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Johns Hopkins University, Dept. of Biostatistics Working Papers

Numerical Analysis and Computation

Mixed models

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Spatially Adaptive Bayesian P-Splines With Heteroscedastic Errors, Ciprian M. Crainiceanu, David Ruppert, Raymond J. Carroll Nov 2004

Spatially Adaptive Bayesian P-Splines With Heteroscedastic Errors, Ciprian M. Crainiceanu, David Ruppert, Raymond J. Carroll

Johns Hopkins University, Dept. of Biostatistics Working Papers

An increasingly popular tool for nonparametric smoothing are penalized splines (P-splines) which use low-rank spline bases to make computations tractable while maintaining accuracy as good as smoothing splines. This paper extends penalized spline methodology by both modeling the variance function nonparametrically and using a spatially adaptive smoothing parameter. These extensions have been studied before, but never together and never in the multivariate case. This combination is needed for satisfactory inference and can be implemented effectively by Bayesian \mbox{MCMC}. The variance process controlling the spatially-adaptive shrinkage of the mean and the variance of the heteroscedastic error process are modeled as log-penalized …