Statistics and Probability Commons^™

Determining The Ideal Concentrations Of Ethanol And Propylene Glycol In Ethosomes For Transdermal Delivery Of Vitamin D3, Rebecca Conner

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Vitamin D₃ is an important chemical in the human body, however, many Americans have low levels of this vitamin. There are plenty of oral supplementations for Vitamin D₃ deficiency, but those of older age and busy schedules may struggle to meet the minimum requirement. A recently developed ethosomal transmembrane delivery system (Touitou, 2000), similar to liposomes but also containing ethanol, allows users to apply a gel dermally and have the desired drug or active ingredient reach the bloodstream faster. However, there is considerable variation in the concentration of ethanol and permeation enhancers used. Using an affordable method to …

Would You Choose The Same Nationality If You Were Born Again?, Keito Kono, Logan Bowerman

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Nationality is an important element in the formation of identity, but this brings up a question; that is whether people are proud of their nationality. Thus, we decided to investigate how many people would prefer to have the same nationality if they were born again. This survey is important because it could provide an opportunity to recognize people's interest in other countries and their patriotism

The Relationship Between Pets Owned And Gender Amongst College Students, Eman Asghar, Bryce Camuso, Josh Feirick

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

There is a gap between the number of men and women that own dogs. The Mintel Press Team states that "71% of men aged 18-44 own a dog compared to 60% of their female counterparts" (Mintel Press Team, 2016, para: 1). While this statistic includes people who are college-aged, it does not mention college students specifically. Thus, research into the relationship between pets owned and gender amongst college students is an important topic that warrants looking into.

The Knowledge Of One's Blood Type, Mackenzie Degroft, Ethan Hall, Scarlet Morillo

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

An experiment of sample surveys of undergraduate students' knowledge of their blood type.

A Statistical Study Into The Number Of Hours Students At Harrisburg University Spend On Social Media, Nabeel Hakeem-Olowu, Samantha Weaver, Kyla Lea

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

The aim of the study is to examine the number of hours that Harrisburg University students spent on social media during their spare time. The purpose of the study is to raise awareness among students about the possible negative impacts of excessive social media usage on their academic performance, social interactions, and sleep duration. Additionally, the study explored the relationship between social media use and academic performance. To collect data, we surveyed one hundred and fifty students from Harrisburg University. The survey consisted of questions related to the number of hours spent on social media during spare time. The respondents …

Data Sharing And Ontology Use Among Agricultural Genetics, Genomics, And Breeding Databases And Resources Of The Agbiodata Consortium, Jennifer L. Clarke, Laurel D. Cooper, Monica F. Poelchau, Tanya Z. Berardini, Justin Elser, Andrew D. Farmer, Stephen Ficklin, Sunita Kumari, Marie-Angélique Laporte, Rex T. Nelson, Rie Sadohara, Peter Selby, Anne E. Thessen, Brandon Whitehead, Taner Z. Sen

Department of Statistics: Faculty Publications

Over the last couple of decades, there has been a rapid growth in the number and scope of agricultural genetics, genomics and breeding databases and resources. The AgBioData Consortium (https://www.agbiodata.org/) currently represents 44 databases and resources (https://www.agbiodata.org/databases) covering model or crop plant and animal GGB data, ontologies, pathways, genetic variation and breeding platforms (referred to as ‘databases’ throughout). One of the goals of the Consortium is to facilitate FAIR (Findable, Accessible, Interoperable, and Reusable) data management and the integration of datasets which requires data sharing, along with structured vocabularies and/or ontologies. Two AgBioData working groups, focused on Data Sharing and …

Repurposing The Fda-Approved Anthelmintic Pyrvinium Pamoate For Pancreatic Cancer Treatment: Study Protocol For A Phase I Clinical Trial In Early-Stage Pancreatic Ductal Adenocarcinoma, Francesca M. Ponzini, Christopher W. Schultz, Benjamin E. Leiby, Shawnna Cannaday, T. Yeo, James Posey, Wilbur B. Bowne, Charles Yeo, Jonathan R. Brody, Harish Lavu, Avinoam Nevler

Department of Surgery Faculty Papers

BACKGROUND: Recent reports of the utilisation of pyrvinium pamoate (PP), an FDA-approved anti-helminth, have shown that it inhibits pancreatic ductal adenocarcinoma (PDAC) cell growth and proliferation in-vitro and in-vivo in preclinical models. Here, we report about an ongoing phase I open-label, single-arm, dose escalation clinical trial to determine the safety and tolerability of PP in PDAC surgical candidates.

METHODS AND ANALYSIS: In a 3+3 dose design, PP is initiated 3 days prior to surgery. The first three patients will be treated with the initial dose of PP at 5 mg/kg orally for 3 days prior to surgery. Dose doubling will …

Assessment Of First-Phase Covid-19 Pandemic In Europe Using Hierarchical Clustering Based On Principal Components Analysis, Sanjay Kumar, Evrim Oral

School of Public Health Faculty Publications

It is of great interest for researchers to assess the COVID-19 pandemic in Europe. Grouping of COVID-19-affected regions is an effective way to monitor and optimize planning to combat the disease. This paper applied hierarchical clustering based on principal components analysis (HCPCA) to COVID-19 data from affected European countries. Considering several attribute indices, we obtained a new set of indicators using principal components analysis to aggregate and reduce the dimension of attribute indices of affected countries. Further, we obtained groups of affected countries subject to their similarity using hierarchical clustering to the reduced observations of new attributes indices of these …

Exploring Parameter Sensitivity Analysis In Mathematical Modeling With Ordinary Differential Equations, Viktoria Savatorova

CODEE Journal

This paper presents an exploration into parameter sensitivity analysis in mathematical modeling using ordinary differential equations (ODEs). Taking the first steps in understanding local sensitivity analysis through the direct differential method and global sensitivity analysis using metrics like Pearson, Spearman, PRCC, and Sobol’, we provide readers with a basic understanding of parameter sensitivity analysis for mathematical modeling using ODEs. As an illustrative application, the system of differential equations modeling population dynamics of several fish species with harvest considerations is utilized. The results of employing local and global sensitivity analysis are compared, shedding light on the strengths and limitations of each …

Deep Q-Learning Framework For Quantitative Climate Change Adaptation Policy For Florida Road Network Due To Extreme Precipitation, Orhun Aydin

I-GUIDE Forum

Climate change-induced extreme weather and increasing population are increasing the pressure on the global aging road networks. Adaptation requires designing interventions and alterations to the road networks that consider future dynamics of flooding and increased traffic due to the growing population. This paper introduces a reinforcement learning approach to designing interventions for Florida's road network under future traffic and climate projections. Three climate models and a tide and surge model are used to create flooding and coastal inundation projections, respectively. The optimal sequence of decisions for adapting Florida's road network to minimize flooding-related disruptions is solved by using a graph-based …

Reducing Uncertainty In Sea-Level Rise Prediction: A Spatial-Variability-Aware Approach, Subhankar Ghosh, Shuai An, Arun Sharma, Jayant Gupta, Shashi Shekhar, Aneesh Subramanian

I-GUIDE Forum

Given multi-model ensemble climate projections, the goal is to accurately and reliably predict future sea-level rise while lowering the uncertainty. This problem is important because sea-level rise affects millions of people in coastal communities and beyond due to climate change's impacts on polar ice sheets and the ocean. This problem is challenging due to spatial variability and unknowns such as possible tipping points (e.g., collapse of Greenland or West Antarctic ice-shelf), climate feedback loops (e.g., clouds, permafrost thawing), future policy decisions, and human actions. Most existing climate modeling approaches use the same set of weights globally, during either regression or …

A Classical Fall Statistics Problem, Timothy Meyer

Cornhusker Economics

An evaluation of traditional baseball measures and suggestions for alternatives, centering on statistics related to the offensive quality of a player.

Es/Ph/Ra 626: Statistical Analysis I, Paul D. Loprinzi Ph.D.

GMAS Course Syllabi

No abstract provided.

Math 575: Mathematical Statistics I, Xin Dang

GMAS Course Syllabi

No abstract provided.

Academic Evaluation From The Perspective Of Multi-Source Eterogeneous Data:Connotation, Status And Prospect, Sanhong Deng, Jie Yang, Hao Wang, Jia Shen

Journal of Scientific Information Research

[Purpose/significance]Academic evaluation and scientometric methods of synthesizing multisource heterogeneous data have gradually become hot spots in the field. At present， there is no systematic theoretical discussion on academic evaluation from the perspective of multisource heterogeneous data.[Method/process]In view of insufficient utilization of multi-source heterogeneous data， inappropriate research methods， and unclear research objectives， this paper combs the development of academic evaluation from the perspective of multi-source heterogeneous data， and clarifies the connotation and extension of the field， and analyzes the frontiers and hot spots in the field.[Result/conclusion]The results state clearly that from the perspective of multi-source heterogeneous data， academic evaluation manifests the …

Beyond 365 Days: A Retrospective Evaluation Of Trekkers, Sarah Krichels Goan Mpp, Madison Burke

Publications

The Trekkers program in Rockland, ME is a non-profit outdoor-based mentoring program that has served young people in mid-coast Maine since 1994. Its unique long-term mentoring model supports students over six years that begins when they are in 7th grade and continues until they graduate high school. Trekkers’ model focuses on building social, emotional and intellectual resiliency in young people through one-to-one peer mentoring, as well as the use of expeditionary learning, community service and adventure-based education. Trekkers’ programs are designed to provide an ongoing supportive network for young people in the community by connecting them with caring adults while …

Dental Hygiene Students Reported Physiological Symptoms Associated With Wearing An N95 Respirator Mask, Peyton Shea Butler

Dental Hygiene Theses & Dissertations

Purpose: Physiological symptoms and comfort levels while wearing an N95 respiratory mask has not been examined with dental hygienists. The purpose of this study was to investigate dental hygiene students reported physiological symptoms and comfort perception while wearing an N95 respirator mask during patient care appointments. Methods: After IRB approval (IRB #1987754-2), a 16-item questionnaire was distributed through email to a convenience sample of 65 dental hygiene students. Questions assessed respiratory, dermatologic, cardiac, mask mouth and general physiological symptoms, as well as comfort levels. Additionally, participants were asked to respond to demographic questions and one open ended question inquiring about …

The Prevalence Of Burnout In Saudi Arabia Dental Hygienists, Nouf Hamad Aldayel

Dental Hygiene Theses & Dissertations

Purpose: The purpose of this pilot study was to assess the prevalence of burnout in Saudi Arabian dental hygienists and identify risk factors associated with burnout. Methods: A descriptive survey design using the Copenhagen Burnout Inventory (CBI) assessed burnout among a convenience sample of n=123 Saudi dental hygienists. The survey was disseminated electronically to 1,000 Saudi Arabian dental hygienists. The CBI measures three subscales: personal, work-related, and client/patient-related burnout on a five-point Likert-type scale. The survey also included six demographic questions, two Likert-type, one “yes/no,” and one openended question, related to burnout. Descriptive statistics, one-way between subject’s ANOVA, independent samples …

Bayesian Statistical Modeling Of Spatially Resolved Transcriptomics Data, Xi Jiang

Statistical Science Theses and Dissertations

Spatially resolved transcriptomics (SRT) quantifies expression levels at different spatial locations, providing a new and powerful tool to investigate novel biological insights. As experimental technologies enhance both in capacity and efficiency, there arises a growing demand for the development of analytical methodologies.

One question in SRT data analysis is to identify genes whose expressions exhibit spatially correlated patterns, called spatially variable (SV) genes. Most current methods to identify SV genes are built upon the geostatistical model with Gaussian process, which could limit the models' ability to identify complex spatial patterns. In order to overcome this challenge and capture more types …

Geographic Differences In The Magnitude Of Black-White Disparities In Having Obesity, Steven A. Cohen, Monique J. Brown, Furong Xu, Caitlin C. Nash, Mary L. Greaney

Faculty Publications

Background

Obesity disparities in the United States are well documented, but the limited body of research suggests that geographic factors may alter the magnitude of these disparities. A growing body of evidence has identified a “rural mortality penalty” where morbidity and mortality rates are higher in rural than urban areas, even after controlling for other factors. Black-White differences in health and mortality are more pronounced in rural areas than in urban areas.

Objective

Therefore, the purpose of this study was to explore how rural-urban status and region moderate Black-White health disparities in obesity.

Methods

Data were abstracted from the 2012 …

Multi-Representation Variational Autoencoder Via Iterative Latent Attention And Implicit Differentiation, Nhu Thuat Tran, Hady Wirawan Lauw

Research Collection School Of Computing and Information Systems

Variational Autoencoder (VAE) offers a non-linear probabilistic modeling of user's preferences. While it has achieved remarkable performance at collaborative filtering, it typically samples a single vector for representing user's preferences, which may be insufficient to capture the user's diverse interests. Existing solutions extend VAE to model multiple interests of users by resorting a variant of self-attentive method, i.e., employing prototypes to group items into clusters, each capturing one topic of user's interests. Despite showing improvements, the current design could be more effective since prototypes are randomly initialized and shared across users, resulting in uninformative and non-personalized clusters.To fill the gap, …

Lightning Forecast From Chaotic And Incomplete Time Series Using Wavelet De-Noising And Spatiotemporal Kriging, Jared K. Nystrom, Raymond Hill, Andrew J. Geyer, Joseph J. Pignatiello Jr., Eric Chicken

Faculty Publications

Purpose: Present a method to impute missing data from a chaotic time series, in this case lightning prediction data, and then use that completed dataset to create lightning prediction forecasts.

Design/Methodology/Approach: Using the technique of spatiotemporal kriging to estimate data that is autocorrelated but in space and time. Using the estimated data in an imputation methodology completes a dataset used in lighting prediction.

Findings: The techniques provided prove robust to the chaotic nature of the data, and the resulting time series displays evidence of smoothing while also preserving the signal of interest for lightning prediction.

Abstract © Emerald Publishing …

A New Method To Determine The Posterior Distribution Of Coefficient Alpha, John Mart V. Delosreyes

Psychology Theses & Dissertations

There is a focus within the behavioral/social sciences on non-physical, psychological constructs (i.e., constructs). These constructs are indirectly measured using measurement instruments that consist of questions that capture the manifestations of these constructs. The indirect nature of measuring constructs results in a need of ensuring that measurement instruments are reliable. The most popular statistic used to estimate reliability is coefficient alpha as it is easy to compute and has properties that make it desirable to use. Coefficient alpha’s popularity has resulted in a wide breadth of research into its qualities. Notably, research about coefficient alpha’s distribution has led to developments …

All-Cause And Opioid-Related Mortality Compared Between Traumatic Spinal Cord Injury And The Us General Population, Jaden Whitehead, Beatrice Ugiliweneza

The Cardinal Edge

Individuals with spinal cord injury (SCI) are susceptible to the misuse of opioids due to the introduction of these substances for pain management. There are very few studies examining the relationship between unintentional deaths caused by opioid usage following spinal cord injury. The objective of this study was to evaluate the trend of opioid-related mortality of individuals with spinal cord injury (SCI) over the years and compare these findings to the mortality rates due to opioid misuse in the general population. In this study, we used data provided by the National Spinal Cord Injury Model Systems (NSCIMS) for SCI 1999-2016 …

Reu-Deim Classification Of Hispanic Voters In Hispanic Groups Using Name And Zip Code Data In Palm Beach, Florida, Kamila Soto-Ortiz

Beyond: Undergraduate Research Journal

When it comes to registering to vote, Hispanic voters can only register as “Hispanic” in the “Race/Ethnicity” category, causing difficulties when analyzing voting trends amongst the Hispanic community. Upon the recent idea that not all Hispanic Groups vote the same, the goal is to create a model that can possibly identify a voter’s Hispanic Group with the information provided on the public Florida voter file. This is accomplished using name and zip code data for all voters in Palm Beach, Florida. This paper will explore the model implemented, its findings and limitations. Palm Beach, Florida, is met with low confidence …

Sugar-Sweetened Beverages And Artificially Sweetened Beverages Consumption And The Risk Of Nonalcoholic Fatty Liver (Nafld) And Nonalcoholic Steatohepatitis (Nash), Tung Sung Tseng, Wei Ting Lin, Peng Sheng Ting, Chiung Kuei Huang, Po Hung Chen, Gabrielle V. Gonzalez, Hui Yi Lin

School of Public Health Faculty Publications

Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. However, the impact of different types of SSBs, including artificially sweetened beverages (ASBs), is not clear after controlling for total sugar intake and total caloric intake. The aim of this study was to examine the association between the consumption of different SSBs and the risk of NAFLD and NASH in US adults. The representativeness of 3739 US adults aged ≥20 years …

History And Current Status Of Mediterranean Spotted Fever (Msf) In The Crimean Peninsula And Neighboring Regions Along The Black Sea Coast, Muniver T. Gafarova, Marina E. Eremeeva

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Mediterranean spotted fever (MSF) is a tick-borne rickettsiosis caused by Rickettsia conorii subspecies conorii and transmitted to humans by Rhipicephalus sanguineus ticks. The disease was first discovered in Tunisia in 1910 and was subsequently reported from other Mediterranean countries. The first cases of MSF in the former Soviet Union were detected in 1936 on the Crimean Peninsula. This review summarizes the historic information and main features of MSF in that region and contemporary surveillance and control efforts for this rickettsiosis. Current data pertinent to the epidemiology of the disease, circulation of the ticks and distribution of animal hosts are discussed …

Feasibility Study Of Pavement Rutting Evaluation Method Based On Driving Vibration, Zhang Jinxi, Wang Peirong, Cao Dandan, Ceng Jingxiang

Journal of China & Foreign Highway

To explore the intelligent detection and monitoring methods of pavement performance, this paper utilized the self-developed driving data collection app to collect vibration acceleration and other data of the pavement during driving, and carried out the feasibility study of evaluating the pavement rutting by driving vibration. Firstly, the collected vibration acceleration data was processed for noise reduction, and the driving vibration characteristics in different working conditions were analyzed. Secondly, seven time domain indicators with high correlation between vibration acceleration and the rutting were extracted as the initial set of indicators, and the seven indicators were downscaled into two independent principal …

Influence Of Shear Deformation On Manufacturing And Erection Alignment, Wang Jin, Chen Changsong

Journal of China & Foreign Highway

This paper aims to study the effect of shear deformation on the manufacturing and erection alignment of main girders of free cantilever erection steel box girder bridges and better design the state of bridge formation state. To this end, it calculated the shear stress coefficient of uniformity of the steel box girder’s cross-section by adopting the finite element method and conducted comparison with the solid model of the plate and shell units of the steel box girder. The results show that the shear stress coefficient of uniformity calculated by finite element software is accurate and reliable. Additionally, simple modeling indicates …

Study On Temperature Gradient Of Long-Span Single-Box Double-Chamber Box Girder Bridge, Yang Wenbin

Journal of China & Foreign Highway

In view of the complex temperature effect of the single-box double-chamber box girders, this paper aimed to carry out the temperature gradient study of box girder cross-sections by employing a short-tower single-box double-chamber cable-stayed bridge with span arrangement of (120+120) m. 21 temperature sensors were installed at the cross-sections of large-mileage closure sections, with the set collection frequency of one time per hour and a wireless collection module for data collection. Meanwhile, temperature observation was carried out for a period of 171 d to obtain the distribution law of the temperature gradient in cross-sections of the closure sections. The study …