Statistics and Probability Commons^™

Cancer Modeling: From Optimal Cell Renewal To Immunotherapy, Cesar L. Alvarado

Mathematics & Statistics ETDs

Cancer is a disease caused by mutations in normal cells. According to the National Cancer Institute, in 2016, an estimated 1.6 million people were diagnosed and approximately 0.5 million people died from the disease in the United States. There are many factors that shape cancer at the cellular and organismal level, including genetic, immunological, and environmental components. In this thesis, we show how mathematical modeling can be used to provide insight into some of the key mechanisms underlying cancer dynamics. First, we use mathematical modeling to investigate optimal homeostatic cell renewal in tissues such as the small intestine with an …

Modeling Trait Evolutionary Processes With More Than One Gene, Huan Jiang

Mathematics & Statistics ETDs

Phylogenetic comparative methods have been used to test evolutionary signals through trait evolutionary processes. Traditionally, biologists use one phylogenetic tree as a tool to handle dependent data for the traits of interest and hence utilize one gene only. However, it is more informative if the evolutionary processes of a trait are presented by phylogenetic trees reconstructed by the DNA alignments from more than one gene. In this work, we explain and develop two methods involving modeling the trait evolutionary processes: (a) two gene trees via the Brownian motion (BM) model; and (b) two gene trees via the Ornstein-Uhlenbeck (OU) model. …

Contributions To Statistical Testing, Prediction, And Modeling, John C. Pesko

Mathematics & Statistics ETDs

1. "Parametric Bootstrap (PB) and Objective Bayesian (OB) Testing with Applications to Heteroscedastic ANOVA": For one-way heteroscedastic ANOVA, we show a close relationship between the PB and OB approaches to significance testing, demonstrating the conditions for which the two approaches are equivalent. Using a simulation study, PB and OB performance is compared to a test based on the predictive distribution as well as the unweighted test of Akritas & Papadatos (2004). We extend this work to the RCBD with subsampling model, and prove a repeated sampling property and large sample property for general OB significance testing.

2. "Early Identification of …

The Use Of The Pivot Pairwise Relative Criteria Importance Assessment Method For Determining The Weights Of Criteria, Florentin Smarandache, Dragisa Stanujkic, Edmundas Kazimieras Zavadskas, Darjan Karabasevic, Zenonas Turskis

Branch Mathematics and Statistics Faculty and Staff Publications

The weights of evaluation criteria could have a significant impact on the results obtained by applying multiple criteria decision-making methods. Therefore, the two extensions of the SWARA method that can be used in cases when it is not easy, or even is impossible to reach a consensus on the expected importance of the evaluation criteria are proposed in this paper. The primary objective of the proposed extensions is to provide an understandable and easy-to-use approach to the collecting of respondents’ real attitudes towards the significance of evaluation criteria and to also provide an approach to the checking of the reliability …

What Affects Parents’ Choice Of Milk? An Application Of Bayesian Model Averaging, Yingzhe Cheng

Mathematics & Statistics ETDs

This study identifies the factors that influence parents’ choice of milk for their children, using data from a unique survey administered in 2013 in Hunan province, China. In this survey, we identified two brands of milk, which differ in their prices and safety claims by the producer. Data were collected on parents’ choice of milk between the two brands, demographics, attitude towards food safety and behaviors related to food. Stepwise model selection and Bayesian model averaging (BMA) are used to search for influential factors. The two approaches consistently select the same factors suggested by an economic theoretical model, including price …

Mechanistic Plug-And-Play Models For Understanding The Impact Of Control And Climate On Seasonal Dengue Dynamics In Iquitos, Peru, Nathan Levick

Mathematics & Statistics ETDs

Dengue virus is a mosquito-borne multi-serotype disease whose dynamics are not precisely understood despite half of the world’s human population being at risk of infection. A recent dataset of dengue case reports from an isolated Amazonian city— Iquitos, Peru—provides a unique opportunity to assess dengue dynamics in a simpli- fied setting. Ten years of clinical surveillance data reveal a specific pattern: two novel serotypes, in turn, invaded and exclusively dominated incidence over several seasonal cycles, despite limited intra-annual variation in climate conditions. Together with mechanistic mathematical models, these data can provide an improved understand- ing of the nonlinear interactions between …

Searching Neuroimaging Biomarkers In Mental Disorders With Graph And Multimodal Fusion Analysis Of Functional Connectivity, Hao He

Electrical and Computer Engineering ETDs

Mental disorders such as schizophrenia (SZ), bipolar (BD), and major depression disorders (MDD) can cause severe symptoms and life disruption. They share some symptoms, which can pose a major clinical challenge to their differentiation. Objective biomarkers based on neuroimaging may help to improve diagnostic accuracy and facilitate optimal treatment for patients. Over the last decades, non-invasive in-vivo neuroimaging techniques such as magnetic resonance imaging (MRI) have been increasingly applied to measure structure and function in human brains. With functional MRI (fMRI) or structural MRI (sMRI), studies have identified neurophysiological deficits in patients’ brain from different perspective. Functional connectivity (FC) analysis …

Towards Deeper Understanding In Neuroimaging, Rex Devon Hjelm

Computer Science ETDs

Neuroimaging is a growing domain of research, with advances in machine learning having tremendous potential to expand understanding in neuroscience and improve public health. Deep neural networks have recently and rapidly achieved historic success in numerous domains, and as a consequence have completely redefined the landscape of automated learners, giving promise of significant advances in numerous domains of research. Despite recent advances and advantages over traditional machine learning methods, deep neural networks have yet to have permeated significantly into neuroscience studies, particularly as a tool for discovery. This dissertation presents well-established and novel tools for unsupervised learning which aid in …

Advanced Data Analysis - Lecture Notes, Erik B. Erhardt, Edward J. Bedrick, Ronald M. Schrader

Open Textbooks

Lecture notes for Advanced Data Analysis (ADA1 Stat 427/527 and ADA2 Stat 428/528), Department of Mathematics and Statistics, University of New Mexico, Fall 2016-Spring 2017. Additional material including RMarkdown templates for in-class and homework exercises, datasets, R code, and video lectures are available on the course websites: https://statacumen.com/teaching/ada1 and https://statacumen.com/teaching/ada2 .

Contents

I ADA1: Software

• 0 Introduction to R, Rstudio, and ggplot

II ADA1: Summaries and displays, and one-, two-, and many-way tests of means

• 1 Summarizing and Displaying Data
• 2 Estimation in One-Sample Problems
• 3 Two-Sample Inferences
• 4 Checking Assumptions
• 5 One-Way Analysis of Variance

III ADA1: Nonparametric, categorical, …

Data Driven Sample Generator Model With Application To Classification, Alvaro Emilio Ulloa Cerna

Mathematics & Statistics ETDs

Despite the rapidly growing interest, progress in the study of relations between physiological abnormalities and mental disorders is hampered by complexity of the human brain and high costs of data collection. The complexity can be captured by machine learning approaches, but they still may require significant amounts of data. In this thesis, we seek to mitigate the latter challenge by developing a data driven sample generator model for the generation of synthetic realistic training data. Our method greatly improves generalization in classification of schizophrenia patients and healthy controls from their structural magnetic resonance images. A feed forward neural network trained …

Neutrosophic Overset, Neutrosophic Underset, And Neutrosophic Offset. Similarly For Neutrosophic Over-/Under-/Off- Logic, Probability, And Statistics, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Neutrosophic Over-/Under-/Off-Set and -Logic were defined for the first time by Smarandache in 1995 and published in 2007. They are totally different from other sets/logics/probabilities.

He extended the neutrosophic set respectively to Neutrosophic Overset {when some neutrosophic component is > 1}, Neutrosophic Underset {when some neutrosophic component is < 0}, and to Neutrosophic Offset {when some neutrosophic components are off the interval [0, 1], i.e. some neutrosophic component > 1 and other neutrosophic component < 0}.

This is no surprise with respect to the classical fuzzy set/logic, intuitionistic fuzzy set/logic, or classical/imprecise probability, where the values are not allowed outside the interval [0, 1], since our real-world has …

Pcr5 And Neutrosophic Probability In Target Identification, Florentin Smarandache, Nassim Abbas, Youcef Chibani, Bilal Hadjadji, Zayen Azzouz Omar

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper we use PCR5 in order to fusion the information of two sources providing subjective probabilities of an event A to occur in the following form: chance that A occurs, indeterminate chance of occurrence of A, chance that A does not occur.

Per-Contact Infectivity Of Hcv Associated With Injection Exposures In A Prospective Cohort Of Young Injection Drug Users In San Francisco, Ca (Ufo Study), Yuridia Leyva

Mathematics & Statistics ETDs

Sharing needles and ancillary injection drug equipment places injection drug users (IDU) at risk for Hepatitis C Virus (HCV), a highly infectious blood-borne virus. A limited number of studies have analyzed the per-contact infectivity of HCV associated with the use of previously-used needles, but per-contact infectivity of ancillary injecting equipment has not been previously investigated. Our goal is to estimate the per-contact infectivity of HCV associated with (1) injecting with another person's previously-used needle, classified as receptive needle sharing (RNS), and (2) using another person's previously-used ancillary injecting equipment, such as cookers to melt drugs and cottons to strain impurities …

Introduction To Neutrosophic Statistics, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Neutrosophic Statistics means statistical analysis of population or sample that has indeterminate (imprecise, ambiguous, vague, incomplete, unknown) data. For example, the population or sample size might not be exactly determinate because of some individuals that partially belong to the population or sample, and partially they do not belong, or individuals whose appurtenance is completely unknown. Also, there are population or sample individuals whose data could be indeterminate.

In this book, we develop the 1995 notion of neutrosophic statistics. We present various practical examples. It is possible to define the neutrosophic statistics in many ways, because there are various types of …

The Efficient Use Of Supplementary Information In Finite Population Sampling, Florentin Smarandache, Rajesh Singh

Branch Mathematics and Statistics Faculty and Staff Publications

The purpose of writing this book is to suggest some improved estimators using auxiliary information in sampling schemes like simple random sampling, systematic sampling and stratified random sampling. This volume is a collection of five papers, written by nine co-authors (listed in the order of the papers): Rajesh Singh, Mukesh Kumar, Manoj Kr. Chaudhary, Cem Kadilar, Prayas Sharma, Florentin Smarandache, Anil Prajapati, Hemant Verma, and Viplav Kr. Singh. In first paper dual to ratio-cum-product estimator is suggested and its properties are studied. In second paper an exponential ratio-product type estimator in stratified random sampling is proposed and its properties are …

Fusion Of Masses Defined On Infinite Countable Frames Of Discernment, Florentin Smarandache, Arnaud Martin

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper we introduce for the first time the fusion of information on infinite discrete frames of discernment and we give general results of the fusion of two such masses using the Dempster’s rule and the PCR5 rule for Bayesian and non-Bayesian cases.

A General Procedure Of Estimating Population Mean Using Information On Auxiliary Attribute, Sachin Malik, Rajesh Singh, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This paper deals with the problem of estimating the finite population mean when some information on auxiliary attribute is available. It is shown that the proposed estimator is more efficient than the usual mean estimator and other existing estimators. The results have been illustrated numerically by taking empirical population considered in the literature.

A Generalized Family Of Estimators For Estimating Population Mean Using Two Auxiliary Attributes, Sachin Malik, Rajesh Singh, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This paper deals with the problem of estimating the finite population mean when some information on two auxiliary attributes are available. A class of estimators is defined which includes the estimators recently proposed by Malik and Singh (2012), Naik and Gupta (1996) and Singh et al. (2007) as particular cases. It is shown that the proposed estimator is more efficient than the usual mean estimator and other existing estimators. The study is also extended to two-phase sampling. The results have been illustrated numerically by taking empirical population considered in the literature.

N-Valued Refined Neutrosophic Logic And Its Applications To Physics, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper we present a short history of logics: from particular cases of 2-symbol or numerical valued logic to the general case of n-symbol or numerical valued logic. We show generalizations of 2-valued Boolean logic to fuzzy logic, also from the Kleene’s and Lukasiewicz’ 3-symbol valued logics or Belnap’s 4-symbol valued logic to the most general n-symbol or numerical valued refined neutrosophic logic. Two classes of neutrosophic norm (n-norm) and neutrosophic conorm (n-conorm) are defined. Examples of applications of neutrosophic logic to physics are listed in the last section. Similar generalizations can be done for n-Valued Refined Neutrosophic Set, …

On Improvement In Estimating Population Parameter(S) Using Auxiliary Information, Florentin Smarandache, Rajesh Singh

Branch Mathematics and Statistics Faculty and Staff Publications

The purpose of writing this book is to suggest some improved estimators using auxiliary information in sampling schemes like simple random sampling and systematic sampling. This volume is a collection of five papers, written by eight coauthors (listed in the order of the papers): Manoj K. Chaudhary, Sachin Malik, Rajesh Singh, Florentin Smarandache, Hemant Verma, Prayas Sharma, Olufadi Yunusa, and Viplav Kumar Singh, from India, Nigeria, and USA. The following problems have been discussed in the book: In chapter one an estimator in systematic sampling using auxiliary information is studied in the presence of non-response. In second chapter some improved …

Correlation Coefficient Of Interval Neutrosophic Set, Said Broumi, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper we introduce for the first time the concept of correlation coefficients of interval valued neutrosophic set (INS for short). Respective numerical examples are presented.

Mathematical Analysis Of The Problems Faced By The People With Disabilities (Pwds), Florentin Smarandache, W.B. Vasantha Kandasamy, A. Praveen Prakash

Branch Mathematics and Statistics Faculty and Staff Publications

The authors in this book have analyzed the socio-economic and psychological problems faced by People with Disabilities (PWDs) and their families. The study was made by collecting data using both fuzzy linguistic questionnaire / by interviews in case they are not literates from 2,15,811 lakhs people. This data was collected using the five Non Government Organizations (NGOs) from northern Tamil Nadu. Now any reader would be interested to know whether the Tamils (natives of Tamil Nadu) had ever spoken about people with disability. Even before 2000 years tamils had heroic poetry Purananuru (28th poem) about the war fare methods. In …

A General Family Of Dual To Ratio-Cum-Product Estimator In Sample Surveys, Florentin Smarandache, Rajesh Singh, Mukesh Kumar, Pankaj Chauhan, Nirmala Sawan

Branch Mathematics and Statistics Faculty and Staff Publications

This paper presents a family of dual to ratio-cum-product estimators for the finite population mean. Under simple random sampling without replacement (SRSWOR) scheme, expressions of the bias and mean-squared error (MSE) up to the first order of approximation are derived. We show that the proposed family is more efficient than usual unbiased estimator, ratio estimator, product estimator, Singh estimator (1967), Srivenkataramana (1980) and Bandyopadhyaya estimator (1980) and Singh et al. (2005) estimator. An empirical study is carried out to illustrate the performance of the constructed estimator over others.

Studies In Sampling Techniques And Time Series Analysis, Florentin Smarandache, Rajesh Singh

Branch Mathematics and Statistics Faculty and Staff Publications

This book has been designed for students and researchers who are working in the field of time series analysis and estimation in finite population. There are papers by Rajesh Singh, Florentin Smarandache, Shweta Maurya, Ashish K. Singh, Manoj Kr. Chaudhary, V. K. Singh, Mukesh Kumar and Sachin Malik. First chapter deals with the problem of time series analysis and the rest of four chapters deal with the problems of estimation in finite population. The book is divided in five chapters as follows: Chapter 1. Water pollution is a major global problem. In this chapter, time series analysis is carried out …

Uniform And Partially Uniform Redistribution Rules, Florentin Smarandache, Jean Dezert

Branch Mathematics and Statistics Faculty and Staff Publications

This short paper introduces two new fusion rules for combining quantitative basic belief assignments. These rules although very simple have not been proposed in literature so far and could serve as useful alternatives because of their low computation cost with respect to the recent advanced Proportional Conflict Redistribution rules developed in the DSmT framework.

Some Ratio Type Estimators Under Measurement Errors, Florentin Smarandache, Mukesh Kumar, Rajesh Singh, Ashish K. Singh

Branch Mathematics and Statistics Faculty and Staff Publications

This article addresses the problem of estimating the population mean using auxiliary information in the presence of measurement errors.

Development Of Scoring Rubrics And Pre-Service Teachers Ability To Validate Mathematical Proofs, Timothy J. Middleton

Mathematics & Statistics ETDs

The basic aim of this exploratory research study was to determine if a specific instructional strategy, that of developing scoring rubrics within a collaborative classroom setting, could be used to improve pre-service teachers facility with proofs. During the study, which occurred in a course for secondary mathematics teachers, the primary focus was on creating and implementing a scoring rubric, rather than on direct instruction about proofs. In general, the study had very mixed results. Statistically, the quantitative data indicated no significant improvement occurred in participants' ability to validate proofs. However, the qualitative results and the considerable improvement by some participants …

Transmission Dynamics Of Avian Influenza Among Poultry With And Without Vaccination, Qiao Liang

Mathematics & Statistics ETDs

The continuing avian influenza (AI) out break that began in late 2003 and early 2004 has been disastrous for the poultry industry worldwide. It has resulted in severe socio-economic damage, and it has raised serious concerns for general public health. In this research, we use mathematics to analyze transmission dynamics of AI among poultry. We use a status-based approach to construct systems of differential equations to describe virus transmission dynamics. We develop theoretical means to eradicate the spread of the disease, and we calculate the size of healthy and infected populations during an AI outbreak, and the final population size …

Computational Modeling In Applied Problems: Collected Papers On Econometrics, Operations Research, Game Theory And Simulation, Florentin Smarandache, Sukanto Bhattacharya, Mohammad Khoshnevisan

Branch Mathematics and Statistics Faculty and Staff Publications

Computational models pervade all branches of the exact sciences and have in recent times also started to prove to be of immense utility in some of the traditionally 'soft' sciences like ecology, sociology and politics. This volume is a collection of a few cuttingedge research papers on the application of variety of computational models and tools in the analysis, interpretation and solution of vexing real-world problems and issues in economics, management, ecology and global politics by some prolific researchers in the field.

Proceedings Of The First International Conference On Neutrosophy, Neutrosophic Logic, Neutrosophic Set, Neutrosophic Probability And Statistics, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In 1960s Abraham Robinson has developed the non-standard analysis, a formalization of analysis and a branch of mathematical logic, that rigorously defines the infinitesimals. Informally, an infinitesimal is an infinitely small number. Formally, x is said to be infinitesimal if and only if for all positive integers n one has xxx < 1/n. Let &>0 be a such infinitesimal number. The hyper-real number set is an extension of the real number set, which includes classes of infinite numbers and classes of infinitesimal numbers. Let’s consider the non-standard finite numbers 1+ = 1+&, where “1” is its standard part and “&” its non-standard part, …