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Articles 181 - 210 of 595
Full-Text Articles in Statistics and Probability
Effects Of Macronutrients Intake And Physical Activity On Childhood Obesity Of Hispanic Children, Prosanta Barai
Effects Of Macronutrients Intake And Physical Activity On Childhood Obesity Of Hispanic Children, Prosanta Barai
Theses and Dissertations
Obesity has become more ubiquitous during the past few decades, and still, its prevalence is increasing. It is in every population in the world and all regions, including rural parts of low and middle-income countries. In the USA, regardless of age, the severity of obesity is no different from the global trend. Although numerous pieces of literature are available, that tried to find answers to some pressing issues like how obesity can be controlled, but there is little to no study focused on younger children, especially the 4-6-year-old Hispanic population. Our study aimed to determine the causal path among literature …
Neural Networks And Stochastic Differential Equations, Stephanie L. Flores
Neural Networks And Stochastic Differential Equations, Stephanie L. Flores
Theses and Dissertations
Influenced by the seminal work, “Physics Informed Neural Networks” by Raissi et al., 2017, there has been a growing interest in solving and parameter estimation of Nonlinear Partial Differential Equations (PDE) with Deep Neural networks in recent years. In fact, this has broadened the pathways and shed light on deep learning of stochastic differential equations (SDE) and stochastic PDE’s (SPDE).In this work, we intend to investigate the current approaches of solving and parameter estimation of the SDE/SPDE with deep neural networks and the possibility of extending them to obtain more accurate/stable solutions with residual systems and/or generative adversarial neural networks. …
Quantile Differences In The Age-Related Decline In Cardiorespiratory Fitness Between Sexes In Adults Without Type 2 Diabetes Mellitus In The United States, Andrew Ortaglia, Melissa Stansbury, Michael David Wirth, Xuemei Sui, Matteo Bottai
Quantile Differences In The Age-Related Decline In Cardiorespiratory Fitness Between Sexes In Adults Without Type 2 Diabetes Mellitus In The United States, Andrew Ortaglia, Melissa Stansbury, Michael David Wirth, Xuemei Sui, Matteo Bottai
Faculty Publications
Objective: To comprehensively assess the extent to which the decline in cardiorespiratory fitness (CRF) with age differs between sexes. Participants and Methods: This study used data from the Aerobics Center Longitudinal Study, conducted between September 1974 and August 2006, consisting primarily of White adults from middle-to-upper socioeconomic strata restricted to adults without type 2 diabetes mellitus (33,742 men and 9,415 women). Quantile regression models were used to estimate the differences in age-associated changes in CRF between the sexes, estimated using a maximal treadmill test. Results: For adults aged up to 45 years, significant differences in slopes relating to age and …
Computer Aided Diagnosis System For Breast Cancer Using Deep Learning., Asma Baccouche
Computer Aided Diagnosis System For Breast Cancer Using Deep Learning., Asma Baccouche
Electronic Theses and Dissertations
The recent rise of big data technology surrounding the electronic systems and developed toolkits gave birth to new promises for Artificial Intelligence (AI). With the continuous use of data-centric systems and machines in our lives, such as social media, surveys, emails, reports, etc., there is no doubt that data has gained the center of attention by scientists and motivated them to provide more decision-making and operational support systems across multiple domains. With the recent breakthroughs in artificial intelligence, the use of machine learning and deep learning models have achieved remarkable advances in computer vision, ecommerce, cybersecurity, and healthcare. Particularly, numerous …
Statistical Methods For Personalized Treatment Selection And Survival Data Analysis Based On Observational Data With High-Dimensional Covariates., Don Ramesh Dinendra Sudaraka Tholkage
Statistical Methods For Personalized Treatment Selection And Survival Data Analysis Based On Observational Data With High-Dimensional Covariates., Don Ramesh Dinendra Sudaraka Tholkage
Electronic Theses and Dissertations
Due to the wide availability of functional data from multiple disciplines, the studies of functional data analysis have become popular in the recent literature. However, the related development in censored survival data has been relatively sparse. In Chapter 2, we consider the problem of analyzing time-to-event data in the presence of functional predictors. We develop a conditional generalized Kaplan Meier (KM) estimator that incorporates functional predictors using kernel weights and rigorously establishes its asymptotic properties. In addition, we propose to select the optimal bandwidth based on a time-dependent Brier score. We then carry out extensive numerical studies to examine the …
Long-Term Trends In Extreme Environmental Events With Changepoint Detection, Mintaek Lee
Long-Term Trends In Extreme Environmental Events With Changepoint Detection, Mintaek Lee
Boise State University Theses and Dissertations
This dissertation examines long-term trends in extreme environmental events with considerations for changepoints and autocorrelation. Due to changes in measurement location, observer, instrument, sampling protocol, local ecosystem, etc., many environmental time series often contain inhomogeneous changes in their distributions. If ignored in the modeling process, these inhomogeneities could produce misleading estimation of the long-term trends in these environmental extremes. Because documentations for these changepoint-inducing events could be incomplete or missing in many cases, those changepoints need to be estimated from the data. Here, we use a genetic algorithm to estimate the number and times of changepoints in the environmental extremes …
Bayesian Adaptive Designs For Proof-Of-Concept Trials And Platform Trials, Yujie Zhao
Bayesian Adaptive Designs For Proof-Of-Concept Trials And Platform Trials, Yujie Zhao
Dissertations and Theses (Open Access)
With the revolutionary achievement in molecular targeted therapies and cancer immunotherapies, the traditional drug development paradigm in phase II trials becomes increasingly inefficient due to its slow progress, high cost, and high failure rate. Fitting one standard strategy to all different trials also harms its reliability in decision-making because it doesn’t fully use all available resources and information in each trial. It’s crucial to develop novel phase II trial designs to accomplish different objectives for different types of trials. This research mainly focuses on Bayesian adaptive designs for phase II trials. Three types of trials are discussed in which traditional …
Survivor Bond Models For Securitizing Longevity Risk, Priscilla Mansah Codjoe
Survivor Bond Models For Securitizing Longevity Risk, Priscilla Mansah Codjoe
Doctoral Dissertations
"Longevity risk is the risk that a reference population’s mortality rates deviate from what is projected from prior life tables. This is due to discoveries in biological sciences, improved public health measures, and nutrition, which have dramatically increased life expectancy. Longevity risk raises life insurers’ liability, increasing product costs and reserves. Securitization through longevity derivatives is a way of dealing with this risk.
To enhance the pricing of life contingent products, we present an additive type mortality model in the style of the Lee-Carter. This model incorporates policyholder covariates. By using counting processes and martingale machinery, we obtain close form …
Semiparametric Estimation With Clustered Right Censored Data Via Multivariate Gaussian Random Fields, Fathima Zahra Sainul Abdeen
Semiparametric Estimation With Clustered Right Censored Data Via Multivariate Gaussian Random Fields, Fathima Zahra Sainul Abdeen
Doctoral Dissertations
Consider a fixed number of clustered areas identified by their geographical coordinate that are monitored for the occurrences of an event such as pandemic, epidemic, migration to name a few. Data collected on units at all areas include time varying covariates and other environmental factors that may affect event occurrences. The event times in every area can be independent. They can also be correlated with correlation between two units induced by an unobservable frailty. In both cases, the collected data is considered pairwise to account for spatial correlation between all pair of areas. The pairwise right censored data is probit-transformed …
Bidirectional Testing For Repairable Systems Reliability: Power Asymmetries, Panel Of Control Charts, And Reliability Graphics, Sung Keun Koo
Bidirectional Testing For Repairable Systems Reliability: Power Asymmetries, Panel Of Control Charts, And Reliability Graphics, Sung Keun Koo
UNLV Theses, Dissertations, Professional Papers, and Capstones
To a practitioner who chooses to be on the safe side, we offer an option between a cocktail of tests and a solo one-size-fits-all test as a needed antidote to power asymmetries. Two bidirectional tests are first established to empower a basic pair of tests as asymmetrical performances. Unsurprisingly, we’ve seen either bidirectional device championing in one alternative setting, but also being turned against the very setting altered with just one of the composed elements. Progressing by filtering out the bad and enhancing the good, we assemble a hybrid from the empowered pair to restore power symmetries that are thought …
Regression Analysis Of Resilience And Covid-19 In Idaho Counties, Ishrat Zaman
Regression Analysis Of Resilience And Covid-19 In Idaho Counties, Ishrat Zaman
Boise State University Theses and Dissertations
Global pandemic Coronavirus Disease 2019 (COVID-19) has serious harmful effects on our day-to-day lives. To overcome challenges such as this, critical preparedness, readiness, and response actions are required. This thesis uses estimates of community resilience available through the CRE Tool, published by the US Census Bureau, and COVID19 cases published by John Hopkins Coronavirus Research Center for Idaho counties. Simple linear regression analysis was performed to identify a correlation between COVID-19 cases and deaths in Idaho counties and measures of their resilience. Understanding this correlation could lead to better estimation and prediction of the effect of disasters in Idaho’s counties. …
Robust Inference In Wireless Sensor Networks, Santosh Paudel
Robust Inference In Wireless Sensor Networks, Santosh Paudel
Boise State University Theses and Dissertations
This dissertation presents a systematic approach to obtain robust statistical inference schemes in unreliable networks. Statistical inference offers mechanisms for deducing the statistical properties of unknown parameters from the data. In Wireless Sensor Networks (WSNs), sensor outputs are transmitted across a wireless communication network to the fusion center (FC) for final decision-making. The sensor data are not always reliable. Some factors may cause anomaly in network operations, such as malfunction, corruption, or compromised due to some unknown source of contamination or adversarial attacks.
Two standard component failure models are adopted in this study to describe the system vulnerability: the probabilistic …
Defining Areas Of Interest Using Voronoi And Modified Voronoi Tesselations To Analyze Eye-Tracking Data, Joanna D. Coltrin
Defining Areas Of Interest Using Voronoi And Modified Voronoi Tesselations To Analyze Eye-Tracking Data, Joanna D. Coltrin
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Eye tracking is a technology used to track where someone is looking. Eye-tracking technology is often used to study what people focus on when looking at a photo of another person. The eye-tracking technology records points on a photo that a person is looking at. When the photo being looked at shows a person, the points can be categorized by body part such as head, right hand, left hand, and torso. This thesis presents the use of partially circular areas to define the body parts of the person in the photo and therefore categorize the points collected by the eye-tracker. …
Contributions To Random Forest Variable Importance With Applications In R, Kelvyn K. Bladen
Contributions To Random Forest Variable Importance With Applications In R, Kelvyn K. Bladen
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
A major focus in statistics is building and improving computational algorithms that can use data to predict a response. Two fundamental camps of research arise from such a goal. The first camp is researching ways to get more accurate predictions. Many sophisticated methods, collectively known as machine learning methods, have been developed for this very purpose. One such method that is widely used across industry and many other areas of investigation is called Random Forests.
The second camp of research is that of improving the interpretability of machine learning methods. This is worthy of attention when analysts desire to optimize …
Geometry- And Accuracy-Preserving Random Forest Proximities With Applications, Jake S. Rhodes
Geometry- And Accuracy-Preserving Random Forest Proximities With Applications, Jake S. Rhodes
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Many machine learning algorithms use calculated distances or similarities between data observations to make predictions, cluster similar data, visualize patterns, or generally explore the data. Most distances or similarity measures do not incorporate known data labels and are thus considered unsupervised. Supervised methods for measuring distance exist which incorporate data labels and thereby exaggerate separation between data points of different classes. This approach tends to distort the natural structure of the data. Instead of following similar approaches, we leverage a popular algorithm used for making data-driven predictions, known as random forests, to naturally incorporate data labels into similarity measures known …
Changes Overtime In Perinatal Management And Outcomes Of Extremely Preterm Infants In One Tertiary Care Romanian Center, Diana Ungureanu, Nansi Boghossian, Laura Mihaela Suciu
Changes Overtime In Perinatal Management And Outcomes Of Extremely Preterm Infants In One Tertiary Care Romanian Center, Diana Ungureanu, Nansi Boghossian, Laura Mihaela Suciu
Faculty Publications
Background and Objectives: Extremely preterm infants were at increased risk of mortality and morbidity. The purpose of this study was to: (1) examine changes over time in perinatal management, mortality, and major neonatal morbidities among infants born at 250–286 weeks’ gestational age and cared for at one Romanian tertiary care unit and (2) compare the differences with available international data. Material and Methods: This study consisted of infants born at 250–286 weeks in one tertiary neonatal academic center in Romania during two 4-year periods (2007–2010 and 2015–2018). Major morbidities were defined as any of …
Random Walks In The Quarter Plane: Solvable Models With An Analytical Approach, Harshita Bali, Enrico Au-Yeung
Random Walks In The Quarter Plane: Solvable Models With An Analytical Approach, Harshita Bali, Enrico Au-Yeung
DePaul Discoveries
Initially, an urn contains 3 blue balls and 1 red ball. A ball is randomly chosen from the urn. The ball is returned to the urn, together with one additional ball of the same type (red or blue). When the urn has twenty balls in it, what is the probability that exactly ten balls are blue? This is a model for a random process. This urn model has been extended in various ways and we consider some of these generalizations. Urn models can be formulated as random walks in the quarter plane. Our findings indicate that for a specific type …
Spotted Fever Group Rickettsioses In Central America: The Research And Public Health Disparity Among Socioeconomic Lines, Kyndall C. Dye-Braumuller, Marvin S. Rodriguez Aquino, Stella C.W. Self, Mufaro Kanyangarara, Melissa Nolan Ph.D., Mph
Spotted Fever Group Rickettsioses In Central America: The Research And Public Health Disparity Among Socioeconomic Lines, Kyndall C. Dye-Braumuller, Marvin S. Rodriguez Aquino, Stella C.W. Self, Mufaro Kanyangarara, Melissa Nolan Ph.D., Mph
Faculty Publications
Tick-borne diseases including rickettsial diseases are increasing in incidence worldwide. Many rickettsial pathogens can cause disease which is commonly underdiagnosed and underreported; Rickettsia pathogens in the spotted fever group (SFGR) are thus classified as neglected bacterial pathogens. The Central American region shoulders a large proportion of the global neglected disease burden; however, little is known regarding SFGR disease here. Although development varies, four of the seven countries in this region have both the highest poverty rates and SFGR disease burdens (El Salvador, Honduras, Guatemala, and Nicaragua), compared to Belize, Panama, and Costa Rica. Utilizing the Human Development Index (HDI), we …
Capturing The Pool Dilution Effect In Group Testing Regression: A Bayesian Approach, Stella Self Ph.D., Ms, Christopher Mcmahan, Stefani Mokalled
Capturing The Pool Dilution Effect In Group Testing Regression: A Bayesian Approach, Stella Self Ph.D., Ms, Christopher Mcmahan, Stefani Mokalled
Faculty Publications
Group (pooled) testing is becoming a popular strategy for screening large populations for infectious diseases. This popularity is owed to the cost savings that can be realized through implementing group testing methods. These methods involve physically combining biomaterial (eg, saliva, blood, urine) collected on individuals into pooled specimens which are tested for an infection of interest. Through testing these pooled specimens, group testing methods reduce the cost of diagnosing all individuals under study by reducing the number of tests performed. Even though group testing offers substantial cost reductions, some practitioners are hesitant to adopt group testing methods due to the …
Joint Models For Repeated Measured, Non-Normally Distributed Multilevel Data, Weiwei He
Joint Models For Repeated Measured, Non-Normally Distributed Multilevel Data, Weiwei He
USF Tampa Graduate Theses and Dissertations
Clinical trials have tended to collect both survival information and longitudinal biomarkers, as well as other covariates. In order to better assess the severity of diverse diseases, we need to collect various longitudinal outcomes. Furthermore, longitudinal data could consist of a number of different measurements of varying types. The multilevel item response theory (MLIRT) model has been widely used in several fields such as public health and health sciences for multivariate longitudinal outcomes. Joint models combining the longitudinal and survival processes, as well as the relation between them, have been developed to minimize bias and improve the efficiency of estimates. …
The Impact Of Service Dogs On Objective And Perceived Sleep Quality For Veterans With Ptsd, Madhuri Vempati, Elise A. Miller, Sarah C. Leighton, Leanne O. Nieforth, Marguerite O’Haire
The Impact Of Service Dogs On Objective And Perceived Sleep Quality For Veterans With Ptsd, Madhuri Vempati, Elise A. Miller, Sarah C. Leighton, Leanne O. Nieforth, Marguerite O’Haire
Discovery Undergraduate Interdisciplinary Research Internship
One in four post-9/11 veterans (Fulton et al., 2015) have been diagnosed with posttraumatic stress disorder (PTSD), facing sleep disruptions as one of their most common symptoms. Service dogs have become an increasingly popular complementary intervention and anecdotes suggest they may impact sleep for veterans with PTSD. There is a need for empirical investigation into these claims through measurement and analysis of sleep quality.
The purpose of this study was to longitudinally investigate the impact of service dogs on sleep quality through both objective and subjective measures.
Participants in the treatment group (n=92) received a service dog after baseline, while …
Concerns With Taking The Covid-19 Vaccine, Kaela Bellamy, Robert S. Keyser
Concerns With Taking The Covid-19 Vaccine, Kaela Bellamy, Robert S. Keyser
The Kennesaw Journal of Undergraduate Research
This IRB-approved descriptive study provides an overview of the concerns associated with receiving a COVID-19 vaccination within the Kennesaw State University community, an R2 university with over 41,000 students, and uses a survey to provide insight into how students, faculty, staff, and administrators are responding to the vaccinations for COVID-19, both available and unavailable, and their preferences. Our research findings indicate that: 1) Most of the population at Kennesaw State University intends to receive the vaccine, regardless of their concerns; 2) The majority of the participants who are either employed or provided an education by Kennesaw State University plan to …
Spatio-Temporal Models Of Infectious Disease With High Rates Of Asymptomatic Transmission, Aminur Rahman, Angela Peace, Ramesh Kesawan, Souparno Ghosh
Spatio-Temporal Models Of Infectious Disease With High Rates Of Asymptomatic Transmission, Aminur Rahman, Angela Peace, Ramesh Kesawan, Souparno Ghosh
Department of Statistics: Faculty Publications
The surprisingly mercurial Covid-19 pandemic has highlighted the need to not only accelerate research on infectious disease, but to also study them using novel techniques and perspectives. A major contributor to the dificulty of containing the current pandemic is due to the highly asymptomatic nature of the disease. In this investigation, we develop a modeling framework to study the spatio-temporal evolution of diseases with high rates of asymptomatic transmission, and we apply this framework to a hypothetical country with mathematically tractable geography; namely, square counties uniformly organized into a rectangle. We first derive a model for the temporal dynamics of …
Respiratory, Neurological And Other Health Outcomes Among Plastic Factory Workers In Gazipur, Bangladesh, Shobhan Das, Md. Masudur Rahman, Asmaul Husna, Margia Akter, Md. Matiur Rahaman, Md. Taohidul Islam, Md. Jamal Uddin, Atin Adhikari
Respiratory, Neurological And Other Health Outcomes Among Plastic Factory Workers In Gazipur, Bangladesh, Shobhan Das, Md. Masudur Rahman, Asmaul Husna, Margia Akter, Md. Matiur Rahaman, Md. Taohidul Islam, Md. Jamal Uddin, Atin Adhikari
Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications
Background: Approximately three thousand plastic goods manufacturing factories (PGMF) are currently operating in Bangladesh involving numerous workers. Associated health problems of these workers are largely unknown. The key objectives of the current study were identifying plastic chemical exposures related health outcomes in these workers and comparing these outcomes before and after their joining in PGMFs. In addition, we aimed to investigate the relationships between work duration and the prevalence of health ailments among workers.
Method: A cross-sectional study was carried out among factory workers (n=405) at six PGMFs in Gazipur district in Bangladesh. A simple random sampling method had been …
Delay Dynamic Equations On Isolated Time Scales And The Relevance Of One-Periodic Coefficients, Martin Bohner, Tom Cuchta, Sabrina Streipert
Delay Dynamic Equations On Isolated Time Scales And The Relevance Of One-Periodic Coefficients, Martin Bohner, Tom Cuchta, Sabrina Streipert
Mathematics and Statistics Faculty Research & Creative Works
We are motivated by the idea that certain properties of delay differential and difference equations with constant coefficients arise as a consequence of their one-periodic nature. We apply the recently introduced definition of periodicity for arbitrary isolated time scales to linear delay dynamic equations and a class of nonlinear delay dynamic equations. Utilizing a derived identity of higher order delta derivatives and delay terms, we rewrite the considered linear and nonlinear delayed dynamic equations with one-periodic coefficients as a linear autonomous dynamic system with constant matrix. As the simplification of a constant matrix is only obtained for one-periodic coefficients, dynamic …
Effect Of Phylogeny Misestimation On Estimating Trait Evolution Parameters, Tabytha Ariel Perez
Effect Of Phylogeny Misestimation On Estimating Trait Evolution Parameters, Tabytha Ariel Perez
Mathematics & Statistics ETDs
Biologists are interested in estimating trait evolution models from phylogenies. However, phylogenies are imperfectly estimated, generally from DNA sequence data. In this study, true phylogenies are simulated to understand whether errors in phylogeny estimation affect inference of the trait evolution model. Given the tree, DNA sequences as well as traits are then simulated from the true phylogeny; both are simulated independently from the other. After the simulation, the DNA sequences were used to estimate trees using the UPGMA method without utilizing the trait information. The estimated trees combined with the traits are used to infer the evolutionary trait models, specifically …
Consequences Of Gulf Of Mexico Estuarine Tropical Cyclone Disturbance Regimes For Fish Assemblage Dynamics Conditionally Depend On Life-History Traits And Niche Characteristics, Stephen Edward Potts
Consequences Of Gulf Of Mexico Estuarine Tropical Cyclone Disturbance Regimes For Fish Assemblage Dynamics Conditionally Depend On Life-History Traits And Niche Characteristics, Stephen Edward Potts
LSU Doctoral Dissertations
Tropical cyclones (TC) are intense, localized disturbances that can potentially cause extensive damage to ecosystems. This dissertation is motivated by a need for interdisciplinary study of TC-ecosystem dynamics with applications to ecology, geography, and analytical methodology. I explore concept linkages between TC dynamics and ecosystems to characterize TC-ecosystem relationships as ecological disturbance regimes. This dissertation tests hypotheses and relationships of TC effects on estuarine fish assemblages in the north-western Gulf of Mexico. I explore concepts in TC-ecosystem relationships to link biotic dynamics with physical disturbance.
In Chapter 2, I compared spatial performance of generalized linear models (GLMs) and generalized additive …
Impact Of Oil And A Tropical Cyclone On An Omnivore And Herbivore Population In Salt Marshes Of Louisiana, Hannah K. Gordon
Impact Of Oil And A Tropical Cyclone On An Omnivore And Herbivore Population In Salt Marshes Of Louisiana, Hannah K. Gordon
LSU Master's Theses
Terrestrial arthropods are the ideal ecological indicators for the health of a salt marsh. Salt marshes are under extreme continuous stressors including climate change, land loss, oil spills, and tropical cyclones. Such stressors impact trophic and species level interactions, food resources, dispersal and population size of insects. In the present study, we collected terrestrial arthropods from eleven sites around Barataria Bay, five sites were oiled and five sites were unoiled, to determine the impact of the redistribution of oil from the Deepwater Horizon oil spill. Site C6 was excluded from the oiled and unoiled data because it was in close …
Talking About Statistical Significance In Numeracy, Nathan D. Grawe, Gizem Karaali
Talking About Statistical Significance In Numeracy, Nathan D. Grawe, Gizem Karaali
Numeracy
In recent years, much debate has surrounded the potential for audiences to be mislead by several common practices when reporting statistical significance tests. Two editors of Numeracy share the journals perspectives on these questions. As an interdisciplinary journal, we recognize and honor the genre differences represented by our authors and audience members. As a consequence, the journal is open to many practices. Still, we acknowledge the concerns raised by the American Statistical Association and others and encourage authors to write with care and clarity, however results may be represented.
Heterogeneity Of Gene Trees, Jonathan Nenye Odumegwu Unm
Heterogeneity Of Gene Trees, Jonathan Nenye Odumegwu Unm
Mathematics & Statistics ETDs
Multilocus phylogenetic studies often show a high degree of gene tree heterogeneity —gene trees that have different topologies from each other as well as from the species tree topology. In some cases, this can lead to studies with hundreds of loci having distinct gene tree topologies. The degree of heterogeneity is expected to increase when there is a high degree of incomplete lineage sorting due to short branches (as measured in coalescent units) in the species tree. Other potential sources of heterogeneity include other biological processes such as introgression, recombination within genes, ancestral population structure, gene duplication and loss, and …