Design of Experiments and Sample Surveys Commons^™

Evaluation Of Program Outcomes: Assessment In Children, Cheryl M. Romano

Loma Linda University Electronic Theses, Dissertations & Projects

In an age of increased concern for accountability and the review of services, administrators of health programs should be able to present their clinics effectiveness, and demonstrate their excellent service to the community, along with providing evidence for the continued need of such clinics. Outcome evaluation plays an integral part in providing this information, and is intended to provide information concerning the effectiveness of a particular program, thus allowing for modification, and even better outcomes.

This project addressed pre and post functioning in children referred for academic and/or behavioral difficulties, in a university of health sciences-based clinic. The aim was …

Comparing The Use Of A Manual And A Power Toothbrush By 3-To-4 Year-Old Children, Lorena Delgado Salcedo

Loma Linda University Electronic Theses, Dissertations & Projects

PURPOSE: To compare the ability of three-to four-year-old children in performing toothbrushing with manual versus battery-powered toothbrushes with and without oral hygiene instructions.

METHODS: This study was a randomized, controlled, examiner-blind, 4-period crossover design performed on 50 healthy children, ages 3 to 4 years old. Children were assigned either a manual or power toothbrush at visit one and alternated between the two types of toothbrushes each week, for four weeks. Plaque was scored before and after brushing using the Greene and Vermillion -Simplified Oral Hygiene Index. ^18,19 At their last two visits of the study, the children received brushing instructions …

The Effect Of Calcium Hydroxide Pastes On Root Dentin Fracture Resistance, Kurt W. Sturz

Loma Linda University Electronic Theses, Dissertations & Projects

Calcium hydroxide is a common intracanal medicament used in the treatment of immature teeth that have been subjected to trauma or decay prior to root canal therapy. The effect of calcium hydroxide on immature root dentin is important. One area of concern is the effect that calcium hydroxide has on the fracture resistance of an immature tooth. It is the aim of this study to compare the effect of four different commercially available calcium hydroxide pastes on the fracture resistance of bovine teeth. Seventy-five freshly extracted, intact bovine incisors were prepared according to a modified Haapasalo and Orstavik technique. Each …

Principal Stratification Designs To Estimate Input Data Missing Due To Death, Constantine E. Frangakis, Donald B. Rubin, Ming-Wen An, Ellen Mackenzie

Johns Hopkins University, Dept. of Biostatistics Working Papers

We consider studies of cohorts of individuals after a critical event, such as an injury, with the following characteristics. First, the studies are designed to measure “input” variables, which describe the period before the critical event, and to characterize the distribution of the input variables in the cohort. Second, the studies are designed to measure “output” variables, primarily mortality after the critical event, and to characterize the predictive (conditional) distribution of mortality given the input variables in the cohort. Such studies often possess the complication that the input data are missing for those who die shortly after the critical event …

Multiple Imputation In The Presence Of Outliers, Michael Elliott

The University of Michigan Department of Biostatistics Working Paper Series

We consider the problem of obtaining population-based inference in the presence of missing data and outliers in the context of estimating obesity prevalence and body-mass index (BMI) measures from the Healthy For Life Study. Identifying multiple outliers in a multivariate setting is problematic because of problems such as masking, in which groups of outliers inflate the covariance matrix in a fashion that prevents their identification when included, and swamping, in which outliers skew covariances in a fashion that make non-outling observations appear to be outliers. We develop a latent class model that assumes each observation belongs to one of $K$ …

A General Framework For Statistical Performance Comparison Of Evolutionary Computation Algorithms, David Shilane, Jarno Martikainen, Sandrine Dudoit, Seppo Ovaska

U.C. Berkeley Division of Biostatistics Working Paper Series

This paper proposes a statistical methodology for comparing the performance of evolutionary computation algorithms. A two-fold sampling scheme for collecting performance data is introduced, and these data are analyzed using bootstrap-based multiple hypothesis testing procedures. The proposed method is sufficiently flexible to allow the researcher to choose how performance is measured, does not rely upon distributional assumptions, and can be extended to analyze many other randomized numeric optimization routines. As a result, this approach offers a convenient, flexible, and reliable technique for comparing algorithms in a wide variety of applications.

2^K Factorials In Blocks Of Size 2, With Application To Two-Color Microarray Experiments, Kathleen F. Kerr

UW Biostatistics Working Paper Series

When a two-level design must be run in blocks of size two, there is a unique blocking scheme that enables estimation of all the main effects. Unfortunately this design does not enable estimation of any two-factor interactions. When the experimental goal is to estimate all main effects and two-factor interactions, it is necessary to combine replicates of the experiment that use different blocking schemes. In this paper we identify such designs for up to eight factors that enable estimation of all main effects and two-factor interactions with the fewest number of replications. In addition, we give a construction for general …