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Full-Text Articles in Physics
Monitoring And Identifying The Rhodamine 6g-Hydroxide Ion Reaction Using In-Situ, Surface-Enhanced Raman Spectroscopy, Ryan Lamb
Masters Theses & Specialist Projects
An effective method for monitoring chemical reactions is necessary to better understand their mechanisms and kinetics. Effective reaction monitoring requires a spectroscopy technique with fast data acquisition, high sensitivity, structure-to-spectrum correlation, and low solvent interference. Surface-enhanced Raman spectroscopy (SERS) provides these features, which makes it a valuable tool for monitoring reactions. To obtain the Raman enhancement, metallic nanostructures typically made of silver or gold are aggregated using a salt. The nanoparticles aggregates must then be stabilized using a surfactant to use this method in situ due to eventual nanoparticle precipitation. In this study, gold nanoparticles stabilized with sodium dodecyl sulfate …
Liposomal Encapsulation Of Silver Nanoparticles To Enhance Nanoparticle Cytotoxicity And Modulate Induced Inflammatory Responses In Vitro, Azeez Yusuf
Doctoral
High concentrations of silver nanoparticles (AgNP) are increasingly present as active ingredient in everyday consumable products for antibacterial purposes causing increased human exposure and high risk of adverse effect development. In this thesis, AgNP were encapsulated in dipalmitoyl phosphatidylcholine (DPPC)-based liposome (forming Lipo-AgNP), to enhance intracellular delivery and associated cytotoxicity, and suppress AgNP-induced inflammation. It was noted that as a result of the encapsulation, Lipo-AgNP induced significantly reduced cell viability of THP1 monocytes and THP1 differentiated macrophages (TDM) at a notably lower dose than that of uncoated AgNP. The induced cytotoxicity was shown to result in an increased level of …