Design of Experiments and Sample Surveys Commons^™

Regulation Of Biomedical Research, Andrew N. Rowan

Experimentation Collection

The idea of abolishing or simplifying government regulations has a large following in Washington at the moment. As Reagan and his minions start to prune the growth of the past twenty years, we must hope that they are able to distinguish between the healthy growth which provides needed support and the unnecessary growth which strangles necessary initiatives. However, there is one area where we need more regulation rather than less, namely, biomedical research. In calling for more regulation in biomedical research, I do not mean the imposition of outside controls by allegedly ignorant and insensitive bureaucrats (although I think some …

History Of Animal Experimentation Control In The U.K., Judith E. Hampson

Laws and Legislation Collection

The legislative control of the use of animals in experiments in the UK lies in the Cruelty to Animals Act of 1876. Animal Welfare groups and individuals in Britain have pressed for reform of this law almost since its inception 105 years ago, and the British government has recently agreed to bring this legislation up to date. Any new or amended legislation could have far-reaching implications, both for laboratory animal welfare and upon the scientific community and is therefore of considerable importance both in this country and overseas. No proper appreciation of the problem would be possible without reference to …

The Effect Of Periapical Inflammation On Cellular Cementum : A Scanning Electron Microscope Study, Gary S. Yonemoto

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to obtain information on the morphologic changes that occur in cellular cementum exposed to periapical inflammation.

Ten single rooted human teeth were collected. There were five specimens of normal cellular cementum and five specimens of diseased cellular cementum, which had been exposed to periapical inflammation. Each specimen was fractured longitudinally through the apical foramen, leaving the organic component intact. The cross-sectional morphology of cellular cementum was then examined using an ARM Model 1000 scanning electron microscope. Energy dispersive x-ray spectrometry was also conducted on samples representative of the two test groups.

A methodology was …

Influence Of Denervation And Hemithyroidectomy On The Age Related Increase In The Number Of Calcitonin-Containing Cells In Mouse Thyroid, Nualnoi Wechbanjong

Loma Linda University Electronic Theses, Dissertations & Projects

It has been concluded from this study that nerve fibers in the superior laryngeal nerves have an influence on the development of C-cells in the mouse thyroid. This conclusion is based on the results of two types of investigation. The first is an analysis of the effect of age on the number of C-cells and the second is an investigation of the influence of denervation and hemithyroid-parathyroidectomy on the age related changes in C-cells numbers.

I. The distribution and c011centraticn of C-cells in mouse thyroid at various ages.

Serial 6 µm sections of thyroid glands from Swjss Webster mice at …

Fisheries Report No 25 - The Western Australian Amateur Fishery For Australian Herring (Arripis Georgianus) - Results Of The 1973 Creel Census, R C.J. Lenanton, N. G. Hall

Fisheries Research Reports

Historically, the Western Australian production of Australian herring (Arrtpts georgtanus) has fluctuated from year to year in response to changing market demand. Prior to 1968, the annual catch taken by professional fishermen was relatively stable, ranging from 200 000 kg (approx. 500 000 pounds) to 450 000 kg (approx. 1 000 000 pounds). From 1968, commercial production has risen to a peak of 1 187 440 kg (2 617 857 pounds) recorded in 1972/73 (Table I). An increase in demand for herring as bait for the rock lobster fishery is considered to be the major factor involved in this observed …

Performance Appraisal In Hospital Dietary Departments, Mary C. Law

Loma Linda University Electronic Theses, Dissertations & Projects

The specific objectives of this research were to (1) identify the principal characteristics and functions of performance appraisal programs utilized in hospital dietary departments, (2) determine the ten major factors in performance appraisal as indicated by the hospital dietary department directors as well as by dietetic interns and the factors indicated in the review of literature, and (3) develop an evaluation form for performance appraisal of hospital dietary department employees utilizing criteria obtained from (1) and (2).

Three hundred general, short term, nonprofit hospitals were included into the study. Questionnaires were mailed to three hospitals which were classified according to …

The Psychological Needs Of Hospital Dietary Supportive Personnel, Ralph Morales Jr.

Loma Linda University Electronic Theses, Dissertations & Projects

Achieving objectives in hospital food service systems is made more critical by the increasing rate of labor turnover. One of the major emphases that seems to offer promise for solving certain current manpower problems is a better understanding of the factors which may contribute to turnover. A quantitative approach to the identification of human needs in the work environment should provide information relevant to more effective planning and utilization of human resources.

The purpose of this research was to determine if by examining the psychological needs of hospital dietary supportive personnel, information could be derived for more objective management of …

An In Vivo Perfusion Apparatus For Studies On Gingival Disease In The Albino Rat : Assessment By A Perfusion Of The Enzymes Collagenase And Hyaluronidase, James A. Smith

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis describes an in vivo perfusion apparatus which can continuously deliver controlled quantities of solutions to localized, contralateral intraoral areas in albino rats. Three animals were per fused on the experimental area (the mesial sulcular area of the maxillary first molar) on one side with tap water and Trypan blue. Localization of the solution delivered and minimal histological changes due to the presence of the apparatus was demonstrated on these animals. Solutions of .5%, 1%, and 2% hyaluronidase and collagenase were perfused on the experimental areas of nine animals. When both enzymes were used, hyaluronidase always preceded collagenase in …

The Effect Of Removing The Crevicular Epithelium Upon Canine Tooth Replantation, Leon A. Leonard

Loma Linda University Electronic Theses, Dissertations & Projects

The nature of epithelium and the remarkable facility with which it aggressively covers granulation tissue, suggests that removal of the sulcular epithelium surrounding the extraction wound of a tooth to be replanted could promote reattachment of the periodontal tissues at a more nearly ideal coronal level. To investigate this hypothesis twenty mature teeth in five mongrel dogs were experimentally replanted. One half of them were replanted in alveoli around which the crevicular epithelium had been removed, the remaining teeth without creviculoectomy acting as controls. Animals were euthanized at one, two, three, five, and sixteen weeks. After clinical evaluation of the …

Craniofacial Changes Resulting From Expansion Of The Midpalatal Suture In The Macaca Mulatta Monkey As Revealed By Roentgenographic Analysis, Raymond M. Sugiyama

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine the effects of midpalatal suture separation on the craniofacial complex by quantitative roentgenographic analysis.

Ten female Macaca mulatta monkeys were randomly grouped for experimentation. Six animals were paired in groups for two months of treatment, four months of treatment followed by two months of post retention, and six months of treatment. The four remaining monkeys were paired and served as control animals for two and six month periods. Total activation of the expansion appliances in the treated animals was completed over a three week period.

The findings of this study were based …

A Survey Of The Breakfast And Snack Habits Of Adventist And Non-Adventist Adolescents, Consuelo A. Bustista

Loma Linda University Electronic Theses, Dissertations & Projects

A study was undertaken to survey by questionnaire and interview methods the breakfast and snack habits of Adventist and non-Adventist adolescents. The purposes of the study were: (I) to find out if there is any difference in the practices of Adventist and non-Adventist teenagers, and (2) to determine their attitudes toward snacking and omission of breakfast.

Results of the questionnaire were coded, punched onto IBM cards, and fed into computing machines for item and statistical analysis. Chi-square test analyses were done on denominational classification against some questions of interest to show any significant differences between Adventist and non-Adventist students' responses. …

A Comparative Study Of The 5- And 3-Meal Plans In Six Convalescent Hospitals In San Bernardino County, Donna J. Meek

Loma Linda University Electronic Theses, Dissertations & Projects

A study comparing the 3- and 5-meal plans of food service, as used in long-stay geriatric units in San Bernardino County, have been compared. Three homes utilizing the 5-meal plan and three utilizing the 3-meal plan, to serve as controls, were chosen. A random sample of ten patients from each home was observed for three days to find the daily average nutrients in the foods served, eaten, and wasted. Also, interviews to compare factual information and attitudes were utilized for sample patients and personnel. The nutritional data was analyzed on the computer.

The results indicated that those on the 5-meal …

Application Of Knowledge Of Medications By Senior Students In A Selected School Of Nursing, Patricia H. Okimi

Loma Linda University Electronic Theses, Dissertations & Projects

The problem arose from the need to study the present method of pharmacology instruction in a selected school of nursing. "How much knowledge of medications do selected senior students have, and how do they apply their knowledge in the administration of medications?"

For this study, the normative survey approach was used as the method of research. Eleven senior students of nursing engaged in the administration of medications, as team leaders, were observed and questioned on two different occasions during one quarter of their school year. The tool of research used to collect data was an observation code sheet developed for …

Studies Concerning The Elimination Of Experimental Error In Comparative Crop Tests, T. A. Kiesselbach

Nebraska Agricultural Experiment Station: Historical Research Bulletins

It is apparent that many sources of error have unconsciously entered into comparative crop yield tests. The very important matter of overcoming variation in soil conditions as a source of experimental error has been quite extensively studied and reported by various investigators during the past decade. The means suggested for reducing such error have been (1) repetition of plats and (2) correction of yields according to check plats planted to a uniform variety or treatment at stated intervals. Both methods have proved of value and a combination of both may often be used advantageously. Some danger always exists of error …