Open Access. Powered by Scholars. Published by Universities.®

Statistical Models Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Statistical Models

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen Jan 2024

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …


Bayesian Analysis For The Intraclass Model And For The Quantile Semiparametric Mixed-Effects Double Regression Models, Duo Zhang Jan 2019

Bayesian Analysis For The Intraclass Model And For The Quantile Semiparametric Mixed-Effects Double Regression Models, Duo Zhang

Dissertations, Master's Theses and Master's Reports

This dissertation consists of three distinct but related research projects. The first two projects focus on objective Bayesian hypothesis testing and estimation for the intraclass correlation coefficient in linear models. The third project deals with Bayesian quantile inference for the semiparametric mixed-effects double regression models. In the first project, we derive the Bayes factors based on the divergence-based priors for testing the intraclass correlation coefficient (ICC). The hypothesis testing of the ICC is used to test the uncorrelatedness in multilevel modeling, and it has not well been studied from an objective Bayesian perspective. Simulation results show that the two sorts …


Inference From Network Data In Hard-To-Reach Populations, Isabelle Beaudry Mar 2017

Inference From Network Data In Hard-To-Reach Populations, Isabelle Beaudry

Doctoral Dissertations

The objective of this thesis is to develop methods to make inference about the prevalence of an outcome of interest in hard-to-reach populations. The proposed methods address issues specific to the survey strategies employed to access those populations. One of the common sampling methodology used in this context is respondent-driven sampling (RDS). Under RDS, the network connecting members of the target population is used to uncover the hidden members. Specialized techniques are then used to make inference from the data collected in this fashion. Our first objective is to correct traditional RDS prevalence estimators and their associated uncertainty estimators for …