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Full-Text Articles in Other Computer Sciences
Context Aware Privacy Preserving Clustering And Classification, Nirmal Thapa
Context Aware Privacy Preserving Clustering And Classification, Nirmal Thapa
Theses and Dissertations--Computer Science
Data are valuable assets to any organizations or individuals. Data are sources of useful information which is a big part of decision making. All sectors have potential to benefit from having information. Commerce, health, and research are some of the fields that have benefited from data. On the other hand, the availability of the data makes it easy for anyone to exploit the data, which in many cases are private confidential data. It is necessary to preserve the confidentiality of the data. We study two categories of privacy: Data Value Hiding and Data Pattern Hiding. Privacy is a huge concern …
A Novel Computational Framework For Transcriptome Analysis With Rna-Seq Data, Yin Hu
A Novel Computational Framework For Transcriptome Analysis With Rna-Seq Data, Yin Hu
Theses and Dissertations--Computer Science
The advance of high-throughput sequencing technologies and their application on mRNA transcriptome sequencing (RNA-seq) have enabled comprehensive and unbiased profiling of the landscape of transcription in a cell. In order to address the current limitation of analyzing accuracy and scalability in transcriptome analysis, a novel computational framework has been developed on large-scale RNA-seq datasets with no dependence on transcript annotations. Directly from raw reads, a probabilistic approach is first applied to infer the best transcript fragment alignments from paired-end reads. Empowered by the identification of alternative splicing modules, this framework then performs precise and efficient differential analysis at automatically detected …