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Full-Text Articles in Biometry

(R2174) A Stationary First-Order Autoregressive Process With New Discrete Lindley Marginal Distribution, Tégawendé Martin Kabore, Jean-Etienne Ouindllassida Ouédraogo Jun 2026

(R2174) A Stationary First-Order Autoregressive Process With New Discrete Lindley Marginal Distribution, Tégawendé Martin Kabore, Jean-Etienne Ouindllassida Ouédraogo

Applications and Applied Mathematics: An International Journal (AAM)

This paper introduces a new stationary first-order autoregressive integer-valued process with a marginal distribution following the New Discrete Lindley distribution, referred to as NDLINAR( 1). The process is developed to model over-dispersed count time series exhibiting a mixed behavior arising from the combination of multiple distributions. Its statistical properties are thoroughly investigated, and the parameters are estimated using conditional maximum likelihood. The asymptotic properties of the estimators are also analyzed. The performance of the proposed model is evaluated by comparing it with other existing INAR(1) processes through applications to real datasets. Results demonstrate that the NDL-INAR(1) process effectively captures the …


“Regression To The Mean”: The Confluence Of Eugenics And Statistics In The 19th And 20th Centuries, Emrys G. King Jan 2025

“Regression To The Mean”: The Confluence Of Eugenics And Statistics In The 19th And 20th Centuries, Emrys G. King

Pomona Senior Theses

The work of this thesis is twofold — first, qualitatively characterizing the confluence between the British eugenics and statistics movements in the late 19th and early 20th centuries, and second, quantitatively analyzing the effect of this foundation on pedagogical materials in the growing field of statistics between 1880 and 1970. Towards the first goal, the history of the method of least squares, state statistics, and positive and negative eugenics are outlined, followed by a close reading of the foundational texts authored by Francis Galton and Karl Pearson that introduced linear regression. Towards the latter goal, English-language statistics textbooks published between …


Unified Methods For Feature Selection In Large-Scale Genomic Studies With Censored Survival Outcomes, Lauren Spirko-Burns, Karthik Devarajan Mar 2019

Unified Methods For Feature Selection In Large-Scale Genomic Studies With Censored Survival Outcomes, Lauren Spirko-Burns, Karthik Devarajan

COBRA Preprint Series

One of the major goals in large-scale genomic studies is to identify genes with a prognostic impact on time-to-event outcomes which provide insight into the disease's process. With rapid developments in high-throughput genomic technologies in the past two decades, the scientific community is able to monitor the expression levels of tens of thousands of genes and proteins resulting in enormous data sets where the number of genomic features is far greater than the number of subjects. Methods based on univariate Cox regression are often used to select genomic features related to survival outcome; however, the Cox model assumes proportional hazards …


Models For Hsv Shedding Must Account For Two Levels Of Overdispersion, Amalia Magaret Jan 2016

Models For Hsv Shedding Must Account For Two Levels Of Overdispersion, Amalia Magaret

UW Biostatistics Working Paper Series

We have frequently implemented crossover studies to evaluate new therapeutic interventions for genital herpes simplex virus infection. The outcome measured to assess the efficacy of interventions on herpes disease severity is the viral shedding rate, defined as the frequency of detection of HSV on the genital skin and mucosa. We performed a simulation study to ascertain whether our standard model, which we have used previously, was appropriately considering all the necessary features of the shedding data to provide correct inference. We simulated shedding data under our standard, validated assumptions and assessed the ability of 5 different models to reproduce the …