Mathematics Commons^™

Going Beyond Promoting: Preparing Students To Creatively Solve Future Problems, Kristin M. Arney, Kayla K. Blyman, Jennifer D. Cepeda, Scott A. Lynch, Michael J. Prokos, Scott Warnke

Journal of Humanistic Mathematics

While we cannot know what problems the future will bring, we can be almost certain that solving them will require creativity. In this article we describe how our course, a first-year undergraduate mathematics course, supports creative problem solving. Creative problem solving cannot be learned through a single experience, so we provide our students with a blend of experiences. We discuss how the course structure enables creative problem solving through class instruction, during class activities, during out of class assessments, and during in class assessments. We believe this course structure increases student comfort with solving open-ended and ill-defined problems similar to …

Phase-Adjusted Estimation Of The Covid-19 Outbreak In South Korea Under Multi-Source Data And Adjustment Measures: A Modelling Study, Xiaomei Feng, Jing Chen, Kai Wang, Lei Wang, Fengqin Zhang, Zhen Jin, Lan Zou, Xia Wang

Mathematics Faculty Articles

Based on the reported data from February 16, 2020 to March 9, 2020 in South Korea including confirmed cases, death cases and recovery cases, the control reproduction number was estimated respectively at different control measure phases using Markov chain Monte Carlo method and presented using the resulting posterior mean and 95% credible interval (C_rI). At the early phase from February 16 to February 24, we estimate the basic reproduction number R₀ of COVID-19 to be 4.79(95% C_rI 4.38 - 5.2). The estimated control reproduction number dropped rapidly to R_c ≈ 0.32(95% C_rI …

Comparison Of Non-Prosthetic And Prosthetic Strides In A Pendulum-Based Model, Catherine T. Cronister

Student Scholarship

In this paper, we explore the differences in a non-prosthetic and prosthetic single stride. We accomplish this by developing a model based on a forced, triple pendulum. We use this model to describe a single stride and alter where the internal force comes from to simulate a prosthetic and non-prosthetic stride. We numerically solve our model with Matlab. We find that our model qualitatively represents the energy gap between a prosthetic and non-prosthetic stride. Our model also agreed qualitatively with alterations of the prosthetic designed to decrease the energy gap between the two strides.

Making Real-World Connections In High School Mathematics: The Effectiveness Of A Professional Development Program In Changing Teachers’ Knowledge, Beliefs, And Practices, Thad Ludlam Wilhelm

Wayne State University Dissertations

The study aimed to assess the impact of a professional development workshop at changing secondary mathematics teachers’ knowledge, beliefs, and practices related to real-world applications of algebra. It also addressed gaps in the research literature related to teacher knowledge of how algebra is used by professionals in non-academic settings and their beliefs about the relevance of algebra to their students’ lives. The observational study employed mixed methods. Principal components analysis was conducted on responses to an online questionnaire. Pre-test vs. post-test comparisons were made for workshop participants. Treatment vs. control comparisons were also made using a nationally representative random sample …

Formation Of Escherichia Coli O157: H7 Persister Cells In The Lettuce Phyllosphere And Application Of Differential Equation Models To Predict Their Prevalence On Lettuce Plants In The Field, Daniel S. Munther, Michelle Q. Carter, Claude V. Aldric, Renata Ivanek, Maria T. Brandl

Mathematics and Statistics Faculty Publications

American Society for Microbiology. Escherichia coli O157:H7 (EcO157) infections have been recurrently associated with produce. The physiological state of EcO157 cells surviving the many stresses encountered on plants is poorly understood. EcO157 populations on plants in the field generally follow a biphasic decay in which small subpopulations survive over longer periods of time. We hypothesized that these subpopulations include persister cells, known as cells in a transient dormant state that arise through phenotypic variation in a clonal population. Using three experimental regimes (with growing, stationary at carrying capacity, and decaying populations), we measured the persister cell fractions in culturable EcO157 …

An Individual-Carcass Model For Quantifying Bacterial Cross-Contamination In An Industrial Three-Stage Poultry Scalding Tank, Zachary Mccarthy, Ben Smith, Aamir Fazil, Shawn D. Ryan, Jianhong Wu, Daniel Munther

Mathematics and Statistics Faculty Publications

No abstract provided.

Examining Students’ Covariational Reasoning Through Mathematical Modeling Activities Embedded In The Context Of The Greenhouse Effect, Debasmita Basu

Theses, Dissertations and Culminating Projects

The greenhouse effect is one of the most pressing environmental as well as social issues of the present age. In news media and weather reports, most of the essential information about the phenomenon is expressed in forms of graphs and pictures. However, the interpretation of such graphs is challenging for students; they often focus on the shape of the graphs, overlooking the covariational relationships between the concerned quantities. Building on the framework of critical mathematics literacy and social justice mathematics, in this study I aimed to explore the power of dynamic mathematical modeling activities for engaging students in covariational reasoning …

Ph Dependent C-Jejuni Thermal Inactivation Models And Application To Poultry Scalding, Zachary Mccarthy, Ben Smith, Aamir Fazil, Jianhong Wu, Shawn D. Ryan, Daniel Munther

Mathematics and Statistics Faculty Publications

Campylobacter jejuni related outbreaks and prevalence on retail poultry products pose threats to public health and cause financial burden worldwide. To resolve these problems, it is imperative to take a closer look at poultry processing practices and standards. Using available data (D-values) on the thermal inactivation of C. jejuni we develop a comprehensive inactivation model, taking into account the variation of strain-specific heat resistance, experimental method, and suspension pH. Utilizing our C. jejuni thermal inactivation model, we study the poultry scalding process. We present a mechanistic model of bacteria transfer and inactivation during a typical immersion scald in a high-speed …

Mathematical Modeling Of Type 1 Diabetes, Gianna Wu

HMC Senior Theses

Type 1 Diabetes (T1D) is an autoimmune disease where the pancreas produces little to no insulin, which is a hormone that regulates blood glucose levels. This happens because the immune system attacks (and kills) the beta cells of the pancreas, which are responsible for insulin production. Higher levels of glucose in the blood could have very negative, long term effects such as organ damage and blindness.

To date, T1D does not have a defined cause nor cure, and research for this disease is slow and difficult due to the invasive nature of T1D experimentation. Mathematical modeling provides an alternative approach …

Mathematical Modeling And Classroom Discourse: A Case For Modeling-Specific Discussion Strategies, Ashley Dorlack, Hyunyi Jung, Sarah Brand, Samuel Franklin Gailliot

Mathematical and Statistical Science Faculty Research and Publications

No abstract provided.

Mathematical Modeling Experiences: Narratives From A Preservice Teacher And An Instructor, Sarah Brand, Hyunyi Jung

Mathematical and Statistical Science Faculty Research and Publications

Regardless of the benefits of engaging in mathematical modeling, few preservice teachers (PTs) have experienced mathematical modeling firsthand. This study offers an example of how to make sense of the interaction between the teaching and learning of mathematical modeling by examining a teacher educator’s decision making, her analysis of 36 PTs’ learning, and an in-depth narrative from a PT. Findings show the value of engaging with structurally relevant mathematical modeling tasks and considering social issues via mathematical modeling, resulting in task designs which aim to deepen students’ understanding of society and mathematics.

Modeling The Spread Of Disease, James Hollister

Essential Studies UNDergraduate Showcase

Mathematically modeling the spread of disease in a population is a focus among epidemiologists. Using an SIR model (susceptible, infected, and recovered), we can create a system of differential equations to help better understand how a disease spreads in a simple environment. However, if we are to create a more realistic environment, computer simulations may be necessary. We can use the results from these simulations to try and find ways to eradicate the disease as efficiently as possible. In this poster, we will present the SIR model, present a system of differential equations that describe the movement of disease in …

Modeling Plant Virus Propagation And An Optimal Control, Mark Jackson

Mathematics Dissertations - Archive

Plants are a food source for man and many species. They also are sources of medicines, fibers for clothes, and are essential for a healthy environment. But plants are subject to diseases many of which are caused by viruses. These viruses often kill the plant. As a result, billions of dollars are lost every year because of virus related crop loss. Most of the time, virus propagation is done by a vector, usually insects that bite infected plants, get themselves infected and then bite susceptible plants. To combat the vectors, and ultimately the viruses, pesticides are often used as a …

Mathematical Models, Patty Wagner, Marnie Phipps

Mathematics Grants Collections

This Grants Collection for Mathematical Models was created under a Round Nine ALG Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

Simplicity And Sustainability: Pointers From Ethics And Science, Mehrdad Massoudi, Ashuwin Vaidya

Department of Mathematics Faculty Scholarship and Creative Works

In this paper, we explore the notion of simplicity. We use definitions of simplicity proposed by philosophers, scientists, and economists. In an age when the rapidly growing human population faces an equally rapidly declining energy/material resources, there is an urgent need to consider various notions of simplicity, collective and individual, which we believe to be a sensible path to restore our planet to a reasonable state of health. Following the logic of mathematicians and physicists, we suggest that simplicity can be related to sustainability. Our efforts must therefore not be spent so much in pursuit of growth but in achieving …

Evoked And Spontaneous Neurotransmitter Releases For Independent Synaptic Currents: Mathematical Modeling And Analysis, Sat Byul Seo

Mathematics Dissertations - Archive

Synapses play a major role in neuron communications in the brain. The synapses act through a chemical process called synaptic fusion between pre-synaptic and post-synaptic terminals. Presynaptic terminals release neurotransmitters either in response to action potential or spontaneously independent of presynaptic activity. In the case of glutamate, released neurotransmitters acivate N-methyl-D-asparate (NMDA) receptors within a single postsynaptic site and give rise to miniature postsynaptic currents. In this dissertation, we develop a mathematical model in 3-D to emulate spontaneous and evoked neurotransmissions resulted from glutamate release within a single synapse. We propose numerical methods for solving piecewise continuous heat diffusion equation, …

Network Modeling Of Infectious Disease: Transmission, Control And Prevention, Christina M. Chandler

Honors College Theses

Many factors come into play when it comes to the transmission of infectious diseases. In disease control and prevention, it is inevitable to consider the general population and the relationships between individuals as a whole, which calls for advanced mathematical modeling approaches.

We will use the concept of network flow and the modified Ford-Fulkerson algorithm to demonstrate the transmission of infectious diseases over a given period of time. Through our model one can observe what possible measures should be taken or improved upon in the case of an epidemic. We identify key nodes and edges in the resulted network, which …

A Three-Fold Approach To The Heat Equation: Data, Modeling, Numerics, Kimberly R. Spayd, James G. Puckett

Math Faculty Publications

This article describes our modeling approach to teaching the one-dimensional heat (diffusion) equation in a one-semester undergraduate partial differential equations course. We constructed the apparatus for a demonstration of heat diffusion through a long, thin metal rod with prescribed temperatures at each end. The students observed the physical phenomenon, collected temperature data along the rod, then referenced the demonstration for purposes in and out of the classroom. Here, we discuss the experimental setup, how the demonstration informed practices in the classroom and a project based on the collected data, including analytical and computational components.

Roles Of A Teacher And Researcher During In Situ Professional Development Around The Implementation Of Mathematical Modeling Tasks, Hyunyi Jung, Corey Brady

Mathematics, Statistics and Computer Science Faculty Research and Publications

Partnership with teachers for professional development has been considered beneficial because of the potential of collaborative work in the teacher’s own classroom to be relevant to practice. From this perspective, both teachers and researchers can draw on their own expertise and work as authentic partners. In this study, we address the need for such collaboration and focus on how a teacher and a researcher performed their roles when collaboratively implementing mathematical modeling tasks within a context of in situ professional development. Using multi-tier design-based research, as a framework, a researcher worked in a teacher’s classroom to implement a series of …

Supporting Teachers’ Learning About Mathematical Modeling, June L. Gastón, Barbara A. Lawrence

Publications and Research

In the United States, one of the Standards for Mathematical Practice of the Common Core Curriculum (Common Core State Standards Initiative, 2010) is Model with mathematics. This standard requires that students be taught in a manner that will enable them to ―apply the mathematics they know to solve problems arising in everyday life, society, and the workplace‖ (p. 7). However many prospective and practicing teachers acquire a pedagogical style that does not support this standard. To promote higher levels of student thinking associated with mathematical modeling, teachers must thus be taught not only what mathematical modeling is, but how it …

Course Proposal For A Mathematical Modeling Course In A High School Curriculum, Thomas P. Marlowe

Masters Essays

In the winter of 2015, I will be piloting a course on mathematical modeling at Hawken School, an independent high school in Gates Mills, OH. As I develop all elements of this course, such as lesson plans, assessments, and rubrics, I will be mindful of factors such as the newly adopted Common Core mathematics standards, the variety of student backgrounds in such a course, and how various mathematical societies and organizations such as SIAM, MAA, and COMAP can help in implementing it. However, there is one basic question driving my interest in and design of this course: “when am I …

Generalized Theoretical Criteria For Annihilation Of Hiv-1 Virions During Haart, Frank Nani, Mingxian Jin

Math and Computer Science Faculty Working Papers

Aims: This paper is an elaborate and quantitative attempt to construct medically applicable mathematical models and derive criteria for efficacious Highly Active Anti-Retroviral Therapy (HAART) protocol for an AIDS patient. The patho-physiological dynamics of Human Immuno-deficiency Virus type 1 (HIV-1) induced AIDS during HAART is modeled by a system of non-linear deterministic differential equations. The physiologically relevant and clinically plausible equations depict the dynamics of uninfected CD4+ T cells (x1), HIV-1 infected CD4+ T cells (x2), HIV-1 virions in the blood plasma (x3), HIV-1 specific CD8+ T cells (x4), and the concentration of HAART drug molecules (x5). The major objective …

Kif11 Dependent Cell Cycle Progression In Radial Glial Cells Is Required For Proper Neurogenesis In The Zebrafish Neural Tube, Kimberly Johnson, Chelsea Moriarty, Nessy Tania, Alissa Ortman, Kristina Dipietrantonio, Brittany Edens, Jean Eisenman, Deborah Ok, Sarah Krikorian, Jessica Barragan, Christophe Golé, Michael J.F. Barresi

Mathematics Sciences: Faculty Publications

Radial glia serve as the resident neural stem cells in the embryonic vertebrate nervous system, and their proliferation must be tightly regulated to generate the correct number of neuronal and glial cell progeny in the neural tube. During a forward genetic screen, we recently identified a zebrafish mutant in the kif11 loci that displayed a significant increase in radial glial cell bodies at the ventricular zone of the spinal cord. Kif11, also known as Eg5, is a kinesin-related, plus-end directed motor protein responsible for stabilizing and separating the bipolar mitotic spindle. We show here that Gfap+ radial glial cells express …

A Primer For Mathematical Modeling, Marla A. Sole

Publications and Research

With the implementation of the National Council of Teachers of Mathematics recommendations and the adoption of the Common Core State Standards for Mathematics, modeling has moved to the forefront of K-12 education. Modeling activities not only reinforce purposeful problem-solving skills, they also connect the mathematics students learn in school with the mathematics they will use outside of school. Instructors have found mathematical modeling difficult to teach. To successfully incorporate modeling activities I believe that curricular changes should be accompanied by professional development for curriculum developers, classroom teachers, and higher education professionals. This article serves as an introduction to modeling by …

Mathematical Modeling Of The Regulatory T Cell Effects On Renal Cell Carcinoma Treatment, Lisette G. De Pillis, Trevor Caldwell '12, Elizabeth Sarapata '13, Heather Williams '12

All HMC Faculty Publications and Research

We present a mathematical model to study the effects of the regulatory T cells (Treg) on Renal Cell Carcinoma (RCC) treatment with sunitinib. The drug sunitinib inhibits the natural self-regulation of the immune system, allowing the effector components of the immune system to function for longer periods of time. This mathematical model builds upon our non-linear ODE model by de Pillis et al. (2009) [13] to incorporate sunitinib treatment, regulatory T cell dynamics, and RCC-specific parameters. The model also elucidates the roles of certain RCC-specific parameters in determining key differences between in silico patients whose immune profiles allowed them to …

The Mathematics Of A Successful Deconvolution: A Quantitative Assessment Of Mixture-Based Combinatorial Libraries Screened Against Two Formylpeptide Receptors, Radleigh Santos, Jon R. Appel, Marc Giulianotti, Bruce S. Edwards, Larry A. Sklar, Richard A. Houghten, Clemencia Pinilla

Mathematics Faculty Articles

In the past 20 years, synthetic combinatorial methods have fundamentally advanced the ability to synthesize and screen large numbers of compounds for drug discovery and basic research. Mixture-based libraries and positional scanning deconvolution combine two approaches for the rapid identification of specific scaffolds and active ligands. Here we present a quantitative assessment of the screening of 32 positional scanning libraries in the identification of highly specific and selective ligands for two formylpeptide receptors. We also compare and contrast two mixture-based library approaches using a mathematical model to facilitate the selection of active scaffolds and libraries to be pursued for further …

Social Aggregation In Pea Aphids: Experiment And Random Walk Modeling, Christa Nilsen, John Paige, Olivia Warner, Benjamin Mayhew, Ryan Sutley, Matthew Lam '15, Andrew J. Bernoff, Chad M. Topaz

All HMC Faculty Publications and Research

From bird flocks to fish schools and ungulate herds to insect swarms, social biological aggregations are found across the natural world. An ongoing challenge in the mathematical modeling of aggregations is to strengthen the connection between models and biological data by quantifying the rules that individuals follow. We model aggregation of the pea aphid, Acyrthosiphon pisum. Specifically, we conduct experiments to track the motion of aphids walking in a featureless circular arena in order to deduce individual-level rules. We observe that each aphid transitions stochastically between a moving and a stationary state. Moving aphids follow a correlated random walk. …

Mathematical Models Of Combustion At High Pressure, Daniel Fong

Dissertations

In this dissertation, we develop new mathematical theories of flame propagation that are valid at elevated, or extreme, pressures. Of particular interest is the regime of burning in which the pressure exceeds the critical pressure of the species undergoing chemical reaction. Fluids and flames are known to behave differently under these extreme conditions as opposed to atmospheric pressure. The focus of this dissertation is to investigate these differences by deriving reduced models that contain the unique features.

In the first part of this dissertation, we analyze the structure of laminar diffusion flames at high pressure in the limit of large …

Computational Modeling And Numerical Methods For Spaciotemporal Calcium Cycling In Ventricular Myocytes, Robert Rovetti

Mathematics, Statistics and Data Science Faculty Works

Intracellular calcium (Ca) cycling dynamics in cardiac myocytes is regulated by a complex network of spatially distributed organelles, such as sarcoplasmic reticulum (SR), mitochondria, and myofibrils. In this study, we present a mathematical model of intracellular Ca cycling and numerical and computational methods for computer simulations. The model consists of a coupled Ca release unit (CRU) network, which includes a SR domain and a myoplasm domain. Each CRU contains 10 L-type Ca channels and 100 ryanodine receptor channels, with individual channels simulated stochastically using a variant of Gillespie’s method, modified here to handle time-dependent transition rates. Both the SR domain …

Computational Modeling And Numerical Methods For Spatiotemporal Calcium Cycling In Ventricular Myocytes, Michael Nivala, Enno De Lange, Robert J. Rovetti, Zhilin Qu

Mathematics, Statistics and Data Science Faculty Works

Intracellular calcium (Ca) cycling dynamics in cardiac myocytes is regulated by a complex network of spatially distributed organelles, such as sarcoplasmic reticulum (SR), mitochondria, and myofibrils. In this study, we present a mathematical model of intracellular Ca cycling and numerical and computational methods for computer simulations. The model consists of a coupled Ca release unit (CRU) network, which includes a SR domain and a myoplasm domain. Each CRU contains 10 L-type Ca channels and 100 ryanodine receptor channels, with individual channels simulated stochastically using a variant of Gillespie’s method, modified here to handle time-dependent transition rates. Both the SR domain …