Statistics and Probability Commons^™

Meta-Analysis Of Social-Personality Psychological Research, Blair T. Johnson, Alice H. Eagly

CHIP Documents

This publication provides a contemporary treatment of the subject of meta-analysis in relation to social-personality psychology. Meta-analysis literally refers to the statistical pooling of the results of independent studies on a given subject, although in practice it refers as well to other steps of research synthesis, including defining the question under investigation, gathering all available research reports, coding of information about the studies and their effects, and interpretation/dissemination of results. Discussed as well are the hallmarks of high-quality meta-analyses.

Changing Minds To Changing The World: Mapping The Spectrum Of Intent In Data Visualization And Data Arts, Scott Murray

Art + Architecture

No abstract provided.

A Linear Iteration Algorithm For A Second-Order Energy Stable Scheme For A Thin Film Model Without Slope Selection, Wenbin Chen, Cheng Wang, Xiaoming Wang, Steven M. Wise

Mathematics and Statistics Faculty Research & Creative Works

We present a linear iteration algorithm to implement a second-order energy stable numerical scheme for a model of epitaxial thin film growth without slope selection. the PDE, which is a nonlinear, fourth-order parabolic equation, is the L 2 gradient flow of the energy d x. the energy stability is preserved by a careful choice of the second-order temporal approximation for the nonlinear term, as reported in recent work (Shen et al. in SIAM J Numer Anal 50:105-125, 2012). the resulting scheme is highly nonlinear, and its implementation is non-trivial. in this paper, we propose a linear iteration algorithm to solve …

Linking Instrumental Neutron Activation Analysis (Inaa) With Geology In The Ancestral Caddo Region, Robert Z. Selden Jr.

CRHR: Archaeology

This poster illustrates the success of a novel method of INAA that was employed to reveal geochemical signatures in Caddo ceramic vessel sherds that correlate with local surficial geology. The geochemical data from the sherd assemblage were used within an exploration of potential ceramic provenance, which was successful at demarcating sherds from ceramic vessels made from clays in either the Claiborne or Wilcox Groups. Further geochemical segregation was also apparent between the Recklaw Formation in the Claiborne Group, and the Weches Formation in the Wilcox Group. These results point to a high degree of geochemical variability within the East Texas …

Instrumental Neutron Activation Analysis (Inaa) Of Shell-Tempered Ceramics In The Ancestral Caddo Region: Rethinking Methods, Robert Z. Selden Jr., Timothy K. Perttula

CRHR: Archaeology

The geochemical analysis of shell-tempered ceramics in the ancestral Caddo region has been a matter of confusion since the mid-1990s. While Caddo archaeologists have long perceived most or all of the shell-tempered ceramics in East Texas to have originated from two different areas within the Red River basin, the geochemical data and interpretations remain inconsistent with that idea. This poster takes another look at this dataset, and considers an approach that was initially put forth by MURR, and then seemingly abandoned. Using only the geochemical data from shell-tempered sherds, we take a closer look at the contributions of calcium (Ca), …

Toward A Morphometric Phylogeny Of Caddo Ceramics: A Test Of 3d Geometric Morphometrics, Robert Z. Selden Jr., Timothy K. Perttula, Michael J. O'Brien

CRHR: Archaeology

In this poster we use 3D geometric morphometrics as an exploratory tool for examining diversity in vessel form (or shape) among 27 whole or reconstructed Caddo vessels from the Vanderpool site in Smith County, Texas. Forty-one landmarks from each vessel were exported to version 2.5 of Morphologika for generalized Procrustes analysis and principal components analysis and were then exported to R for cluster analysis (depending on sample size). Despite the small sample size, results indicate that 3D geometric morphometric analysis is an avenue of ceramic research where substantive analytical gains can be realized.

Advances In Documentation, Digital Curation, Virtual Exhibition, And A Test Of 3d Geometric Morhpometrics: A Case Study Of The Vanderpool Vessels From The Ancestral Caddo Territory, Robert Z. Selden Jr., Timothy K. Perttula, Michael J. O'Brien

CRHR: Archaeology

Three-dimensional (3D) digital scanning of archaeological materials is typically used as a tool for artifact documentation. With the permission of the Caddo Nation of Oklahoma, 3D documentation of Caddo funerary vessels from the Vanderpool site (41SM77) was conducted with the initial goal of ensuring that these data would be publicly available for future research long after the vessels were repatriated. A digital infrastructure was created to archive and disseminate the resultant 3D datasets, ensuring that they would be accessible by both researchers and the general public (CRHR 2014a). However, 3D imagery can be used for much more than documentation. To …

Extending Mendelian Risk Prediction Models To Handle Misreported Family History, Danielle Braun, Malka Gorfine, Hormuzd A. Katki, Argyrios Ziogas, Hoda Anton-Culver, Giovanni Parmigiani

Harvard University Biostatistics Working Paper Series

Mendelian risk prediction models calculate the probability of a proband being a mutation carrier based on family history and known mutation prevalence and penetrance. Family history in this setting, is self-reported and is often reported with error. Various studies in the literature have evaluated misreporting of family history. Using a validation data set which includes both error-prone self-reported family history and error-free validated family history, we propose a method to adjust for misreporting of family history. We estimate the measurement error process in a validation data set (from University of California at Irvine (UCI)) using nonparametric smoothed Kaplan-Meier estimators, and …

Nonparametric Adjustment For Measurement Error In Time To Event Data, Danielle Braun, Malka Gorfine, Hormuzd A. Katki, Argyrios Ziogas, Giovanni Parmigiani

Harvard University Biostatistics Working Paper Series

Measurement error in time to event data used as a predictor will lead to inaccurate predictions. This arises in the context of self-reported family history, a time to event predictor often measured with error, used in Mendelian risk prediction models. Using a validation data set, we propose a method to adjust for this type of measurement error. We estimate the measurement error process using a nonparametric smoothed Kaplan-Meier estimator, and use Monte Carlo integration to implement the adjustment. We apply our method to simulated data in the context of both Mendelian risk prediction models and multivariate survival prediction models, as …

A New Method For Ranking Quarterback Fantasy Performance With Assessment Using Distances Between Rankings, Evan Boyd

Theses, Dissertations and Capstones

Each year around the first week of September, NFL fans are fulfilled with the familiar emotions of watching their team compete for the ultimate prize: Fantasy League Championship. No, the NFL did not rename the Super Bowl. To some, this prize is even more personal than if your favorite childhood NFL team were to win the big game in February. To put it simply, the popularity of fantasy football has grown tremendously over time and the opportunity to best your friends, family, coworkers, whomever it may be that attempts to create the greatest fantasy football roster of all time, absolutely …

Oscillation Criteria For Second-Order Dynamic Equations On Time Scales, Ravi P. Agarwal, Martin Bohner, Tongxing Li, Chenghui Zhang

Mathematics and Statistics Faculty Research & Creative Works

Erbe's and Hassan's contributions regarding oscillation criteria are interesting in the development of oscillation theory of dynamic equations on time scales. The objective of this paper is to amend these results. © 2014 Elsevier Ltd. All rights reserved.

Oscillation Of Second-Order P-Laplace Dynamic Equations With A Nonpositive Neutral Coefficient, Martin Bohner, Tongxing Li

Mathematics and Statistics Faculty Research & Creative Works

We establish some new oscillation criteria for a class of second-order p-Laplace dynamic equations with a nonpositive neutral coefficient on a time scale. The results obtained supplement and improved those reported in the literature. © 2014 Elsevier Ltd. All rights reserved.

Multi-Valued Parabolic Variational Inequalities And Related Variational-Hemivariational Inequalities, Siegfried Carl, Vy Khoi Le

Mathematics and Statistics Faculty Research & Creative Works

In this paper we study multi-valued parabolic variational inequalities involving quasilinear parabolic operators, and multi-valued integral terms over the underlying parabolic cylinder as well as over parts of the lateral parabolic boundary, where the multi-valued functions involved are assumed to be upper semicontinuous only. Note, since lower semicontinuous multi-valued functions allow always for a Carathéodory selection, this case can be considered as the trivial case and therefore will be omitted. Our main goal is threefold: First, we provide an analytical framework and an existence theory for the problems under consideration. Unlike in recent publications on multi-valued parabolic variational inequalities, the …

Asymptotic Behavior Of Nonoscillatory Solutions Of Higher-Order Integro-Dynamic Equations, Martin Bohner, Said Grace, Nasrin Sultana

Mathematics and Statistics Faculty Research & Creative Works

In this paper, we establish some new criteria on the asymptotic behavior of Non oscillatory solutions of higher-order integro-dynamic equations on time scales. © AGH University of Science and Technology Press, Krakow 2014.

Nudging The Fda, W. Nicholson Price Ii, I. Glenn Cohen

Law Faculty Scholarship

[Excerpt] "The FDA’s regulation of drugs is frequently the subject of policy debate, with arguments falling into two camps. On the one hand, a libertarian view of patients and the health care system holds high the value of consumer choice. Patients should get all the information and the drugs they want; the FDA should do what it can to enforce some basic standards but should otherwise get out of the way. On the other hand, a paternalist view values the FDA’s role as an expert agency standing between patients and a set of potentially dangerous drugs and potentially unscrupulous or …

Estimating Population Treatment Effects From A Survey Sub-Sample, Kara E. Rudolph, Ivan Diaz, Michael Rosenblum, Elizabeth A. Stuart

Johns Hopkins University, Dept. of Biostatistics Working Papers

We consider the problem of estimating an average treatment effect for a target population from a survey sub-sample. Our motivating example is generalizing a treatment effect estimated in a sub-sample of the National Comorbidity Survey Replication Adolescent Supplement to the population of U.S. adolescents. To address this problem, we evaluate easy-to-implement methods that account for both non-random treatment assignment and a non-random two-stage selection mechanism. We compare the performance of a Horvitz-Thompson estimator using inverse probability weighting (IPW) and two double robust estimators in a variety of scenarios. We demonstrate that the two double robust estimators generally outperform IPW in …

Confidence Intervals For Ranks Of Age-Adjusted Rates Across States Or Counties, Shunpu Zhang, Jun Luo, Li Zhu, David G. Stinchcomb, Dave Campbell, Ginger Carter, Scott Gilkeson, Eric J. Feuer

Department of Statistics: Faculty Publications

Health indices provide information to the general public on the health condition of the community. They can also be used to inform the government’s policy making, to evaluate the effect of a current policy or healthcare program, or for program planning and priority setting. It is a common practice that the health indices across different geographic units are ranked and the ranks are reported as fixed values. We argue that the ranks should be viewed as random and hence should be accompanied by an indication of precision (i.e., the confidence intervals). A technical difficulty in doing so is how to …

Parametric And Nonparametric Statistical Methods For Genomic Selection Of Traits With Additive And Epistatic Genetic Architectures, Reka Howard, Alicia L. Carriquiry, William D. Beavis

Department of Statistics: Faculty Publications

Parametric and nonparametric methods have been developed for purposes of predicting phenotypes. These methods are based on retrospective analyses of empirical data consisting of genotypic and phenotypic scores. Recent reports have indicated that parametric methods are unable to predict phenotypes of traits with known epistatic genetic architectures. Herein, we review parametric methods including least squares regression, ridge regression, Bayesian ridge regression, least absolute shrinkage and selection operator (LASSO), Bayesian LASSO, best linear unbiased prediction (BLUP), Bayes A, Bayes B, Bayes C, and Bayes Cπ. We also review nonparametric methods including Nadaraya-Watson estimator, reproducing kernel Hilbert space, support vector machine regression, …

Flint International Statistics Conference Announcement, Kettering University

Flint: One City, 100 Years of Variability

CONFERENCE ANNOUNCEMENT POSTER:

Kettering University is organizing this international conference to celebrate the IYS 2013 and the 175th anniversary of the American Statistical Association.

The main focus of this conference will be on STATISTICAL METHODS & STUDIES OF HISTORICAL DATA.

Participants may use any data. Data on Flint—consisting of up to 100 years of demographic, health, labor, census and crime records will be summarized and made available to participants. Sessions will include presentations of the statistical achievements and perspectives, followed by several talks on current results.

The Usefulness Of Systematic Reviews Of Animal Experiments For The Design Of Preclinical And Clinical Studies, Rob B.M. De Vries, Kimberley E. Weaver, Marc T. Avey, Martin Stephens, Emily S. Sena, Marlies Leenaars

Experimentation Collection

The question of how animal studies should be designed, conducted, and analyzed remains underexposed in societal debates on animal experimentation. This is not only a scientific but also amoral question. After all, if animal experiments are not appropriately designed, conducted, and analyzed, the results produced are unlikely to be reliable and the animals have in effect been wasted. In this article, we focus on one particular method to address this moral question, namely systematic reviews of previously performed animal experiments. We discuss how the design, conduct, and analysis of future (animal and human) experiments may be optimized through such systematic …

Lost In Translation: Animal Models And Clinical Trials In Cancer Treatment, Isabella W.Y. Mak, Nathan Evaniew, Michelle Ghert

Human Clinical Trials Collection

Due to practical and ethical concerns associated with human experimentation, animal models have been essential in cancer research. However, the average rate of successful translation from animal models to clinical cancer trials is less than 8%. Animal models are limited in their ability to mimic the extremely complex process of human carcinogenesis, physiology and progression. Therefore the safety and efficacy identified in animal studies is generally not translated to human trials. Animal models can serve as an important source of in vivo information, but alternative translational approaches have emerged that may eventually replace the link between in vitro studies and …

Some Dynamic Hardy-Type Inequalities With General Kernel, Martin Bohner, Ammara Nosheen, Josip Pečarić, Awais Younus

Mathematics and Statistics Faculty Research & Creative Works

In this paper, we extend some Hardy-type inequalities with certain kernels to arbitrary time scales. Certain classical and some new integral and discrete inequalities are deduced in seek of applications. © Zagreb Paper JMI-08-12.

Set-Based Tests For Genetic Association In Longitudinal Studies, Zihuai He, Min Zhang, Seunggeun Lee, Jennifer A. Smith, Xiuqing Guo, Walter Palmas, Sharon L.R. Kardia, Ana V. Diez Roux, Bhramar Mukherjee

The University of Michigan Department of Biostatistics Working Paper Series

Genetic association studies with longitudinal markers of chronic diseases (e.g., blood pressure, body mass index) provide a valuable opportunity to explore how genetic variants affect traits over time by utilizing the full trajectory of longitudinal outcomes. Since these traits are likely influenced by the joint effect of multiple variants in a gene, a joint analysis of these variants considering linkage disequilibrium (LD) may help to explain additional phenotypic variation. In this article, we propose a longitudinal genetic random field model (LGRF), to test the association between a phenotype measured repeatedly during the course of an observational study and a set …

R Code To Accompany “Principal Component Analysis And Optimization: A Tutorial”, Robert Reris, J. Paul Brooks

Statistical Sciences and Operations Research Data

This data accompanies "Principal Component Analysis and Optimization: A Tutorial" by Robert Reris and J. Paul Brooks, presented at the 2015 INFORMS Computing Society Conference, Operations Research and Computing: Algorithms and Software for Analytics, Richmond, Virginia January 11-13, 2015.

The data contains R code, output, and comments that follow the examples for principal component analysis in the paper.

Data Files To Accompany "The Support Vector Machine And Mixed Integer Linear Programming: Ramp Loss Svm With L1-Norm Regularization", Eric J. Hess, J. Paul Brooks

Statistical Sciences and Operations Research Data

These files accompany, "The Support Vector Machine and Mixed Integer Linear Programming: Ramp Loss SVM with L1-Norm Regularization" by Eric J. Hess and J. Paul Brooks, presented at the 2015 INFORMS Computing Society Conference, Operations Research and Computing: Algorithms and Software for Analytics, Richmond, Virginia January 11-13, 2015.

The files contain instances of optimization problems that are described in the paper and for which results are reported. The files are in CPLEX LP format. The naming convention of the files is as follows: ndBTj0F.lp, where is the number of samples, is the number of attributes, and refers to …

Cycle Lengths Of Θ-Biased Random Permutations, Tongjia Shi

HMC Senior Theses

Consider a probability distribution on the permutations of n elements. If the probability of each permutation is proportional to θ^K, where K is the number of cycles in the permutation, then we say that the distribution generates a θ-biased random permutation. A random permutation is a special θ-biased random permutation with θ = 1. The m^th moment of the r^th longest cycle of a random permutation is Θ(n^m), regardless of r and θ. The joint moments are derived, and it is shown that the longest cycles of a permutation can either be positively or …

Vulnerability Analysis Of Cyber-Behavioral Biometric Authentication, Abdul Serwadda

Doctoral Dissertations

Research on cyber-behavioral biometric authentication has traditionally assumed naïve (or zero-effort) impostors who make no attempt to generate sophisticated forgeries of biometric samples. Given the plethora of adversarial technologies on the Internet, it is questionable as to whether the zero-effort threat model provides a realistic estimate of how these authentication systems would perform in the wake of adversity. To better evaluate the efficiency of these authentication systems, there is need for research on algorithmic attacks which simulate the state-of-the-art threats.

To tackle this problem, we took the case of keystroke and touch-based authentication and developed a new family of algorithmic …

Analysis Of Schizophrenia Data Using A Nonlinear Threshold Index Logistic Model., Zhenyu Jiang, Chengan Du, Assen Jablensky, Hua Liang, Zudi Lu, Yang Ma, Kok Lay Teo

GW Biostatistics Center

Genetic information, such as single nucleotide polymorphism (SNP) data, has been widely recognized as useful in prediction of disease risk. However, how to model the genetic data that is often categorical in disease class prediction is complex and challenging. In this paper, we propose a novel class of nonlinear threshold index logistic models to deal with the complex, nonlinear effects of categorical/discrete SNP covariates for Schizophrenia class prediction. A maximum likelihood methodology is suggested to estimate the unknown parameters in the models. Simulation studies demonstrate that the proposed methodology works viably well for moderate-size samples. The suggested approach is therefore …

Mediation Analysis Of Gestational Age, Congenital Heart Defects, And Infant Birth-Weight, Adane Wogu, Christopher Loffredo, Ionut Bebu, George Luta

GW Biostatistics Center

Background

In this study we assessed the mediation role of the gestational age on the effect of the infant’s congenital heart defects (CHD) on birth-weight.

Methods

We used secondary data from the Baltimore-Washington Infant Study (1981–1989). Mediation analysis was employed to investigate whether gestational age acted as a mediator of the association between CHD and reduced birth-weight. We estimated the mediated effect, the mediation proportion, and their corresponding 95% confidence intervals (CI) using several methods.

Results

There were 3362 CHD cases and 3564 controls in the dataset with mean birth-weight of 3071 (SD = 729) and 3353 (SD = 603) …

Engagement With Care, Substance Use, And Adherence To Therapy In Hiv/Aids, Patrice K. Nicholas, Suzanne Willard, Clinton J. Thompson, Carol Dawson-Rose, Inge B. Corless, +20 Additional Authors

GW Biostatistics Center

Engagement with care for those living with HIV is aimed at establishing a strong relationship between patients and their health care provider and is often associated with greater adherence to therapy and treatment (Flickinger, Saha, Moore, and Beach, 2013). Substance use behaviors are linked with lower rates of engagement with care and medication adherence (Horvath, Carrico, Simoni, Boyer, Amico, and Petroli, 2013). This study is a secondary data analysis using a cross-sectional design from a larger randomized controlled trial (n = 775) that investigated the efficacy of a self-care symptom management manual for participants living with HIV. Participants were …