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Full-Text Articles in Biostatistics
Regression Modeling Of Complex Survival Data Based On Pseudo-Observations, Rong Rong
Regression Modeling Of Complex Survival Data Based On Pseudo-Observations, Rong Rong
Statistical Science Theses and Dissertations
The restricted mean survival time (RMST) is a clinically meaningful summary measure in studies with survival outcomes. Statistical methods have been developed for regression analysis of RMST to investigate impacts of covariates on RMST, which is a useful alternative to the Cox regression analysis. However, existing methods for regression modeling of RMST are not applicable to left-truncated right-censored data that arise frequently in prevalent cohort studies, for which the sampling bias due to left truncation and informative censoring induced by the prevalent sampling scheme must be properly addressed. Meanwhile, statistical methods have been developed for regression modeling of the cumulative …