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Full-Text Articles in Biostatistics

Addition To Pglr Chap 6, Joseph M. Hilbe Aug 2016

Addition To Pglr Chap 6, Joseph M. Hilbe

Joseph M Hilbe

Addition to Chapter 6 in Practical Guide to Logistic Regression. Added section on Bayesian logistic regression using Stata.


Testing Homogeneity In Semiparametric Mixture Case-Control Models, C Z. Di, G Kc Chan, C Zheng, Ky Liang Jun 2016

Testing Homogeneity In Semiparametric Mixture Case-Control Models, C Z. Di, G Kc Chan, C Zheng, Ky Liang

Chongzhi Di

Recently, Qin and Liang (Biometrics, 2011) considered a semiparametric mixture case-control model and proposed a score test for homogeneity. The mixture model is semiparametric in the sense that the density ratio of two distributions is assumed to be of exponential form, while the baseline density is unspecified. In a family of parametric admixture models, Di and Liang (Biometrics, 2011) showed that the likelihood ratio test statistics, which is equivalent to a supremum statistics, could improve power over score tests. We generalize the likelihood ratio or supremum statistics to the semiparametric mixture model and demonstrate the power gain over the score …


Walking To Recovery - The Effects Of Postsurgical Ambulation On Patient Recovery Times, Trent William Stethen May 2016

Walking To Recovery - The Effects Of Postsurgical Ambulation On Patient Recovery Times, Trent William Stethen

Chancellor’s Honors Program Projects

No abstract provided.


Hpcnmf: A High-Performance Toolbox For Non-Negative Matrix Factorization, Karthik Devarajan, Guoli Wang Feb 2016

Hpcnmf: A High-Performance Toolbox For Non-Negative Matrix Factorization, Karthik Devarajan, Guoli Wang

COBRA Preprint Series

Non-negative matrix factorization (NMF) is a widely used machine learning algorithm for dimension reduction of large-scale data. It has found successful applications in a variety of fields such as computational biology, neuroscience, natural language processing, information retrieval, image processing and speech recognition. In bioinformatics, for example, it has been used to extract patterns and profiles from genomic and text-mining data as well as in protein sequence and structure analysis. While the scientific performance of NMF is very promising in dealing with high dimensional data sets and complex data structures, its computational cost is high and sometimes could be critical for …


Models For Hsv Shedding Must Account For Two Levels Of Overdispersion, Amalia Magaret Jan 2016

Models For Hsv Shedding Must Account For Two Levels Of Overdispersion, Amalia Magaret

UW Biostatistics Working Paper Series

We have frequently implemented crossover studies to evaluate new therapeutic interventions for genital herpes simplex virus infection. The outcome measured to assess the efficacy of interventions on herpes disease severity is the viral shedding rate, defined as the frequency of detection of HSV on the genital skin and mucosa. We performed a simulation study to ascertain whether our standard model, which we have used previously, was appropriately considering all the necessary features of the shedding data to provide correct inference. We simulated shedding data under our standard, validated assumptions and assessed the ability of 5 different models to reproduce the …