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Full-Text Articles in Biostatistics
Compound Treatments, Transportability, And The Structural Causal Model: The Power And Simplicity Of Causal Graphs., Maya Petersen
Compound Treatments, Transportability, And The Structural Causal Model: The Power And Simplicity Of Causal Graphs., Maya Petersen
Maya Petersen
No abstract provided.
On The Statistical Accuracy Of Biomarker Assays Of Hiv Incidence, Ron Brookmeyer
On The Statistical Accuracy Of Biomarker Assays Of Hiv Incidence, Ron Brookmeyer
Ron Brookmeyer
Objective: To evaluate the statistical accuracy of estimates of current HIV incidence rates from cross-sectional surveys, and to identify characteristics of assays that improve accuracy.
Methods: Performed mathematical and statistical analysis of the cross-sectional estimator of HIV incidence to evaluate bias and variance. Developed probability models to evaluate impact of long tails of the window period distribution on accuracy.
Results: The standard cross-sectional estimate of HIV incidence rate is estimating a time-lagged incidence where the lag time, called the shadow, depends on the mean and the coefficient of variation of window periods. Equations show how the shadow increases with the …