Artificial Intelligence and Robotics Commons^™

Individualized Bayesian Inference Identifies Novel Genetic Variants For Parkinson's Disease, Jin Ren, Yasaman J. Soofi, Md Asad Rahman, Qing Lu, Jinling Liu

Engineering Management and Systems Engineering Faculty Research & Creative Works

Parkinson's disease (PD) is a complex neurodegenerative disorder with a significant genetic component. While genome-wide association studies (GWAS) have been instrumental in identifying genetic variants associated with PD, the reliance on large sample sizes and population-level analyses may overlook variants with lower minor allele frequencies or individual-specific relevance. Individualized Bayesian Inference (IBI) offers a promising method to complement GWAS by identifying and prioritizing candidate genetic markers at both the individual and patients-like-me subgroup levels. This study evaluates the application of IBI to PD genetics, using GWAS as a baseline for comparison. We analyzed genetic data from the Fox Insight online …

Evaluating Machine Learning Models On Classification Of Novel Cyber Attacks In The Healthcare Domain, Promise Ehimen

Dissertations, Theses, and Projects

The increasing adoption of the Internet of Medical Things (IoMT) has improved healthcare delivery through connected medical devices while simultaneously expanding the cybersecurity risks facing healthcare organizations. Although machine learning based intrusion detection systems have demonstrated high detection accuracy, their ability to respond reliably to previously unseen cyberattacks remains uncertain. This study investigated how a Neural Network model and a Logistic Regression model classified novel cyberattacks within the IoMT environment. The Neural Network and Logistic Regression models were both trained and tested using a subset of the CICIoMT2024 benchmark dataset. The Neural Network achieved 99.82% test accuracy and a 0.94 …

Multimodal Machine Learning For Soil Burn Severity Mapping Across California Wildfires, Sanjana Checker

Master's Theses

Accurate mapping of soil burn severity (SBS) is critical for post-fire watershed management, erosion risk assessment, and ecological recovery planning, yet traditional field-based approaches remain costly, time-intensive, and spatially limited. This thesis presents a machine learning pipeline for wall-to-wall SBS classification across California wildfires using multi-sensor satellite imagery, terrain derivatives, and bioclimatic covariates. Field-collected SBS observations (n = 2,180) from 52 wildfires occur- ring between 2013 and 2025, sourced from the U.S. Forest Service and CAL FIRE, were used to train and evaluate multiple classification architectures within a Google Earth Engine and Google Cloud-based prediction framework. After upsampling the unburned …

Developing A Comprehensive Resource Guide For Caregivers Within The Area Agency On Aging, Aiden R. Murphy

Public Health Capstone Projects

This project developed a new universal caregiver resource guide for caregivers within the Area Agency on Aging, in order to improve resource navigation and workflow efficiency. Resources were collected, verified, and organized into a new, streamlined guide via the ARIA chatbot, covering multiple needs. Caregiver resources were collected and verified by the capstone student and mentor, Michael Kroeker, and organized into a centralized knowledge base within the ARIA chatbot. A mixed methods evaluation was conducted utilizing a 5-point Likert scale with three quantitative questions and one open-ended qualitative question. The data was given to the SeniorLine staff, who wanted to …

Pyspqr: A Python Package For Density Estimation Using Deep Learning, Cameron Eddy, Reetam Majumder

Electrical Engineering and Computer Science Undergraduate Honors Theses

Splines are used for representing complex functions. In statistics, splines can be used for distributional shapes that are difficult to model by traditional parametric approaches. Ramsay (1) uses M-Spline bases to estimate continuous distributions. Semi-Parametric Quantile Regression (SPQR), developed by Xu and Reich (2), models conditional distributions where a neural network is used to estimate the basis function weights that depend on covariates. (3) implements a package for SPQR in R. We build on this by implementing a version of SPQR in Python with PyTorch. By using PyTorch, we can use more sophisticated deep learning architectures than those available in …

A General Weighting Theory For Ensemble Learning: Beyond Variance Reduction Via Spectral And Geometric Structure, Ernest Fokoue

Articles

Ensemble learning is traditionally justified as a variance-reduction strategy, explaining its strong performance for unstable predictors such as decision trees. This explanation, however, does not account for ensembles constructed from intrinsically stable estimators-including smoothing splines, kernel ridge regression, Gaussian process regression, and other regularized reproducing kernel Hilbert space (RKHS) methods whose variance is already tightly controlled by regularization and spectral shrinkage. This paper develops a general weighting theory for ensemble learning that moves beyond classical variance-reduction arguments. We formalize ensembles as linear operators acting on a hypothesis space and endow the space of weighting sequences with geometric and spectral constraints. …

Availability Model To Evaluate Ai Data Centers’ Role In Grid Stability, Troy Mcsimov, Trevor S. Kunz, Jeffrey Billo

SMU Data Science Review

The United States has made it clear; it is imperative that the US wins the global AI race. This paper focuses on one of the most challenging puzzle pieces surfaced at the POWER Data Center conference (San Antonio, Sept. 30.); for Electric Reliability Council of Texas (ERCOT) the limiting factor is not generation alone but the need to balance generation and load to preserve grid reliability.

The regulatory landscape fundamentally changed with the passage of Texas Senate Bill 6 in June 2025, which mandates new large loads must "contribute to the recovery of the interconnecting electric utility’s costs" (Texas Legislature, …

Using Ensemble Disagreement To Stabilize Conformal Prediction Under Distribution Shift, Patrick D. Murphy

Master's Theses

Semantic segmentation of eelgrass from drone imagery is crucial for coastal habitat monitoring, restoration, and management, as these habitats continue to see rapid changes due to climate change and human influence. However, the reliability of generalizing a deployed classification model relies on both high-accuracy segmentation as well as robust uncertainty quantification that holds up when conditions change over years or locations. Conformal prediction (CP) is a method that converts a classifier's output into prediction sets with a guaranteed average coverage level for in-distribution data. However, the “vanilla” conformal score can often under-cover in hard or out-of-distribution (OOD) regions under drift. …

Typeface: Machine-Viewing Gentrification On Storefront Imagery In Bedford-Stuyvesant, Brooklyn, Alexander Mcquilkin

Dissertations, Theses, and Capstone Projects

Gentrification—broadly, the replacement of a less powerful group by a more powerful one in an urban context—is oft-discussed in the popular press, but its definition is much-debated in the urban planning literature. Furthermore, academic treatments of displacement understandably focus on measurable yet fairly abstract indicators like changes in rent or income, whereas neighborhood change is often registered by residents on the ground using visual, but difficult-to-quantify markers like retail turnover. This project uses image recognition technology on a set of storefront photos to index the visual streetscape of a neighborhood, as well as to track changes to that portrait over …

Swimming In Uncertainty: Filling Data Gaps And Providing An Educational Platform For Beach Water Quality At Tybee Island, Georgia, Lukas Roberson

College of Graduate Studies: Theses & Dissertations

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Swimming in beaches water contaminated with high levels of bacteria can make you sick. Current monitoring at the public beaches on Tybee Island consists of weekly monitoring and enumeration of fecal indicator bacteria that takes 24 hours for results. If the number of bacteria exceed regulatory limits, a public health advisory is issued, and affected waters are retested until …

Challenges And Applications Of Fine-Grained Temporal Action Understanding: Modeling Temporal Granularity And Data Efficiency, Halil I. Helvaci

Theses and Dissertations--Electrical and Computer Engineering

Fine-grained Temporal Action Segmentation (TAS) has become a cornerstone of video understanding, offering dense frame-level predictions essential for clinical assessment, surgical skill evaluation, and human-computer interaction. While TAS methods have delivered strong results on coarse-grained benchmarks, two fundamental challenges persist: (1) global attention mechanisms dilute boundary information critical for subsecond precision, a phenomenon we term the temporal granularity bottleneck, and (2) dense frame-level annotation remains prohibitively expensive, with most datasets requiring exhaustive labeling of lengthy untrimmed videos. These challenges are particularly pronounced in medical domains, where sub-second primitives define clinical outcomes while expert annotation remains scarce. In this dissertation, we …

Algorithmic Trading In Idiosyncratic-Payoff Markets: A Multi-Agent System For On-Chain Prediction Contracts, Saif Aldeen A.K. Agha

CMC Senior Theses

This thesis documents the design, deployment, and forward-test evaluation of an evolutionary multi-agent algorithmic trading system on Polymarket, the largest decentralized prediction market. The system pairs a locally-hosted 72-billion-parameter language model with a gradient-boosted statistical filter and an evolutionary selection mechanism that maintains a population of approximately 500 autonomous trading agents. Each agent generates a probability estimate for an event, compares it to the prevailing market price, and trades the resulting disagreement.

The central empirical exercise estimates a panel regression of trade-level profit on the absolute disagreement between the agent's probability estimate and the market price, controlling for agent identity, …

Explainable Ai For Liver Transplant Survival Prediction: Integrating Immunological Mismatch Features, Sourab Shaik

Honors Projects

Liver Transplantations are crucial treatment for end-stage liver disease. However, a persistent deficit of donor organs necessitates maximizing the utility of each available graft to minimize failure rates. We evaluated whether donor–recipient molecular immunogenicity metrics - Electrostatic and Hydrophobic Mismatch Scores (HMS/EMS) and eplet-based counts - improve post–liver-transplant survival prediction. The analytic cohort comprised adult, first time, single-organ deceased-donor transplants drawn from Scientific Registry of Transplant Recipients; follow-up was truncated at five years, and the endpoint was all-cause graft failure (earliest of graft failure or death; otherwise, censored). HLA variables were derived via high- resolution conversion and molecular mismatch computations …

Bridging Machine Learning And Islamic Scholarship: A Study In Hadith Translation And Similarity Analysis, Asiyah R. Speight

Student Scholar Symposium Abstracts and Posters

Translation of Islamic religious texts poses unique challenges requiring both linguistic and theological expertise. This study explores the application of neural machine translation (NMT) models to Arabic-English hadith translation while analyzing semantic similarity patterns across different human translations. Using the complete Sahih Bukhari corpus (7,550 hadiths) as the primary dataset, we adopt a dual approach combining transfer learning and comprehensive neural network analysis to demonstrate the critical impact of corpus size on model performance.

First, we fine-tune a pre-trained MarianMT Arabic-English translation model on the full Sahih Bukhari corpus, comparing models trained on 40 hadiths versus 7,550 hadiths. Performance is …

Iso-Detr: A Novel Detection Transformer For Industrial Small Object Detection, Faisal Saeed, Anand Paul

School of Public Health Faculty Publications

Effectively detecting and assessing real-time structural and ecological parameters in contemporary manufacturing environments poses significant challenges, particularly in identifying minute objects within product images. The swift evolution of the industrial sector underscores the necessity for intelligent manufacturing environments to uphold stringent product quality standards. However, accelerating production processes at high speeds heightens the risk of defective product outcomes. This research addresses the challenges inherent in small object detection within industrial contexts, proposing an innovative detection transformer model tailored to modern manufacturing environments. The proposed model integrates a feature-enhanced multi-head self-attention block (FEMSA), merging cross-channel communication network and multiple multi-head self-attention …

Curvilinear Image Segmentation Using Multiscale Variational U-Net, Rebekah Fortes

LSU New Orleans Theses and Dissertations

Segmentation of curvilinear structures such as water contours, cracks in cement, and vascular networks in biomedical imaging, poses unique challenges due to extreme class imbalance, irregular morphology, low contrast against complex backgrounds, and the need to preserve global connectivity while detecting fine-scale details. We propose a Multiscale Variational U-Net (MSVU-Net) architecture designed specifically to address these challenges. The model integrates multiscale convolutional filters to capture both global context and local detail, while embedding a variational model in the bottleneck layer to enhance structural representation. To mitigate class imbalance and improve fidelity, the network optimizes a hybrid loss function that combines …

Benchmarking Dna Foundation Models For Genomic And Genetic Tasks, Haonan Feng, Lang Wu, Bingxin Zhao, Chad Huff, Jianjun Zhang, Jia Wu, Lifeng Lin, Peng Wei, Chong Wu

School of Medicine Faculty Publications

The rapid evolution of DNA foundation models promises to revolutionize genomics, yet comprehensive evaluations are lacking. Here, we present a comprehensive, unbiased benchmark of five models (DNABERT-2, Nucleotide Transformer V2, HyenaDNA, Caduceus-Ph, and GROVER) across diverse genomic and genetic tasks including sequence classification, gene expression prediction, variant effect quantification, and topologically associating domain (TAD) region recognition, using zero-shot embeddings. Our analysis reveals that mean token embedding consistently and significantly improves sequence classification performance, outperforming other pooling strategies. Model performance varies among tasks and datasets; while general purpose DNA foundation models showed competitive performance in pathogenic variant identification, they were less …

Heuristic Weight Initialization For Transfer Learning In Classification Problems, Musulmon Lolaev, Anand Paul, Jeonghong Kim

School of Public Health Faculty Publications

Transfer learning is the predominant method for adapting pre-trained models on another task to new domains while preserving their internal architectures and augmenting them with requisite layers in Deep Neural Network models. Training intricate pre-trained models on a sizable dataset requires significant resources to fine-tune hyperparameters carefully. Most existing initialization methods mainly focus on gradient flow-related problems, such as gradient vanishing or exploding, or other existing approaches that require extra models that do not consider our setting, which is more practical. To address these problems, we suggest employing gradient-free heuristic methods to initialize the weights of the final new-added fully …

Ibi-Dt: A Novel Approach Combining Individualized Bayesian Inference And Decision Tree For Identifying Cancer Drivers And Their Interactions, Md Asad Rahman, Gregory F. Cooper, Jinying Zhao, Xinghua Lu, Jinling Liu

Engineering Management and Systems Engineering Faculty Research & Creative Works

Cancer is mainly caused by a relatively small portion of somatic genome alterations (SGAs), called cancer drivers. Despite success in identifying a good number of cancer drivers, many more remain to be discovered to explain various cancers. Moreover, limited tools are available to identify potential interactions among cancer drivers for a better understanding of oncogenesis. To tackle these challenges, we have developed a novel approach called individualized Bayesian inference using a decision tree (IBI-DT). IBI-DT recognizes the genetic heterogeneity among cancer patients, where different individuals or patient subgroups of distinct genomic makeup may have different drivers. IBI-DT works by constructing …

Syntax-Enhanced Boundary-Aware Named Entity Recognition Model, Chuanming Yu, Bin Deng, Zhengang Zhang

Journal of Scientific Information Research

[Purpose/significance] This study addresses the issue of inadequate perception of entity boundaries in traditional character-level modeling-based named entity recognition models by integrating syntax information containing entity boundary features into the task using a multi-head graph attention network with dense connections. This integration enhances the effectiveness of named entity recognition.

[Method/process] This study proposes a Syntax-enhanced Boundary-aware Named Entity Recognition Model (SynBNER), which utilizes BERT for text semantic representation and integrates syntax information using a dense-connected graph attention network. This integration incorporates implicit entity boundary information from syntax information into word representations, thereby enhancing the model's entity boundary perception capability.

[Result/conclusion] …

A Comparative Study Of Neural Networks And Xgboost Models For Flight Time Prediction, Ioannis Paraschos, Taryn E. Trimble, Eshna Bhargava, Jake Klingler, Benjamin R. Nicolai

Beyond: Undergraduate Research Journal

Flight time prediction plays a crucial role in modern air travel, benefiting airlines and passengers alike. Accurate predictions enable airlines to optimize schedules, allocate resources effectively, and ensure passenger safety and satisfaction. In recent years, machine learning models, such as neural networks and XGBoost, have gained popularity for predicting flight times. This study aims to compare the performance of neural network and XGBoost models in predicting flight times, considering factors such as weather conditions, air traffic control, and aircraft performance. The results indicate that both models are effective, with XGBoost achieving slightly higher accuracy. However, neural networks offer advantages in …

Forecasting Influenza Rates Using Machine Learning: A Study Of Chatgpt's Predictive Accuracy, Sara Saleh

University Honors Theses

This study evaluates ChatGPT's ability to forecast influenza rates, such as the number of flu cases, hospitalizations, and death during peak season periods using CDC data, and comparing forecasts against actual results to calculate statistical accuracy and consistency. Influenza forecasting is essential for public health planning, but traditional methods may not always provide timely or accurate predictions. In this research study, ChatGPT was utilized to predict the influenza rates for the following week based on the previous week's data obtained from the FluView surveillance system. The predicted rates were compared to the actual influenza rates to assess the model's overall …

Topodino: Self-Supervised Topological Representation Learning For Neuronal Morphologies, Yasser Binbisher

Master's Theses

Neuronal cell types are categorized by transcriptomic identity, yet their morphological heterogeneity defies this classification. In response, researchers have adopted unsupervised graph representation learning as a tool to reveal morphological variation within single-class transcriptomic types. However, the complex geometry of neuronal morphology—especially long axons and dense dendrites—challenges graph neural networks, which struggle with message propagation across extended structures. To mitigate this, current approaches enforce sub-sampling on neuronal graphs and omit axons entirely, sacrificing critical biological features for computational efficiency. To overcome this trade-off, this thesis introduces TopoDINO, a self-supervised, topology-aware representation learning model designed to preserve the full hierarchical organization …

Property Testing Ai: An Efficient Frontier, Paul Sopher Lintilhac

Dartmouth College Ph.D Dissertations

In this dissertation, we take a step towards addressing the major problem of a lack of standardized and rigorous approaches to testing and evaluation of AI systems. Taking inspiration from both the fields of Property Testing and Property Based Testing (for programs), we develop a novel taxonomy of partially overlapping classes of properties of AI systems, including simple properties, compound properties, higher order properties, data relation properties, and architecture-utility properties. We argue that this taxonomy categorizes a diverse set of AI traits -- including accuracy, fairness, robustness, monotonicity, point-wise and global privacy properties, sensitivity, and more -- according to the …

Opening The Black Box With Regal: A Novel Explainable Ai Approach To Uncover Key Predictors In Search And Rescue Success, Brandon Hyunjun Kim

Master's Theses

The outcome of a search and rescue (SAR) operation is influenced by a complex, non-linear interplay among numerous factors, including geographic context, subject-specific characteristics, and environmental conditions. The high dimensionality and intricate dependencies among these variables pose significant challenges to traditional exploratory modeling approaches, limiting their ability to uncover meaningful patterns and relationships associated with mission success. This study introduces Rules Based Explanations for Generated neighborhoods Around Localized cases (REGAL), a novel adaptation of the Local Interpretable Model-agnostic Explanations (LIME) framework to explain deep multimodal neural networks and what key features it assesses to determine search and rescue success. REGAL …

Computer Vision In Soccer: Yolov11 Analytics Engine For Quantifying Game Strategy, Connor S. Maurer

Data Science Undergraduate Honors Theses

Single-shot object detection capabilities significantly reduce computational overhead for real-time computer vision in sports analytics at 60 FPS. YOLO11’s lightweight CNN gives promising accuracy while meeting the low-latency demand of dynamic soccer matches. As data-driven approaches take over the sport of soccer, efficient player tracking systems become critical for informing coach’s strategies. I prototype the ETL (Extract, Transform, Load) process of data collected from a single- shot detection program and evaluate its viability for estimating player fatigue. YOLO11 detects players, the ball, and other characteristics, with the output transformed by homography to estimate the positions in the real world. These …

Reinforcement Learning, Modeling Markets, And Professional Basketball Free Agency, Jacob Cohn

Computational and Data Sciences (PhD) Dissertations

This dissertation presents a reinforcement learning-based approach to modeling and optimizing decision-making in professional basketball free agency and related economic environments. A Markov Decision Process (MDP) framework is introduced to capture the strategic interactions of NBA teams bidding for free agents under budgetary and roster constraints. To address computational scalability challenges, a reinforcement learning (RL) environment is developed, leveraging Proximal Policy Optimization (PPO) to approximate optimal policies for team decision-making.

Empirical results demonstrate that the RL agent successfully learns strategic bidding behavior that aligns with dynamic programming benchmarks in simplified settings while scaling effectively to larger, intractable environments. The study …

Expressive And Interpretable User Engagement Prediction Using Multivariate Survival Processes, Akshay Aravamudan

Theses and Dissertations

The ability to characterize how information diffuses online is of paramount importance to stakeholders that are interested in tasks such as proposing solutions for mitigating and countering dis/misinformation, predicting user engagement of content in social media, planning marketing campaigns to roll-out products and planning dissemination of political campaign messaging among others. One such facet of learning the dynamics of information diffusion is the ability to predict user engagement or the popularity of a single piece of information as it spreads through an online medium. Existing works in this regard mainly either obfuscate user level information or utilize frameworks that are …

Leveraging Benford’S Law And Machine Learning For Financial Fraud Detection, Benjamin R. Fu

Cybersecurity Undergraduate Research Showcase

Financial fraud, particularly credit card fraud, continues to pose substantial challenges to financial institutions due to its increasing frequency and impact on consumer trust. While traditional rule-based methods have provided foundational defenses, their limitations in scalability and adaptability have accelerated the adoption of machine learning (ML) techniques. Concurrently, Benford’s Law—a statistical principle often used in forensic accounting—has demonstrated efficacy in detecting anomalies within naturally occurring numerical datasets. This study explores a hybrid fraud detection approach that integrates Benford’s Law with supervised machine learning algorithms, including Logistic Regression, Random Forest, and k-Nearest Neighbors. Using the publicly available European credit card fraud …

A Machine-Learning Tool-Supported Methodology For Nonprofit Donor Analysis, Corbin Weiss

Campus Research Month

We developed a machine-learning tool-supported methodology for modeling the nonprofit donor relationship. This approach was demonstrated in the case of a US-based nonprofit. Conclusions were drawn from this example and tool-support provided for use by other nonprofits.