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Marginal Regression Of Gaps Between Recurrent Events, Yijian Huang, Ying Qing Chen
Marginal Regression Of Gaps Between Recurrent Events, Yijian Huang, Ying Qing Chen
U.C. Berkeley Division of Biostatistics Working Paper Series
Recurrent event data typically exhibit the phenomenon of intra-individual correlation, owing to not only observed covariates but also random effects. In many applications, the population can be reasonably postulated as a heterogeneous mixture of individual renewal processes, and the inference of interest is the effect of individual-level covariates. In this article, we suggest and investigate a marginal proportional hazards model for gaps between recurrent events. A connection is established between observed gap times and clustered survival data, however, with informative cluster size. We then derive a novel and general inference procedure for the latter, based on a functional formulation of …