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Full-Text Articles in Statistical Models
Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook
Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook
Undergraduate Research and Scholarship Symposium
Single-nucleotide polymorphisms (SNPs) are variations in the genome where one base pair can differ between individuals.1 SNPs occur throughout the genome and can correlate to a disease-state if they occur in a functional region of DNA.1According to the central dogma of molecular biology, any variation in the DNA sequence will have a direct effect on the RNA sequence and will potentially alter the identity or conformation of a protein product. A single RNA molecule, due to intramolecular base pairing, can acquire a plethora of 3-D conformations that are described by its structural ensemble. One SNP, rs12477830, which …