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Articles 1 - 30 of 2019
Full-Text Articles in Mathematics
Revisiting Ulam Stability For Boundary Value Problems, Martin Bohner, Snezhana Hristova, Agnieszka B. Malinowska, Ewa Girejko
Revisiting Ulam Stability For Boundary Value Problems, Martin Bohner, Snezhana Hristova, Agnieszka B. Malinowska, Ewa Girejko
Mathematics and Statistics Faculty Research & Creative Works
The main goal of this paper is to apply Ulam stability theory to boundary value problems for dynamic equations, while addressing several common misconceptions found in the existing literature. We identify the key issues that arise when applying Ulam stability to such problems and propose three distinct approaches to overcome them. To enhance clarity and accessibility, we begin with nonlinear ordinary differential equations and subsequently extend the analysis to nonlinear dynamic equations on time scales. Since a time scale is defined as any nonempty closed subset of the real numbers, our results are applicable to dynamic equations on continuous, discrete, …
Adaptive Rational Approximation In Dynamic Economic Models: A Novel Application Of The Aaa Algorithm To Economic Growth, Adaye Sosthene Yvan N'Guettia
Adaptive Rational Approximation In Dynamic Economic Models: A Novel Application Of The Aaa Algorithm To Economic Growth, Adaye Sosthene Yvan N'Guettia
Mathematics, Statistics, and Computer Science Honors Projects
I study adaptive rational approximation for fixed points that arise in infinite-horizon dynamic programming. I integrate the Adaptive Antoulas–Anderson (AAA) algorithm into Bellman- and Euler-based fixed-point solvers by recomputing a barycentric rational interpolant at each update. In addition to standard AAA, which selects support points from interpolation residuals, I study a residual-weighted variant in which Bellman,Euler, or KKT diagnostics act as secondary weights on the greedy pivot rule. This alignment of approximation adaptivity with the underlying equilibrium conditions can concentrate degrees of freedom in regions of steep curvature, sharp transitions in localbehavior, and other localized features that typically degrade polynomial …
An Analysis Of The Effects And Implementations Of The Early Literacy Grant In Arizona, Alicia Severiano Perez
An Analysis Of The Effects And Implementations Of The Early Literacy Grant In Arizona, Alicia Severiano Perez
Mathematics, Statistics, and Computer Science Honors Projects
Over the years, states have implemented Science of Reading (SoR) frameworks to address low literacy levels. The Early Literacy Grant (ELG) in Arizona funds and supports such frameworks for schools serving low-income students. This paper is the first to explore the grant through interrupted time series modeling to evaluate effectiveness and text analysis to understand its implementation. We do not find clear evidence of positive effects caused by the grant, other than some cases, such as Yuma County. Schools typically allocate funds toward salaries and hiring instructors. These findings raise questions about whether its allocations should be closely monitored.
Level Sets For Lehmer Codes Of Pattern Avoiding Permutations, Avery Sinclair
Level Sets For Lehmer Codes Of Pattern Avoiding Permutations, Avery Sinclair
Mathematics, Statistics, and Computer Science Honors Projects
We study the poset structures for two families of pattern avoiding permutations. An n-permutation is a list of the numbers [n]={1,2,...,n}. A permutation is 321-avoiding when it does not contain a decreasing subsequence of length 3. A poset (partially ordered set) is a set such that some elements can be compared with one another. Using Lehmer codes, we define a poset for 321-avoiding permutations. We then fully describe the six lowest levels of this poset. We then consider the analogous poset for 123-avoiding permutations (which don't contain an increasing subsequence of length 3) and fully describe the three lowest levels.
A Compact Representation Of Oscillatory Limits Via Asymptotic Value Distributions, Ibrahim Arnous, Eric M. Rodarte, Chirag Kumar
A Compact Representation Of Oscillatory Limits Via Asymptotic Value Distributions, Ibrahim Arnous, Eric M. Rodarte, Chirag Kumar
Discovery Day - Daytona Beach
Classical limits describe asymptotic behavior through convergence to a single value, but many important oscillatory functions do not converge in this sense. Standard examples such as sin(𝑥) as 𝑥→∞ and sin(1/x) as x→0 instead display stable distributions of values over time. This project examines how such behavior can be described using a measure-theoretic framework, particularly through occupation measures and, in sequence-based settings, Young measures. The objective is to present this perspective in a clear and accessible way while introducing the Ansatz representation, a compact notation for recording the support and density of an asymptotic value distribution when the limiting measure …
Machine Learning For Predictive Energy And Emissions Modeling Of Vehicles And Power Grids In The United States, S M Tanvir Faysal Alam Chowdhoury
Machine Learning For Predictive Energy And Emissions Modeling Of Vehicles And Power Grids In The United States, S M Tanvir Faysal Alam Chowdhoury
Dissertations
The environmental benefits of electric vehicle (EV) adoption depend on more than replacing internal combustion engine vehicles with electric powertrains. EV adoption reshapes electricity demand, interacts with regional generation mixes, and influences travel behavior and congestion, creating a coupled transportation-energy system in which vehicle and power-plant emissions must be evaluated together. This dissertation develops machine-learning frameworks for predicting energy consumption and emissions from vehicles and power grids under rising EV adoption. The first component forecasts grid emissions from EV charging. Using simulation data from NREL's Cambium database, a Prophet-based time-series framework predicts carbon dioxide, nitrous oxide, and methane emission rates …
Spatial Prediction Under Uncertainty: Methodological And Computational Advances In Bayesian Maximum Entropy, Kinspride K. Duah
Spatial Prediction Under Uncertainty: Methodological And Computational Advances In Bayesian Maximum Entropy, Kinspride K. Duah
All Graduate Theses and Dissertations, Fall 2023 to Present
Environmental decisions such as infrastructure design, water management, and snow load estimation depend on spatial data that are often incomplete or uncertain. In many cases, measurements are not exact values but ranges, reflecting limitations in data collection methods. Traditional mapping techniques typically simplify these uncertain measurements, which can lead to less accurate predictions. This dissertation introduces improved statistical tools for making spatial predictions when data are uncertain or partially known. By utilizing a framework called Bayesian Maximum Entropy (BME), this research demonstrates how exact measurements and range-based data can be combined in a mathematically consistent way. The work demonstrates that …
Learning Latent Structure In High-Dimensional Data Via Geometry And Graphs, Haozhe Chen
Learning Latent Structure In High-Dimensional Data Via Geometry And Graphs, Haozhe Chen
All Graduate Theses and Dissertations, Fall 2023 to Present
Modern datasets often contain many measured variables for each observation, such as gene-expression levels, brain activity signals, or features in tabular data. These data are also often noisy, meaning that useful patterns are mixed with measurement error or irrelevant variation. Although such datasets can appear complex, they are frequently represented by simpler hidden structures, such as trajectories, clusters, or relationships between observations. This dissertation develops methods for uncovering these hidden structures by learning geometric and graph-based representations directly from data. The first part introduces Functional Information Geometry, which represents local patterns in high-dimensional data using functional features and constructs a …
Unifying And Expanding Global And Local Variable Importance Methods For Explainable Machine Learning, Kelvyn K. Bladen
Unifying And Expanding Global And Local Variable Importance Methods For Explainable Machine Learning, Kelvyn K. Bladen
All Graduate Theses and Dissertations, Fall 2023 to Present
Machine learning methods are powerful analytical tools used across all scientific disciplines and many other fields of investigation for prediction and inference from diverse data sources. Despite their broad applicability, machine learning methods are often highly complex and difficult to interpret. Developing a greater understanding of which variables most influence a response is essential for increasing the interpretability of these models and supporting informed decision-making. This research focuses on improving how we evaluate the importance of these variables.
One common approach is to shuffle the values of a variable and see how much the model accuracy gets worse. Another approach …
Mapler: An R Package For Estimating The Impact Of Climate Change On Maple Syrup Production, Matthew T. White
Mapler: An R Package For Estimating The Impact Of Climate Change On Maple Syrup Production, Matthew T. White
All Graduate Theses and Dissertations, Fall 2023 to Present
Successful maple sap tapping depends on the freeze/thaw cycle (i.e., temperatures fluctuating above/below freezing) during the winter and spring. Climate change threatens to alter the timing and duration of the tapping season. This necessitates research into how maple sap tapping will be impacted by climate change in order to help maple syrup producers prepare for the future. We define a sap day as a day where the freeze/thaw cycle occurred. Using information climate scientists use to predict future temperatures, we calculate how many sap days could occur each year. We develop software to analyze these sap day calculations to determine …
Bias, Structure, And Inference In Applied Network Analysis, Anna Vasenina
Bias, Structure, And Inference In Applied Network Analysis, Anna Vasenina
Dartmouth College Ph.D Dissertations
This dissertation develops mathematical and statistical methods for extracting reliable information from network data across biological applications, with an emphasis on understanding what observed network structure can and cannot resolve. The first study leverages protein–protein interaction network topology in the c-di-GMP signaling system of Pseudomonas fluorescens, showing that node centrality measures accurately classify protein domain types and that physical interaction structure contributes statistically significant predictive power for biofilm formation phenotypes across nearly 200 environments, while gene expression does not. The second study examines sampling bias in lemur-plant trophic interaction networks in Madagascar, demonstrating that differential detection of diurnal versus …
A Copula-Based Framework For Multivariate Count Time Series With Mixed Marginal Distributions, Dimuthu Fernando, Yuxin Wen, Wimarsha Jayanetti
A Copula-Based Framework For Multivariate Count Time Series With Mixed Marginal Distributions, Dimuthu Fernando, Yuxin Wen, Wimarsha Jayanetti
Engineering Faculty Articles and Research
We developed a class of multivariate integer-valued time series models using copula theory. Each count time series is modeled as a Markov chain, with serial dependence characterized through copula-based transition probabilities for Poisson and negative binomial marginals. Cross-sectional dependence is modeled via a trivariate Gaussian or a “t-copula”, allowing for both positive and negative correlations and providing a flexible dependence structure. Model parameters are estimated using likelihood-based inference, where the trivariate Gaussian or t-copula integrals are evaluated through standard randomized Monte Carlo methods. Simulation results, along with an analysis of annual counts of major hurricanes (Category 3+) across the North …
Computational Insights Into Nucleosome Dynamics In Epigenetics Using Molecular Dynamics Simulations, Rutika Patel
Computational Insights Into Nucleosome Dynamics In Epigenetics Using Molecular Dynamics Simulations, Rutika Patel
Dissertations, Theses, and Capstone Projects
Nucleosome core particles (NCP) are the building blocks that form a highly organized and compact chromatin structure. Nucleosomes package DNA in the nucleus of eukaryotic cells. The NCP consists of about 147 base pairs of DNA wrapped around the histone octamer, with 1.65 superhelical turns in a left-handed manner. The histone octamer is composed of two copies of H3, H4, H2A, and H2B. Together with histone H1 and linker DNA, they further assemble into a higher-order chromatin structure. The nucleosome complex is stabilized by electrostatic interactions between positively charged histone residues and the negatively charged DNA backbone. To effectively access …
Measuring Stock Market Inefficiency Using A Multilayer Composite Efficiency Index: A Case Of The Egyptian Exchange, Patrick K. Owido, Hiroki Sayama
Measuring Stock Market Inefficiency Using A Multilayer Composite Efficiency Index: A Case Of The Egyptian Exchange, Patrick K. Owido, Hiroki Sayama
Northeast Journal of Complex Systems (NEJCS)
Financial markets play a critical role in resource allocation. Their performance depends on the decisions of millions of independent investors constantly reacting to one another. Their informational efficiency remains a subject of debate across economic systems. When informational efficiency is present at the weak form, historical price information should not consistently predict future returns. Several empirical tests of this hypothesis often focus on the behavior of aggregate market indices, and use individual efficiency proxies such as autocorrelation, GARCH-type volatility, or entropy-based measures to measure efficiency. This has often yielded mixed results, particularly in emerging markets. Here we show that testing …
Conditional Product Sampling For Gaussian Process Implicit Surfaces, Song Shi
Conditional Product Sampling For Gaussian Process Implicit Surfaces, Song Shi
Dartmouth College Master’s Theses
Gaussian Process Implicit Surfaces (GPISes) provide a powerful and unified stochastic geometry representation for rendering surfaces, volumes, and the rich continuum between them. Recent work has shown that GPISes can model a broad space of visual appearances under a unified light transport framework. However, practical rendering with GPISes remains challenging: existing estimators can become inefficient for particular correlation structures, and highly anisotropic or heightfield-like GPISes require specialized treatment to obtain robust variance reduction.
This thesis extends recent work on GPIS rendering by introducing a new next-event estimation (NEE) technique for anisotropic GPISes.We show that standard NEE provides diminishing benefits as …
Bayesian Designs For Two-Arm Clinical Trials With Time-To-Event Endpoints: Incorporating Historical Data Through Power Priors, Sara Hajraf H. Almutiri
Bayesian Designs For Two-Arm Clinical Trials With Time-To-Event Endpoints: Incorporating Historical Data Through Power Priors, Sara Hajraf H. Almutiri
Mathematics & Statistics ETDs
Bayesian methods provide a flexible framework for time-to-event analysis by incorporating prior information. The power prior offers a systematic way to borrow information from historical data. This approach is especially valuable in clinical research, where historical data can enhance inference in early-phase trials with limited sample sizes. This dissertation develops Bayesian approaches for two-arm survival studies using both closed-form and simulation-based methods. The closed-form inference is derived under exponential and Weibull survival models. Under the proportional hazards framework, the posterior is derived through a normal approximation to the log hazard ratio, allowing inference on the treatment effect when the variance …
A New Approach To Generate Combinatorial Patterns In Logical Analysis Of Data And Its Application To Predict College Retention, Salihah Ahmed E. Jaafari
A New Approach To Generate Combinatorial Patterns In Logical Analysis Of Data And Its Application To Predict College Retention, Salihah Ahmed E. Jaafari
Theses and Dissertations
Student retention and degree completion remain central challenges for higher-education institutions, with significant implications for student success, institutional effectiveness, and public accountability. While advances in predictive analytics have enabled earlier identification of students at risk of withdrawal, many commonly used machine learning approaches suffer from limited interpretability, constraining their practical usefulness for advising, intervention, and policy decision making. This dissertation addresses the problem of predicting student persistence by developing and evaluating optimization based, interpretable classification models within the Logical Analysis of Data (LAD) framework. Building on existing LAD formulations, this research introduces two novel pattern generation models, the Best Term …
Constraint-Aware Metaheuristic Optimization For Experimental Design, Benjamin N. Fuller
Constraint-Aware Metaheuristic Optimization For Experimental Design, Benjamin N. Fuller
All Graduate Theses and Dissertations, Fall 2023 to Present
Designing experiments becomes much more challenging when many variables and strict constraints are involved, as is common in modern science and engineering. This thesis introduces a new computational and mathematical framework that efficiently searches for optimal experiments in complex, high-dimensional spaces where traditional methods fail. By combining geometric techniques with flexible optimization algorithms like particle swarm optimization, our methods handle difficult constraints while scaling to real-world problems. Built in the high-performance Julia programming language and released as open-source software, this work bridges advanced theory with practical tools, offering researchers a powerful and accessible way to design better experiments under realistic …
Analyzing The Evolution Of Science: Topological Cycles And Community Detection In Knowledge Networks, Frances C. Mcconnell
Analyzing The Evolution Of Science: Topological Cycles And Community Detection In Knowledge Networks, Frances C. Mcconnell
Mathematics, Statistics, and Computer Science Honors Projects
How scientific knowledge grows and organizes itself is a central question in the study of science. This thesis uses tools from topology and network science to detect and characterize knowledge gaps—places in a field’s literature where related concepts do not co-occur. We develop a metric to quantify the degree of interdisciplinarity of each gap, using the community structure of the underlying network as a proxy for subfields. Across a wide range of fields, gaps reliably span multiple subfields and evolve in recognizable temporal patterns, highlighting new insights into how scientific fields are structured and their stage of development.
A Computer Vision Approach To Analyzing Taxane Effects On Prostate Cancer Cells, Diana Elizabeth Dancea
A Computer Vision Approach To Analyzing Taxane Effects On Prostate Cancer Cells, Diana Elizabeth Dancea
Electronic Theses and Dissertations
Actin is a family of proteins that help create the structure of the cytoskeleton, which gives shape to the cell. In many chemotherapy treatments, researchers target actin because it controls the cell division process. Therefore, if they are able to understand the actin fibers, that may help in formulating methods to stop or slow down cancer cells from reproducing. Another important protein is PAK6, which regulates actin. In our research, a collaborative effort with Prof. Michael Lu’s lab at Florida Atlantic University, we use machine learning techniques to analyze cells which had their PAK6 protein knocked out, and compare them …
Irreversible K-Threshold Dynamics On Corona And Base-B Corona Product Graphs, Eric J. Moon, Soumya Bhoumik, Paul Flesher
Irreversible K-Threshold Dynamics On Corona And Base-B Corona Product Graphs, Eric J. Moon, Soumya Bhoumik, Paul Flesher
SACAD: Scholarly Activities
This poster studies the irreversible k-threshold process on corona-type graph products, where a vertex becomes colored once at least k of its neighbors are colored and then remains colored permanently. We focus on corona, double corona, and base-b corona product graphs built from cycles and complete graphs, with particular attention to how graph structure affects complete activation from a minimum seed set.
A generalized reduction lemma is used to relate threshold dynamics on layered corona graphs to smaller residual graphs, yielding explicit formulas for the irreversible k-threshold conversion number on both corona and double corona families. The …
Sex-Specific Differences In Lung Mitochondrial Function And Injury In Rats Exposed To Hyperoxia, Taheri Pardis, Abraham G. Taye, Devanshi D. Dave, Elizabeth R. Jacobs, Guru Prasad Sharma, Anne V. Clough, Ranjan K. Dash, Said H. Audi
Sex-Specific Differences In Lung Mitochondrial Function And Injury In Rats Exposed To Hyperoxia, Taheri Pardis, Abraham G. Taye, Devanshi D. Dave, Elizabeth R. Jacobs, Guru Prasad Sharma, Anne V. Clough, Ranjan K. Dash, Said H. Audi
Mathematical and Statistical Science Faculty Research and Publications
Hyperoxia is both an essential therapy and a contributor to lung injury in acute respiratory distress syndrome. We hypothesized that adult female rats are relatively protected from hyperoxia-induced acute lung injury (HALI) compared with males and that this protection is associated with sex-dependent differences in lung mitochondrial bioenergetics and H2O2 production. Adult rats were exposed to room air (normoxia) or hyperoxia (>95% O2) for up to 60 h. Lung injury was assessed by pleural effusion, lung wet weight, pulmonary vascular filtration coefficient (Kf), histologic injury scores, and cleaved caspase-3 (CC3) staining. …
The Kaczmarz Algorithm In Hilbert C∗-Modules, Daniel Alpay, Chad Berner, Eric S. Weber
The Kaczmarz Algorithm In Hilbert C∗-Modules, Daniel Alpay, Chad Berner, Eric S. Weber
Mathematics and Statistics Faculty Research & Creative Works
The Kaczmarz algorithm in Hilbert spaces is a classical iterative method for stably recovering vectors from inner product data. In this paper, we extend the algorithm to the setting of Hilbert C∗-modules and establish analogues of its effectiveness in both finite-dimensional and stationary cases. Consequently, we demonstrate that continuous families of elements in a Hilbert space can be uniformly recovered using the Kaczmarz algorithm. Additionally, we develop a normalized Cauchy transform for continuous families of measures and use it to provide sufficient conditions under which standard frames in Hilbert C(X)-modules can be generated by the Kaczmarz algorithm and …
Sequences That Do Frame Reconstruction, Chad Berner
Sequences That Do Frame Reconstruction, Chad Berner
Mathematics and Statistics Faculty Research & Creative Works
Frames allow all elements of a Hilbert space to be reconstructed by inner product data in a stable manner. Recently, there is interest in relaxing the definition of frames to understand the implications for stable signal recovery. In this paper, we relax the definition of a frame by allowing the operator in the frame decomposition formula to not be invertible. We provide a complete classification of sequences that allow this decomposition via a type of frame operator. In addition, we provide several examples of sequences that allow this reconstruction property that are not frames and illustrate in which ways they …
Power Approximations With Non-Normal Data In Generalized Linear Mixed Models In R Using Steep Priors On Variance Components, Carlie Prinster, John Stevens
Power Approximations With Non-Normal Data In Generalized Linear Mixed Models In R Using Steep Priors On Variance Components, Carlie Prinster, John Stevens
Mathematics and Statistics Student Research and Class Projects
ENAR Spring 2026 Conference presentation on Power Approximations with Non-Normal Data in Generalized Linear Mixed Models in R Using Steep Priors on Variance Components
Automating Cardiff Model Data Capture In Emergency Departments: Ambient Nlp Integration With Oracle-Cerner Fhir Systems, Simi Augustine, Marco A. Lopez, Jacquelyn Cheun, Chris Papesh
Automating Cardiff Model Data Capture In Emergency Departments: Ambient Nlp Integration With Oracle-Cerner Fhir Systems, Simi Augustine, Marco A. Lopez, Jacquelyn Cheun, Chris Papesh
SMU Data Science Review
Violence and overdose events in Las Vegas occur at rates above the national average, with fewer than half of violent injuries reported to law enforcement [2,7]. The Cardiff Model offers a proven framework for standardized data collection and sharing between hospitals and public safety partners, yet many implementations still rely on manual entry. We propose an ambient triage pipeline integrated with Oracle-Cerner electronic health record systems to listen to nurse–patient dialogue, convert speech to text, extract Cardiff fields, and write standards-based FHIR Bundles for analytics. Using SMART on FHIR standards and Cerner Millennium APIs, the study evaluates whether ambient capture …
Averaging Principle For A General Class Of Periodic Functions In Discrete Spaces, Martin Bohner, Jaqueline G. Mesquita, Sabrina Streipert
Averaging Principle For A General Class Of Periodic Functions In Discrete Spaces, Martin Bohner, Jaqueline G. Mesquita, Sabrina Streipert
Mathematics and Statistics Faculty Research & Creative Works
In this work, we develop a periodic averaging principle for arbitrary discrete time domains, leveraging a novel definition of periodicity. This definition does not rely on the classical requirement for the time domain itself to be periodic. We implement this averaging principle across diverse discrete time domains and explore a range of periodic functions within this extended context. The paper contains several examples with numerical simulations, providing visual demonstrations of our results. This highlights the versatility of our averaging principle and its potential to understand dynamics of nonautonomous recurrences with complex temporal patterns.
Controllability Of The Semilinear Benjamin–Bona–Mahony Dynamic Equation On Homogeneous Time Scales, Martin Bohner, Cosme Duque, Hugo Leiva
Controllability Of The Semilinear Benjamin–Bona–Mahony Dynamic Equation On Homogeneous Time Scales, Martin Bohner, Cosme Duque, Hugo Leiva
Mathematics and Statistics Faculty Research & Creative Works
This work investigates the approximate controllability and free-time approximate controllability of a generalized semi linear Benjamin–Bona–Mahony type dynamic equation defined on homogeneous time scales, subject to homogeneous Dirichlet boundary conditions. To accomplish this, the problem is framed within an abstract setting, employing the -semigroup theory on time scales. Moreover, we apply a technique introduced by Bashirov et al. [1, 2], which enables us to avoid relying on fixed point theorems.
An Seir Model On Time Scales With Discrete Applications To Tuberculosis, E. Akın, G. Yeni, D. Konur, S. R. Işık, M. R. Işık
An Seir Model On Time Scales With Discrete Applications To Tuberculosis, E. Akın, G. Yeni, D. Konur, S. R. Işık, M. R. Işık
Mathematics and Statistics Faculty Research & Creative Works
In this paper, we propose a novel dynamical model on time scales consisting of new parameters to investigate the transmission dynamics of tuberculosis (TB), one of the deadliest infectious diseases worldwide, characterized by a long latency stage. The dynamical TB model, governed by the Susceptible–Exposed–Infected–Recovered (SEIR) framework within a unified form, yields a continuous model with a non-saturated incidence rate on the real numbers and discrete models with saturated incidence rates when different time domains are chosen. We analyze the stability of the equilibrium points of both the continuous TB model on the set of real numbers and the discrete …
Molecular Lung Imaging Following Exposure To Radiation Predicts Long-Term Survival In Rats, Anne V. Clough, Kathrina Mpala, Taheri Pardis, Laura Norwood Toro, Andreas M. Beyer, Tracy Gasperetti, Ming Zhao, Sarah Kerns, Heather A. Himburg, Said H. Audi
Molecular Lung Imaging Following Exposure To Radiation Predicts Long-Term Survival In Rats, Anne V. Clough, Kathrina Mpala, Taheri Pardis, Laura Norwood Toro, Andreas M. Beyer, Tracy Gasperetti, Ming Zhao, Sarah Kerns, Heather A. Himburg, Said H. Audi
Mathematical and Statistical Science Faculty Research and Publications
Delayed effects of acute radiation exposure (DEARE), including radiation pneumonitis (lung-DEARE), develop weeks to months after radiation exposure. Pathway-targeted biomarkers that capture early oxidative stress and cell death could improve risk stratification and provide objective measures of mitigator efficacy. The objective was to test whether molecular lung imaging predicts long-term survival and mitigator response after irradiation. Rats received 13.5 Gy leg-out partial-body irradiation with a subset treated with the radiation-injury mitigator lisinopril. Rats underwent lung imaging at weeks 2 and 4 post-irradiation with 99mTc-duramycin (cell death) and 99mTc-HMPAO (oxidative stress). Plasma mitochondrial damage-associated molecular patterns (mtDAMPs) were also …