Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (202)
- Medicine and Health Sciences (192)
- Computer Sciences (185)
- Bioinformatics (163)
- Biomedical Informatics (158)
-
- Social and Behavioral Sciences (113)
- Engineering (100)
- Artificial Intelligence and Robotics (96)
- Statistics and Probability (87)
- Medical Sciences (71)
- Medical Specialties (60)
- Public Affairs, Public Policy and Public Administration (44)
- Statistical Models (36)
- Science and Technology Policy (35)
- Business (32)
- Databases and Information Systems (31)
- Computer Engineering (30)
- Electrical and Computer Engineering (30)
- Environmental Sciences (28)
- Mathematics (28)
- Public Health (28)
- Applied Mathematics (25)
- Applied Statistics (25)
- Theory and Algorithms (24)
- Diseases (23)
- Oncology (22)
- Data Storage Systems (19)
- Earth Sciences (19)
- Institution
-
- The Texas Medical Center Library (156)
- Chinese Academy of Sciences (33)
- Old Dominion University (31)
- Universitas Negeri Malang (17)
- Southern Methodist University (16)
-
- CCT College Dublin (15)
- Purdue University (15)
- Chapman University (14)
- University of Central Florida (14)
- City University of New York (CUNY) (13)
- University of Arkansas, Fayetteville (12)
- University of Texas at Arlington (11)
- Clemson University (10)
- Case Western Reserve University (8)
- Minnesota State University, Mankato (8)
- Air Force Institute of Technology (7)
- Kennesaw State University (7)
- New Jersey Institute of Technology (7)
- West Virginia University (7)
- California Polytechnic State University, San Luis Obispo (6)
- Dartmouth College (6)
- Georgia Southern University (6)
- Utah State University (6)
- Virginia Commonwealth University (6)
- Claremont Colleges (5)
- Embry-Riddle Aeronautical University (5)
- Smith College (5)
- University of Texas Rio Grande Valley (5)
- Washington University in St. Louis (5)
- DePaul University (4)
- Keyword
-
- Humans (81)
- Machine Learning (35)
- Machine learning (32)
- Male (28)
- Female (26)
-
- Computer Science (18)
- Deep learning (18)
- Middle Aged (15)
- Animals (14)
- Adult (13)
- Artificial Intelligence (12)
- Artificial intelligence (12)
- Deep Learning (12)
- Electronic Health Records (12)
- Natural Language Processing (12)
- Aged (11)
- Data Science (10)
- Data science (10)
- Mice (10)
- Neoplasms (10)
- China (9)
- Neural Networks (8)
- COVID-19 (7)
- Adolescent (6)
- Data visualization (6)
- Genome-Wide Association Study (6)
- Healthcare (6)
- NLP (6)
- Prospective Studies (6)
- Sentiment Analysis (6)
- Publication
-
- Faculty, Staff and Student Publications (154)
- Bulletin of Chinese Academy of Sciences (Chinese Version) (33)
- Theses and Dissertations (18)
- Knowledge Engineering and Data Science (17)
- ICT (15)
-
- SMU Data Science Review (14)
- Data Science and Data Mining (12)
- Data Science Undergraduate Honors Theses (11)
- Dissertations, Theses, and Capstone Projects (10)
- Dissertations (9)
- Computer Science Faculty Publications (8)
- All Dissertations (7)
- All Graduate Theses, Dissertations, and Other Capstone Projects (7)
- Electronic Theses and Dissertations (7)
- Graduate Industrial Research Symposium (7)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (7)
- Computer Science and Engineering Dissertations - Archive (6)
- The Journal of Purdue Undergraduate Research (6)
- College of Graduate Studies: Theses & Dissertations (5)
- Computational and Data Sciences (PhD) Dissertations (5)
- Master's Theses (5)
- Statistical and Data Sciences: Faculty Publications (5)
- Electrical & Computer Engineering Faculty Publications (4)
- McKelvey School of Engineering Graduate Student Theses & Dissertations (4)
- SDSU Data Science Symposium (4)
- 2024 AI for Research Week (3)
- All Theses (3)
- CMC Senior Theses (3)
- Dartmouth College Master’s Theses (3)
- Electronic Theses, Projects, and Dissertations (3)
- Publication Type
- File Type
Articles 211 - 240 of 601
Full-Text Articles in Data Science
Baseball Decision-Making: Optimizing At-Bat Simulations, Varun Gopal, Krithika Kondakindi, Nibhrat Lohia, Morgan Williams
Baseball Decision-Making: Optimizing At-Bat Simulations, Varun Gopal, Krithika Kondakindi, Nibhrat Lohia, Morgan Williams
SMU Data Science Review
Pitch selection in baseball plays a crucial role, involving pitchers, catchers, and batters working together. This practice, dating back to early baseball, has seen teams try various methods to gain an advantage. This research aims to use reinforcement learning and pitch-by-pitch Statcast data to improve batting strategies. It also builds on previous statistical work (sabermetrics) to make better choices in pitch selection and plate discipline. The dataset used, including over 700,000 pitches for each full season and 200,000 pitches for the COVID-shortened 2020 season, encompasses a wealth of crucial metrics including pitch release point, velocity, and launch angle. This study …
Reevaluating Texas Energy Market Forecasts In The Wake Of Recent Extreme Weather Events, Robert A. Derner, Richard W. Butler Ii, Alexandria Neff, Adam R. Ruthford
Reevaluating Texas Energy Market Forecasts In The Wake Of Recent Extreme Weather Events, Robert A. Derner, Richard W. Butler Ii, Alexandria Neff, Adam R. Ruthford
SMU Data Science Review
This paper provides updated forecasts of energy demand in Texas and recognizes the impact of sustainable energy. It is important that the forecasts of the adoption of sustainable energy are reexamined after Winter Storm Uri crippled the Texas power grid and left many without power. This storm highlighted the issues the Texas power grid had and has continued to struggle with in supplying the state with energy. This paper will offer an overview of the relevant literature on the adoption of sustainable energy and relevant events that have occurred in the state of Texas that will give the reader the …
Multi-Class Emotion Classification With Xgboost Model Using Wearable Eeg Headband Data, James Khamthung, Nibhrat Lohia, Seement Srivastava
Multi-Class Emotion Classification With Xgboost Model Using Wearable Eeg Headband Data, James Khamthung, Nibhrat Lohia, Seement Srivastava
SMU Data Science Review
Electroencephalography (EEG) or brainwave signals serve as a valuable source for discerning human activities, thoughts, and emotions. This study explores the efficacy of EXtreme Gradient Boosting (XGBoost) models in sentiment classification using EEG signals, specifically those captured by the MUSE EEG headband. The MUSE device, equipped with four EEG electrodes (TP9, AF7, AF8, TP10), offers a cost-effective alternative to traditional EEG setups, which often utilize over 60 channels in laboratory-grade settings. Leveraging a dataset from previous MUSE research (Bird, J. et al., 2019), emotional states (positive, neutral, and negative) were observed in a male and a female participant, each for …
Building Effective Large Language Model Agents, Sydney Holder, Shreyash Taywade
Building Effective Large Language Model Agents, Sydney Holder, Shreyash Taywade
SMU Data Science Review
The advancement of large language models (LLMs) has significantly expanded the influence of artificial intelligence across various sectors. This paper explores building LLM agents to power applications and examines what is necessary to build an efficient and helpful AI assistant. The research investigates the core components necessary to create specialized agents, facilitate collaboration in problem-solving, and improve human task performance. The development and application of tools designed to augment the capabilities of LLM agents are also explored. The paper addresses the potential risks of the unknowns, such as hallucinations, which can compromise the success of agent-based solutions within LLM applications. …
Game Recommendation Analysis Using Steam Profiles And Reviews, Robert Blue, Luis Garcia, Jacob Turner
Game Recommendation Analysis Using Steam Profiles And Reviews, Robert Blue, Luis Garcia, Jacob Turner
SMU Data Science Review
Smaller game studios are at a disadvantage when it comes to getting their product noticed by users. This study aims to provide insights on how recommendation engines work so that these smaller studios can have their games noticed on Steam. Steam is one of the largest video game distribution services and they have a recommendation engine which promotes games to its user base. This study utilized user information such as number of games played, the type of games, and the hours played and created recommendation engines to identify the qualities in the game that are driving recommendations.
Leveraging Transformer Models For Genre Classification, Andreea C. Craus, Ben Berger, Yves Hughes, Hayley Horn
Leveraging Transformer Models For Genre Classification, Andreea C. Craus, Ben Berger, Yves Hughes, Hayley Horn
SMU Data Science Review
As the digital music landscape continues to expand, the need for effective methods to understand and contextualize the diverse genres of lyrical content becomes increasingly critical. This research focuses on the application of transformer models in the domain of music analysis, specifically in the task of lyric genre classification. By leveraging the advanced capabilities of transformer architectures, this project aims to capture intricate linguistic nuances within song lyrics, thereby enhancing the accuracy and efficiency of genre classification. The relevance of this project lies in its potential to contribute to the development of automated systems for music recommendation and genre-based playlist …
Detecting Drifts In Data Streams Using Kullback-Leibler (Kl) Divergence Measure For Data Engineering Applications, Jeomoan Francis Kurian, Mohamed Allali
Detecting Drifts In Data Streams Using Kullback-Leibler (Kl) Divergence Measure For Data Engineering Applications, Jeomoan Francis Kurian, Mohamed Allali
Engineering Faculty Articles and Research
The exponential growth of data coupled with the widespread application of artificial intelligence(AI) presents organizations with challenges in upholding data accuracy, especially within data engineering functions. While the Extraction, Transformation, and Loading process addresses error-free data ingestion, validating the content within data streams remains a challenge. Prompt detection and remediation of data issues are crucial, especially in automated analytical environments driven by AI. To address these issues, this study focuses on detecting drifts in data distributions and divergence within data fields processed from different sample populations. Using a hypothetical banking scenario, we illustrate the impact of data drift on automated …
Academic Search And Discovery Tools In The Age Of Ai And Large Language Models: An Overview Of The Space, Aaron Tay
2024 AI for Research Week
In the ever-evolving landscape of academic research, “AI tools” for literature search and synthesis are currently getting a lot of attention. These tools promise to ramp up productivity, enabling us to accomplish more in less time or absorb more knowledge without drowning in endless reading. With the sheer number of these systems increasing daily, it's natural to wonder: are they really worth our time and money? And if they are, how should we go about picking the right one from the multitude of options?
In this talk, I will share my views on how the space has developed over two …
Dynamic Hydrogel-Metal-Organic Framework System Promotes Bone Regeneration In Periodontitis Through Controlled Drug Delivery, Qipei Luo, Yuxin Yang, Chingchun Ho, Zongtai Li, Weicheng Chiu, Anqi Li, Yulin Dai, Weichang Li, Xinchun Zhang
Dynamic Hydrogel-Metal-Organic Framework System Promotes Bone Regeneration In Periodontitis Through Controlled Drug Delivery, Qipei Luo, Yuxin Yang, Chingchun Ho, Zongtai Li, Weicheng Chiu, Anqi Li, Yulin Dai, Weichang Li, Xinchun Zhang
Faculty, Staff and Student Publications
Periodontitis is a prevalent chronic inflammatory disease, which leads to gradual degradation of alveolar bone. The challenges persist in achieving effective alveolar bone repair due to the unique bacterial microenvironment's impact on immune responses. This study explores a novel approach utilizing Metal-Organic Frameworks (MOFs) (comprising magnesium and gallic acid) for promoting bone regeneration in periodontitis, which focuses on the physiological roles of magnesium ions in bone repair and gallic acid's antioxidant and immunomodulatory properties. However, the dynamic oral environment and irregular periodontal pockets pose challenges for sustained drug delivery. A smart responsive hydrogel system, integrating Carboxymethyl Chitosan (CMCS), Dextran (DEX) …
Context Aware Music Recommendation And Playlist Generation, Elias Mann
Context Aware Music Recommendation And Playlist Generation, Elias Mann
SMU Journal of Undergraduate Research
There are many reasons people listen to music, and the type of music is largely determined by what the listener may be doing while they listen. For example, one may listen to one type of music while commuting, another while exercising, and yet another while relaxing. Without access to the physiological state of the user, current music recommendation methods rely on collaborative filtering - recommending music based on what other similar users listen to - and content based filtering - recommending songs based on their similarities to songs the user already prefers. With the rise in popularity of smart devices …
A Pilot Acceptability Evaluation Of Mommind: A Digital Health Intervention For Peripartum Depression Prevention And Management Focused On Health Disparities, Alexandra Zingg, Amy Franklin, Angela Ross, Sahiti Myneni
A Pilot Acceptability Evaluation Of Mommind: A Digital Health Intervention For Peripartum Depression Prevention And Management Focused On Health Disparities, Alexandra Zingg, Amy Franklin, Angela Ross, Sahiti Myneni
Faculty, Staff and Student Publications
Health disparities cause significant strain on the wellbeing of individuals and society. In this study, we focus on the health disparities present in the condition of Peripartum Depression (PPD), a significant public health issue. While PPD can be managed through therapy and medication, many women do not receive adequate PPD treatment due to issues of social stigma and limited access to healthcare resources. Digital health technologies can offer practical tools for PPD management. However, current solutions do not integrate behavior theory and are rarely responsive to the transient information needs stemming from women's unique sociodemographic, clinical and psychosocial profiles. We …
Big Life-Science: Study Of Omics From Microscopic To Mesoscopic Scales, Jiarui Wu
Big Life-Science: Study Of Omics From Microscopic To Mesoscopic Scales, Jiarui Wu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The human genome project at the turn of the century opened a new era of life science research and formed various omics characterized by holistic high-throughput research. The initial omics research was mainly carried out at the molecular level, such as genomics, transcriptomics, proteomics, etc., showing a new paradigm of data-driven research. With the development of research technologies, the omics research has risen to the mesoscopic level, the representative is the “Human Cell Atlas” project launched in 2017. At present, researchers have been able to carry out omics research at the level of tissues, organs, and even individuals, and resulted …
Brain Science And Brain-Inspired Intelligence In Intelligent Era, Xu Zhang
Brain Science And Brain-Inspired Intelligence In Intelligent Era, Xu Zhang
Bulletin of Chinese Academy of Sciences (Chinese Version)
With intelligence technology as the core technology and intelligent computing power as the productive force, the intelligent era has once again pushed brain science to the forefront of world science and technology. Brain science is the science that studies the nature and rule of cognition and intelligence of human, animal, and machine. A comprehensive analysis of the structure and functional connection rule of the nervous system will eventually draw the functional connectivity map of the brain. In the past decade, neuroscience research has been committed to systematically analyzing the types of neurons and neural structural connections of the nervous system, …
Generalizing Parkinson’S Disease Detection Using Keystroke Dynamics: A Self-Supervised Approach, Shikha Tripathi, Alejandro Acien, Ashley A Holmes, Teresa Arroyo-Gallego, Luca Giancardo
Generalizing Parkinson’S Disease Detection Using Keystroke Dynamics: A Self-Supervised Approach, Shikha Tripathi, Alejandro Acien, Ashley A Holmes, Teresa Arroyo-Gallego, Luca Giancardo
Faculty, Staff and Student Publications
Objective: Passive monitoring of touchscreen interactions generates keystroke dynamic signals that can be used to detect and track neurological conditions such as Parkinson's disease (PD) and psychomotor impairment with minimal burden on the user. However, this typically requires datasets with clinically confirmed labels collected in standardized environments, which is challenging, especially for a large subject pool. This study validates the efficacy of a self-supervised learning method in reducing the reliance on labels and evaluates its generalizability.
Materials and methods: We propose a new type of self-supervised loss combining Barlow Twins loss, which attempts to create similar feature representations with reduced …
Advances In Data-Driven Life Sciences Research, Haiping Jiang, Chunchun Gao, Wenhao Liu, Yungui Yang, Xin Li
Advances In Data-Driven Life Sciences Research, Haiping Jiang, Chunchun Gao, Wenhao Liu, Yungui Yang, Xin Li
Bulletin of Chinese Academy of Sciences (Chinese Version)
The field of life sciences is rapidly evolving, driven by advancements in experimental techniques and vast biological big data which gradually arise and play an increasingly important role in life science research. First of all, biological big data has diversity and complexity, including genomic data, epigenomic data, proteomic data and other types. These data provide researchers with more comprehensive information and help reveal the laws behind life phenomena. Second, new data-driven developments and applications in life sciences cover many fields such as gene editing, precision medicine, drug development, etc., providing unprecedented possibilities for human health and quality of life. However, …
Technology Innovation Is The Key To Future Space Science Missions, Ji Wu
Technology Innovation Is The Key To Future Space Science Missions, Ji Wu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Space science is one of the important space activities of China together with space technology and space application. Although it is a space program aimed at scientific discovery and breakthrough, with the development of technology and the increasing number of achievements received in the past, space science missions require more and more technological innovation to achieve their goals. This study first reviews the development trend of space science missions since their birth, then analyzes the cultivation process of space science mission proposals with technological innovation and the responsibilities of the chief scientist leading such tasks, and finally analyzes and proposes …
Promoting Ecosystem Based Marine Management Through A Marine Ecological Classification And Zoning System, Wenhai Lu, Xiao Li, Meng Cui
Promoting Ecosystem Based Marine Management Through A Marine Ecological Classification And Zoning System, Wenhai Lu, Xiao Li, Meng Cui
Bulletin of Chinese Academy of Sciences (Chinese Version)
Ecosystem based ocean management is an important means of building marine ecological civilization. The current marine ecological classification and zoning in China comprehensively sorts out the types and natural geographical characteristics of marine ecosystems, divided the Chinese seas and adjacent waters into several levels of ecological spatial units according to different scales, effectively characterizes the geographical distribution features of marine biological communities and their habitats, and provides effective support for ecosystem based marine management. This study analyzed the practical significance of marine ecological classification and zoning. Based on a review of the development of marine ecological classification and zoning, this …
The Long-Term Effects Of Blood Urea Nitrogen Levels On Cardiovascular Disease And All-Cause Mortality In Diabetes: A Prospective Cohort Study, Hongfang Liu, Xiaoqin Xin, Jinghui Gan, Jungao Huang
The Long-Term Effects Of Blood Urea Nitrogen Levels On Cardiovascular Disease And All-Cause Mortality In Diabetes: A Prospective Cohort Study, Hongfang Liu, Xiaoqin Xin, Jinghui Gan, Jungao Huang
Faculty, Staff and Student Publications
BACKGROUND: The long-term effects of blood urea nitrogen(BUN) in patients with diabetes remain unknown. Current studies reporting the target BUN level in patients with diabetes are also limited. Hence, this prospective study aimed to explore the relationship of BUN with all-cause and cardiovascular mortalities in patients with diabetes.
METHODS: In total, 10,507 participants with diabetes from the National Health and Nutrition Examination Survey (1999-2018) were enrolled. The causes and numbers of deaths were determined based on the National Death Index mortality data from the date of NHANES interview until follow-up (December 31, 2019). Multivariate Cox proportional hazard regression models were …
Dual-Domain Clustering Of Spatiotemporal Infectious Disease Data, Samuel R. Thornton, Erin C.S. Acquesta, Patrick D. Finley, Mansoor A. Haider
Dual-Domain Clustering Of Spatiotemporal Infectious Disease Data, Samuel R. Thornton, Erin C.S. Acquesta, Patrick D. Finley, Mansoor A. Haider
Biology and Medicine Through Mathematics Conference
No abstract provided.
Towards Machine Proficiency With Semantic Underspecification, Zachary S. Gottesman
Towards Machine Proficiency With Semantic Underspecification, Zachary S. Gottesman
Dartmouth College Master’s Theses
Human natural language communication frequently relies on extra-linguistic information to fill in gaps in the linguistic signal left by semantic underspecification, or the omission of details that can be inferred from prior knowledge or other modalities. Underspecification is particularly common in conversations between acquaintances, since these interlocutors share context. Underspecification is a key and beneficial feature of natural language that improves efficiency, although it can cause communication to fail if it is not resolved correctly. For language models to communicate effectively and in a human-like fashion, they must learn how to recognize and utilize underspecified language. This thesis argues that …
The Classification Of Internet Memes Through Supervised And Unsupervised Machine Learning Algorithms, William H. Little
The Classification Of Internet Memes Through Supervised And Unsupervised Machine Learning Algorithms, William H. Little
Symposium of Student Scholars
Memes, those captivating internet phenomena, effortlessly deliver online entertainment. By leveraging time-series data from Google Trends, we can vividly illustrate and dissect the dynamic trends in meme popularity. Previous studies have discerned four distinct post-peak popularity patterns— "smoothly decaying," "spikey decaying," "leveling off," and "long-term growth"—and elegantly modeled these using ordinary differential equations.
This research introduces a programmatic approach that harnesses both supervised and unsupervised machine learning algorithms. The dataset, now expanded to over 2000 elements, becomes the canvas for exploration. The K-means algorithm identifies clusters, which then serve as labels for the supervised SVC algorithm. The overarching goal is …
Characteristics Based Factor Models - Comparison Of Estimation Procedures, Henri Ohl
Characteristics Based Factor Models - Comparison Of Estimation Procedures, Henri Ohl
McKelvey School of Engineering Graduate Student Theses & Dissertations
Understanding cross-sectional and time series variation of asset returns is fundamental in finance, particularly in asset pricing. This thesis explores the integration of factor theory with machine learning to deepen our comprehension of these dynamics. Characteristics based factor models offer a systematic framework for quantifying an asset's underlying risk-return structure, leveraging time-varying conditional information on model parameters carried by firm-specific characteristics. These models serve as valuable tools for discerning the driving components of an asset's expected excess return. Recent research established a novel methodology for consistent parameter estimation within this framework, only requiring a large cross-section but not a long …
Capturing Higher-Order Relationships Through Information Decomposition, Aobo Lyu
Capturing Higher-Order Relationships Through Information Decomposition, Aobo Lyu
McKelvey School of Engineering Graduate Student Theses & Dissertations
Mutual information between two random variables is a well-studied notion, whose understanding is fairly complete. Mutual information between one random variable and a pair of other random variables, however, is a far more involved notion. Specifically, Shannon's mutual information does not capture fine-grained interactions between those three variables, resulting in limited insights in complex systems. To capture these fine-grained higher-order interactions among variables, Williams and Beer proposed a framework called Partial Information Decomposition (PID) to decompose this mutual information to information atoms, called unique, redundant, and synergistic, and proposed several operational axioms that these atoms must satisfy. This conceptual …
An Examination Of Behavior Of Youtube Commenters, John E. Leonard
An Examination Of Behavior Of Youtube Commenters, John E. Leonard
Computer Science ETDs
YouTube comments are a unique form of social media, as viewers mainly interact with other viewers through comments sections, and cannot choose to interact with specific people. This lack of control over which comments are presented to them forces users to view spam.
Multiple general patterns of behavior were found in the dataset of YouTube comments. For example, most users posted just after a video’s publication. In addition, users tended to watch videos in the evening over the early morning.
A novel method was found for quantifying the likelihood of coordinated accounts being controlled by one person using time sharing. …
Online Temporal Data Mining And Learning: Pursuing Enhanced Efficiency And Robust Algorithms, Sheng Zhong
Online Temporal Data Mining And Learning: Pursuing Enhanced Efficiency And Robust Algorithms, Sheng Zhong
Computer Science ETDs
Time series data mining and learning serve as a cornerstone across various domains, including finance, healthcare, and science. Recent advancements in network and sensor technologies have ignited an increasing interest in real-time temporal data mining and learning techniques. Various tasks benefit from these techniques, such as environmental monitoring, event detection, anomaly identification, and forecasting. However, these techniques still face significant challenges in the online environment settings, encompassing aspects like efficiency, accuracy, robustness, and scarcity of labeled data. This dissertation presents four innovative solutions: FilCorr, DCT-MASS, FewSig, and BitLINK to overcome these challenges. We evaluate each method and showcase their practical …
Mitochondria Regulate Proliferation In Adult Cardiac Myocytes, Gregory B Waypa, Kimberly A Smith, Paul T Mungai, Vincent J Dudley, Kathryn A Helmin, Benjamin D Singer, Clara Bien Peek, Joseph Bass, Lauren Nelson, Sanjiv J Shah, Gaston Ofman, J Andrew Wasserstrom, William A Muller, Alexander V Misharin, G R Scott Budinger, Hiam Abdala-Valencia, Navdeep S Chandel, Danijela Dokic, Elizabeth Bartom, Shuang Zhang, Yuki Tatekoshi, Amir Mahmoodzadeh, Hossein Ardehali, Edward B Thorp, Paul T Schumacker
Mitochondria Regulate Proliferation In Adult Cardiac Myocytes, Gregory B Waypa, Kimberly A Smith, Paul T Mungai, Vincent J Dudley, Kathryn A Helmin, Benjamin D Singer, Clara Bien Peek, Joseph Bass, Lauren Nelson, Sanjiv J Shah, Gaston Ofman, J Andrew Wasserstrom, William A Muller, Alexander V Misharin, G R Scott Budinger, Hiam Abdala-Valencia, Navdeep S Chandel, Danijela Dokic, Elizabeth Bartom, Shuang Zhang, Yuki Tatekoshi, Amir Mahmoodzadeh, Hossein Ardehali, Edward B Thorp, Paul T Schumacker
Faculty, Staff and Student Publications
Newborn mammalian cardiomyocytes quickly transition from a fetal to an adult phenotype that utilizes mitochondrial oxidative phosphorylation but loses mitotic capacity. We tested whether forced reversal of adult cardiomyocytes back to a fetal glycolytic phenotype would restore proliferative capacity. We deleted Uqcrfs1 (mitochondrial Rieske iron-sulfur protein, RISP) in hearts of adult mice. As RISP protein decreased, heart mitochondrial function declined, and glucose utilization increased. Simultaneously, the hearts underwent hyperplastic remodeling during which cardiomyocyte number doubled without cellular hypertrophy. Cellular energy supply was preserved, AMPK activation was absent, and mTOR activation was evident. In ischemic hearts with RISP deletion, new cardiomyocytes …
How Financial Beliefs And Behaviors Influence The Financial Health Of Individuals Struggling With Opioid Use Disorder, James R Langabeer, Francine R Vega, Marylou Cardenas-Turanzas, A Sarah Cohen, Karima Lalani, Tiffany Champagne-Langabeer
How Financial Beliefs And Behaviors Influence The Financial Health Of Individuals Struggling With Opioid Use Disorder, James R Langabeer, Francine R Vega, Marylou Cardenas-Turanzas, A Sarah Cohen, Karima Lalani, Tiffany Champagne-Langabeer
Faculty, Staff and Student Publications
The surge in opioid use disorder (OUD) over the past decade escalated opioid overdoses to a leading cause of death in the United States. With adverse effects on cognition, risk-taking, and decision-making, OUD may negatively influence financial well-being. This study examined the financial health of individuals diagnosed with OUD by reviewing financial beliefs and financial behaviors. We evaluated quality of life, perceptions of financial condition during active use and recovery, and total debt. We distributed a 20-item survey to 150 individuals in an outpatient treatment program for OUD in a large metropolitan area, yielding a 56% response rate. The results …
High-Density Genetic Map Construction And Qtl Mapping Of A Zigzag-Shaped Stem Trait In Tea Plant (Camellia Sinensis), Dingding Liu, Yuanyuan Ye, Rongjin Tang, Yang Gong, Si Chen, Chenyu Zhang, Piao Mei, Jiedan Chen, Liang Chen, Chunlei Ma
High-Density Genetic Map Construction And Qtl Mapping Of A Zigzag-Shaped Stem Trait In Tea Plant (Camellia Sinensis), Dingding Liu, Yuanyuan Ye, Rongjin Tang, Yang Gong, Si Chen, Chenyu Zhang, Piao Mei, Jiedan Chen, Liang Chen, Chunlei Ma
Faculty, Staff and Student Publications
The highly unique zigzag-shaped stem phenotype in tea plants boasts significant ornamental value and is exceptionally rare. To investigate the genetic mechanism behind this trait, we developed BC1 artificial hybrid populations. Our genetic analysis revealed the zigzag-shaped trait as a qualitative trait. Utilizing whole-genome resequencing, we constructed a high-density genetic map from the BC1 population, incorporating 5,250 SNP markers across 15 linkage groups, covering 3,328.51 cM with an average marker interval distance of 0.68 cM. A quantitative trait locus (QTL) for the zigzag-shaped trait was identified on chromosome 4, within a 61.2 to 97.2 Mb range, accounting for a phenotypic …
A Nlp Approach To Automating The Generation Of Surveys For Market Research, Anav Chug
A Nlp Approach To Automating The Generation Of Surveys For Market Research, Anav Chug
Honors College Theses
Market Research is vital but includes activities that are often laborious and time consuming. Survey questionnaires are one possible output of the process and market researchers spend a lot of time manually developing questions for focus groups. The proposed research aims to develop a software prototype that utilizes Natural Language Processing (NLP) to automate the process of generating survey questions for market research. The software uses a pre-trained Open AI language model to generate multiple choice survey questions based on a given product prompt, send it to a targeted email list, and also provides a real-time analysis of the responses …
Evaluating Neuroimaging Modalities In The A/T/N Framework: Single And Combined Fdg-Pet And T1-Weighted Mri For Alzheimer’S Diagnosis, Peiwang Liu
McKelvey School of Engineering Graduate Student Theses & Dissertations
With the escalating prevalence of dementia, particularly Alzheimer's Disease (AD), the need for early and precise diagnostic techniques is rising. This study delves into the comparative efficacy of Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) and T1-weighted Magnetic Resonance Imaging (MRI) in diagnosing AD, where the integration of multimodal models is becoming a trend. Leveraging data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), we employed linear Support Vector Machines (SVM) to assess the diagnostic potential of these modalities, both individually and in combination, within the AD continuum. Our analysis, under the A/T/N framework's 'N' category, reveals that FDG-PET consistently outperforms T1w-MRI across …