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Articles 61 - 90 of 5729

Full-Text Articles in Social and Behavioral Sciences

Bridging Theory And Self-Development In Human Services And Counselor Education, Kristy Carlisle Jan 2026

Bridging Theory And Self-Development In Human Services And Counselor Education, Kristy Carlisle

Journal of Human Services Scholarship and Interprofessional Collaboration

Counselor and human services education increasingly recognize self-awareness as a core component of professional competence and ethical practice. This conceptual manuscript presents a pedagogical framework that integrates major helping theories as tools for structured self-reflection and self-development among students and practitioners. Drawing from experiential learning theory, reflective practice, and models of counselor identity formation, the approach encourages learners to view themselves through theoretical lenses such as person-centered, cognitive-behavioral, and existential frameworks, paralleling the very lenses through which they will view their clients in practice. By engaging in guided reflective activities, students examine personal beliefs, emotions, and behaviors to enhance self-understanding, …


Threads Of Empathy: An Integrative Model Of Empathy In The Schools, Arthur J. Clark, Tara M. Simpson Jan 2026

Threads Of Empathy: An Integrative Model Of Empathy In The Schools, Arthur J. Clark, Tara M. Simpson

Journal of Human Services Scholarship and Interprofessional Collaboration

Empathy has a distinctive and evolving history in education for cultivating human relationships and engendering mutual understanding. Within a school setting, empathic engagement is essential for the social and emotional development of children and adolescents. From an educational perspective, literature from multiple disciplines and specialties illustrate innovative practices to harness empathy in the classroom and beyond. The representative initiatives hold promise for developing an integrative model of empathy within a school or a school district through a program involving interprofessional collaboration.


Integrating Clinical Reasoning Into Mental Health Diagnosis: A Conceptual Framework For Counseling Practice, Ashley F. Waddington, Alexander M. Fields, Haley Ault Jan 2026

Integrating Clinical Reasoning Into Mental Health Diagnosis: A Conceptual Framework For Counseling Practice, Ashley F. Waddington, Alexander M. Fields, Haley Ault

Journal of Human Services Scholarship and Interprofessional Collaboration

Clinical reasoning has long guided diagnostic accuracy in nursing and medical fields, but its application in mental health counseling remains limited. This paper presents a conceptual diagnostic decision-making (DDM) process to embed clinical reasoning into the diagnostic process for counselors, incorporating two vital constructs: counselor self-efficacy and counselor bias (implicit and explicit). Grounded in Bandura’s theory of self-efficacy (1977) and Carvalho et al.’s (2017) clinical reasoning model, the framework highlights the cognitive, behavioral, and contextual factors that shape diagnostic decision-making in early-career counselors, including counselor biases. The paper calls for reform in counselor training, emphasizing curriculum enhancements as pathways to …


The State Of Interprofessional Practice Between Behavior Analysts And Speech-Language Pathologists, Sara Snyder, Heartley Huber, Danika Pfeiffer, Dannette Murray Jan 2026

The State Of Interprofessional Practice Between Behavior Analysts And Speech-Language Pathologists, Sara Snyder, Heartley Huber, Danika Pfeiffer, Dannette Murray

Speech-Language Pathology Faculty Publications

Interprofessional practice (IPP) is necessary to ensure assessment and interventions are designed and implemented both efficiently and effectively. We sought to investigate how Board Certified Behavior Analysts (BCBAs) and Speech-Language Pathologists (SLPs) engage in IPP. Both professionals may provide evaluations and interventions related to communication in schools and community-based healthcare systems. We disseminated a survey to BCBAs and SLPs to elicit information about their collaboration with each other. Topics included: (a) frequency of collaboration and communication with the other professional; (b) confidence engaging in IPP; (c) interprofessional training experiences; (d) barriers and facilitators to collaboration with the other profession; and …


The Emerging Social Media Water Cooler? Motivations For Reddit Use In A Niche League, Jan Boehmer, Brendan O'Hallarn Jan 2026

The Emerging Social Media Water Cooler? Motivations For Reddit Use In A Niche League, Jan Boehmer, Brendan O'Hallarn

Communication & Theatre Arts Faculty Publications

Social media play a key role in sport marketing—with athletes, teams, and leagues directly engaging with their audiences. While Facebook, Instagram, and Twitter have received much attention in the sport marketing and communication literature, research on Reddit is scant. This is particularly noteworthy, as the platform is growing rapidly and promises utility for users with nonmainstream interests to find and engage with each other. This study employs a uses and gratifications approach to investigate how prevalent Reddit use is among fans of the United Football League (UFL), what motivates users to engage with the platform, and whether Reddit use leads …


Grant-O-Thon: A Designathon-Informed Grant Writing Program To Enhance Research Grant Writing Skills In Low- And Middle-Income Countries, Yusha Tao, Gifty Marley, Lauren Fidelak, Bin Yu, Yusuf Babatunde, Anita N. Walker, Anthony A. Attama, Andrea L. Conroy, Esther K. Afolabi, Dimitrios N. Vatakis, Iheanyi Omezuruike Okonko, Shyngle K. Balogun, Hongyun Fu, Xin Peng, Ijeoma M. Ifeorah, Patience Kukundakwe, Alexandra Cossio, Ifeoma M. Obionu, Ángela Patricia Beltrán López, Matthew Idowu Olatubi, Ucheoma C. Nwaozuru, Yuanyi Chen, Huachun Zou, Eneyi E. Kpokiri, Daniil Wu, Oliver Ezechi, Juliet Iwelunmor, Meredith Labarda, Jason J. Ong, Weiming Tang, Joseph D. Tucker Jan 2026

Grant-O-Thon: A Designathon-Informed Grant Writing Program To Enhance Research Grant Writing Skills In Low- And Middle-Income Countries, Yusha Tao, Gifty Marley, Lauren Fidelak, Bin Yu, Yusuf Babatunde, Anita N. Walker, Anthony A. Attama, Andrea L. Conroy, Esther K. Afolabi, Dimitrios N. Vatakis, Iheanyi Omezuruike Okonko, Shyngle K. Balogun, Hongyun Fu, Xin Peng, Ijeoma M. Ifeorah, Patience Kukundakwe, Alexandra Cossio, Ifeoma M. Obionu, Ángela Patricia Beltrán López, Matthew Idowu Olatubi, Ucheoma C. Nwaozuru, Yuanyi Chen, Huachun Zou, Eneyi E. Kpokiri, Daniil Wu, Oliver Ezechi, Juliet Iwelunmor, Meredith Labarda, Jason J. Ong, Weiming Tang, Joseph D. Tucker

Department of Pediatrics Faculty Publications

Problem

Early career researchers in low- and middle-income countries (LMICs) face substantial barriers when writing research grants and have limited writing support. A designathon approach was applied to organize a grant writing workshop (grant-o-thon) tailored for early-career LMIC researchers. This study describes the planning, implementation, and participant-reported outcomes of the grant-o-thon as a participatory training approach.

Approach

Grant-o-thons were organized in 2023, 2024, and 2025. Consistent with the designathon model, the grant-o-thon was structured in three stages: preparation using co-creation with end-users, intensive collaborative teamwork supported by mentor feedback and weekly writing deliverables, and structured follow-up. Each grant-o-thon consisted of …


Causal Effect Estimates Of Online E-Cigarette Marketing Exposure On Future E-Cigarette Harm Perception And Use, Paul T. Harrell, Nicholas T. Williams, Kara E. Rudolph, Rachel Ayala Guzman, Ateeqa Ijaz, Nicole Rychagov, Aaron Null, Silvia S. Martins Jan 2026

Causal Effect Estimates Of Online E-Cigarette Marketing Exposure On Future E-Cigarette Harm Perception And Use, Paul T. Harrell, Nicholas T. Williams, Kara E. Rudolph, Rachel Ayala Guzman, Ateeqa Ijaz, Nicole Rychagov, Aaron Null, Silvia S. Martins

Department of Pediatrics Faculty Publications

Background

Globally, over 10 million youth use e-cigarettes; United States use, in particular, dramatically rose in the late 2010's, exceeding year-over-year increases from any other substance in over four decades. This rise has been partially attributed to youth online e-cigarette marketing exposure, but has not been appropriately studied.

Methods

We examined youth data from the Population Assessment of Tobacco and Health (PATH) spanning the dramatic increase period (Waves 4, 4.5, and 5; 2016-2019). We estimated average risk differences (RD) for Wave 5 e-cigarette harmfulness perception and use comparing all youth versus no youth reporting past-month online e-cigarette marketing exposure in …


Board Attributes, Firm Performance, And The Moderating Role Of National Culture: A Meta-Analysis, Matthew Farrell, Chris H. Willis, Nathapon Siangchokyoo, Ryan L. Klinger, Jamil Kreugel, Hami Usta, Timiry R. Tian, Ying Thaviphoke, Samuel Wilson Jan 2026

Board Attributes, Firm Performance, And The Moderating Role Of National Culture: A Meta-Analysis, Matthew Farrell, Chris H. Willis, Nathapon Siangchokyoo, Ryan L. Klinger, Jamil Kreugel, Hami Usta, Timiry R. Tian, Ying Thaviphoke, Samuel Wilson

Management Faculty Publications

Research Question/Issue

The impact of board structures on firm performance remains a contentious governance topic with competing theoretical paradigms and inconclusive empirical support. Scholars propose that national culture could reconcile contradictory evidence; yet, argumentation is fragmented and direct tests are rare. We meta‐analyzed 513 samples across 54 countries to examine relationships between board structures (i.e., board size, board independence, and CEO duality) and firm performance. We model national culture, using Hofstede's six cultural dimensions, as moderators to test whether these relationships align with agency or stewardship theory across different cultural settings.

Research findings/insights

Findings indicate a substantial moderating role of …


Counseling Professionals' Perspectives On Ai Integration In Education And Supervision: A Concept Mapping Study, Hank Crofford, Elif Bor, Gülşah Kemer Jan 2026

Counseling Professionals' Perspectives On Ai Integration In Education And Supervision: A Concept Mapping Study, Hank Crofford, Elif Bor, Gülşah Kemer

Counseling & Human Services Faculty Publications

The rapid emergence of artificial intelligence (AI) has raised important questions about how new technologies will shape professional norms and practices in counseling. The purpose of this study was to understand how counseling professionals expect AI to be integrated into counselor education and supervision (CES). Using a mixed‐methods concept mapping design, 31 participants generated and sorted statements about the potential roles, benefits, and concerns associated with AI in the profession. Participants represented diverse counseling roles, including counselor educators, licensed professional counselors, supervisors, master's‐ and doctoral‐level trainees, and other counseling‐related professionals. Standard concept mapping procedures were conducted using R, resulting in …


Legislative Debate-Attributed Suicidality Among Lgbtq+ Adults: The Buffering Effect Of Community Belongingness, Keith J. Watts, Shawndaya S. Thrasher, Laneshia R. Conner, Nicole Campbell, Louis G. Baser, Dekeitra Griffin, Sydney P. Howard, Missy Spears, Justin X. Moore Jan 2026

Legislative Debate-Attributed Suicidality Among Lgbtq+ Adults: The Buffering Effect Of Community Belongingness, Keith J. Watts, Shawndaya S. Thrasher, Laneshia R. Conner, Nicole Campbell, Louis G. Baser, Dekeitra Griffin, Sydney P. Howard, Missy Spears, Justin X. Moore

Counseling & Human Services Faculty Publications

Background: In recent years, the sociopolitical landscape in the United States has shifted due to an increase in state-level legislation regarding LGBTQ+ rights, a trend that has been particularly pronounced in the Commonwealth of Kentucky. While the mental health impacts of enacted laws are increasingly documented, a critical gap remains in understanding the psychological toll of the legislative debates themselves—the prolonged periods of public discourse surrounding the restriction of rights. Methods: Utilizing data from the 2025 Queer Kentucky Survey (N = 817), this exploratory study examined the association between LGBTQ+ community belongingness and acute suicidality attributed specifically to anti-LGBTQ+ legislative …


Editorial For Issue 20(1), Jeff Moe, Peighton Corley, Aaron Albright Jan 2026

Editorial For Issue 20(1), Jeff Moe, Peighton Corley, Aaron Albright

Counseling & Human Services Faculty Publications

[Introduction] Hello and welcome to the community of counselors, advocates, and scholars who read the Journal of LGBTQ Issues in Counseling. In our era of continued political attacks and undermining of gender diverse and sexual orientation diverse people, our editorial board remains committed to creating knowledge that speaks to the inherent worth of LGBTQIQA+ people and related groups. Our histories and communities are dynamic, and we continue to shape standards of care and best practice that not only improve the mental health and well-being of gender diverse and sexual orientation diverse people but help improve the lives of all people …


Broaching The Intersectionality Of Race And Disability In School Counseling, Aaron Albright, Emily Goodman-Scott, Jenna Alvarez, Rawn Boulden Jan 2026

Broaching The Intersectionality Of Race And Disability In School Counseling, Aaron Albright, Emily Goodman-Scott, Jenna Alvarez, Rawn Boulden

Counseling & Human Services Faculty Publications

Students of color with disabilities experience compounded inequities. This conceptual article details these compounded inequities. The authors provide a review of the literature related to inequities in education, culturally affirming antiracist school counseling, intersectionality, and broaching. Next, the authors provide a rationale for implementing Day-Vines and colleagues’ multidimensional model of broaching behaviors (MMBB) in school counseling with students of color with disabilities. Then, the authors use the MMBB heuristic to conceptualize practical guidelines for school counselors to engage in direct broaching with their students. These guidelines are tabulated with a description of the four broaching dimensions and their aim within …


Counseling And The Neurodiversity Paradigm: A Call To Action, Emily Goodman-Scott, Rawn Boulden, Aaron Albright, Jenna Alvarez, Betsy M. Perez Jan 2026

Counseling And The Neurodiversity Paradigm: A Call To Action, Emily Goodman-Scott, Rawn Boulden, Aaron Albright, Jenna Alvarez, Betsy M. Perez

Counseling & Human Services Faculty Publications

The counseling profession is rooted in prevention, wellness, mental health, and a critical social justice approach to serving historically marginalized communities, including people with disabilities. The overarching construct of disability comprises subtypes, such as neurodivergence. Given the prevalence of neurodivergent individuals worldwide (approximately 15%-20%), the counseling profession must be prepared to support this community. At the same time, there is a dearth of peer-reviewed literature on neurodiversity specifically for the counseling profession. In this article, we address a timely topic in the profession. We discuss utilizing a critical counseling lens and centering marginalized identities, such as people with disabilities; prominent …


Editorial For Issue 20(2), Jeff Moe, Peighton Corley, Aaron Albright Jan 2026

Editorial For Issue 20(2), Jeff Moe, Peighton Corley, Aaron Albright

Counseling & Human Services Faculty Publications

[Introduction] Hello to the readers of the Journal of LGBTQ Issues in Counseling. Like many counselors, counselors-in-training, scholars, and other individuals you may be coming to the journal looking for insights into your counseling work. Along with publishing original research that creates space for exploring LGBTQ+ lifeways from an open and affirmative perspective, the manuscripts published in the journal have always been grounded in application.


Contemporary Approaches To Group Psychotherapy Supervision, Michelle A. Collins-Greene (Ed.), Molyn Leszcz, Nina W. Brown, Ellen Wright, Scott Giacomucci, Les R. Greene, Susan P. Gantt, Leah M. Niehaus, Francis Kaklauskas, Tony L. Sheppard Jan 2026

Contemporary Approaches To Group Psychotherapy Supervision, Michelle A. Collins-Greene (Ed.), Molyn Leszcz, Nina W. Brown, Ellen Wright, Scott Giacomucci, Les R. Greene, Susan P. Gantt, Leah M. Niehaus, Francis Kaklauskas, Tony L. Sheppard

Counseling & Human Services Faculty Publications

This chapter captures the work of contemporary supervisors of group psychotherapy, all of whom have practiced many years and have trained and supervised innumerable group leaders. They demonstrate the diversity of settings and theoretical orientations that are prominent in the current era. Their essays speak for themselves and provide wonderful illustrations and models for supervisors-in-training and consultation to emulate. They also talk about who influenced, mentored, and supervised them.


Spirituality And Psychological Well-Being In College Students: Does Resilience Mediate This Relationship, Kevin C. Snow, Jessica Starken, Lindsay A. Phillips Jan 2026

Spirituality And Psychological Well-Being In College Students: Does Resilience Mediate This Relationship, Kevin C. Snow, Jessica Starken, Lindsay A. Phillips

Counseling & Human Services Faculty Publications

Given continued challenges of college transition and recent changes (e.g., COVID) leading to increased use of college counseling services and past studies exploring spiritualty/religion and resilience pertaining to psychological well-being (PWB), this study explored the relationship between spirituality, resilience, and PWB in college students. Three scales, the Connor-Davidson Resilience Scale, Daily Spiritual Experience Scale, and the Ryff Psychological Well-Being Scale, were used to measure the relationship between spirituality, resilience, and PWB. Results of this study showed support for the relationship between spirituality, resilience, and PWB in college students. Results also lend support for future research exploring therapeutic incorporation of spirituality …


Editorial For Issue 20(3): Special Issue: Developmental Trajectories In Lgbtqiqa+ Lifeways, Jeff Moe, Aaron Albright Jan 2026

Editorial For Issue 20(3): Special Issue: Developmental Trajectories In Lgbtqiqa+ Lifeways, Jeff Moe, Aaron Albright

Counseling & Human Services Faculty Publications

[Introduction] Hello and welcome to the community of counselors, advocates, and scholars who read the Journal of LGBTQ Issues in Counseling. Over the course of the past 20 years, affirmative counseling with and on behalf of LGBTQIQA+ people has developed into a profession-wide expectation as opposed to a specialty area. The synergy of consistent and prolonged social and professional activism with research and practice led the leaders of organizations like the American School Counselors’ Association (ASCA) and the American Counseling Association (ACA) to adopt LGBTQ+ affirmation as the ethical and professional perspective of the counseling field. The leaders of the …


Plastic Waste Imports & Coastal Litter: Evidence From Citizen Science Data, Rebecca L.C. Taylor, Hebe Williams, Shan Zhang Jan 2026

Plastic Waste Imports & Coastal Litter: Evidence From Citizen Science Data, Rebecca L.C. Taylor, Hebe Williams, Shan Zhang

Economics Faculty Publications

Plastic waste is an internationally traded commodity, where importing countries recycle plastic waste into usable materials. However, there are concerns that the importation process creates plastic litter - a negative externality - in importing countries. While this concern has received much media and policy attention, quantifying the magnitude of this externality has been hindered by a lack of data on plastic litter across countries and over time. To this end, we use unconventional citizen science data on litter from Ocean Conservancy's International Coastal Cleanup, together with the United Nations Comtrade Database, to estimate the correlation between traded plastic waste and …


Does The Use Of Protective Behavioral Strategies Moderate The Relationship Between Perceived Peer Cannabis Use And Personal Use?, Mia Forsythe, Erica E. Mcdonald, Melissa N. Manning, Audrey L. Bell, Alicia Moulder, Cathy Lau-Barraco Jan 2026

Does The Use Of Protective Behavioral Strategies Moderate The Relationship Between Perceived Peer Cannabis Use And Personal Use?, Mia Forsythe, Erica E. Mcdonald, Melissa N. Manning, Audrey L. Bell, Alicia Moulder, Cathy Lau-Barraco

Knowledge and Creativity Expo

The perception that close friends frequently use substances (i.e., descriptive norms) has been shown to increase personal use frequency and subsequent negative consequences. Within alcohol literature, protective behavioral strategies (PBS), actions aimed at reducing negative consequences of substance use (e.g., avoiding use before work), have been shown to moderate the effect of this relationship. However, this relationship in cannabis use remains unexplored. Thus, the current study examines PBS use as a moderator between descriptive norms and cannabis use frequency. We hypothesize that a positive association between descriptive norms and cannabis frequency will be weakened by greater PBS use. Undergraduate past-month …


Under Pressure: Associations Between Discrimination, Expressive Suppression, And Coping Drinking Motives Among Sexual Minority Women, Erica E. Mcdonald, Mia Forsythe, Audrey L. Bell, Melissa N. Manning, Alicia Moulder, Cathy Lau-Barraco Jan 2026

Under Pressure: Associations Between Discrimination, Expressive Suppression, And Coping Drinking Motives Among Sexual Minority Women, Erica E. Mcdonald, Mia Forsythe, Audrey L. Bell, Melissa N. Manning, Alicia Moulder, Cathy Lau-Barraco

Knowledge and Creativity Expo

Within Minority Stress Theory, heterosexist discrimination has been linked to drinking to cope (DTC) motives, or drinking as a way to manage negative emotions. DTC motives are associated with heightened negative consequences from drinking. Prior research has found that high levels of expressive suppression (i.e., inhibition of ongoing emotion-expressive behavior) confer risk for coping motivated drinking. Given sexual minority women’s (SMW) elevated risk for DTC motives, examining expressive suppression and discrimination as correlates may address an important gap in literature. Thus, the current study examined expressive suppression as a factor impacting the relationship between external discrimination and coping motives among …


A Macrocognitive Design Taxonomy For Simulation-Based Training Systems: Bridging Cognitive Theory And Human-Computer Interaction, Jessica M. Johnson Jan 2026

A Macrocognitive Design Taxonomy For Simulation-Based Training Systems: Bridging Cognitive Theory And Human-Computer Interaction, Jessica M. Johnson

Virginia Digital Maritime Center (VDMC) Faculty Publications

Simulation-based training systems are increasingly deployed to prepare learners for complex, safety-critical, and dynamic work environments. While advances in computing have enabled immersive and data-rich simulations, many systems remain optimized for procedural accuracy and surface-level task performance rather than the macrocognitive processes that underpin adaptive expertise. Macrocognition encompasses higher-order cognitive processes that are essential for performance transfer beyond controlled training conditions. When these processes are insufficiently supported, training systems risk fostering brittle strategies and negative training effects. This paper introduces a macrocognitive design taxonomy for simulation-based training systems derived from a large-scale meta-analysis examining the transfer of macrocognitive skills from …


Stages Of Being Foreign As Portrayed In Daughter Of Keltoum And Lost Birds, Fran Hassencahl Jan 2026

Stages Of Being Foreign As Portrayed In Daughter Of Keltoum And Lost Birds, Fran Hassencahl

Communication & Theatre Arts Faculty Publications

In this paper, I use the intercultural communication model, The Stages of Being Foreign, developed by anthropologist Oberg (1960) and modified by Gullahorn & Gullahorn (1963), Lewis & Jungman (1986), and Ward, Bochner, and Furnham (2001) to explain the experience of culture shock. This model describes the stages that individuals experience when they leave, either voluntarily or involuntarily, their home country/culture and must adapt to a new culture. These stages as described by Oberg are a preliminary stage (a spectator stage), an increasing participation stage, the pit of the culture shock stage, the adaptation stage, and for some migrants a …


China's Economic Retaliation Against Norway After Liu Xiaobo's 2010 Nobel Peace Prize, Ian Murphy, Shaomin Li Jan 2026

China's Economic Retaliation Against Norway After Liu Xiaobo's 2010 Nobel Peace Prize, Ian Murphy, Shaomin Li

Management Faculty Publications

This case study analyzes China's geoeconomic retaliation against Norway after the 2010 Nobel Peace Prize was awarded to Liu Xiaobo. China employed non-tariff barriers, diplomatic freezes, and restricted exchanges, severely impacting sectors like salmon exports. This occurred despite the Nobel Committee's independence from the Norwegian government. Although Norway's overall economic impact was mitigated by market adjustments, the six-year diplomatic freeze significantly influenced its human rights foreign policy. This case exemplifies China's strategic use of informal economic tools to punish and deter, showcasing the link between political sensitivities and economic leverage in international relations.


Yk-4-250, A Synthetic Telmisartan-Tempol Conjugate: Crystal Structure Of A Stabilized Free Radical Containing An Angiotensin At₁ Receptor Inhibitor, Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton Jan 2026

Yk-4-250, A Synthetic Telmisartan-Tempol Conjugate: Crystal Structure Of A Stabilized Free Radical Containing An Angiotensin At₁ Receptor Inhibitor, Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton

Department of Biomedical and Translational Sciences Faculty Publications

We report the first crystal structure of the telmisartan-tempol conjugate 2,2,6,6-tetramethyl-1-(λ'-oxidaneyl)piperidin-4-yl 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl]-[1,1'-biphenyl]-2-carboxylate free radical (YK-4-250, C₄₂H₄₆N₅O₃), a dual-function inhibitor designed to target both the angiotensin II type 1 receptor (AT₁R) and reactive oxygen species (ROS). Structural analysis reveals a unique crystal architecture in which the nitroxide radical is stabilized within a sterically protected environment while preserving the telmisartan pharmacophore essential for high-affinity receptor antagonism. YK-4-250 is a novel small-molecule conjugate of telmisartan and tempol that incorporates a catalytic stabilized nitroxide radical and was rationally designed to mitigate gastrointestinal acute radiation syndrome (GI-ARS).


The Psychiatric Burden Of Hidradenitis Suppurativa: A Trinetx Analysis Of Sex-Specific Disparities In Mental Health And Medication Use, Emily Sheetz, Julia Feord, Collette Sholi, Parker Adams, Tamas Gal, Susan G. Kornstein, Arturo Saavedra Jan 2026

The Psychiatric Burden Of Hidradenitis Suppurativa: A Trinetx Analysis Of Sex-Specific Disparities In Mental Health And Medication Use, Emily Sheetz, Julia Feord, Collette Sholi, Parker Adams, Tamas Gal, Susan G. Kornstein, Arturo Saavedra

Department of Medicine Faculty Publications

Background:

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition associated with physical and psychological burden. Prior research has shown increased rates of depression and anxiety among individuals with HS; however, sex-based disparities in the prevalence of these mental health conditions in patients with HS remain underexplored.

Objective:

To evaluate sex-based differences in the prevalence of major depressive disorder (MDD), generalized anxiety disorder (GAD), and the prescribing of antidepressants and anxiolytics among patients with HS.

Methods:

Using the TriNetX database, we identified patients over the age of 18 who had a recorded diagnosis of HS. Propensity score matching based on …


Reward Deficits In Co-Occurring Social Anxiety And Depression: The Roles Of Anhedonia, Boredom, Loneliness, And Covid-19 Social Restriction, Nathan M. Hager, Alicia L. Milam, Hannah C. Hamrick, Benjamin Swanson, Matt R. Judah Jan 2026

Reward Deficits In Co-Occurring Social Anxiety And Depression: The Roles Of Anhedonia, Boredom, Loneliness, And Covid-19 Social Restriction, Nathan M. Hager, Alicia L. Milam, Hannah C. Hamrick, Benjamin Swanson, Matt R. Judah

Psychology Faculty Publications

Prior research points toward reward deficits as crucial to the link between social anxiety disorder and major depressive disorder. However, studies have not explored specific types of reward deficits or how social-environmental factors may impact them. The current study examined whether the indirect effects of three reward deficits (anhedonia, boredom, and loneliness) accounted for the connection between social anxiety and depression. Questionnaires were collected in a sample of college students (N = 523) during the first year of the COVID-19 pandemic, allowing examination of environmental stressors (i.e., remote learning and current friend network size) on reward deficits. Indirect effect models …


Regional Oceanographic Controls On Water Column Nitrogen Fixation In Northern Australian Waters, Douglas G. Capone, Ajit Subramaniam, Yubin Raut, Joseph P. Montoya, Margaret R. Mulholland, Rachel Ann Foster, Miles Furnas, Edward J. Carpenter Jan 2026

Regional Oceanographic Controls On Water Column Nitrogen Fixation In Northern Australian Waters, Douglas G. Capone, Ajit Subramaniam, Yubin Raut, Joseph P. Montoya, Margaret R. Mulholland, Rachel Ann Foster, Miles Furnas, Edward J. Carpenter

OES Faculty Publications

Large blooms of the diazotrophic cyanobacteria, Trichodesmium, have been re-ported along the north coast of Australia and are readily evident in remote sensing images. During a research cruise in November 1999, we sampled from Townsville to Broome, examined Trichodesmium population densities and their rates of carbon and N₂ fixation alongside microscopy-based cell counts of them and other cyanobacte-rial diazotrophs. Additionally, we also enumerated the picophytoplankton community using flow-cytometry, measured bulk chlorophyll concentrations, carbon and N₂ fixation rates, and water column hydrography, enabling comparison of diazotrophic and picophytoplankton functional groups across the system. Agglomerative hierarchical clustering analysis of physicochemical oceanographic …


Uncertainty-Aware Estimation, Planning, And Control For Tracking Multiple Drifting Patches In Flow Fields, Daniel O. Akanji, Krishnanand N. Kaipa, Cong Wei Jan 2026

Uncertainty-Aware Estimation, Planning, And Control For Tracking Multiple Drifting Patches In Flow Fields, Daniel O. Akanji, Krishnanand N. Kaipa, Cong Wei

Mechanical & Aerospace Engineering Faculty Publications

In this study, we present a replay-based framework for uncertainty-aware persistent tracking of multiple advected surface patches using an autonomous marine vehicle operating in spatiotemporal-varying currents. The method combines three components: local flow estimation, covariance-aware patch-boundary propagation with intermittent boundary fusion, and mission-level scheduling over multiple patches. Each patch is represented by a polygonal boundary, whose vertices are propagated through the estimated flow field while carrying per-vertex covariance, thereby quantifying uncertainty growth during advection. A flow-aware gain-scheduled linear quadratic regulator (LQR) was designed to shape the desired surge speed to take advantage of favorable currents. When the vehicle services a …


Scanning Electron Microscopy As A Potential Tool For Distinguishing Charcoal From Dark, Oxidized, Biomass, João Vitor Dos Santos, Aleksandar I. Goranov, Lais Gomes Fregolente, Joao Marcos De Lima-Faria, Diego Stefani Teodoro Martinez, Patrick G. Hatcher Jan 2026

Scanning Electron Microscopy As A Potential Tool For Distinguishing Charcoal From Dark, Oxidized, Biomass, João Vitor Dos Santos, Aleksandar I. Goranov, Lais Gomes Fregolente, Joao Marcos De Lima-Faria, Diego Stefani Teodoro Martinez, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

Condensed aromatic carbon (ConAC) is widely used as a proxy for organic materials derived from biomass burning. However, recent evidence shows that ConAC can be also formed through nonpyrogenic oxidative processes. This study presents a proof-of-concept investigation using scanning electron microscopy (SEM) to distinguish charcoal from dark, ConAC-rich materials produced by ambient oxidation of biomass. Pine wood exposed to long-term iron-mediated oxidation was compared with unaltered wood and a controlled laboratory-generated charcoal reference. Conventional geochemical analytical methods, including benzenepoly(carboxylic acid) (BPCA) analysis, Fourier transform–ion cyclotron resonance–mass spectrometry (FT-ICR-MS), solid-state 13C nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis, confirmed substantial …


A Computational Approach To Graduated Centrifuge Profiles For Partial Gravity Planetary Environments, Cabell W. Jones Jan 2026

A Computational Approach To Graduated Centrifuge Profiles For Partial Gravity Planetary Environments, Cabell W. Jones

Mechanical & Aerospace Engineering Faculty Publications

Missions such as NASA’s Artemis and SpaceX’s Starship aspire towards creating permanent settlements beyond Earth. In order to achieve this goal, it must be considered that the gravity present on planetary surfaces such as the Moon (0.165 g) and Mars (0.378 g) may be insufficient to support human physiology for long term habitation. On near-Earth missions, issues such as muscular atrophy, neuro-ocular changes, cardiopulmonary variations, and bone mineral density loss have been observed proportional to the duration spent in microgravity. Further studies have suggested that the severity of these conditions scales linearly with decreasing gravity, meaning that astronaut health can …