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Full-Text Articles in Statistics and Probability

Oral Sulopenem And Tebipenem For Complicated Urinary Tract Infection And Pyelonephritis In Patients With Extended-Spectrum Beta-Lactamase (Esbl)-Producing Gram Negative, Susceptible Bacteria, Daniel J. Yang, Thanh-Liem Vu, Landon Olsen, Aiyi Chen, H Stephen Lee Feb 2023

Oral Sulopenem And Tebipenem For Complicated Urinary Tract Infection And Pyelonephritis In Patients With Extended-Spectrum Beta-Lactamase (Esbl)-Producing Gram Negative, Susceptible Bacteria, Daniel J. Yang, Thanh-Liem Vu, Landon Olsen, Aiyi Chen, H Stephen Lee

Annual Research Symposium

ESBL-producing gram negative Enterobacteria is becoming more prevalent, and carbapenems play a key role in combating against ESBL for complicated urinary tract infections (cUTI). However, carbapenems are only available intravenously in the U.S. FDA is currently reviewing the newly developed oral carbapenems (sulopenem and tebipenem) and have requested additional clinical trial information before granting approval for cUTI. Currently available phase 3 clinical trials for tebipenem and sulopenem are reviewed.


Focus Group Interview Experience Of A University Clinical Research Team, Kade Janes Feb 2023

Focus Group Interview Experience Of A University Clinical Research Team, Kade Janes

Annual Research Symposium

No abstract provided.


Development Of A Census Driven Equation To Predict Non-Billable "Cross-Cover" Work Done During Nocturnist Shifts To Predict Staffing, Bibhash Neupane Feb 2023

Development Of A Census Driven Equation To Predict Non-Billable "Cross-Cover" Work Done During Nocturnist Shifts To Predict Staffing, Bibhash Neupane

Annual Research Symposium

No abstract provided.


Roseman Research Symposium, Manas Mandal Feb 2023

Roseman Research Symposium, Manas Mandal

Annual Research Symposium

No abstract provided.


Vital Pulp Therapy: “What’S New When Visiting An Old Friend”?, John Francis Wisniewski Feb 2023

Vital Pulp Therapy: “What’S New When Visiting An Old Friend”?, John Francis Wisniewski

Annual Research Symposium

Roseman Health Sciences Research Symposium


Emergence Of Dental Nanomaterials: “Their Role In Performing Endodontic Therapy”, Chandrika Nama, John Wisniewski Dr. Feb 2023

Emergence Of Dental Nanomaterials: “Their Role In Performing Endodontic Therapy”, Chandrika Nama, John Wisniewski Dr.

Annual Research Symposium

No abstract provided.


The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang Feb 2023

The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang

Annual Research Symposium

No abstract provided.


New Year, New Variant Or A Subvariant Of Old Omicron?, Parker Grossman, Manas Mandal Feb 2023

New Year, New Variant Or A Subvariant Of Old Omicron?, Parker Grossman, Manas Mandal

Annual Research Symposium

No abstract provided.


Adverse Infusion-Related Event Severity In Oncology Patients Receiving Chemotherapy Agents Vs. Immunotherapy Agents, Tayler Hutto Feb 2023

Adverse Infusion-Related Event Severity In Oncology Patients Receiving Chemotherapy Agents Vs. Immunotherapy Agents, Tayler Hutto

Annual Research Symposium

In recent years, immunotherapy investigational drugs in cancer research has been underway in treating multiple forms of cancer due to a lower side effect profile and decreased severe infusion-reaction risk compared to conventional chemotherapy agents. The purpose of this study was to determine the infusion reaction severity among patients receiving either chemotherapy treatment or immunotherapy agents based on the CTCAE (Common Terminology Criteria for Adverse Events) scale to improve patient care outcomes.

In this intent-to-treat, retrospective observational study, a survey of patients throughout 10 Intermountain Healthcare infusion clinics was conducted to obtain documentation on patients who had received chemotherapy and/or …


Presentation Of Paired P- And Q-Arm Mosaic Deletions On Chromosome 18 Associated With Neuropsychiatric Symptoms, Jackson Nielsen, Laura Minor, John Dougherty Jr., Paige Moore, Kailee Edwards, Brandon Burrell, Jameson Williams, John A. Kriak, David W. Sant, Kyle B. Bills Feb 2023

Presentation Of Paired P- And Q-Arm Mosaic Deletions On Chromosome 18 Associated With Neuropsychiatric Symptoms, Jackson Nielsen, Laura Minor, John Dougherty Jr., Paige Moore, Kailee Edwards, Brandon Burrell, Jameson Williams, John A. Kriak, David W. Sant, Kyle B. Bills

Annual Research Symposium

No abstract provided.


Hypoglycemia: A Mimic Of Global Ischemic Injury, Zachary Leavitt, Jay Babu, Sannah Vasaya, Robert Balsinger, Aroucha Vickers Feb 2023

Hypoglycemia: A Mimic Of Global Ischemic Injury, Zachary Leavitt, Jay Babu, Sannah Vasaya, Robert Balsinger, Aroucha Vickers

Annual Research Symposium

No abstract provided.


Myolipoma Of The Eye Associate With Giant Fornix Syndrome, Trevor Jurges, Taylor Silva Feb 2023

Myolipoma Of The Eye Associate With Giant Fornix Syndrome, Trevor Jurges, Taylor Silva

Annual Research Symposium

This is our poster submission for the research symposium


Clinical Effects Of Lactobacillus Reuteri Probiotic In The Treatment Of Chronic Periodontitis: A Systematic Review Of Randomized Controlled Trials, Josephine Ram, Shilpa Bhandi, Kamran H. Awan, Frank Licari, Shankargouda Patil Feb 2023

Clinical Effects Of Lactobacillus Reuteri Probiotic In The Treatment Of Chronic Periodontitis: A Systematic Review Of Randomized Controlled Trials, Josephine Ram, Shilpa Bhandi, Kamran H. Awan, Frank Licari, Shankargouda Patil

Annual Research Symposium

No abstract provided.


Osteosarcoma Of The Breast, Jake Robins, Adira Ray, Yuna Jensen Feb 2023

Osteosarcoma Of The Breast, Jake Robins, Adira Ray, Yuna Jensen

Annual Research Symposium

We present a case report of a rare malignancy, primary osteosarcoma of the breast.


Intraosseous Hibernoma: Case Report And Review Of Current Literature, Eric Liou, Abdul Moiz Khan, Mosira Luekenga Feb 2023

Intraosseous Hibernoma: Case Report And Review Of Current Literature, Eric Liou, Abdul Moiz Khan, Mosira Luekenga

Annual Research Symposium

No abstract provided.


The Effect Of Augmented Reality Feature Of Complete Anatomy Application On Educational Outcomes In Students With Autism Spectrum Disorder, Anagha Sanne Feb 2023

The Effect Of Augmented Reality Feature Of Complete Anatomy Application On Educational Outcomes In Students With Autism Spectrum Disorder, Anagha Sanne

Annual Research Symposium

No abstract provided.


Nurse Educator Transition Into Academia-Lived Experience, Marika Chunyk, Marife Aczon-Armstrong Feb 2023

Nurse Educator Transition Into Academia-Lived Experience, Marika Chunyk, Marife Aczon-Armstrong

Annual Research Symposium

No abstract provided.


Examining Current Resources Available For Stroke Caregivers, Andrew Barlow Feb 2023

Examining Current Resources Available For Stroke Caregivers, Andrew Barlow

Annual Research Symposium

No abstract provided.


Association Between Vitamin D And Cardiovascular Disease: Findings From A National Study, Monica Ocampo, Amir Mohajeri, Man Hung Feb 2023

Association Between Vitamin D And Cardiovascular Disease: Findings From A National Study, Monica Ocampo, Amir Mohajeri, Man Hung

Annual Research Symposium

ABSTRACT

Introduction

Many studies have investigated the association between vitamin D and cardiovascular disease (CVD), but literature has shown various results. The aim of this study was to investigate the role of vitamin D in CVD.

Methods

Data source

The data were obtained from the 2015-2018 National Health and Nutrition Examination Survey database and included adults aged 20 years and older with a history of CVD. Descriptive statistics for participants’ demographics, vitamin D levels, CVD status, and risk factors were reported. Chi-square tests and t-tests were performed to examine differences in participant characteristics among those who had CVD and did …


Early Marriage And Reproductive Health Outcomes Among Women In South Asia, Sameen Kazmi Feb 2023

Early Marriage And Reproductive Health Outcomes Among Women In South Asia, Sameen Kazmi

Annual Research Symposium

No abstract provided.


Association Of Asthma With Oral Health In Different Age Groups, Jody Chiang, Amir Mohajeri, Joseph Cheever, Frank Licari, Man Hung Feb 2023

Association Of Asthma With Oral Health In Different Age Groups, Jody Chiang, Amir Mohajeri, Joseph Cheever, Frank Licari, Man Hung

Annual Research Symposium

No abstract provided.


Covid-19 Safety Protocol Communication From School: Dental Students' Experience, Daniel Yevseyevich Feb 2023

Covid-19 Safety Protocol Communication From School: Dental Students' Experience, Daniel Yevseyevich

Annual Research Symposium

Survey of Dental students' experience of COVID-19 Safety protocols


Comparison Of Radiographic Exposure During Rct Using Wall Mounted Units Vs Nomad Mobile Units: A Retrospective Study, Mason Smith, Benjamin Ricks Feb 2023

Comparison Of Radiographic Exposure During Rct Using Wall Mounted Units Vs Nomad Mobile Units: A Retrospective Study, Mason Smith, Benjamin Ricks

Annual Research Symposium

Roseman Research Symposium


Fit Assessment Of Soft Milled Co-Cr And Zirconia Fixed Dental Prosthesis Compared To Cast Co-Cr., Elie E. Daou Prof Feb 2023

Fit Assessment Of Soft Milled Co-Cr And Zirconia Fixed Dental Prosthesis Compared To Cast Co-Cr., Elie E. Daou Prof

Annual Research Symposium

No abstract provided.


Massachusetts Prevalence Of Opioid Use Disorder Estimation Revisited: Comparing A Bayesian Approach To Standard Capture-Recapture Methods, Jianing Wang, Nathan Doogan, Katherine L. Thompson, Dana Bernson, Daniel Feaster, Jennifer Villani, Redonna Chandler, Laura F. White, David Kline, Joshua A. Barocas Jan 2023

Massachusetts Prevalence Of Opioid Use Disorder Estimation Revisited: Comparing A Bayesian Approach To Standard Capture-Recapture Methods, Jianing Wang, Nathan Doogan, Katherine L. Thompson, Dana Bernson, Daniel Feaster, Jennifer Villani, Redonna Chandler, Laura F. White, David Kline, Joshua A. Barocas

Statistics Faculty Publications

Background: The National Survey on Drug Use and Health (NSDUH) estimated the prevalence of opioid use disorder (OUD) among the civilian, noninstitutionalized people aged 12 years or older in Massachusetts as 1.2% between 2015 and 2017. Accurate estimation of the prevalence of OUD is critical to the success of treatment and resource planning. Various indirect estimation approaches have been used but are subject to data availability and infrastructure-related issues.

Methods: We used 2015 data from the Massachusetts Public Health Data Warehouse (PHD) to compare the results of two approaches to estimating OUD prevalence in the Massachusetts population. First, we used …


Turnover, Covid-19, And Reasons For Leaving And Staying Within Governmental Public Health, Jonathan P. Leider, Gulzar H. Shah, Valerie A. Yeager, Jingjing Yin, Kusuma Madamala Jan 2023

Turnover, Covid-19, And Reasons For Leaving And Staying Within Governmental Public Health, Jonathan P. Leider, Gulzar H. Shah, Valerie A. Yeager, Jingjing Yin, Kusuma Madamala

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Background and Objectives:

Public health workforce recruitment and retention continue to challenge public health agencies. This study aims to describe the trends in intention to leave and retire and analyze factors associated with intentions to leave and intentions to stay.

Design:

Using national-level data from the 2017 and 2021 Public Health Workforce Interests and Needs Surveys, bivariate analyses of intent to leave were conducted using a Rao-Scott adjusted chi-square and multivariate analysis using logistic regression models.

Results:

In 2021, 20% of employees planned to retire and 30% were considering leaving. In contrast, 23% of employees planned to retire and 28% …


Striving For Appropriate Antibiotic Use: A Biomarker Initiative, And Outcomes Associated With Azithromycin Exposure, Amanda Gusovsky Jan 2023

Striving For Appropriate Antibiotic Use: A Biomarker Initiative, And Outcomes Associated With Azithromycin Exposure, Amanda Gusovsky

Theses and Dissertations--Pharmacy

The introduction of antibiotics into clinical practice is considered the greatest medical breakthrough of the 20thcentury. However, the use of antibiotics can contribute to the development of resistance. In the United States (U.S.), approximately 2.8 million people are infected with antibiotic-resistant bacteria each year, and more than 35,000 people die as a result. Moreover, some antibiotics are known to cause cardiac side effects including QT prolongation, hypotension, and ventricular arrythmias. The U.S. Centers for Disease Control and Prevention (CDC) defines appropriate antibiotic use as the effort to use “the right antibiotic, at the right dose, for the right …


Clustering Hospital Performance Using Group-Based Multi-Trajectory Modeling With Singular Bayesian Information Criterion, Gaixin Du Jan 2023

Clustering Hospital Performance Using Group-Based Multi-Trajectory Modeling With Singular Bayesian Information Criterion, Gaixin Du

Theses and Dissertations--Epidemiology and Biostatistics

Hospital performance is complex and patient-experience oriented. Currently, the Centers for Medicare and Medicaid Services (CMS) evaluate hospitals yearly with a single score of one to five ("Star Rating") using composite measures from five domains. However, a single composite score cannot fully describe it, and alternative measures should be considered. Healthcare quality improvement needs long-term data to validate effectiveness. Group-based multi-trajectory modeling (GBMTM) estimates probabilities of latent group membership based on longitudinal profiles from multiple outcomes. We use GBMTM to identify groups of hospitals with similar performance in SAS PROC TRAJ.

We downloaded Medicare-eligible hospitals (N=5,111) that provided patient care …


Potential Alzheimer's Disease Plasma Biomarkers, Taylor Estepp Jan 2023

Potential Alzheimer's Disease Plasma Biomarkers, Taylor Estepp

Theses and Dissertations--Epidemiology and Biostatistics

In this series of studies, we examined the potential of a variety of blood-based plasma biomarkers for the identification of Alzheimer's disease (AD) progression and cognitive decline. With the end goal of studying these biomarkers via mixture modeling, we began with a literature review of the methodology. An examination of the biomarkers with demographics and other health factors found evidence of minimal risk of confounding along the causal pathway from biomarkers to cognitive performance. Further study examined the usefulness of linear combinations of biomarkers, achieved via partial least squares (PLS) analysis, as predictors of various cognitive assessment scores and clinical …


Poisson Regression Model With Application To Wastewater Surveillance Under A Threshold Linear Mixed Model For Covid-19 Sensitivity Rates, Norou Diawara, Hueiwang Anna Jeng, Kyle Curtis, Raul Gonzalez, Nancy Welch, Cynthia Jackson, Rekha Singh, David Jurgens, Sasanka Adikari, Omotomilola Jegede Jan 2023

Poisson Regression Model With Application To Wastewater Surveillance Under A Threshold Linear Mixed Model For Covid-19 Sensitivity Rates, Norou Diawara, Hueiwang Anna Jeng, Kyle Curtis, Raul Gonzalez, Nancy Welch, Cynthia Jackson, Rekha Singh, David Jurgens, Sasanka Adikari, Omotomilola Jegede

Mathematics & Statistics Faculty Publications

A Threshold Linear Mixed Model (TLMM) has been developed to identify specific thresholds based on wastewater SARS-CoV-2 viral concentrations, which reflect COVID-19 cases. The thresholds can guide decisions regarding public health responses and prevention measures. To assess the practical application of TLMM, a simple simulation was conducted using a sample size of 100 and 500 replications. The simulation allowed for comparing parameter estimators by assessing bias and standard deviation and the root of the mean square error. The model and estimation procedures were applied to reported wastewater and clinic data to test its application for real-world scenarios. Our results demonstrated …