Social and Behavioral Sciences Commons^™

Effects Of Corticosterone And Ethanol Co-Exposure On Hippocampal Toxicity: Potential Role For The Nmda Nr2b Subunit, Tracy Renee Butler

University of Kentucky Doctoral Dissertations

Chronic ethanol (EtOH) exposure produces neuroadaptations within the NMDA receptor system and alterations in HPA axis functioning that contribute to neurodegeneration during ethanol withdrawal (EWD). Chronic EtOH exposure and EWD, as well as corticosteroids, also promote increased synthesis and release of polyamines, which allosterically potentiate NMDA receptor open-channel time at the NR2B subunit. The current studies investigated effects of 10 day EtOH and corticosterone (CORT) co-exposure on toxicity during EWD in rat organotypic hippocampal slice cultures, and alterations in function and/or density of the NR2B subunit of the NMDA receptor that may mediate CORT-potentiation of toxicity during EWD. We hypothesized …

Generational Influences On Educational Perceptions Of Rural African Americans, Quentin Romar Tyler

University of Kentucky Doctoral Dissertations

This study discussed research exploring intergenerational influences on the educational experiences and expectations of rural African Americans in Hopkinsville, Kentucky. Hopkinsville is located in a district that has lagged behind reaching state and national benchmarks in educational attainment. It is home to one of the largest African American communities in the state and reflects striking disparities in educational achievement by race as it struggles to close achievement gaps generally. Through qualitative case study, this study found that both college track sons and parents shared comparable views on education while low performing parents and sons did not have the same views. …

Structures, Roles And Relationships Within Public Health’S Response To The 2009-2010 H1n1 Outbreak: The Ties That Bind Public Information Officers And Emergency Risk Communication Efforts, Kathleen G. Vidoloff

University of Kentucky Doctoral Dissertations

Little is known about the role of public health public information officers (PIOs) during public health emergencies. This study uses interpretative methods to learn about the organizational structures that facilitate and constrain emergency risk communication efforts during public health emergencies. Interpretive thematic comparative analysis of PIOs experiences and reflections about their involvement in the 2009-2010 H1N1 response will be used to illustrate how social interactions between and among PIOs, public health staff, and representatives from other agencies create implicit and explicit structures that facilitate and constrain emergency risk communication. The application of three specific concepts from structuration theory, namely, agent, …

Mississippi Period Occupational And Political History Of The Middle Savannah River Valley, Keith Stephenson

University of Kentucky Doctoral Dissertations

Research focusing on the political economy of Mississippian mound centers in the middle Savannah River valley has prompted a reevaluation of current interpretations regarding societal complexity. I conclude the clearest expression of classic Mississippian riverine-adaptation is evident at centers immediately below the Fall Line with their political ties to chiefdom centers in the Piedmont, and especially Etowah. By contrast, those centers on the interior Coastal Plain were politically autonomous with minimal signatures in social ranking. The scale of appropriated labor and resulting level of surplus production, necessitated by upland settlement on the Aiken Plateau, fostered social contradictions making communally-oriented and …

Pollution Knowledge And Urban Water Politics In The Ganges River Basin (India), Sya Buryn Kedzior

University of Kentucky Doctoral Dissertations

Millions of people rely upon the Ganges River as a source of water provision and a site of disposal for sewage, solid waste, agricultural runoff and industrial effluent. The river is also a goddess in the Hindu pantheon who is worshipped for her purificatory powers, despite water quality levels that fall far short of standards for use in bathing, washing, and drinking. In recent years, a number of non-governmental organizations (NGOs) have formed to oppose both pollution of the river and the failure of state-run pollution abatement programs. They are joined by an increasingly frequent number of seemingly spontaneous protests …

Boundaries And Breaches: Complexities And Strategies Down On The Farm, Debra S. Kershaw

University of Kentucky Doctoral Dissertations

Employing a wide range of theoretical and methodological tools, practitioners within an array of disciplines have attempted to gain new understanding about the structural changes in the agricultural system in the United States and around the world. From Agricultural Economists to Sociologists, quantitative and qualitative research has attempted to shed light on structural change in agriculture and its implications for the real lives of farmers, their families, and consumers of their goods. The current research adopts a comparative-historical approach to examining the particular affects of structural change in six counties in central Nebraska. The general theoretical frame on which this …

The Effects Of Minimum Salaries On Firm Tenure, Career Length, And The Experience Distribution: Evidence From The National Football League, Johnny C. Ducking

University of Kentucky Doctoral Dissertations

I use data from the National Football League (NFL) to analyze the impact of minimum salaries on an employee’s firm tenure, an employee’s career length, and an employer’s distribution of employee experience. The NFL has a salary structure in which the minimum salary a player can receive increases with the player’s years of experience. Salary schedules similar to the NFL’s exist in public education, Secret Service, Internal Revenue Service, other federal government agencies, the Episcopalian church, and unionized industries. Even though the magnitude of the salaries in the NFL differs from other industries, this study provides insight to the impact …

Three Essays Evaluating Choices Of Teachers And Administrators In Kentucky Public Schools, Nathan Barrett

University of Kentucky Doctoral Dissertations

Public K-12 education is a large enterprise in the United States. Through local, state and federal sources, the U.S. allocated over $610 billion to K-12 public education in 2009 (NCES). Not only is the commitment of public funds for education substantial, the provision of K-12 education is primarily administered by the government in non-market settings through local school districts. It is this institutional environment that generates the impetus for evaluating how those in education make choices in the absence of markets.

Like traditional markets, non-market solutions often fail because the incentives facing individuals and agencies elicit choices which produce outcomes …

Lavapiés, Madrid As Twenty-First Century Urban Spectacle, Matthew Isaiah Feinberg

University of Kentucky Doctoral Dissertations

Informed by the theories of Henri Lefebvre regarding the production of space and the theories of scale found in current scholarship in Cultural Geography, my methodology analyzes both dramatic texts and theater spaces to investigate how cultural production and capital converge in the “spectacle” of urban space. While employing this term “spectacle” to describe how dramatic texts, theater productions, and modern architecture transform the urban landscape into a metaphoric theater space for the production of local, national, and global identities, this project examines the relationship between theater and urban change in Lavapiés, an iconic, multicultural, and oftenunderserved neighborhood located in …

Conformation Dependent Monoclonal Antibodies Distinguish Different Replicating Strains Or Conformers Of Prefibrillar Aβ Oligomers, Rakez Kayed, Isabel Canto, Leonid Breydo, Suhail Rasool, Tamas Lukacsovich, Jessica Wu, Ricardo Albay, Anna Pensalfini, Stephen Yeung, Elizabeth Head, J. Lawrence Marsh, Charles Glabe

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary pathological species of protein aggregates.

RESULTS: We have produced several monoclonal antibodies that specifically recognize prefibrillar oligomers and do not recognize amyloid fibrils, monomer or natively folded proteins. Like the polyclonal antisera, the individual monoclonals recognize generic epitopes that do not depend on a specific linear amino acid sequence, but they display distinct preferences for different subsets of prefibrillar oligomers. Immunological …

Archivists’ Toolkit Collaboration, Kathryn Lybarger

Library Presentations

No abstract provided.

Criminal Offending Among Respondents To Protective Orders: Crime Types And Patterns That Predict Victim Risk, Carol E. Jordan, Adam J. Pritchard, Danielle Duckett, Richard Charnigo

Office for Policy Studies on Violence Against Women Publications

Research has shown that respondents to protective orders have robust criminal histories and that criminal offending behavior often follows issuance of a protective order. Nonetheless, the specific nature of the association between protective orders and criminal offending remains unclear. This study uses two classes of statistical models to more clearly delineate that relationship. The models reveal factors and characteristics that appear to be associated with offending and protective order issuance and provide indications about when a victim is most at risk and when the justice system should be most ready to provide immediate protection.

A Model Of The Information Seeking And Decision Making Of Online Coin Buyers, Donald O. Case

Information Science Faculty Publications

Introduction. The Everyday Life Information Seeking approach suggests that much information behaviour takes place in non-work settings, for example in the pursuit of leisure activities such as hobbies. This study focuses on a community of collectors to examine how they gather information to decide whether to purchase an item for their collection when the target item has an ambiguous or deficient description.

Method. Manual scanning of eBay and other online discussion board for coin buyers led to 187 postings indicating an attempt to reach a purchase decision, or to authenticate a purchased coin, through solicitation or posting of advice.

Analysis. …

Networks Of European Cities In Worlds Of Global Economic And Environmental Change, Stanley D. Brunn, Lomme Devriendt, Andrew Boulton, Ben Derudder, Frank Witlox

Geography Faculty Publications

Geographers have a long tradition of classifying cities using a number of criteria. Population size, industrial production, capital city functions, airline connections, sites of sporting events and major headquarters and banks are among them. While these studies are useful in looking at cities in an economy and population at a given point of time, they are less useful in assessing rapidly occurring changes within a regional or global system. Our research represents a new approach to classify cities and urban systems; we use the volume and networks/linkages or flows associated with electronic Information or “Knowledge worlds.” We argue that in …

Saving Student Brian: Engaging Students With Innovative Technology, Stacey Greenwell, Beth Kraemer, Debbie Sharp, Susan K. Smith

Library Faculty and Staff Publications

Question: How do you provide library orientation for a large number of first-year students without boring them to death? Answer: Create a video using new technology, student actors, and a little fun.

Learn step by step how the University of Kentucky Libraries revived their first year student orientation experience creating a video filmed on campus and in the virtual world, Second Life. From writing and filming to editing and screening, the presenters will discuss the process, offering practical tips and suggestions for creating your own instructional video. In addition, the presenters will discuss lessons learned from this experience.

The Us Preventive Service Taskforce And The Guide To Clinical Preventive Services., F. Douglas Scutchfield Md

Preventive Medicine and Environmental Health Presentations

No abstract provided.

Community Health Assesments, F. Douglas Scutchfield Md

Preventive Medicine and Environmental Health Presentations

No abstract provided.

Caveat Emptor: It May Be Electronic, But Don’T Overlook The Fine Print, Stephanie N. Aken

Library Presentations

No abstract provided.

Public Health Services And Systems Research: Data For Research, F. Douglas Scutchfield Md

Preventive Medicine and Environmental Health Presentations

No abstract provided.

Southeastern Law Librarian Fall 2010, Seaall

Newsletters

No abstract provided.

Managing Faculty And Student Expectations At The Circulation Desk, Jennifer A. Bartlett

Library Presentations

Work at main circulation desks in large academic and public libraries involves the ability to manage increasing service demands from patrons, colleagues, and the organization's administration. The perception of circulation as a catch-all department, handling responsibilities that do not fit neatly into other areas, can make this work feel like "emptying the litter pan." This presentation discusses the importance of circulation as the professional face of the library and its centrality to effective and efficient library service in the face of challenges involving mission, perception, and funding.

The Appalachian Regional Development Act And Economic Change, James P. Ziliak

University of Kentucky Center for Poverty Research Discussion Paper Series

The Appalachian Regional Development Act of 1965 is one of the longest serving place-based regional development programs in the U.S., and is the largest in terms of geographic scope. I use county-level data from the 1960 thru 2000 Decennial Censuses to evaluate the effect of ARDA on poverty rates and real per capita incomes in Appalachia. The intent to treat parameter is identified in a difference-in-difference-in-difference framework by comparing outcomes in Appalachia to her border counties. Additional knowledge of which counties were solely eligible for highway development funds under ARDA from those counties eligible for both highway as well as …

Deficient Liver Biosynthesis Of Docosahexaenoic Acid Correlates With Cognitive Impairment In Alzheimer's Disease, Giuseppe Astarita, Kwang-Mook Jung, Nicole C. Berchtold, Vinh Q. Nguyen, Daniel L. Gillen, Elizabeth Head, Carl W. Cotman, Daniele Piomelli

Sanders-Brown Center on Aging Faculty Publications

Reduced brain levels of docosahexaenoic acid (C22:6n-3), a neurotrophic and neuroprotective fatty acid, may contribute to cognitive decline in Alzheimer's disease. Here, we investigated whether the liver enzyme system that provides docosahexaenoic acid to the brain is dysfunctional in this disease. Docosahexaenoic acid levels were reduced in temporal cortex, mid-frontal cortex and cerebellum of subjects with Alzheimer's disease, compared to control subjects (P = 0.007). Mini Mental State Examination (MMSE) scores positively correlated with docosahexaenoic/α-linolenic ratios in temporal cortex (P = 0.005) and mid-frontal cortex (P = 0.018), but not cerebellum. Similarly, liver docosahexaenoic acid content was lower in Alzheimer's …

Does Race Based Redistricting Matter For Policy?, Ebonya Washington

University of Kentucky Center for Poverty Research Discussion Paper Series

During the 1990 congressional redistricting many states were mandated to create additional majority minority-resident districts in order to elect more minorities to Congress. Civil rights groups and Republicans cheered. The Party views Democratic districts stripped of Black voters as opportunities to repaint blue districts red. The academic literature agrees, attributing the Republican return to House control in 1994 to race based redistricting. However, this literature generally focuses on the district as the unit of analysis, a focus that is too narrow, as some districts gain Black residents while others lose them. I focus on states, the level at which redistricting …

Poverty, Inequality And Cost Of Living Differences, Enrico Moretti

University of Kentucky Center for Poverty Research Discussion Paper Series

Metropolitan areas in the US are characterized by enormous differences in average income, earnings, and factor productivity. The income of individuals located in metropolitan areas at the top of the income distribution is more than double the income of observationally similar individuals located in metropolitan areas at the bottom of the distribution. These differences reflect, at least in part, variation in local productivity.

Hosted/Hybrid: The Uk-Iarhives Production Model, Kopana Terry

Library Presentations

No abstract provided.

Southeastern Law Librarian Summer 2010, Seaall

Newsletters

No abstract provided.

Iaald 2.0: Integrating Social Networking Into A Traditional Professional Organization, Antoinette Paris Greider

Library Presentations

No abstract provided.

Relationship And Injury Trends In The Homicide Of Women Across The Lifespan: A Research Note, Carol E. Jordan, Adam J. Pritchard, Danielle Duckett, Pamela Wilcox, Tracey Corey, Mandy Combest

Office for Policy Studies on Violence Against Women Publications

In 2006, more than 3,600 women in the United States lost their lives to homicide. Descriptive data regarding homicides of women are beginning to reveal important complexities regarding victim–offender relationships, severity of injury, and age of female homicide victim. More specifically, there is some indication that the correlation between victim–offender relationship and injury severity may be conditional, depending on victim age. This retrospective review accessed medical examiner records of female homicide victims from 2002 through 2004, and its findings offer additional illumination on the trends in associations of injury and relationship variables in the homicide of women over their life …

Batch Editing Marc Records With Marcedit And Regular Expressions, Kathryn Lybarger, Julene L. Jones

Library Presentations

No abstract provided.