Biostatistics Commons^™

Age Dependent Analysis And Modeling Of Prostate Cancer Data, Nana Osei Mensa Bonsu

USF Tampa Graduate Theses and Dissertations

Growth rate of prostate cancer tumor is an important aspect of understanding the natural history of prostate cancer. Using real prostate cancer data from the SEER database with tumor size as a response variable, we have clustered the cancerous tumor sizes into age groups to enhance its analytical behavior. The rate of change of the response variable as a function of age is given for each cluster. Residual analysis attests to the quality of the analytical model and the subject estimates. In addition, we have identified the probability distribution that characterize the behavior of the response variable and proceeded with …

Multiple Calibrations In Integrative Data Analysis: A Simulation Study And Application To Multidimensional Family Therapy, Kristin Wynn Hall

USF Tampa Graduate Theses and Dissertations

A recent advancement in statistical methodology, Integrative Data Analyses (IDA Curran & Hussong, 2009) has led researchers to employ a calibration technique as to not violate an independence assumption. This technique uses a randomly selected, simplified correlational structured subset, or calibration, of a whole data set in a preliminary stage of analysis. However, a single calibration estimator suffers from instability, low precision and loss of power. To overcome this limitation, a multiple calibration (MC; Greenbaum et al., 2013; Wang et al., 2013) approach has been developed to produce better estimators, while still removing a level of dependency in the data …

Uncontrolled Hypertension And Associated Factors In Hypertensive Patients At The Primary Healthcare Center Luis H. Moreno, Panama: A Feasibility Study, Roderick Ramon Chen Camano

USF Tampa Graduate Theses and Dissertations

Background: According to the World Health Organization (WHO), hypertension is a major risk factor for cardiovascular disease (CVD), renal impairment, peripheral vascular disease, and blindness. In Panama, a recent study estimated the prevalence of hypertension at 38.5% in the two main provinces of the country, with a rate of uncontrolled hypertension of 47.2%.

Objectives: The aims of this study were to assess the feasibility of the study design and to describe the characteristics of the hypertensive population and the physician's adherence to Panamanian antihypertensive protocols and their relationship with uncontrolled hypertension.

Methods: This is a cross-sectional study of adult hypertensive …

A Latent Mixture Approach To Modeling Zero-Inflated Bivariate Ordinal Data, Rajendra Kadel

USF Tampa Graduate Theses and Dissertations

Multivariate ordinal response data, such as severity of pain, degree of disability, and satisfaction with a healthcare provider, are prevalent in many areas of research including public health, biomedical, and social science research. Ignoring the multivariate features of the response variables, that is, by not taking the correlation between the errors across models into account, may lead to substantially biased estimates and inference. In addition, such multivariate ordinal outcomes frequently exhibit a high percentage of zeros (zero inflation) at the lower end of the ordinal scales, as compared to what is expected under a multivariate ordinal distribution. Thus, zero inflation …

A Monte Carlo Approach To Change Point Detection In A Liver Transplant, Alexia Melissa Makris

USF Tampa Graduate Theses and Dissertations

Patient survival post liver transplant (LT) is important to both the patient and the center's accreditation, but over the years physicians have noticed that distant patients struggle with post LT care. I hypothesized that patient's distance from the transplant center had a detrimental effect on post LT survival. I suspected Hepatitis C (HCV) and Hepatocellular Carcinoma (HCC) patients would deteriorate due to their recurrent disease and there is a need for close monitoring post LT. From the current literature it was not clear if patients' distance from a transplant center affects outcomes post LT. Firozvi et al. (Firozvi AA, 2008) …