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Full-Text Articles in Biostatistics
Genome-Wide Analysis Of Alternative Rna Splicing In Children With Acute Myeloid Leukemia (Aml), Xichen Li
Genome-Wide Analysis Of Alternative Rna Splicing In Children With Acute Myeloid Leukemia (Aml), Xichen Li
Shared Knowledge Conference
The pediatric Acute Myeloid Leukemia (AML) is a high-risk and hard-to-treat childhood cancer that originates in the bone marrow from immature white blood cells. Recently, more and more evidence indicates that aberrant splicing of genes is a common characteristic for AML. Gene expression profiles have proved extremely useful for identifying genes that are associated with clinical characteristics and survival outcome of cancer patients. However, conventional gene expression profiles do not account for the differences observed in expressed isoforms when alternative RNA splicing is analyzed. Alternative RNA splicing can generate dozens of distinct transcripts from individual genes and the expressions of …
Analysis Of Ranked Gene Tree Probability Distributions Under The Coalescent Process For Detecting Anomaly Zones, Anastasiia Kim
Analysis Of Ranked Gene Tree Probability Distributions Under The Coalescent Process For Detecting Anomaly Zones, Anastasiia Kim
Shared Knowledge Conference
In phylogenetic studies, gene trees are used to reconstruct species tree. Under the multispecies coalescent model, gene trees topologies may differ from that of species trees. The incorrect gene tree topology (one that does not match the species tree) that is more probable than the correct one is termed anomalous gene tree (AGT). Species trees that can generate such AGTs are said to be in the anomaly zone (AZ). In this region, the method of choosing the most common gene tree as the estimate of the species tree will be inconsistent and will converge to an incorrect species tree when …
Quantitative Electroencephalography For Detecting Concussions, Sara Krehbiel, Kathy Hoke, Joanna Wares
Quantitative Electroencephalography For Detecting Concussions, Sara Krehbiel, Kathy Hoke, Joanna Wares
Biology and Medicine Through Mathematics Conference
No abstract provided.