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Full-Text Articles in Biostatistics
The Morbidity & Mortality Of Prevalent Heart Failure, Jennifer Kwon
The Morbidity & Mortality Of Prevalent Heart Failure, Jennifer Kwon
Loma Linda University Electronic Theses, Dissertations & Projects
The first study population included 292 unselected consecutive patients from the LLUMC heart failure clinic who were enrolled in the study from January to July 2006 and were followed up through the end of December 2010. The treatment policy at the clinic was to uptitrate dosages of beta-adrenergic blockade (β-blockers), angiotensin-converting-enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) to the most tolerable levels in order to reach target dosages, as recommended by the Heart Failure Society of America (HFSA). Patients were classified into systolic heart failure (ejection fraction (EF) < 40%) or diastolic heart failure (EF≥40%). All dosages of β-blockers, ACEi and ARB were extracted through chart reviews and were used as the main predictors of the patients' survival. Results from analyses showed that reaching target dosages of β-blockers and ACEi/ARB may increase survival when compared to not reaching target among the systolic HF population (HRβ_biockers= 0.64, 95% CI 0.26-1.56 and HRACEi/ARB=0.50, …
Body Weight And Mortality Among Adults Who Never Smoked, Pramil N. Singh
Body Weight And Mortality Among Adults Who Never Smoked, Pramil N. Singh
Loma Linda University Electronic Theses, Dissertations & Projects
Most prospective studies identify an increased mortality risk for adults of high body mass index (> 27 kg/m2) that is commonly attributed to the effects of excess body fat, and also identify an increased mortality risk for adults of low body mass index (< 21 kg/m2), an association that, if causal among healthy adults, is without adequate pathophysiologic support.
In this dissertation, I have conducted three studies that continue the investigation of adiposity in relation to mortality among never-smoking adults of the California Seventh-day Adventist population. Among never-smoking adults of the Adventist Mortality Study (1960-1985), the relation between …
Models For Estimating Psychiatric Bed Needs, Patricia A. Brenneman
Models For Estimating Psychiatric Bed Needs, Patricia A. Brenneman
Loma Linda University Electronic Theses, Dissertations & Projects
Inland Counties Comprehensive Health Planning Council wished to estimate the psychiatric bed needs by type (such as state hospitals, board and care homes, etc.) in San Bernardino County from the distributions of patient arrivals and of lengths of stay. A statistical description of the system during 1973 was considered the first step toward estimating future bed needs. A computer simulation model using IBM's programming language General Purpose Simulation System (GPSS) was developed and was found to be unsatisfactory.
Theorems were then developed for a statistical model, seeking to predict future bed needs. The most convenient of these theorems states that …