-h rated 60W incandescent lamps and 6000-h rated 60W-equivalent compact florescent lamps over 6000 h of simulated broiler-house operation. The four original 1000-h incandescent lamps were replaced 22 times and the four 2000-h incandescent lamps were replaced 14 times. None of the four compact florescent lamps failed during the 6000-h experiment, although one was broken due to human error. Both types of incandescent lamps had significantly higher (p < .0001) mean illuminance (lx) than did the compact florescent lamps. The compact florescent lamps used significantly less (p < .0001) power (W) and had significantly higher (p < .0001) efficiency (lx/W) than the incandescent lamps. Despite a higher initial purchase price, the total cost (purchase + replacement + electrical) of operating compact florescent lamps was approximately 36% lower than the total cost of operating either type of incandescent lamp over the 6000 h period. The results of this study indicate that even at a least-cost price for electricity ($0.04/kW/h), growers can reduce total broiler-house lighting costs by replacing incandescent lamps with compact florescent lamps.
Assessment Of Thermal Infrared Detection Rates Using White-Tailed Deer Surrogates, Robert E. Kissell Jr., Philip A. Tappe
Assessment Of Thermal Infrared Detection Rates Using White-Tailed Deer Surrogates, Robert E. Kissell Jr., Philip A. Tappe
Journal of the Arkansas Academy of Science
As thermal infrared imaging technology has improved, it has increasingly been used for estimating sizes of wildlife populations. The greatest bias of thermal infrared surveys is the lack of known detection rates to adjust for visibility bias. As with visual surveys, a measure of detection rate is needed to provide unbiased estimates. We assessed the detection rate of white-tailed deer (Odocoileus virginianus) using a thermal infrared sensor (1.2 - 5.9 /an) from an aerial platform. Similar characteristics between thermal signatures of people and deer allowed us to use people in a reclined or horizontal position as surrogates for deer. We …
Acaricidal Efficacy Of Various Agents In The Treatment Of Naturally Occurring Ornithonyssus Sylviarum (Acari: Macronyssidae) Infestations Of Chickens, Maggie Phillips, T. A. Yazwinski, C. A. Tucker, Jennifer Robins, Jeremy Powell, Linda Stamps
Acaricidal Efficacy Of Various Agents In The Treatment Of Naturally Occurring Ornithonyssus Sylviarum (Acari: Macronyssidae) Infestations Of Chickens, Maggie Phillips, T. A. Yazwinski, C. A. Tucker, Jennifer Robins, Jeremy Powell, Linda Stamps
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
The northern fowl mite (NFM), Ornithonyssus sylviarum, is a commonly occurring external parasite of chickens. Primarily, caged layers have the greatest incidence of this mite, with bird unrest, unthriftiness and lowered production as some of the adverse effects of the infestation. In the current study, birds with natural NFM infestations were randomized into five treatment groups, placed in individual cages in treatment-specific batteries (all in one room), and evaluated for 28 d for infestation quantification by way of index scoring and feather digest. No treatments were 100% effective in eliminating all life stages of the mite. Tetrachlorvinphos in combination with …
A Survey Into The Prevalence Of Parasitic Helminths In Broiler Breeders, Anita Sarathi, Tom Yazwinski, Chris Tucker, Jennifer Robins
A Survey Into The Prevalence Of Parasitic Helminths In Broiler Breeders, Anita Sarathi, Tom Yazwinski, Chris Tucker, Jennifer Robins
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
A survey was conducted to determine the prevalence of helminth infections in spent broiler breeders. Intestinal tracts from 10 birds from each of five farms were obtained and examined for parasite identification and quantification. Heterakis gallinarum infections were the most common, followed in order of decreasing incidence by Capillaria obsignata, Ascaridia galli, and Raillietina cesticillus. Peak worm burdens for individual birds were 121 (A. galli), 535 (H. gallinarum), 215 (C. obsignata) and 125 (R. cesticillus). Significant farm-to-farm variation in worm burdens was observed.
Arkansas Animal Science Department Report 2003, Zelpha B. Johnson, D. Wayne Kellogg
Arkansas Animal Science Department Report 2003, Zelpha B. Johnson, D. Wayne Kellogg
Arkansas Agricultural Experiment Station Research Series
The faculty and staff of the Animal Science Program are pleased to present the sixth edition of the Arkansas Animal Science Report. As with virtually all programs in the country, budget constraints presented serious challenges to teaching, research, and extension programming. However, the faculty and staff responded with innovation, good management, and hard work to maintain a productive program designed to benefit the students of the University and the citizens of the state. We are committed to remaining faithful to our Land-Grant mission. A sincere thank you is owed to Dr. Zelpha Johnson and Dr. Wayne Kellogg for editing this …
Assessing Animal Welfare At The Farm And Group Level: The Interplay Of Science And Values, D. Fraser
Assessing Animal Welfare At The Farm And Group Level: The Interplay Of Science And Values, D. Fraser
Assessment of Animal Welfare Collection
In the social debate about animal welfare we can identify three different views about how animals should be raised and how their welfare should be judged: (1) the view that animals should be raised under conditions that promote good biological functioning in the sense of health, growth and reproduction, (2) the view that animals should be raised in ways that minimise suffering and promote contentment, and (3) the view that animals should be allowed to lead relatively natural lives. When attempting to assess animal welfare, different scientists select different criteria, reflecting one or more of these value-dependent views. Even when …
Novel Object Test: Examining Nociception And Fear In The Rainbow Trout, Lynne U. Sneddon, Victoria A. Braithwaite, Michael J. Gentle
Novel Object Test: Examining Nociception And Fear In The Rainbow Trout, Lynne U. Sneddon, Victoria A. Braithwaite, Michael J. Gentle
Veterinary Science and Medicine Collection
This study aimed to assess fear responses to a novel object while experiencing a noxious event to determine whether nociception or fear will dominate attention in a fish in novel object testing paradigm. This experimentally tractable animal model was used to investigate (1) the degree of neophobia to a novel object while experiencing noxious stimulation, (2) the response of the fish after removing the fear-causing event by using a familiar object, and (3) the effects of removing the nociceptive response by morphine administration and examining the response to a novel object. Control animals displayed a classic fear response to the …
The Evidence For Pain In Fish: The Use Of Morphine As An Analgesic, Lynne U. Sneddon
The Evidence For Pain In Fish: The Use Of Morphine As An Analgesic, Lynne U. Sneddon
Veterinary Science and Medicine Collection
This paper discusses the evidence for pain perception in fish and presents new data on morphine analgesia in fish. Recent anatomical and electrophysiological studies have demonstrated that fish are capable of nociception, the simple detection of a noxious, potentially painful stimulus and the reflex response to this. To prove pain perception, it must be demonstrated that an animal’s behaviour is adversely affected by a potentially painful event and this must not be a reflex response. The present study examined the acute effects of administering a noxious chemical to the lips of rainbow trout (Oncorhynchus mykiss) to assess what changes occurred …
Social Learning Of Prey Location In Hatchery-Reared Atlantic Salmon, C. Brown, A. Markula, K. Laland
Social Learning Of Prey Location In Hatchery-Reared Atlantic Salmon, C. Brown, A. Markula, K. Laland
Aquaculture Collection
Naïve, hatchery-reared Atlantic salmon Salmo salar parr were paired with demonstrators that had been pre-trained to accept live prey from the surface or from the benthos. After 6 days of observing demonstrators through a clear perspex partition the naïve fish’s benthic foraging skills were tested. The results revealed that hatchery-reared Atlantic salmon can be taught to target benthic prey items by observation alone and social learning protocols can be utilized to dramatically increase benthic foraging success. The results are discussed with reference to refining hatchery-rearing practices with a view to improving the post-release survival of hatchery fishes. The role of …
Do Fishes Have Nociceptors? Evidence For The Evolution Of A Vertebrate Sensory System, Lynne U. Sneddon, Victoria A. Braithwaite, Michael J. Gentle
Do Fishes Have Nociceptors? Evidence For The Evolution Of A Vertebrate Sensory System, Lynne U. Sneddon, Victoria A. Braithwaite, Michael J. Gentle
Veterinary Science and Medicine Collection
Nociception is the detection of a noxious tissue-damaging stimulus and is sometimes accompanied by a reflex response such as withdrawal. Pain perception, as distinct from nociception, has been demonstrated in birds and mammals but has not been systematically studied in lower vertebrates. We assessed whether a fish possessed cutaneous nociceptors capable of detecting noxious stimuli and whether its behavior was sufficiently adversely affected by the administration of a noxious stimulus. Electrophysiological recordings from trigeminal nerves identified polymodal nociceptors on the head of the trout with physiological properties similar to those described in higher vertebrates. These receptors responded to mechanical pressure, …
Considering Animals—Not “Higher” Primates, Marc Bekoff
Considering Animals—Not “Higher” Primates, Marc Bekoff
Sentience Collection
In this essay I argue that many nonhuman animal beings are conscious and have some sense of self. Rather than ask whether they are conscious, I adopt an evolutionary perspective and ask why consciousness and a sense of self evolved—what are they good for? Comparative studies of animal cognition, ethological investigations that explore what it is like to be a certain animal, are useful for answering this question. Charles Darwin argued that the differences in cognitive abilities and emotions among animals are differences in degree rather than differences in kind, and his view cautions against the unyielding claim that humans, …
Trigeminal Somatosensory Innervation Of The Head Of A Teleost Fish With Particular Reference To Nociception, Lynne U. Sneddon
Trigeminal Somatosensory Innervation Of The Head Of A Teleost Fish With Particular Reference To Nociception, Lynne U. Sneddon
Veterinary Science and Medicine Collection
Trigeminal somatosensory receptors have not been characterised in teleost fish and studies in elasmobranchs have failed to identify nociceptors. The present study examined the trigeminal nerve of a teleost fish, the rainbow trout (Oncorhynchus mykiss) to determine what types of somatosensory receptors were present on the head of the trout specifically searching for nociceptors. Single unit recordings were made from receptive fields on the head of the fish innervated by the trigeminal nerve. Each receptive field was tested for sensitivity to mechanical, thermal and chemical stimulation. Five different receptor types were found: fast adapting receptors responding to mechanical stimulation; slowly …
Reconstructing Cetacean Brain Evolution Using Computed Tomography, Lori Marino, Mark D. Uhen, Nicholas D. Pyenson, Bruno Frohlich
Reconstructing Cetacean Brain Evolution Using Computed Tomography, Lori Marino, Mark D. Uhen, Nicholas D. Pyenson, Bruno Frohlich
Veterinary Science and Medicine Collection
Until recently, there have been relatively few studies of brain mass and morphology in fossil cetaceans (dolphins, whales, and porpoises) because of difficulty accessing the matrix that fills the endocranial cavity of fossil cetacean skulls. As a result, our knowledge about cetacean brain evolution has been quite limited. By applying the noninvasive technique of computed tomography (CT) to visualize, measure, and reconstruct the endocranial morphology of fossil cetacean skulls, we can gain vastly more information at an unprecedented rate about cetacean brain evolution. Here, we discuss our method and demonstrate it with several examples from our fossil cetacean database. This …
A Simple Reason For A Big Difference: Wolves Do Not Look Back At Humans, But Dogs Do, Ádám Miklósi, Eniko Kubinyi, József Topál, Márta Gácsi, Zsófia Virányi, Vilmos Csányi
A Simple Reason For A Big Difference: Wolves Do Not Look Back At Humans, But Dogs Do, Ádám Miklósi, Eniko Kubinyi, József Topál, Márta Gácsi, Zsófia Virányi, Vilmos Csányi
Communication Skills Collection
The present investigations were undertaken to compare interspecific communicative abilities of dogs and wolves, which were socialized to humans at comparable levels. The first study demonstrated that socialized wolves were able to locate the place of hidden food indicated by the touching and, to some extent, pointing cues provided by the familiar human experimenter, but their performance remained inferior to that of dogs. In the second study, we have found that, after undergoing training to solve a simple manipulation task, dogs that are faced with an insoluble version of the same problem look/gaze at the human, while socialized wolves do …
The Bold And The Shy: Individual Differences In Rainbow Trout, L. U. Sneddon
The Bold And The Shy: Individual Differences In Rainbow Trout, L. U. Sneddon
Aquaculture Collection
Boldness and shyness were investigated as ‘personality’ traits in hatchery-reared rainbow trout Oncorhynchus mykiss. Bold fish spent more time in an open area and were more active than shy fish and these behaviours could be used as indicators of boldness and shyness. These differences were related to learning ability in a simple conditioning task. Bold fish learned the task more quickly than shy fish.
Effects Of Three Types Of Free-Stall Surfaces On Preferences And Stall Usage By Dairy Cows, Cassandra B. Tucker, Daniel M. Weary, David Fraser
Effects Of Three Types Of Free-Stall Surfaces On Preferences And Stall Usage By Dairy Cows, Cassandra B. Tucker, Daniel M. Weary, David Fraser
Housing and Confinement of Farm Animals Collection
One important criterion in choosing appropriate housing systems for dairy cattle is that the freestall provides a comfortable surface for the cow. This paper describes two experiments testing the effects of commonly used lying surfaces on stall preference and stall usage by Holstein cows. In both experiments, 12 cows were housed individually in separate pens. Each pen contained three free stalls with a different surface: deep-bedded sawdust, deep-bedded sand, and a geotextile mattress covered with 2 to 3 cm of sawdust. The animals were restricted to each surface in turn, in a random order for either 2 (Experiment 1) or …
Farm Disease Crises In The United Kingdom: Lessons To Be Learned, Michael C. Appleby
Farm Disease Crises In The United Kingdom: Lessons To Be Learned, Michael C. Appleby
State of the Animals 2003
Over the last fifteen years, a diverse succession of disease-related crises has befallen farm animal and food industries in the United Kingdom. Some have involved animal health, with little risk to humans. Some have involved human health, with animals acting as a reservoir for infection but little affected themselves. Some, however— including the most alarming— have involved both animal and human health through zoonoses, diseases transmittable from animal to human. All of these crises are linked in the public mind and in many commentaries, and indeed there are issues that many of them share. The most common of these is …
The Effects Of Classic And Variant Infectious Bursal Disease Viruses On Lymphocyte Populations In Specific-Pathogen-Free White Leghorn Chickens, Christina L. Johnson, Ashley K. Cox, April D. Keeter, Will J. Quinn, Gisela F. Erf, Lisa A. Newberry
The Effects Of Classic And Variant Infectious Bursal Disease Viruses On Lymphocyte Populations In Specific-Pathogen-Free White Leghorn Chickens, Christina L. Johnson, Ashley K. Cox, April D. Keeter, Will J. Quinn, Gisela F. Erf, Lisa A. Newberry
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
Infectious bursal disease virus (IBDV) is a pathogen that primarily infects B lymphocytes in domestic avian species. This viral infection has been associated with immunosuppression, clinical disease/mortality, and enteric malabsorption effects. The purpose of this experiment was to compare the effects of a classic (USDA-STC) and a new variant IBDV (RB-4, known to induce primarily the enteric disease) on immune cell populations in lymphoid organs. Seventeen-day-old specific-pathogen-free (SPF) White Leghorn chickens were either not infected (control) or inoculated with either USDA-STC or RB-4 IBD viral isolate. On days 3 and 5 post-inoculation (PI), lymphoid tissues were collected to prepare cell …
Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles—E,E+, And Erh, Rupali Ugrankar, Kim Cheng, Ronald Okimoto
Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles—E,E+, And Erh, Rupali Ugrankar, Kim Cheng, Ronald Okimoto
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
The melanocortin 1-receptor (MC1-R) gene plays a key role in the expression of fur and feather color in mammals and birds by regulating the distribution of two melanin pigments: eumelanin (black/brown) and pheomelanin (red/yellow). MC1-R corresponds to the classical Extension (E) locus in mice, pigs, dogs, horses, and chickens. Three E locus alleles, the wild-type (e+), brown (E), and redhead (erh) have been identified in Japanese quail (Coturnix japonica). To determine if the quail E locus phenotypes were due to variation in the MC1-R gene, the coding region of the MC1-R gene was PCR amplified and DNA sequenced using genomic …
Phase-Feeding Affects Crude Protein Intake, Excretion, And Retention Of Broilers From 21 To 63 Days, Niki Loupe, Trey Pope, Padmakumar Pillai, Jason Emmert
Phase-Feeding Affects Crude Protein Intake, Excretion, And Retention Of Broilers From 21 To 63 Days, Niki Loupe, Trey Pope, Padmakumar Pillai, Jason Emmert
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
An experiment was conducted to assess effects of phase-feeding (PF) on crude protein (CP) intake, excretion, and retention of broilers. Six birds were housed individually and were fed diets formulated using recommendations from National Research Council (NRC) or linear regression equations. Two PF treatments were prepared: standard (PF) and low (PF10), in which predicted lysine, sulfur amino acids, and threonine recommendations were reduced by 10%. For PF and PF10, two diets (high-nutrient and low-nutrient density) were blended in variable quantities to produce rations matching predicted amino acid requirements over two intervals. Birds were fed a single NRC grower and finisher …
Description Of A Poorly Differentiated Carcinoma Within The Brainstem Of A White Whale (Delphinapterus Leucas) From Magnetic Resonance Images And Histological Analysis, Sam H. Ridgway, Lori Marino, T. P. Lipscomb
Description Of A Poorly Differentiated Carcinoma Within The Brainstem Of A White Whale (Delphinapterus Leucas) From Magnetic Resonance Images And Histological Analysis, Sam H. Ridgway, Lori Marino, T. P. Lipscomb
Veterinary Science and Medicine Collection
In this study we used magnetic resonance imaging (MRI) to investigate neuroanatomical structure in the brain of a white whale (Delphinapterus leucas) that died from a large tumor within the brainstem. This specimen was also compared with a normal white whale brain using MRI. MRI scans of the white whale specimen show how the tumor deformed surrounding brain structure. Histopathological analysis indicated a poorly differentiated carcinoma of uncertain origin. These analyses demonstrate the usefulness of supplementing histological analyses of pathology with studies of gross morphology facilitated by MRI.
Arkansas Animal Science Department Report 2002, Zelpha B. Johnson, D. Wayne Kellogg
Arkansas Animal Science Department Report 2002, Zelpha B. Johnson, D. Wayne Kellogg
Arkansas Agricultural Experiment Station Research Series
No abstract provided.
Endogenous Gonadal Hormone Exposure And Bone Sarcoma Risk, Dawn M. Cooley, Benjamin C. Beranek, Deborah L. Schlittler, Nita W. Glickman, Lawrence T. Glickman, David J. Waters
Endogenous Gonadal Hormone Exposure And Bone Sarcoma Risk, Dawn M. Cooley, Benjamin C. Beranek, Deborah L. Schlittler, Nita W. Glickman, Lawrence T. Glickman, David J. Waters
Endocrinology Collection
Although experimental and clinical evidence suggest that endogenous sex hormones influence bone sarcoma genesis, the hypothesis has not been adequately tested in an appropriate animal model. We conducted a historical cohort study of Rottweiler dogs because they frequently undergo elective gonadectomy and spontaneously develop appendicular bone sarcomas, which mimic the biological behavior of the osteosarcomas that affect children and adolescents. Data were collected by questionnaire from owners of 683 Rottweiler dogs living in North America. To determine whether there was an association between endogenous sex hormones and risk of bone sarcoma, relative risk (RR) of incidence rates and hazard ratios …