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Inter-Rater Reliability Of Statistics Based On Reconstructed Individual Patient Data From Published Kaplan-Meier Curves, Megan E. Smith
Inter-Rater Reliability Of Statistics Based On Reconstructed Individual Patient Data From Published Kaplan-Meier Curves, Megan E. Smith
Theses & Dissertations
Introduction: Time-to-event outcomes include two elements: an indicator variable for whether the event has taken place, and the length of time from some origin point to the occurrence of the event of interest. Due to the complexity of these data, secondary analysis methods, such as indirect comparisons and meta-analysis, are easier to perform when individual-level patient data (IPD) is available.
Objectives: In 2021, an R package IPDfromKM was published, which contains an algorithm for reconstructing IPD from a Kaplan-Meier graph. The current research aimed to investigate the reproducibility of the IPDfromKM algorithm.
Methods: Three statisticians (MS, LS, …