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Full-Text Articles in Social and Behavioral Sciences

Access To Rehabilitation Services: A 'Fair Go' For Individuals Living With A Dementia, Victoria Traynor, Loren De Vries Jan 2016

Access To Rehabilitation Services: A 'Fair Go' For Individuals Living With A Dementia, Victoria Traynor, Loren De Vries

Faculty of Science, Medicine and Health - Papers: part A

Similar to other Western countries, approximately nine per cent of Australians aged over 65 are living with a dementia and for those aged over 85 the prevalence rate rises to up to 30 per cent. As the ageing population increases, the prevalence of dementia will increase (Guideline Adaptation Committee, 2016). It is doubtless an important healthcare issue. In the past 10 years, since the Australian Government published its first National Framework for Action on Dementia and the nomination of dementia as a National Health Priority, dementia care has achieved never imagined improvements. Dementiaspecific research and educational initiatives by the Dementia …


A New Species Of Celebochoerus (Suidae, Mammalia) From The Philippines And The Paleobiogeography Of The Genus Celebochoerus Hooijer, 1948, Thomas Ingicco, Gerrit D. Van Den Bergh, John De Vos, Abigael Castro, Noel Amano, Angel Bautista Jan 2016

A New Species Of Celebochoerus (Suidae, Mammalia) From The Philippines And The Paleobiogeography Of The Genus Celebochoerus Hooijer, 1948, Thomas Ingicco, Gerrit D. Van Den Bergh, John De Vos, Abigael Castro, Noel Amano, Angel Bautista

Faculty of Science, Medicine and Health - Papers: part A

Celebochoerus is a unique suid having extremely large upper tusks, and which was to date only known from the Pliocene-Pleistocene of Sulawesi Island in Indonesia. Here, we report on the discovery of a canine fragment referable to Celebochoerus from the Cagayan Valley of Luzon, Northern Philippines. We name a new species, Celebochoerus cagayanensis nov. sp., which differs from the Sulawesi species Celebochoerus heekereni in having mesial and distal enamel bands on the upper canines. We see these characteristics as symplesiomorphic in suids and propose a migration route from the Philippines to Sulawesi, possibly out of Taiwan, which would have occurred …


Making Sense Of Critical Participatory Action Research. Reflections On The Action Research Planner: Doing Critical Participatory Action Research, Maria T. Mackay Jan 2016

Making Sense Of Critical Participatory Action Research. Reflections On The Action Research Planner: Doing Critical Participatory Action Research, Maria T. Mackay

Faculty of Science, Medicine and Health - Papers: part A

After immersing myself in The Research Planner: Doing Critical Participatory Action Research, I believe I have a better understanding of participatory action research and its relationship to the work of Habermas. I feel it has enabled me to align my values and beliefs with Habermas and action research's philosophical underpinnings within the critical theory paradigm. For me this book has clarified how communicative spaces, the theory of communicative action and public spheres are related to participatory methodologies.


Energetics Of Communal Roosting In Chestnut-Crowned Babblers: Implications For Group Dynamics And Breeding Phenology, Mark A. Chappell, William A. Buttemer, Andrew Russell Jan 2016

Energetics Of Communal Roosting In Chestnut-Crowned Babblers: Implications For Group Dynamics And Breeding Phenology, Mark A. Chappell, William A. Buttemer, Andrew Russell

Faculty of Science, Medicine and Health - Papers: part A

For many endotherms, communal roosting saves energy in cold conditions, but how this might affect social dynamics or breeding phenology is not well understood. Using chestnut-crowned babblers (Pomatostomus ruficeps), we studied the effects of nest use and group size on roosting energy costs. These 50 g cooperatively breeding passerine birds of outback Australia breed from late winter to early summer and roost in huddles of up to 20 in single-chambered nests. We measured babbler metabolism at three ecologically relevant temperatures: 5°C (similar to minimum nighttime temperatures during early breeding), 15°C (similar to nighttime temperatures during late breeding) and 28°C (thermal …


A Rapid Burst In Hotspot Motion Through The Interaction Of Tectonics And Deep Mantle Flow, Rakib Hassan, R Dietmar Muller, Michael Gurnis, Simon E. Williams, Nicolas Flament Jan 2016

A Rapid Burst In Hotspot Motion Through The Interaction Of Tectonics And Deep Mantle Flow, Rakib Hassan, R Dietmar Muller, Michael Gurnis, Simon E. Williams, Nicolas Flament

Faculty of Science, Medicine and Health - Papers: part A

Volcanic hotspot tracks featuring linear progressions in the age of volcanism are typical surface expressions of plate tectonic movement on top of narrow plumes of hot material within Earth's mantle1. Seismic imaging reveals that these plumes can be of deep origin2-probably rooted on thermochemical structures in the lower mantle3, 4, 5, 6. Although palaeomagnetic and radiometric age data suggest that mantle flow can advect plume conduits laterally7, 8, the flow dynamics underlying the formation of the sharp bend occurring only in the Hawaiian-Emperor hotspot track in the Pacific Ocean remains enigmatic. Here we present palaeogeographically constrained numerical models of thermochemical …


An Investigation Of Future Fuel Load And Fire Weather In Australia, Hamish Clarke, Andy Pitman, Jatin Kala, Claire C. Carouge, Vanessa E. Haverd, Jason P. Evans Jan 2016

An Investigation Of Future Fuel Load And Fire Weather In Australia, Hamish Clarke, Andy Pitman, Jatin Kala, Claire C. Carouge, Vanessa E. Haverd, Jason P. Evans

Faculty of Science, Medicine and Health - Papers: part A

We present an assessment of the impact of future climate change on two key drivers of fire risk in Australia, fire weather and fuel load. Fire weather conditions are represented by the McArthur Forest Fire Danger Index (FFDI), calculated from a 12-member regional climate model ensemble. Fuel load is predicted from net primary production, simulated using a land surface model forced by the same regional climate model ensemble. Mean annual fine litter is projected to increase across all ensemble members, by 1.2 to 1.7 t ha-1 in temperate areas, 0.3 to 0.5 t ha-1 in grassland areas and 0.7 to …


Unravelling The Glass Trade Bead Sequence From Magoro Hill, South Africa: Separating Pre-Seventeenth-Century Asian Imports From Later European Counterparts, Farahnaz Koleini, Linda C. Prinsloo, Wim M. Biemond, Philippe Colomban, Anh T. Ngo, Jan C. Boeyens, Maria M. Van Der Ryst, Koos Van Brakel Jan 2016

Unravelling The Glass Trade Bead Sequence From Magoro Hill, South Africa: Separating Pre-Seventeenth-Century Asian Imports From Later European Counterparts, Farahnaz Koleini, Linda C. Prinsloo, Wim M. Biemond, Philippe Colomban, Anh T. Ngo, Jan C. Boeyens, Maria M. Van Der Ryst, Koos Van Brakel

Faculty of Science, Medicine and Health - Papers: part A

Excavations conducted between 2010 and 2012 at Magoro Hill, a site in South Africa's Limpopo Province frequented or intermittently occupied by African farming communities since the first millennium AD, yielded a substantial glass bead assemblage. A selection of the beads was studied non-destructively by classifying them according to morphological attributes, supplemented by Raman analyses and XRF measurements. It became evident that a morphological classification of beads recovered from sites that include imports into Africa after the seventeenth century AD could be problematic due to apparent morphological similarities between earlier and later beads. This paper demonstrates the use and archaeological application …


Exaggerations And Caveats In Press Releases And Health-Related Science News, Petroc Sumner, Solveiga Vivian Griffiths, Jacky Boivin, Andrew Williams, Lewis Bott, Rachel Adams, Christos Venetis, Leanne Whelan, Bethan Hughes, Christopher D. Chambers Jan 2016

Exaggerations And Caveats In Press Releases And Health-Related Science News, Petroc Sumner, Solveiga Vivian Griffiths, Jacky Boivin, Andrew Williams, Lewis Bott, Rachel Adams, Christos Venetis, Leanne Whelan, Bethan Hughes, Christopher D. Chambers

Faculty of Science, Medicine and Health - Papers: part A

Background: Exaggerated or simplistic news is often blamed for adversely influencing public health. However, recent findings suggested many exaggerations were already present in university press releases, which scientists approve. Surprisingly, these exaggerations were not associated with more news coverage. Here we test whether these two controversial results also arise in press releases from prominent science and medical journals. We then investigate the influence of mitigating caveats in press releases, to test assumptions that caveats harm news interest or are ignored.

Methods and Findings Using: quantitative content analysis, we analyzed press releases (N = 534) on biomedical and health-related science issued …


Posaconazole Therapeutic Drug Monitoring In A Regional Hospital Setting, Patrick J. Lindsay, Stuart Bond, Ross Norris, Deborah Marriott, Spiros Miyakis Jan 2016

Posaconazole Therapeutic Drug Monitoring In A Regional Hospital Setting, Patrick J. Lindsay, Stuart Bond, Ross Norris, Deborah Marriott, Spiros Miyakis

Faculty of Science, Medicine and Health - Papers: part A

BACKGROUND: Posaconazole therapeutic drug monitoring (TDM) is recommended to promote effective antifungal prophylaxis, but its utility has yet to be optimized. Breakthrough invasive fungal infections have been reported with serum concentrations/L, but there is little evidence to determine the optimal serum concentration for efficacy or concentrations associated with toxicity. Challenges for effective monitoring are greater in settings without posaconazole TDM facilities because of the long turnaround time before receipt of results.

METHODS: Thirty-eight TDM episodes were performed on 18 patients in a regional center in Australia during a 30-month period. Australian guidelines recommend a trough serum concentration of ≥700 mcg/L. …


Is Delirium Being Detected In Emergency?, Victoria Traynor, Nicholas Cordato, Pippa Burns, Yun Xu, Nicole Britten, Kim Duncan, Loren Devries, Colleen Mckinnon Jan 2016

Is Delirium Being Detected In Emergency?, Victoria Traynor, Nicholas Cordato, Pippa Burns, Yun Xu, Nicole Britten, Kim Duncan, Loren Devries, Colleen Mckinnon

Faculty of Science, Medicine and Health - Papers: part A

Objective To report on the use of Delirium Care Pathways to screen for and recognise delirium by Aged Care Services in Emergency Teams (ASETs) at five metropolitan hospitals in New South Wales, Australia. Knowledge of delirium and the use of Delirium Care Pathways are vital to ensure that older people presenting with delirium receive best practice care. Methods An audit of 205 randomly selected medical records of clients over 65 years presenting to an ASET was conducted. Results Delirium was recorded in the medical records notes of four clients (2%). However, the auditors identified another 27 clients with symptoms of …


Ability Of The 4-D-Var Analysis Of The Gosat Besd Xco2 Retrievals To Characterize Atmospheric Co2 At Large And Synoptic Scales, Sébastien Massart, Anna Agustí-Panareda, Jens Heymann, Michael Buchwitz, Frédéric Chevallier, Maximilian Reuter, Michael Hilker, J P. Burrows, Nicholas M. Deutscher, D Feist, Frank Hase, Ralf Sussmann, Filip Desmet, Manvendra K. Dubey, David W. T Griffith, Rigel Kivi, Christof Petri, Matthias Schneider, Voltaire A. Velazco Jan 2016

Ability Of The 4-D-Var Analysis Of The Gosat Besd Xco2 Retrievals To Characterize Atmospheric Co2 At Large And Synoptic Scales, Sébastien Massart, Anna Agustí-Panareda, Jens Heymann, Michael Buchwitz, Frédéric Chevallier, Maximilian Reuter, Michael Hilker, J P. Burrows, Nicholas M. Deutscher, D Feist, Frank Hase, Ralf Sussmann, Filip Desmet, Manvendra K. Dubey, David W. T Griffith, Rigel Kivi, Christof Petri, Matthias Schneider, Voltaire A. Velazco

Faculty of Science, Medicine and Health - Papers: part A

This study presents results from the European Centre for Medium-Range Weather Forecasts (ECMWF) carbon dioxide (CO2) analysis system where the atmospheric CO2 is controlled through the assimilation of column-averaged dry-air mole fractions of CO2 (XCO2) from the Greenhouse gases Observing Satellite (GOSAT). The analysis is compared to a free-run simulation (without assimilation of XCO2), and they are both evaluated against XCO2 data from the Total Carbon Column Observing Network (TCCON). We show that the assimilation of the GOSAT XCO2 product from the Bremen Optimal Estimation Differential Optical Absorption Spectroscopy (BESD) algorithm during the year 2013 provides XCO2 fields with an …


Clusterin In The Eye: An Old Dog With New Tricks At The Ocular Surface, M Elizabeth Fini, Aditi Bauskar, Shinwu Jeong, Mark R. Wilson Jan 2016

Clusterin In The Eye: An Old Dog With New Tricks At The Ocular Surface, M Elizabeth Fini, Aditi Bauskar, Shinwu Jeong, Mark R. Wilson

Faculty of Science, Medicine and Health - Papers: part A

The multifunctional protein clusterin (CLU) was first described in 1983 as a secreted glycoprotein present in ram rete testis fluid that enhanced aggregation ('clustering') of a variety of cells in vitro. It was also independently discovered in a number of other systems. By the early 1990s, CLU was known under many names and its expression had been demonstrated throughout the body, including in the eye. Its homeostatic activities in proteostasis, cytoprotection, and anti-inflammation have been well documented, however its roles in health and disease are still not well understood. CLU is prominent at fluid-tissue interfaces, and in 1996 it was …


Elucidating The Chemical Structure Of Native 1-Deoxysphingosine, Regula Steiner, Essa M. Saied, Alaa Othman, Christoph Arenz, Alan T. Maccarone, Berwyck L. J Poad, Stephen J. Blanksby, Arnold Von Eckardstein, Thorsten Hornemann Jan 2016

Elucidating The Chemical Structure Of Native 1-Deoxysphingosine, Regula Steiner, Essa M. Saied, Alaa Othman, Christoph Arenz, Alan T. Maccarone, Berwyck L. J Poad, Stephen J. Blanksby, Arnold Von Eckardstein, Thorsten Hornemann

Faculty of Science, Medicine and Health - Papers: part A

The 1-deoxysphingolipids (1-deoxySLs) are formed by an alternate substrate usage of the enzyme, serine-palmitoyltransferase, and are devoid of the C1-OH-group present in canonical sphingolipids. Pathologically elevated 1-deoxySL levels are associated with the rare inherited neuropathy, HSAN1, and diabetes type 2 and might contribute to β cell failure and the diabetic sensory neuropathy. In analogy to canonical sphingolipids, it was assumed that 1-deoxySLs also bear a (4E) double bond, which is normally introduced by sphingolipid delta(4)-desaturase 1. This, however, was never confirmed. We therefore supplemented HEK293 cells with isotope-labeled D3-1-deoxysphinganine and compared the downstream formed D3-1-deoxysphingosine (1-deoxySO) to a commercial synthetic …


How Humans Adapt To Exercising And Working In The Tropics, Nigel A.S. Taylor Jan 2016

How Humans Adapt To Exercising And Working In The Tropics, Nigel A.S. Taylor

Faculty of Science, Medicine and Health - Papers: part A

Human migration to Australia occurred over 62,000 years ago. Those first Australians established one of the oldest continuous populations on the driest of the inhabited continents, surviving the world's longest drought (>10,000 y). Indeed, the traditional owners established a cultural identity and sustainable lifestyle thousands of years before any of the more recognised ancient civilisations. However, our temperature and rainfall variations belie the national stereotype, with temperatures from -23oC (Charlotte Pass, New South Wales) to 50.7oC (Oodnadatta, South Australia), and annual rainfalls from 125 mm (Lake Eyre, South Australia) through to 12,461 mm in the tropical north-east (Bellenden Ker, …


How To Tackle The Rising Tide Of Poaching In Australia's Tropical Seas, Steven W. Purcell, Hampus B. Eriksson Jan 2016

How To Tackle The Rising Tide Of Poaching In Australia's Tropical Seas, Steven W. Purcell, Hampus B. Eriksson

Faculty of Science, Medicine and Health - Papers: part A

High-value marine species in waters off northern Australia are at increasing risk of poaching by foreign fishing crews, according to figures from the Australian Fisheries Management Authority. The number of foreign fishing boats caught in Australian waters increased from six in 2014-15 to 20 in 2015-16. These fishers have evidently come to poach species that fetch high prices and have been overfished elsewhere in the Asia-Pacific region. They seek "lootable resources" - species that are attractive to the black market because they are expensive, easy to catch and weakly regulated.


Adaptation And Acclimation Of Traits Associated With Swimming Capacity In Lake Whitefish (Coregonus Clupeaformis) Ecotypes, Martin Laporte, Anne C. Dalziel, Nicolas Martin, Louis Bernatchez Jan 2016

Adaptation And Acclimation Of Traits Associated With Swimming Capacity In Lake Whitefish (Coregonus Clupeaformis) Ecotypes, Martin Laporte, Anne C. Dalziel, Nicolas Martin, Louis Bernatchez

Faculty of Science, Medicine and Health - Papers: part A

Background: Improved performance in a given ecological niche can occur through local adaptation, phenotypic plasticity, or a combination of these mechanisms. Evaluating the relative importance of these two mechanisms is needed to better understand the cause of intra specific polymorphism. In this study, we reared populations of Lake Whitefish (Coregonus clupeaformis) representing the 'normal' (benthic form) and the 'dwarf' (derived limnetic form) ecotypes in two different conditions (control and swim-training) to test the relative importance of adaptation and acclimation in the differentiation of traits related to swimming capacity. The dwarf whitefish is a more active swimmer than the normal ecotype, …


Killing The Speckled Monster: Riots, Resistance And Reward In The Story Of Smallpox Vaccination, Kathryn M. Weston Jan 2016

Killing The Speckled Monster: Riots, Resistance And Reward In The Story Of Smallpox Vaccination, Kathryn M. Weston

Faculty of Science, Medicine and Health - Papers: part A

En route to the vaccination exhibition, it was easy to get distracted by the impressive variety of preserved specimens on display in one of London's most fascinating museums, the Hunterian. Jar upon jar of human and animal body parts as well as medical tools, skeletons, and other paraphernalia are enough to keep a visitor absorbed for hours. Happily, the Qvist gallery exhibition of Vaccination: Medicine and the Masses was equally captivating.


Sedimentological Processes And Environmental Variability At Lake Ohrid (Macedonia, Albania) Between 637 Ka And The Present, Alexander Francke, Bernd Wagner, Janna Just, Niklas Leicher, Raphael Gromig, Henrike Baumgarten, Hendrik Vogel, Jack H. Lacey, Laura Sadori, Thomas Wonik, Melanie J. Leng Jan 2016

Sedimentological Processes And Environmental Variability At Lake Ohrid (Macedonia, Albania) Between 637 Ka And The Present, Alexander Francke, Bernd Wagner, Janna Just, Niklas Leicher, Raphael Gromig, Henrike Baumgarten, Hendrik Vogel, Jack H. Lacey, Laura Sadori, Thomas Wonik, Melanie J. Leng

Faculty of Science, Medicine and Health - Papers: part A

Lake Ohrid (Macedonia, Albania) is thought to be more than 1.2 million years old and host more than 300 endemic species. As a target of the International Continental scientific Drilling Program (ICDP), a successful deep drilling campaign was carried out within the scope of the Scientific Collaboration on Past Speciation Conditions in Lake Ohrid (SCOPSCO) project in 2013. Here, we present lithological, sedimentological, and (bio-)geochemical data from the upper 247.8 m composite depth of the overall 569 m long DEEP site sediment succession from the central part of the lake. According to an age model, which is based on 11 …


Northern Mediterranean Climate Since The Middle Pleistocene: A 637 Ka Stable Isotope Record From Lake Ohrid (Albania/Macedonia), Jack H. Lacey, Melanie J. Leng, Alexander Francke, Hilary J. Sloane, Antoni Milodowski, Hendrik Vogel, Henrike Baumgarten, Giovanni Zanchetta, Bernd Wagner Jan 2016

Northern Mediterranean Climate Since The Middle Pleistocene: A 637 Ka Stable Isotope Record From Lake Ohrid (Albania/Macedonia), Jack H. Lacey, Melanie J. Leng, Alexander Francke, Hilary J. Sloane, Antoni Milodowski, Hendrik Vogel, Henrike Baumgarten, Giovanni Zanchetta, Bernd Wagner

Faculty of Science, Medicine and Health - Papers: part A

Lake Ohrid (Macedonia/Albania) is an ancient lake with unique biodiversity and a site of global significance for investigating the influence of climate, geological, and tectonic events on the generation of endemic populations. Here, we present oxygen (δ18O) and carbon (δ13C) isotope data from carbonate over the upper 243 m of a composite core profile recovered as part of the Scientific Collaboration on Past Speciation Conditions in Lake Ohrid (SCOPSCO) project. The investigated sediment succession covers the past ca. 637 ka. Previous studies on short cores from the lake (up to 15 m, < 140 ka) have indicated the total inorganic carbon (TIC) content of sediments to be highly sensitive to climate change over the last glacial-interglacial cycle. Sediments corresponding to warmer periods contain abundant endogenic calcite; however, an overall low TIC content in glacial sediments is punctuated by discrete bands of early diagenetic authigenic siderite. Isotope measurements on endogenic calcite (δ18Oc and δ13Cc) reveal variations both between and within interglacials that suggest the lake has been subject to palaeoenvironmental change on orbital and millennial timescales. We also measured isotope ratios from authigenic siderite (δ18Os and δ13Cs) and, with the oxygen isotope composition of calcite and siderite, reconstruct δ18O of lake water (δ18Olw) over the last 637 ka. Interglacials have higher δ18Olw values when compared to glacial periods most likely due to changes in evaporation, summer temperature, the proportion of winter precipitation (snowfall), and inflow from adjacent Lake Prespa. The isotope stratigraphy suggests Lake Ohrid experienced a period of general stability from marine isotope stage (MIS) 15 to MIS 13, highlighting MIS 14 as a particularly warm glacial. Climate conditions became progressively wetter during MIS 11 and MIS 9. Interglacial periods after MIS 9 are characterised by increasingly evaporated and drier conditions through MIS 7, MIS 5, and the Holocene. Our results provide new evidence for long-term climate change in the northern Mediterranean region, which will form the basis to better understand the influence of major environmental events on biological evolution within Lake Ohrid.


Ecosystem Regimes And Responses In A Coupled Ancient Lake System From Mis 5b To Present: The Diatom Record Of Lakes Ohrid And Prespa, Aleksandra Cvetkoska, Elena Jovanovska, Alexander Francke, Slavica Tofilovska, Hendrik Vogel, Zlatko Levkov, Timme H. Donders, Bernd Wagner, Friederike Wagner-Cremer Jan 2016

Ecosystem Regimes And Responses In A Coupled Ancient Lake System From Mis 5b To Present: The Diatom Record Of Lakes Ohrid And Prespa, Aleksandra Cvetkoska, Elena Jovanovska, Alexander Francke, Slavica Tofilovska, Hendrik Vogel, Zlatko Levkov, Timme H. Donders, Bernd Wagner, Friederike Wagner-Cremer

Faculty of Science, Medicine and Health - Papers: part A

We reconstruct the aquatic ecosystem interactions since the last interglacialperiod in the oldest, most diverse, hydrologically connected European lakesystem, by using palaeolimnological diatom and selected geochemistry datafrom Lake Ohrid "DEEP site" core and equivalent data from Lake Prespa core,Co1215. Driven by climate forcing, the lakes experienced two adaptive cyclesduring the last 92 ka: "interglacial and interstadial" and"glacial" cycle. The short-term ecosystems reorganizations, e.g. regimeshifts within these cycles substantially differ between the lakes, as evidentfrom the inferred amplitudes of variation. The deeper Lake Ohrid shiftedbetween ultra oligo- and oligotrophic regimes in contrast to the muchshallower Lake Prespa, which shifted from a …


Pollen-Based Paleoenvironmental And Paleoclimatic Change At Lake Ohrid (South-Eastern Europe) During The Past 500 Ka, Laura Sadori, Andreas Koutsodendris, Konstantinos Panagiotopoulos, Alessia Masi, Adele Bertini, Nathalie Combourieu-Nebout, Alexander Francke, Katerina Kouli, Sébastien Joannin, Anna M. Mercuri Jan 2016

Pollen-Based Paleoenvironmental And Paleoclimatic Change At Lake Ohrid (South-Eastern Europe) During The Past 500 Ka, Laura Sadori, Andreas Koutsodendris, Konstantinos Panagiotopoulos, Alessia Masi, Adele Bertini, Nathalie Combourieu-Nebout, Alexander Francke, Katerina Kouli, Sébastien Joannin, Anna M. Mercuri

Faculty of Science, Medicine and Health - Papers: part A

Lake Ohrid is located at the border between FYROM (Former Yugoslavian Republic of Macedonia) and Albania and formed during the latest phases of Alpine orogenesis. It is the deepest, the largest and the oldest tectonic lake in Europe. To better understand the paleoclimatic and paleoenvironmental evolution of Lake Ohrid, deep drilling was carried out in 2013 within the framework of the Scientific Collaboration on Past Speciation Conditions (SCOPSCO) project that was funded by the International Continental Scientific Drilling Program (ICDP). Preliminary results indicate that lacustrine sedimentation of Lake Ohrid started between 1.2 and 1.9 Ma ago. Here we present new …


Differential Resilience Of Ancient Sister Lakes Ohrid And Prespa To Environmental Disturbances During The Late Pleistocene, Elena Jovanovska, Aleksandra Cvetkoska, Torsten Hauffe, Zlatko Levkov, Bernd Wagner, Roberto Sulpizio, Alexander Francke, Christian Albrecht, Thomas Wilke Jan 2016

Differential Resilience Of Ancient Sister Lakes Ohrid And Prespa To Environmental Disturbances During The Late Pleistocene, Elena Jovanovska, Aleksandra Cvetkoska, Torsten Hauffe, Zlatko Levkov, Bernd Wagner, Roberto Sulpizio, Alexander Francke, Christian Albrecht, Thomas Wilke

Faculty of Science, Medicine and Health - Papers: part A

Ancient lakes, such as lakes Ohrid and Prespa on the Balkan Peninsula, have become model systems for studying the link between geological and biotic evolution. Recently, the scientific deep-drilling project Scientific Collaboration on Past Speciation Conditions in Lake Ohrid (SCOPSCO) was initiated to better understand the environmental, climatic, and limnological evolution of the lake. It revealed that Lake Ohrid experienced a number of environmental disturbances during its ca. 2.0 million year long history. These are comprised of disturbances that lasted over longer periods of time ("press events") such as glacial-interglacial cycles and Heinrich events, as well as sudden and short …


Aligning And Synchronization Of Mis5 Proxy Records From Lake Ohrid (Fyrom) With Independently Dated Mediterranean Archives: Implications For Deep Core Chronology, Giovanni Zanchetta, Eleonora Regattieri, Biagio Giaccio, Bernd Wagner, Roberto Sulpizio, Alexander Francke, Hendrik Vogel, Laura Sadori, Alessia Masi, Gaia Sinopoli Jan 2016

Aligning And Synchronization Of Mis5 Proxy Records From Lake Ohrid (Fyrom) With Independently Dated Mediterranean Archives: Implications For Deep Core Chronology, Giovanni Zanchetta, Eleonora Regattieri, Biagio Giaccio, Bernd Wagner, Roberto Sulpizio, Alexander Francke, Hendrik Vogel, Laura Sadori, Alessia Masi, Gaia Sinopoli

Faculty of Science, Medicine and Health - Papers: part A

The DEEP site sediment sequence obtained during the ICDP SCOPSCO project at Lake Ohrid was dated using tephrostratigraphic information, cyclostratigraphy, and orbital tuning through the marine isotope stages (MIS) 15-1. Although this approach is suitable for the generation of a general chronological framework of the long succession, it is insufficient to resolve more detailed palaeoclimatological questions, such as leads and lags of climate events between marine and terrestrial records or between different regions. Here, we demonstrate how the use of different tie points can affect cyclostratigraphy and orbital tuning for the period between ca. 140 and 70 ka and how …


Complexity Of Diatom Response To Lateglacial And Holocene Climate And Environmental Change In Ancient, Deep And Oligotrophic Lake Ohrid (Macedonia And Albania), Xiaosen Zhang, Jane M. Reed, Jack H. Lacey, Alexander Francke, Melanie J. Leng, Zlatko Levkov, Bernd Wagner Jan 2016

Complexity Of Diatom Response To Lateglacial And Holocene Climate And Environmental Change In Ancient, Deep And Oligotrophic Lake Ohrid (Macedonia And Albania), Xiaosen Zhang, Jane M. Reed, Jack H. Lacey, Alexander Francke, Melanie J. Leng, Zlatko Levkov, Bernd Wagner

Faculty of Science, Medicine and Health - Papers: part A

Lake Ohrid (Macedonia and Albania) is a rare example of a deep, ancient Mediterranean lake and is a key site for palaeoclimate research in the northeastern Mediterranean region. This study conducts the analysis of diatoms as a proxy for Lateglacial and Holocene climate and environmental change in Lake Ohrid at a higher resolution than in previous studies. While Lake Ohrid has the potential to be sensitive to water temperature change, the data demonstrate a highly complex diatom response, probably comprising a direct response to temperature-induced lake productivity in some phases and an indirect response to temperature-related lake stratification or mixing …


Speeding Up Biomolecular Interactions By Molecular Sledding, Alexander Turkin, Lei Zhang, Alessio Marcozzi, Walter F. Mangel, Andreas Herrmann, Antoine M. Van Oijen Jan 2016

Speeding Up Biomolecular Interactions By Molecular Sledding, Alexander Turkin, Lei Zhang, Alessio Marcozzi, Walter F. Mangel, Andreas Herrmann, Antoine M. Van Oijen

Faculty of Science, Medicine and Health - Papers: part A

Numerous biological processes involve association of a protein with its binding partner, an event that is preceded by a diffusion-mediated search bringing the two partners together. Often hindered by crowding in biologically relevant environments, three-dimensional diffusion can be slow and result in long bimolecular association times. Similarly, the initial association step between two binding partners often represents a rate-limiting step in biotechnologically relevant reactions. We demonstrate the practical use of an 11-a.a. DNA-interacting peptide derived from adenovirus to reduce the dimensionality of diffusional search processes and speed up associations between biological macromolecules. We functionalize binding partners with the peptide and …


The Healthy Primary School Of The Future: Study Protocol Of A Quasi-Experimental Study, M Willeboordse, M Jansen, S Van Den Heijkant, A Simons, B Winkens, Renate H. M De Groot, N Bartelink, S Kremers, P Van Assema, H Savelberg, E De Neubourg, L Borghans, T Schils, K Coppens, R Dietvorst, R Ten Hoopen, F Coomans, S Klosse, M Conjaerts, M Oosterhoff, M Joore, Isabel Ferreira, P Muris, H Bosma, H Toppenberg, C Van Schayck Jan 2016

The Healthy Primary School Of The Future: Study Protocol Of A Quasi-Experimental Study, M Willeboordse, M Jansen, S Van Den Heijkant, A Simons, B Winkens, Renate H. M De Groot, N Bartelink, S Kremers, P Van Assema, H Savelberg, E De Neubourg, L Borghans, T Schils, K Coppens, R Dietvorst, R Ten Hoopen, F Coomans, S Klosse, M Conjaerts, M Oosterhoff, M Joore, Isabel Ferreira, P Muris, H Bosma, H Toppenberg, C Van Schayck

Faculty of Science, Medicine and Health - Papers: part A

Background: Unhealthy lifestyles in early childhood are a major global health challenge. These lifestyles often persist from generation to generation and contribute to a vicious cycle of health-related and social problems. This design article presents a study evaluating the effects of two novel healthy school interventions. The main outcome measure will be changes in children's body mass index (BMI). In addition, lifestyle behaviours, academic achievement, child well-being, socio-economic differences, and societal costs will be examined. Methods: In close collaboration with various stakeholders, a quasi-experimental study was developed, for which children of four intervention schools (n = 1200) in the southern …


What Can The Life Course Approach Contribute To An Understanding Of Longevity Risk?, David Blane, Bola Akinwale, Rebecca Landy, Katey Matthews, Morten Wahrendorf, Hans-­‐Werner Wahl, Mark Hayward, Aart Liefbroer, Gita Mishra, Isabel Ferreira, Ilona Koupil Jan 2016

What Can The Life Course Approach Contribute To An Understanding Of Longevity Risk?, David Blane, Bola Akinwale, Rebecca Landy, Katey Matthews, Morten Wahrendorf, Hans-­‐Werner Wahl, Mark Hayward, Aart Liefbroer, Gita Mishra, Isabel Ferreira, Ilona Koupil

Faculty of Science, Medicine and Health - Papers: part A

Longevity risk means living longer than predicted. Attempts to understand longevity risk to date have concentrated on single diseases, usually coronary heart disease, and sought explanations in terms of risk factor change and medical innovation. In an opening paper, David Blane and colleagues point to evidence that suggests changes in positive health also should be considered; and that a life course approach can do so in a way that is socially and biologically plausible. Applying this approach to UK citizens currently aged 85 years suggests that life course research should give priority to trajectories across the whole life course and …


Food Security, Food Systems And Food Sovereignty In The 21st Century: A New Paradigm Required To Meet Sustainable Development Goals, Karen E. Charlton Jan 2016

Food Security, Food Systems And Food Sovereignty In The 21st Century: A New Paradigm Required To Meet Sustainable Development Goals, Karen E. Charlton

Faculty of Science, Medicine and Health - Papers: part A

This first issue of the Nutrition & Dietetics for 2016 focuses on food security. As an introduction to the broad spectrum of papers contained therein, this review will consider current definitions of food insecurity and then go on to discuss how to address the determinants of food insecurity (Table 1)4 within a new paradigm defined by the SDGs, as follows: • People (end poverty and hunger); • Planet (ensure sustainability of resources and arrest climate change); • Prosperity (encourage equity and promote technological advancement); and • Peace Partnership (strengthen global solidarity). The review will also consider training and educational needs …


Understanding The Importance Of Collecting Qualitative Data Creatively, Elizabeth J. Halcomb Jan 2016

Understanding The Importance Of Collecting Qualitative Data Creatively, Elizabeth J. Halcomb

Faculty of Science, Medicine and Health - Papers: part A

IN ITS broadest sense, qualitative research encompasses any study that does not use statistical methods or quantify results (Strauss and Corbin 1990). Qualitative researchers undertake their work in the natural setting, attempting to understand or interpret phenomena in terms of the meanings people bring to them.


Indicator-Based Assessment Of Climate-Change Impacts On Coasts: A Review Of Concepts, Methodological Approaches And Vulnerability Indices, Thang T. X Nguyen, Jarbas Bonetti, Kerrylee Rogers, Colin D. Woodroffe Jan 2016

Indicator-Based Assessment Of Climate-Change Impacts On Coasts: A Review Of Concepts, Methodological Approaches And Vulnerability Indices, Thang T. X Nguyen, Jarbas Bonetti, Kerrylee Rogers, Colin D. Woodroffe

Faculty of Science, Medicine and Health - Papers: part A

Increasing human pressures on coastlines and associated threats posed by sea-level rise have stimulated development of a range of different concepts and methodological approaches to assess coastal vulnerability. The first section of this paper summarizes the concepts associated with vulnerability, natural hazards and climate change. The most widely adopted analytical approaches to vulnerability assessment are described, including spatial scales, the need for hybrid approaches comprising both biophysical and social dimensions of vulnerability, and the gradual incorporation of resilience aspects into such methodologies. In particular, the development and application of vulnerability indices is examined, based on a review of more than …