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Full-Text Articles in Statistical Models
Interval Estimation Of Proportion Of Second-Level Variance In Multi-Level Modeling, Steven Svoboda
Interval Estimation Of Proportion Of Second-Level Variance In Multi-Level Modeling, Steven Svoboda
The Nebraska Educator: A Student-Led Journal
Physical, behavioral and psychological research questions often relate to hierarchical data systems. Examples of hierarchical data systems include repeated measures of students nested within classrooms, nested within schools and employees nested within supervisors, nested within organizations. Applied researchers studying hierarchical data structures should have an estimate of the intraclass correlation coefficient (ICC) for every nested level in their analyses because ignoring even relatively small amounts of interdependence is known to inflate Type I error rate in single-level models. Traditionally, researchers rely upon the ICC as a point estimate of the amount of interdependency in their data. Recent methods utilizing an …
Statistical Methodology To Establish A Benchmark For Evaluating Antimicrobial Resistance Genes Through Real Time Pcr Assay, Enakshy Dutta
Statistical Methodology To Establish A Benchmark For Evaluating Antimicrobial Resistance Genes Through Real Time Pcr Assay, Enakshy Dutta
Department of Statistics: Dissertations, Theses, and Student Work
Novel diagnostic tests are usually compared with gold standard tests for evaluating diagnostic accuracy. For assessing antimicrobial resistance (AMR) to bovine respiratory disease (BRD) pathogens, phenotypic broth microdilution method is used as gold standard (GS). The objective of the thesis is to evaluate the optimal cycle threshold (Ct) generated by real-time polymerase chain reaction (rtPCR) to genes that confer resistance that will translate to the phenotypic classification of AMR. Data from two different methodologies are assessed to identify Ct that will discriminate between resistance (R) and susceptibility (S). First, the receiver operating characteristic (ROC) curve was used to determine the …