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Full-Text Articles in Biostatistics

Implementation Of Digital Health In Addressing Global Threats: Lessons From The Use Of Technology During Covid-19 Pandemic In Indonesia, Naili Shifa, Anisa Tiasari, Kemal N. Siregar Feb 2024

Implementation Of Digital Health In Addressing Global Threats: Lessons From The Use Of Technology During Covid-19 Pandemic In Indonesia, Naili Shifa, Anisa Tiasari, Kemal N. Siregar

Kesmas

This research conducted a systematic literature review to explore the implementation of digital health in Indonesia, focusing on the digital health policies, usage during the COVID-19 pandemic, benefits, and lessons learned. The study identified 10 relevant journals through database searches and analyzed the trends in publication, productive journals, and top institutions involved in digital health research. The findings revealed an increasing interest in digital health, with a growing number of published articles from 2021 to 2023. ScienceDirect emerged as the most productive journal, followed by PubMed and MDPI. The University of Indonesia and the University of Gajah Mada were the …


Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia Dec 2023

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …


Editorial: The Public Health Scholars As The Health Leaders, Al Asyary, Meita Veruswati, Putri Bungsu Machmud, Indri Hapsari Susilowati Nov 2023

Editorial: The Public Health Scholars As The Health Leaders, Al Asyary, Meita Veruswati, Putri Bungsu Machmud, Indri Hapsari Susilowati

Kesmas

No abstract provided.


The Prevalence Of Burnout In Saudi Arabia Dental Hygienists, Nouf Hamad Aldayel Oct 2023

The Prevalence Of Burnout In Saudi Arabia Dental Hygienists, Nouf Hamad Aldayel

Dental Hygiene Theses & Dissertations

Purpose: The purpose of this pilot study was to assess the prevalence of burnout in Saudi Arabian dental hygienists and identify risk factors associated with burnout. Methods: A descriptive survey design using the Copenhagen Burnout Inventory (CBI) assessed burnout among a convenience sample of n=123 Saudi dental hygienists. The survey was disseminated electronically to 1,000 Saudi Arabian dental hygienists. The CBI measures three subscales: personal, work-related, and client/patient-related burnout on a five-point Likert-type scale. The survey also included six demographic questions, two Likert-type, one “yes/no,” and one openended question, related to burnout. Descriptive statistics, one-way between subject’s ANOVA, independent samples …


Editorial, Al Asyary Jul 2023

Editorial, Al Asyary

Kesmas

No abstract provided.


Utilizing New Technologies To Measure Therapy Effectiveness For Mental And Physical Health, Jonathan Ossie May 2023

Utilizing New Technologies To Measure Therapy Effectiveness For Mental And Physical Health, Jonathan Ossie

Dissertations

Mental health is quickly becoming a major policy concern, with recent data reporting increasing and disproportionately worse mental health outcomes, including anxiety, depression, increased substance abuse, and elevated suicidal ideation. One specific population that is especially high risk for these issues is the military community because military conflict, deployment stressors, and combat exposure contribute to the risk of mental health problems.

Although several pharmacological approaches have been employed to combat this epidemic, their efficacy is mixed at best, which has led to novel nonpharmacological approaches. One such approach is Operation Surf, a nonprofit that provides nature-based programs advocating the restorative …


Community Participation And Perspectives Of Ambondrolava Mangrove Restoration Project, Nadine Shannon Apr 2023

Community Participation And Perspectives Of Ambondrolava Mangrove Restoration Project, Nadine Shannon

Independent Study Project (ISP) Collection

Madagascar’s mangrove forests are intertidal ecosystems that provide numerous valuable ecosystem services but are nonetheless under pressure from large amounts of deforestation. On the southwestern coast of Madagascar, the village of Ambondrolava practices community led management of the mangrove and its resources. This research project studied the evolution of the mangrove area using GIS data, and investigated, through interviews, the relationship between the local community of Ambondrolava and the organizations that manage the mangrove ecosystem. From 2000 to 2018, the zone of the mangrove has experienced a net loss in area every year, despite reforestation efforts. Most community members interviewed …


Vibrio Cholerae In Rural And Urban Bangladesh, Findings From Hospital-Based Surveillance, 2000–2021, Rina Das, Sabiha Nasrin, Parag Palit, Rukaeya Amin Sobi, Al-Afroza Sultana, Soroar Hossain Khan, Md. Ahshanul Haque, Sharika Nuzhat, Tahmeed Ahmed, A. S. G. Faruque, Mohammod Jobayer Chisti Jan 2023

Vibrio Cholerae In Rural And Urban Bangladesh, Findings From Hospital-Based Surveillance, 2000–2021, Rina Das, Sabiha Nasrin, Parag Palit, Rukaeya Amin Sobi, Al-Afroza Sultana, Soroar Hossain Khan, Md. Ahshanul Haque, Sharika Nuzhat, Tahmeed Ahmed, A. S. G. Faruque, Mohammod Jobayer Chisti

Biostatistics and Epidemiology Faculty Publications Series

With more than 100,000 cases estimated each year, Bangladesh is one of the countries with the highest number of people at risk for cholera. Moreover, Bangladesh is formulating a countrywide cholera-control plan to satisfy the GTFCC (The Global Task Force on Cholera Control) Roadmap's goals. With a particular focus on cholera trends, variance in baseline and clinical characteristics of cholera cases, and trends in antibiotic susceptibility among clinical isolates of Vibrio cholerae, we used data from facility-based surveillance systems from icddr,b’s Dhaka, and Matlab Hospitals from years 2000 to 2021. Female patients comprised 3,553 (43%) in urban and 1,099 (51.6%) …


A Cross-Ancestry Genome-Wide Meta-Analysis, Fine-Mapping, And Gene Prioritization Approach To Characterize The Genetic Architecture Of Adiponectin, Casssandra N. Spracklen, Et. Al. Jan 2023

A Cross-Ancestry Genome-Wide Meta-Analysis, Fine-Mapping, And Gene Prioritization Approach To Characterize The Genetic Architecture Of Adiponectin, Casssandra N. Spracklen, Et. Al.

Biostatistics and Epidemiology Faculty Publications Series

No abstract provided.


Childhood And Adulthood Passive And Active Smoking, And The Abo Group As Risk Factors For Pancreatic Cancer In Women, Anne-Laure Vedie, Nasser Laouali, Amandine Gelot, Gianluca Severi, Marie-Christine Boutron-Ruault, Vinciane Rebours Jan 2023

Childhood And Adulthood Passive And Active Smoking, And The Abo Group As Risk Factors For Pancreatic Cancer In Women, Anne-Laure Vedie, Nasser Laouali, Amandine Gelot, Gianluca Severi, Marie-Christine Boutron-Ruault, Vinciane Rebours

Biostatistics and Epidemiology Faculty Publications Series

Objectives

Active smoking and the A blood group are associated with pancreatic adenocarcinoma (PC) risk. However, potential interactions between those risk factors and the role of passive smoking have been little investigated. We aimed to explore specific and joint associations of passive and active smoking, and effect modification by the ABO blood group in French women.

Methods

The study included 96,594 women from the E3N prospective cohort, mean age: 49 years (SD 6.7). Information on active and passive smoking was reported at inclusion and throughout follow-up. Cases were classified according to the International Classification of Diseases 10. Associations with passive …


Comparison Of Combination Methods To Create Calibrated Ensemble Forecasts For Seasonal Influenza In The U.S., Nutcha Wattanachit, Evan L. Ray, Thomas C. Mcandrew, Nicholas G. Reich Jan 2023

Comparison Of Combination Methods To Create Calibrated Ensemble Forecasts For Seasonal Influenza In The U.S., Nutcha Wattanachit, Evan L. Ray, Thomas C. Mcandrew, Nicholas G. Reich

Biostatistics and Epidemiology Faculty Publications Series

The characteristics of influenza seasons vary substantially from year to year, posing challenges for public health preparation and response. Influenza forecasting is used to inform seasonal outbreak response, which can in turn potentially reduce the impact of an epidemic. The United States Centers for Disease Control and Prevention, in collaboration with external researchers, has run an annual prospective influenza forecasting exercise, known as the FluSight challenge. Uniting theoretical results from the forecasting literature with domain-specific forecasts from influenza outbreaks, we applied parametric forecast combination methods that simultaneously optimize model weights and calibrate the ensemble via a beta transformation and made …


Metabolic Alterations And Cardiovascular Risk After Hepatitis C Cure In Subjects With Or At Risk For Hiv, Christophe Maxime Fokoua Dongmo Dec 2022

Metabolic Alterations And Cardiovascular Risk After Hepatitis C Cure In Subjects With Or At Risk For Hiv, Christophe Maxime Fokoua Dongmo

Legacy Theses & Dissertations (2009 - 2024)

Background. Hepatitis C virus (HCV) infection engenders substantial metabolic changes. These changes are altered when the virus is cleared after successful treatment. We measured these metabolic alterations that occur after HCV cure; further, we assessed whether these alterations differed in subgroups defined by patients’ characteristics.


The Potential Of Private Health Insurance Ownership Based On The 2018-2020 National Socioeconomic Survey Data, Arief Rosyid Hasan, Adang Bachtiar, Cicilya Candi Nov 2022

The Potential Of Private Health Insurance Ownership Based On The 2018-2020 National Socioeconomic Survey Data, Arief Rosyid Hasan, Adang Bachtiar, Cicilya Candi

Kesmas

In 2014, the Indonesian Government introduced a social security program in the health sector. However, Indonesia’s out-of-pocket expenses remain high due to a lack of public interest in National Health Insurance services. Financing expensive health services with high out-of-pocket expenses has the potential to cause poverty. Private health insurance is considered a solution to this problem. This study aimed to determine the socioeconomic factors of private health insurance ownership and its potential in Indonesia. This study used secondary data from the 2018, 2019, and 2020 National Socioeconomic Surveys. Logistic regression analysis showed that the variables related to private health insurance …


Pandemic Fatigue Impedes Mitigation Of Covid-19 In Hong Kong, Zhanwei Du, Lin Wang, Songwei Shan, Dickson Lam, Tim K. Tsang, Jingyi Xiao, Huizhi Gao, Bingyi Yang, Sheikh Taslim Ali, Sen Pei, Isaac Chun-Hai Fung, Eric H. Y. Lau, Qiuyan Liao, Peng Wu, Lauren Ancel Meyers, Gabriel M. Leung, Benjamin Cowling Nov 2022

Pandemic Fatigue Impedes Mitigation Of Covid-19 In Hong Kong, Zhanwei Du, Lin Wang, Songwei Shan, Dickson Lam, Tim K. Tsang, Jingyi Xiao, Huizhi Gao, Bingyi Yang, Sheikh Taslim Ali, Sen Pei, Isaac Chun-Hai Fung, Eric H. Y. Lau, Qiuyan Liao, Peng Wu, Lauren Ancel Meyers, Gabriel M. Leung, Benjamin Cowling

Department of Biostatistics, Epidemiology, and Environmental Health Sciences Faculty Publications

Hong Kong has implemented stringent public health and social measures (PHSMs) to curb each of the four COVID-19 epidemic waves since January 2020. The third wave between July and September 2020 was brought under control within 2 m, while the fourth wave starting from the end of October 2020 has taken longer to bring under control and lasted at least 5 mo. Here, we report the pandemic fatigue as one of the potential reasons for the reduced impact of PHSMs on transmission in the fourth wave. We contacted either 500 or 1,000 local residents through weekly random-digit dialing of landlines …


Multi-Trophic Biodiversity Increases With Increasing Structural Complexity Of Forest Canopy, Ayanna St. Rose May 2022

Multi-Trophic Biodiversity Increases With Increasing Structural Complexity Of Forest Canopy, Ayanna St. Rose

Graduate Theses and Dissertations

Understanding the effects of forest canopy structural complexity on multi-trophic diversity is critical for conserving biodiversity and managing land sustainably. But multi-trophic diversity is often ignored when making decisions about land management due to lack of cost- and time-effective methods to evaluate it. Here, we explored a new method based on widely available remote sensing data to quantify canopy structural complexity and its relationships with multi-trophic biodiversity at landscape scale using 32 forested sites of the National Ecological Observatory Network. We investigated the influence of vertical and horizontal structural complexity of forest canopy on multi-trophic (primary producers, herbivores (beetles), omnivores …


Length Of Stay In A Homeless Shelter And Mitigating Homelessness, Uwemedimo S. Etteyit Jan 2022

Length Of Stay In A Homeless Shelter And Mitigating Homelessness, Uwemedimo S. Etteyit

Walden Dissertations and Doctoral Studies

AbstractHomelessness is a major public health issue in the United States. Every night, thousands of people have no residence to call their own. Most homeless persons turn to homeless shelters for help. Despite the homeless shelters, the problem of homelessness persists. This study examined the concept that the length of time spent at a homeless shelter is related to the homeless persons mitigating their homelessness through home placement, jobs, and healthcare access. Homelessness was examined using the socioecological model with its attendant levels of influence. On the intrapersonal level, socioeconomic status, education, old age, veteran status, and disability were factors. …


Monitoring Mammals At Multiple Scales: Case Studies From Carnivore Communities, Kadambari Devarajan Oct 2021

Monitoring Mammals At Multiple Scales: Case Studies From Carnivore Communities, Kadambari Devarajan

Doctoral Dissertations

Carnivores are distributed widely and threatened by habitat loss, poaching, climate change, and disease. They are considered integral to ecosystem function through their direct and indirect interactions with species at different trophic levels. Given the importance of carnivores, it is of high conservation priority to understand the processes driving carnivore assemblages in different systems. It is thus essential to determine the abiotic and biotic drivers of carnivore community composition at different spatial scales and address the following questions: (i) What factors influence carnivore community composition and diversity? (ii) How do the factors influencing carnivore communities vary across spatial and temporal …


A Biological Assessment Of Water Quality In El Placer, Ecuador: The Effect Of Agriculture On Stream Health And The Quality Of Historical Versus Current Drinking Water Sources, Danielle Kleinberg Oct 2021

A Biological Assessment Of Water Quality In El Placer, Ecuador: The Effect Of Agriculture On Stream Health And The Quality Of Historical Versus Current Drinking Water Sources, Danielle Kleinberg

Independent Study Project (ISP) Collection

Although fresh water is one of Ecuador’s most abundant resources, high quality drinking water for its inhabitants is scarce (Wingfield et al., 2021). The most prevalent sources of water pollution in Ecuador are domestic waste, silver and gold mining, oil production, and agricultural chemicals (Buckalew et al., 1997). El Placer, a village located in Tungurahua, Ecuador, is highly dependent on agriculture as a source of income. The first objective of this study was to determine the effect of agriculture on the El Placer’s Tía Anita Stream through comparing the water quality at three sites with varying agricultural influence. The second …


Ecological Risk Assessment For The Temperate Demersal Elasmobranch Resource, Department Of Primary Industries And Regional Development, Western Australia Oct 2021

Ecological Risk Assessment For The Temperate Demersal Elasmobranch Resource, Department Of Primary Industries And Regional Development, Western Australia

Fisheries research reports

No abstract provided.


2021 Assessment Of The Status Of The West Coast Demersal Scalefish Resource, David V. Fairclough, Sybrand Alex Hesp, Ainslie Denham, Emily A. Fisher, Rachel Marks, Karina L. Ryan, Elaine Lek, Rhys Allen, Brett M. Crisafulli Oct 2021

2021 Assessment Of The Status Of The West Coast Demersal Scalefish Resource, David V. Fairclough, Sybrand Alex Hesp, Ainslie Denham, Emily A. Fisher, Rachel Marks, Karina L. Ryan, Elaine Lek, Rhys Allen, Brett M. Crisafulli

Fisheries research reports

A recovery program for the West Coast Demersal Scalefish Resource was introduced between late 2007 and early 2010, based on the maintenance of retained catches of demersal species (overall suite and each indicator species) by both the commercial and recreational sectors below 50% of the catches reported in 2005/06 (original catch recovery benchmarks).

Catch reductions were aimed at reducing exploitation levels (F, long-term fishing mortality of the key indicator species’ stocks) to below the threshold reference point (F = M, the natural mortality rate), which would then allow stocks to recover to above the …


Squid And Cuttlefish Resources Of Western Australia, Daniel Yeoh, Danielle J. Johnston Phd, David C. Harris Sep 2021

Squid And Cuttlefish Resources Of Western Australia, Daniel Yeoh, Danielle J. Johnston Phd, David C. Harris

Fisheries research reports

No abstract provided.


Otoliths Of South-Western Australian Fish: A Photographic Catalogue, Chris Dowling, Kim Smith, Elain Lek, Joshua Brown Sep 2021

Otoliths Of South-Western Australian Fish: A Photographic Catalogue, Chris Dowling, Kim Smith, Elain Lek, Joshua Brown

Fisheries research reports

No abstract provided.


Anti-Vaxxers: Parents Fighting Science, Katie West Aug 2021

Anti-Vaxxers: Parents Fighting Science, Katie West

Symposium of Student Scholars

Immunizing children helps protect the health of our community, especially those people who cannot be immunized. Yet, since 1996 after a study was released that linked autism to vaccinations, there has been a trend of parents refusing to vaccinate their children. What are the demographics of the parents who believe their children are better off without vaccines? By knowing where these parents live and what decisions they make for their children’s education, counties and medical professionals can provide education and address their concerns.

My research involves data on 116,141 kindergarten classes from 2000-2015 in California. The two vaccine exemption options …


Effect Sizes And Intra-Cluster Correlation Coefficients Measured From The Green Dot High School Study For Guiding Sample Size Calculations When Designing Future Violence Prevention Cluster Randomized Trials In School Settings, Md. Tofial Azam, Heather M. Bush, Ann L. Coker, Philip M. Westgate Aug 2021

Effect Sizes And Intra-Cluster Correlation Coefficients Measured From The Green Dot High School Study For Guiding Sample Size Calculations When Designing Future Violence Prevention Cluster Randomized Trials In School Settings, Md. Tofial Azam, Heather M. Bush, Ann L. Coker, Philip M. Westgate

Biostatistics Faculty Publications

Purpose: Cluster randomized controlled trials (cRCTs) are popular in school-based research designs where schools are randomized to different trial arms. To help guide future study planning, we provide information on anticipated effect sizes and intra-cluster correlation coefficients (ICCs), as well as school sizes, for dating violence (DV) and interpersonal violence outcomes based on data from a cRCT which evaluated the bystander-based violence intervention ‘Green Dot’.

Methods: We utilized data from 25 schools from the Green Dot High School study. Effect size and ICC values corresponding to dating and interpersonal violence outcomes are obtained from linear mixed effect models. We …


Pattern Of Use Of Electronic Health Record (Ehr) Among The Chronically Ill: A Health Information National Trend Survey (Hints) Analysis, Rose Calixte, Sumaiya Islam, Zainab Toteh Osakwe, Argelis Rivera, Marlene Camacho-Rivera Jul 2021

Pattern Of Use Of Electronic Health Record (Ehr) Among The Chronically Ill: A Health Information National Trend Survey (Hints) Analysis, Rose Calixte, Sumaiya Islam, Zainab Toteh Osakwe, Argelis Rivera, Marlene Camacho-Rivera

Publications and Research

Effective patient–provider communication is a cornerstone of patient-centered care. Patient portals provide an effective method for secure communication between patients or their proxies and their health care providers. With greater acceptability of patient portals in private practices, patients have a unique opportunity to manage their health care needs. However, studies have shown that less than 50% of patients reported accessing the electronic health record (EHR) in a 12-month period. We used HINTS 5 cycle 1 and cycle 2 to assess disparities among US residents 18 and older with any chronic condition regarding the use of EHR for secure direct messaging …


Evaluating Public Masking Mandates On Covid-19 Growth Rates In U.S. States, Angus K. Wong Jul 2021

Evaluating Public Masking Mandates On Covid-19 Growth Rates In U.S. States, Angus K. Wong

Masters Theses

U.S. state governments have implemented numerous policies to help mitigate the spread of COVID-19. While there is strong biological evidence supporting the wearing of face masks or coverings in public spaces, the impact of public masking policies remains unclear. We aimed to evaluate how early versus delayed implementation of state-level public masking orders impacted subsequent COVID-19 growth rates. We defined “early” implementation as having a state-level mandate in place before September 1, 2020, the approximate start of the school-year. We defined COVID-19 growth rates as the relative increase in confirmed cases 7, 14, 21, 30, 45, 60-days after September 1. …


Taxonomic Annotation Of Near-Coral Seawater Microbiota In Kilifi, Kenya, Megan Ruoff Apr 2021

Taxonomic Annotation Of Near-Coral Seawater Microbiota In Kilifi, Kenya, Megan Ruoff

Independent Study Project (ISP) Collection

The general objective of this study was to analyze the microbiome of seawater above a coral reef in Kilifi, Kenya. Specific objectives included establishing a baseline microbiota profile, classifying the identified organisms at various taxonomic levels, and conjecturing about reef health from the presence or absence of bioindicator species including Vibrio bacteria. Sequenced 16S rRNA gene sequences from seawater samples at Kuruwitu Conservancy in Kilifi, Kenya were taxonomically classified by exact matching employing the Dada2 software package and the naïve Bayesian classifier method with 97% similarity cut off. The seawater microbiota contained mostly Proteobacteria (73.28%), followed by Bacteroidetes (14.08%) and …


An Assessment Of Terrestrial Decapoda Diversity Across Three Ecological Zones In Mida Creek, Kenya, Reese Yount Apr 2021

An Assessment Of Terrestrial Decapoda Diversity Across Three Ecological Zones In Mida Creek, Kenya, Reese Yount

Independent Study Project (ISP) Collection

Mangroves make up one of the most effective natural remedies at combating climate change today. They represent great commercial interest worldwide and yet, are being degraded at an unsustainable rate. If successful mangrove conservation plans are to be implemented for our posterity, mangrove ecosystems need to be better understood at the community level. Mangrove crabs make up the most diverse and populace mangrove inhabitants. They are classified as ecosystem engineers and their potential for being used as bioindicators makes them integral to assessing mangrove health. Yet, their diversity and distribution patterns are not well understood. The aim of this study …


Mental Health And Psychosocial Functioning In Recently Separated U.S. Women Veterans: Trajectories And Bi-Directional Relationships, Karen A. Lawrence, Dawne Vogt, Adam Dugan, Shawn R. Nigam, Emily Slade, Brian N. Smith Jan 2021

Mental Health And Psychosocial Functioning In Recently Separated U.S. Women Veterans: Trajectories And Bi-Directional Relationships, Karen A. Lawrence, Dawne Vogt, Adam Dugan, Shawn R. Nigam, Emily Slade, Brian N. Smith

Social Work Faculty Publications

Prior research on the relationship between veterans’ mental health and psychosocial functioning has primarily relied on male samples. Here, we investigated prospective longitudinal relationships between mental health and psychosocial functioning in 554 female Iraq and Afghanistan War veterans who were surveyed three times between two- and seven-years following separation from service. Mixed effects modeling revealed that increasing depression and posttraumatic stress disorder (PTSD) severity predicted declines in work functioning. Increasing PTSD severity predicted declining parental functioning and worsening depression predicted a decline in relationship functioning. In turn, decreased work and intimate relationship functioning predicted increased PTSD and depression symptom severity …


Per- And Polyfluoroalkyl Substances And Kidney Function: Follow-Up Results From The Diabetes Prevention Program Trial, Pi-I D. Lin, Andres Cardenas, Russ Hauser, Diane R. Gold, Ken P. Kleinman, Marie-France Hivert, Antonia M. Calafat, Thomas F. Webster, Edward S. Horton, Emily Oken Jan 2021

Per- And Polyfluoroalkyl Substances And Kidney Function: Follow-Up Results From The Diabetes Prevention Program Trial, Pi-I D. Lin, Andres Cardenas, Russ Hauser, Diane R. Gold, Ken P. Kleinman, Marie-France Hivert, Antonia M. Calafat, Thomas F. Webster, Edward S. Horton, Emily Oken

Biostatistics and Epidemiology Faculty Publications Series

Per- and polyfluoroalkyl substances (PFAS) are ubiquitously detected in populations worldwide and may hinder kidney function. The objective of the study was to determine longitudinal associations of plasma PFAS concentrations with estimated glomerular filtration rate (eGFR) and evaluate whether a lifestyle intervention modify the associations. We studied 875 participants initially randomized to the lifestyle or placebo arms in the Diabetes Prevention Program (DPP, 1996–2002) trial and Outcomes Study (DPPOS, 2002–2014). We ran generalized linear mixed models accounting a priori covariates to evaluate the associations between baseline PFAS concentrations and repeated measures of eGFR, separately, for six PFAS (PFOS, PFOA, PFHxS, …