Computer Sciences Commons^™

Machine Learning And Protein Engineering Approaches To Understanding Kinesin-5 Activity, Jason Eden Sanchez

Open Access Theses & Dissertations

Cancer is a term describing a collection of diseases that result in uncontrolled cell growth. Cancer has manifold etiologies and underlying cancers are rouge biochemical pathways involving many different proteins. In the current work, two approaches are used to enhance knowledge of kinesin-5, a potential cancer target involved in cell division. Kinesin-5 promotes cell division by cross-linking and separating microtubules in dividing cells. The first approach uses machine learning (ML) to identify small molecule inhibitors for kinesin-5. Though decades of research have uncovered classes of small-molecules which inhibit kinesin-5 in vitro and in vivo, no candidates have reached phase III …

Strengthening The Bonds Between Us: An Empirical Investigation Of Morale In Human-Ai Teams And The Socially Supportive Ai Teammates Who Empower It, Rohit Mallick

All Dissertations

This dissertation investigates how artificial intelligence (AI) can be designed to improve the collective emotion within a team. A team's collective emotion, or morale, describes how motivated, optimistic, and enthusiastic the group is in accomplishing its goals. We conducted four studies that compared different social support strategies that AI teammates can provide to the team. Study 1A found that AI teammates who communicate with emotions can better motivate human team members and promote awareness of team dynamics and environmental changes. Study 1B found that human teammates become more motivated and happier when their AI teammates express joy and are close …

Automated Solar Pv Analysis With Machine Learning And Computer Vision: Dataset And Methodology, Malachi Massey

Electrical Engineering and Computer Science Undergraduate Honors Theses

Solar power is a vital resource in a world being threatened with the ever-evolving impacts of climate change. A combination of new and developing technologies have allowed solar photovoltaic installation to increase at an exponential rate. With this rapid and unprecedented growth comes the task of maintaining tens of thousands of square miles of solar photovoltaic panels. Manually observing and testing solar PV panels for defects or obstructions is costly and time-consuming, distracting valuable resources from the continued installation of new units. This research aims to (i) firstly, introduce a novel dataset on solar PV obstruction, named De-Solar dataset; (ii) …

Improving Home Security Through User Centered Device Positioning, Lalith Nadipalli

Theses and Dissertations

In today’s world, where technology is advancing rapidly and security threats are becoming more complex, the need for effective home safety measures is more critical than ever. Homeowners are increasingly turning to a variety of smart devices, such as smoke detectors, carbon monoxide detectors, and security cameras, to protect their living spaces against potential dangers like burglary, fire, and environmental hazards. These devices offer essential protection, acting as both early warning systems and visual surveillance tools. However, their effectiveness largely hinges on how well they are placed within the home. Proper placement of these safety devices ensures that they provide …

Investigating Students’ Proficiency Across Statistical Software And Preferences Of Statistical Software Design, Sabrina White

Honors College Theses

This paper investigated students’ perceptions of their proficiency with statistical software applications and their preferences regarding software features. Results indicated that students’ statistical and coding experience, as well as the specific application used, did not significantly influence their self-perceived proficiency. This suggests that it may be more effective to focus on building student skills within a chosen application, rather than tailoring the application to match existing student capabilities. While students showed clear preferences for certain features, favoring clarity over depth, flexibility over safeguards, and built-in checks over unrestricted freedom, these preferences generally leaned toward balanced design rather than extremes. This …

Maximal Independent Set Algorithms Within Procedural Planar Maps: A Large-Scale Evaluation, Chaucer Ihrig

Honors College Theses

Analysis of a childhood game has led us to the problem of maximum independent sets in planar graphs. We wrote a graph creation utility using R to generate a random planar map and its dual graph. This utility then finds a graph’s maximal independent set using a variety of six algorithms. We investigate statistical connections between graph structure, colorability, and the maximal independent sets found using these algorithms over an incredibly large and procedurally generated dataset. We find one can always win the coloring game if the resultant graph is two-colorable. The algorithms perform statistically and practically significantly better on …

Exploring The Pedagogical Impact Of Software Development Live Streams: Informal Learning Opportunities For Software And Game Developers, Ella Kokinda

All Dissertations

Live streaming is an increasingly popular medium for throwing back the curtain on software development where streamers and viewers share their knowledge and experiences. Popular platforms like Twitch and YouTube enable developers to stream live coding sessions where people around the world can engage in real-time collaboration, feedback, knowledge sharing, and skill development. This work investigates the pedagogical implications and learning opportunities present in software and game development live streaming while focusing on the role of streaming as a learning environment and collaborative community. We begin by exploring summer camps as an informal learning opportunity for STEM education, highlighting the …

Cybersecurity's Pr Problem: The Education Gap Fueling Mfa Aversion, Tyler M. Stafford, Catherine Dwyer

Honors College Theses

Through surveying individuals with no professional experience in cybersecurity, this study examines the relationship between awareness and education surrounding security controls and end users’ willingness to adopt them. The findings reveal a strong link between understanding the effectiveness of these controls and user comfort, indicating that as end users’ understanding increases, so does their willingness to use the controls. Working in both identity and access management (IAM) and human risk management, I observed what appeared to be a connection between security education and positive attitudes toward security more broadly, but found limited research statistically linking the two. This study’s findings …

Toward Robust Semantic Segmentation In Levee Infrastructure Monitoring: Enhancing Accuracy With High-Fidelity Synthetic Data And Ensemble Learning, Padam Jung Thapa

LSU New Orleans Theses and Dissertations

Abstract: Levees serve as critical flood protection structures, but failures due to inadequate maintenance and extreme water pressures have led to devastating events such as Hurricane Katrina. Manual inspections are slow, labor-intensive, and prone to human error, necessitating the development of automated solutions. This study proposes an AI-driven framework for levee inspection utilizing deep learning-based semantic segmentation to detect rutting and enhance the identification of sand boils. To address dataset limitations, high-fidelity synthetic images are generated using DreamBooth for fine-tuning, while ControlNet adds structural constraints to enhance realism and consistency. A semi-automatic convex hull annotation technique enhances labeling efficiency, and …

Animal Burrow Detection In Levee Systems Using Res-Net 34, Christopher D. Moore

LSU New Orleans Theses and Dissertations

Animal burrow detection is a time-consuming and costly task for levee inspectors. Annual budgets run up to approximately $16 million per state. The inspectors typically will have to travel to the inspection sites using government-assigned transportation. Depending on the distance to the site, it may take minutes or hours to arrive before any productive inspections occur. Once at the site, the inspectors were subject to human error, overgrown foliage, severe weather, or prohibitive landscaping that would make any human inspection impossible. Also, animal burrows could be small enough or overgrown, so the human inspector misses the problem areas. We aimed …

Optimizing The Peter Kiewit Institute Course Schedule Using Answer Set Programming, Joshua R. Gryzen

Theses/Capstones/Creative Projects

This project introduces a program that automates the process of minimizing conflict between classes that students are likely to take simultaneously at the Peter Kiewit Institute at the University of Nebraska Omaha using Answer Set Programming. The main objectives of this project are to encode the specifics of a schedule regulation for courses pertinent to computer science majors, identify critical conflicts between the courses in a given schedule, and propose an assignment of timeslots. More specifically, a scheduled section is assigned a new timeslot, which is a combination of days, start time, and end time, from the list of timeslots …

Phoneme Recognition For Pronunciation Improvement, Matthew Heywood

Theses/Capstones/Creative Projects

This project aims to improve English pronunciation by investigating speech errors and developing a tool to provide precise feedback. The study focuses on creating a new pronunciation tool that offers localized feedback, identifies specific errors, and suggests corrective measures. By addressing the shortcomings of current methods, this research seeks to enhance pronunciation refinement.

Utilizing cutting-edge technology, the tool leverages speech-to-phoneme AI models and modified lazy string matching algorithms to compare the user's spoken input with the intended pronunciation. This allows for a detailed analysis of discrepancies, providing users actionable insights into their phonetic errors. The speech-to-phoneme AI models mark a …

Comparative Analysis Of Classical And Machine Learning Pathfinding Approaches, Miguel Gapud

Honors Theses

Pathfinding is an essential task for any autonomous robot. Graph-based classical pathfinding algorithms and machine learning approaches have both been used for this end, but they are often not compared against each other. An implementation of end-to-end (E2E) pathfinding using Proximal Policy Optimization (PPO) and an Alexnet architecture is compared against an implementation of Hybrid A*. A digital twin in Unity3D is used as the testing environment with the Clearpath Dingo as the pathfinding robot. In machine learning, the robot is controlled using PPO through ROS-Noetic with a camera as its sensor. Hybrid A* and its controls are implemented directly …

Key-Based Authentication Scheme For Evtol Drones Using Chebyshev Chaotic Maps, Eduardo A. Hernandez Escobar

Master's Theses

The development of electric Vertical Take-Off and Landing (eVTOL) drones signifies a substantial advancement in urban air mobility, ready to transform transportation models in densely populated regions. These advanced drones, distinguished by their capacity to function in limited spaces and their minimized environmental impact, are set to transform individual, shipping, emergency services, and public safety activities. Nonetheless, like any transformational technology, the implementation of eVTOL systems presents many challenges, especially in the realm of cybersecurity. Adding many devices and entities to an eVTOL network increases the risk of privacy and security attacks. This paper proposes a key-based authentication scheme that …

Real-Time Anomaly Detection In Ot Networks Using Gru-Based Autoencoders, Grant Austin Wilkins

Graduate Theses and Dissertations

Operational Technology (OT) networks, particularly those used in critical infrastructure, face increasing cyber threats that target network-level protocols and behaviors. While most anomaly detection research for OT systems has traditionally relied on sensor data, this thesis explores the viability of detecting malicious activity directly from network telemetry. We propose a sequence-to-sequence autoencoder model based on Gated Recurrent Units (GRUs) with multilevel attention, trained to reconstruct normal patterns of packet-level communication extracted from raw PCAP data. The developed feature engineering pipeline integrates general networking attributes such as IP and MAC addresses, ports, and transport protocols with OT-specific protocol information from Modbus …

A Robust Rf Fingerprinting Approach Using Physics-Informed Neural Networks, Jozef Dusenka

Graduate Theses and Dissertations

Radio frequency (RF) fingerprints, caused by unique imperfections in communication hardware, offer a promising solution for zero-trust security. However, existing RF fingerprinting techniques, which aim to extract these signatures from transmitters to uniquely identify devices, often struggle with robustness in the face of temporal and spatial variations in real-world, time-varying wireless environments. For example, a neural network trained on RF signals collected on Day 1 can experience a significant performance drop when tested with data from Day 2.

To address this challenge, we propose a novel, robust RF fingerprinting method based on Physics-Informed Neural Networks (PINNs). Rather than training the …

Adversarial Machine Learning: Methods For Attacks And Defenses, Minh Hao Van

Graduate Theses and Dissertations

With the rapid development of machine learning in real-world applications, enhancing security plays an important role. Adversarial machine learning focuses on understanding malicious actions from attackers and developing defensive techniques against such threats when deploying machine learning systems. An attack can occur in different scenarios, such as poisoning attacks during the training stage and evasion attacks during the testing stage. Although extensive research has explored defense strategies to deal with these harmful attacks, there is a need for further research into areas such as how to counteract malicious attacks with healthy noise or how to train an adaptive defense against …

A Hierarchical Soft Computational Model For Optimizing Agricultural Uavs: Recruiting Neutrosophic Theory And Tree Soft Sets, Mona Mohamed, Nurhan Alaa, Bilal Arain, Karam M. Sallam

Neutrosophic Systems with Applications

Precision agriculture is being transformed by Unmanned Aerial Vehicles (UAVs), which make it possible for yield optimization, targeted spraying, and sophisticated crop monitoring. With an emphasis on their operational capabilities, economic feasibility, and environmental implications, this research explores the revolutionary potential of UAV technology in contemporary farming systems. Practically speaking, the procedure of opting UAVs for agricultural applications is complicated by several competing aspects, inherent uncertainties, and differing stakeholder agendas. This paper suggests a new hybrid decision framework that combines Tree Soft Sets (TrSS), Neutrosophic theory, and Multi-Criteria Decision-Making (MCDM) to methodically handle these issues. Hence, the robust hybrid model …

A Comprehensive Performance Comparison Of Machine Learning And Federated Learning For Intrusion Detection In Vehicular Ad-Hoc Networks Using Can-Bus Data, Tim Leonhardt

Honors Theses

Federated Learning (FL) is a Machine Learning (ML) approach that decentralizes training across distributed devices, eliminating the need to centralize data. Unlike traditional ML, where models are trained on aggregated data, FL sends a global model to multiple nodes for local training, with updated parameters transmitted back to the server for aggregation. This process preserves data privacy, making FL ideal for sensitive applications like cybersecurity. However, FL introduces challenges such as data heterogeneity, communication overhead, and difficulties in achieving model convergence, which can impact performance.

This study investigates a fundamental assumption in ML and FL research: that the superior performance …

Quasipseudometric Value Functions With Dense Rewards, Khadichabonu Valieva

Honors Theses

Goal-conditioned reinforcement learning (GCRL) serves as an extension of reinforce- ment learning (RL) that focuses on goals that can be adjusted, making it useful for many applications, especially in complex robotics tasks. Recent research has established that the optimal value function of GCRL, denoted as Q∗(s, a, g), has a quasipseudometric structure. This finding has led to the development of targeted neural architectures that respect such a structure. However, prior analyses have predominantly focused on sparse reward settings, which are known to increase challenges related to sample complexity. In this work, I with the guidance of my advisor show that …

Cache-Augmented Generation In Rag Pipelines: Fast And Memory-Efficient Approach To Multi-Agent Knowledge Query Systems, Yaju Gopal Shrestha

Honors Theses

This thesis presents an implementation and evaluation of Cache-Augmented Generation (CAG) for knowledge query systems, building upon the approach introduced by Chan et al. (2024). Traditional Retrieval-Augmented Generation (RAG) systems (Lewis et al., 2020) face challenges including high latency, excessive memory usage, and complex infrastructure requirements. By implementing a cache-augmented architecture that preloads relevant knowledge and eliminates real-time retrieval, our approach significantly improves response time while reducing resource requirements. The research demonstrates the effectiveness of CAG through a comprehensive implementation for The University of Southern Mississippi's chatbot system, achieving a 49.02% improvement in response time compared to traditional RAG approaches. …

What References Are Chatgpt, Gemini, Copilot, And Perplexity Providing For Consumer Health Questions?, Scott Johnson, Catherine Johnson, Ivan Portillo

Library Presentations, Posters, and Audiovisual Materials

Background

With the growing popularity of generative artificial intelligence (AI) models such as ChatGPT, consumers may turn to these tools to easily seek health information. To our knowledge, no study has analyzed the references provided by multiple models for consumer health questions.

Objective

We aimed to analyze the references provided by ChatGPT, Gemini, Copilot, and Perplexity for consumer health questions in order to determine the most frequently appearing references.

Methods

AI generative models ChatGPT 4.0, Google Gemini, Microsoft Copilot, and Perplexity were each asked 30 consumer health questions and prompted to provide the corresponding references. The references were recorded.

The …

A Machine Learning Framework For Packet Anomaly Detection In Smartgrid Substation Networks, Sowmya Bandari

School of Computing: Dissertations, Theses, and Student Research

The increasing reliance on Smart Grid Substation Networks for efficient electricity distribution has amplified cybersecurity vulnerabilities, particularly within Supervisory Control and Data Acquisition (SCADA) systems. The IEC 60870-5-104 (IEC-104) protocol, widely adopted for communication between Remote Terminal Units (RTUs) and Human-Machine Interfaces (HMIs), lacks inherent encryption and authentication mechanisms, rendering it susceptible to sophisticated cyberattacks. Threats such as False Data Injection Attacks (FDIAs), command injection, covert attacks and replay attacks pose significant risks by manipulating grid control signals, potentially leading to undetected operational disruptions, cascading failures, or system-wide instability. Conventional signature-based Intrusion Detection Systems (IDS) often fail to identify zero-day …

Simulating Chill: Exploring The Cognitive And Therapeutic Potential Of Cold Vr Environments, Jessica Turner, Piper Hutson, James Hutson

Faculty Scholarship

This study investigates the cognitive and therapeutic potential of immersive virtual reality (VR) environments designed to simulate cold conditions. Through the engagement of participants through multisensory stimuli—including vivid visual representations of the Athabasca Glacier, auditory effects of icy winds, and corresponding haptic feedback—the research evaluates neurological and physiological responses associated with attention, emotional regulation, and stress modulation. Participants experienced virtual scenarios featuring icy winds and snow, activating specific neurological pathways involving the occipital lobe, primary visual cortex, superior colliculus, and insula, thus reinforcing sensory integration. Through predictive coding, the anterior insula and hypothalamus were engaged, prompting thermoregulatory simulations and subconscious …

1785 Parisian Salon Project: New Methods And Practical Innovations In Digital Heritage Reconstruction, James Hutson, Charles O'Brien, Wesley Wolfe, Kayla Kraff, Trent Olsen

Faculty Scholarship

The 1785 Salon Unreal Engine Reconstruction Project represents a significant advance in digital heritage and immersive art historical research by combining generative AI-based asset creation, modular user experience (UX) design, and historically informed workflows. During the Spring 2025 phase, the project achieved major milestones, including the successful development of a replicable pipeline for transforming 2D reference images into period-accurate 3D sculpture models using generative AI and digital sculpting tools. Simultaneously, a robust and adaptable Inspection System was engineered within Unreal Engine, offering granular interaction controls, bilingual (English/French) content integration, dynamic metadata display, and enhanced accessibility. These innovations collectively enabled historically …

Predicting Cardiac Resynchronization Therapy Response: Development And Validation Of A Single Photon Emission Computed Tomography-Based Nomogram, Zhongwei Jiang, Zhongqiang Zhao, Zhuo He, Qiushi Chen, Ju Bu, Chunxiang Li, Dianfu Li, Chang Cui, Weihua Zhou, Huiyuan Qin, Cheng Wang

Michigan Tech Publications

Background: Cardiac resynchronization therapy (CRT) is an effective treatment for patients with drug-refractory heart failure. However, more than thirty percent of patients do not benefit from CRT. This study aimed to develop and validate a novel model based on single photon emission computed tomography (SPECT) phase analysis features to predict CRT response. Methods: We identified 163 CRT patients who received gated resting SPECT myocardial perfusion imaging (MPI) between 2010 and 2020 at The First Affiliated Hospital of Nanjing Medical University. All variables were first processed by univariate logistic regression, and those with a P value < 0.05 were retained. The selected variables were subsequently used in the least absolute shrinkage and selection operator (LASSO) regression to construct a predictive model, which was then represented as a nomogram. Nomogram performance was assessed via receiver operating characteristic (ROC) curves, calibration curves, and decision curve analyses (DCAs). Internal validation was performed by bootstrapping with 1,000 replicates. Results: Of the 163 patients, 93 (57.1%) responded to CRT during follow-up. Responders had a wider QRS complex duration (QRSd) (164.80 vs. 154.51 ms, P=0.003), fewer premature ventricular contractions (PVCs) (1,392.98 vs. 2,283.60, P=0.003), lower prevalence of non-sustained ventricular tachycardia (NS-VT) (45.2% vs. 77.1%, P< 0.001), and better cardiac function [based on N-terminal pro-B-type natriuretic peptide (NT-proBNP), New York Heart Association (NYHA), and left ventricle (LV) parameters] compared to non-responders. Univariate logistic regression revealed 14 variables significantly associated with CRT response (all P< 0.05). The area under the ROC curve (AUC) value for the nomogram was 0.845 [95% confidence interval (CI): 0.785–0.906; sensitivity: 0.771; specificity: 0.849]. Internal validation yielded a mean AUC of 0.814 (95% CI: 0.777–0.836). The calibration curve demonstrated strong consistency between the predicted and observed outcomes. DCA revealed that the nomogram consistently provides a net benefit over the baseline, demonstrating its high practical value in clinical decision-making. A web-based dynamic nomogram (https:// jzw20000624.shinyapps.io/CRTpredictionmodel/) was developed for clinical application. Conclusions: We developed and validated a SPECT-based prediction model for predicting CRT response, which can assist clinicians in optimizing CRT candidacy preoperatively. Pacing at the latest contraction and relaxation segments, while avoiding scarred regions and optimizing preoperative status, is anticipated to improve CRT response.

Comparing Spatial Interfaces Of The Tower Of London Task, Paean Luby

Honors Theses

Executive functioning involves key mental skills like self-control and problem-solving, which are often impaired by brain injuries. The Tower of London (TOL) task is a problem set commonly used to assess planning, but both traditional and digital versions can lack consistency, and, in the case of digital versions, realism and physical engagement. Research shows that 3D tasks, such as a 3D version of the Tower of Hanoi, engage the brain in distinct and meaningful ways, likely due to increased spatial involvement. By merging immersive 3D environments with the consistency of digital tools, virtual reality (VR) has the potential to enhance …

Privacy-Aware Ai-Based Agricultural Monitoring Using Internet Of Drones, Md Benozir Hossain

Honors Theses

Artificial Intelligence (AI) has become a vital tool for agricultural farming. AI-based image processing models utilizing different machine learning (ML) algorithms and deep learning (DL) offer advanced functionalities in disease detection, yield estimation, land use, etc. This thesis examines AI-driven techniques utilizing Convolutional Neural Networks (CNN) with the addition of Federated Learning (FL) to analyze satellite and drone images for agricultural insights, especially in detecting Cotton diseases. The AI models improve agricultural farming in many ways, such as using data to make critical decisions, reducing labor costs, pest infestations, etc. Moreover, these models allow farmers to minimize yield losses by …

Effects Of Reflective Journaling And Nudges On Academic Motivation And Engagement, Lakshmi Satya Sai Veda Mahita Uppuluri

Theses and Dissertations

This study investigates the effects of reflective journaling and motivational nudges on academic motivation and engagement among college students. Grounded in Self- Determination Theory (SDT), the research examines how different interventions influence intrinsic motivation, and academic behaviors such as class attendance, participation, and preparation. The study employed a between-group experimental design with three conditions: a control group, a journaling group, and a journaling group that also received daily motivational nudges. Results showed that students in the journaling groups—particularly those who received nudges—experienced a significant increase in academic motivation. While changes in academic engagement were not significant, the effect size suggested …

Expressive And Interpretable User Engagement Prediction Using Multivariate Survival Processes, Akshay Aravamudan

Theses and Dissertations

The ability to characterize how information diffuses online is of paramount importance to stakeholders that are interested in tasks such as proposing solutions for mitigating and countering dis/misinformation, predicting user engagement of content in social media, planning marketing campaigns to roll-out products and planning dissemination of political campaign messaging among others. One such facet of learning the dynamics of information diffusion is the ability to predict user engagement or the popularity of a single piece of information as it spreads through an online medium. Existing works in this regard mainly either obfuscate user level information or utilize frameworks that are …