Computer Sciences Commons^™

Deepsec: A Deep Learning Framework For Secreted Protein Discovery In Human Body Fluids, Dan Shao, Lan Huang, Yan Wang, Kai He, Xueteng Cui, Yao Wang, Qin Ma, Juan Cui

School of Computing: Faculty Publications

Motivation: Human proteins that are secreted into different body fluids from various cells and tissues can be promising disease indicators. Modern proteomics research empowered by both qualitative and quantitative profiling techniques has made great progress in protein discovery in various human fluids. However, due to the large number of proteins and diverse modifications present in the fluids, as well as the existing technical limits of major proteomics platforms (e.g. mass spectrometry), large discrepancies are often generated from different experimental studies. As a result, a comprehensive proteomics landscape across major human fluids are not well determined.

Results: To bridge …

Power-Over-Tether Unmanned Aerial System Leveraged For Trajectory Influenced Atmospheric Sensing, Daniel Rico

School of Computing: Dissertations, Theses, and Student Research

The use of unmanned aerial systems (UASs) in agriculture has risen in the past decade and is helping to modernize agriculture. UASs collect and elucidate data previously difficult to obtain and are used to help increase agricultural efficiency and production. Typical commercial off-the-shelf (COTS) UASs are limited by small payloads and short flight times. Such limits inhibit their ability to provide abundant data at multiple spatiotemporal scales. In this thesis, we describe the design and construction of the tethered aircraft unmanned system (TAUS), which is a novel power-over-tether UAS configured for long-term, high throughput atmospheric monitoring with an array of …

A Real-World, Hybrid Event Sequence Generation Framework For Android Apps, Jun Sun

School of Computing: Dissertations, Theses, and Student Research

Generating meaningful inputs for Android apps is still a challenging issue that needs more research. Past research efforts have shown that random test generation is still an effective means to exercise User-Interface (UI) events to achieve high code coverage. At the same time, heuristic search approaches can effectively reach specified code targets. Our investigation shows that these approaches alone are insufficient to generate inputs that can exercise specific code locations in complex Android applications.

This thesis introduces a hybrid approach that combines two different input generation techniques--heuristic search based on genetic algorithm and random instigation of UI events, to reach …

Using Contextual Bandits To Improve Traffic Performance In Edge Network, Aziza Al Zadjali

School of Computing: Dissertations, Theses, and Student Research

Edge computing network is a great candidate to reduce latency and enhance performance of the Internet. The flexibility afforded by Edge computing to handle data creates exciting range of possibilities. However, Edge servers have some limitations since Edge computing process and analyze partial sets of information. It is challenging to allocate computing and network resources rationally to satisfy the requirement of mobile devices under uncertain wireless network, and meet the constraints of datacenter servers too. To combat these issues, this dissertation proposes smart multi armed bandit algorithms that decide the appropriate connection setup for multiple network access technologies on the …

Aerial Flight Paths For Communication, Alisha Bevins

School of Computing: Dissertations, Theses, and Student Research

This body of work presents an iterative process of refinement to understand naive perception of communication using the motion of an unmanned aerial vehicle (UAV). This includes what people believe the UAV is trying to communicate, and how they expect to respond through physical action or emotional response. Previous work in this area sought to communicate without clear definitions of the states attempting to be conveyed. In an attempt to present more concrete states and better understand specific motion perception, this work goes through multiple iterations of state elicitation and label assignment. The lessons learned in this work will be …

Facility Location Games With Ordinal Preferences, Hau Chan, Minming Li, Chenhao Wang

School of Computing: Faculty Publications

We consider a new setting of facility location games with ordinal preferences. In such a setting, we have a set of agents and a set of facilities. Each agent is located on a line and has an ordinal preference over the facilities. Our goal is to design strategyproof mechanisms that elicit truthful information (preferences and/or locations) from the agents and locate the facilities to minimize both maximum and total cost objectives as well as to maximize both minimum and total utility objectives. For the four possible objectives, we consider the 2-facility settings in which only preferences are private, or locations …

Economically Optimal Nitrogen Side-Dressing Based On Vegetation Indices From Satellite Images Through On-Farm Experiments, Qianqian Du

Department of Agricultural Economics: Dissertations, Theses, and Student Research

Optimal N fertilizer rates for corn (Zea mays L.) vary substantially within and among fields, and by corn growth stages. Improving N side-dressing management can improve fertilizer use efficiency, farmers’ profitability, and the sustainability of crop production. The objective of this study is to introduce a framework along with a methodology that can find the site-specific economically optimal N rates (EONRs) within one field for a particular growing season. An on-farm experiment was conducted in the 2019 corn growing season. A base N rate was applied uniformly on the field. NDRE images from the Sentinel-2 satellite were observed during …

Fire Suppression And Ignition With Unmanned Aerial Vehicles, Carrick Detweiler, Sebastian Elbaum, James Higgins, Christian Laney, Craig Allen, Dirac L. Twidwell Jr, Evan Michale Beachly

School of Computing: Faculty Publications

An unmanned aerial vehicle (UAV) can be configured for fire suppression and ignition. In some examples, the UAV includes an aerial propulsion system, an ignition system, and a control system. The ignition system includes a container of delayed-ignition balls and a dropper configured by virtue of one or more motors to actuate and drop the delayed-ignition balls. The control system is configured to cause the UAV to fly to a site of a prescribed burn and, while flying over the site of the prescribed burn, actuate one or more of the delayed-ignition balls. After actuating the one or more delayed-ignition …

The R Journal (June 2021) 13(1): Complete Issue, The R Foundation

The R Journal

Editorial, Dianne Cook

Contributed Research Articles

SEEDCCA: An Integrated R-Package for Canonical Correlation Analysis and Partial Least Squares, Bo-Young Kim, Yunju Im, and Jae Keun Yoo

npcure: An R Package for Nonparametric Inference in Mixture Cure Models, Ana López-Cheda, M. Amalia Jácome, and Ignacio López-de-Ullibarri

A Method for Deriving Information from Running R Code, Mark P. J. van der Loo

JMcmprsk: An R Package for Joint Modelling of Longitudinal and Survival Data with Competing Risks, Hong Wang, Ning Li, Shanpeng Li, and Gang Li

Wide-to-tall Data Reshaping Using Regular Expressions and the nc Package, Toby Dylan Hocking

Linear Regression with …

Analyzing Dependence Between Point Processes In Time Using Indtestpp, Ana C. Cebrián, Jesús Asín

The R Journal

The need to analyze the dependence between two or more point processes in time appears in many modeling problems related to the occurrence of events, such as the occurrence of climate events at different spatial locations or synchrony detection in spike train analysis. The package IndTestPP provides a general framework for all the steps in this type of analysis, and one of its main features is the implementation of three families of tests to study independence given the intensities of the processes, which are not only useful to assess independence but also to identify factors causing dependence. The package also …

Distr6: R6 Object-Oriented Probability Distributions Interface In R, Raphael Sonabend, Franz J. Király

The R Journal

distr6 is an object-oriented (OO) probability distributions interface leveraging the extensibility and scalability of R6 and the speed and efficiency of Rcpp. Over 50 probability distributions are currently implemented in the package with ‘core’ methods, including density, distribution, and generating functions, and more ‘exotic’ ones, including hazards and distribution function anti-derivatives. In addition to simple distributions, distr6 supports compositions such as truncation, mixtures, and product distributions. This paper presents the core functionality of the package and demonstrates examples for key use-cases. In addition, this paper provides a critical review of the object-oriented programming paradigms in R and describes some …

Krippendorffsalpha: An R Package For Measuring Agreement Using Krippendorff's Alpha Coefficient, John Hughes

The R Journal

R package krippendorffsalpha provides tools for measuring agreement using Krippendorff’s α coefficient, a well-known nonparametric measure of agreement (also called inter-rater reliability and various other names). This article first develops Krippendorff’s α in a natural way and situates α among statistical procedures. Then, the usage of package krippendorffsalpha is illustrated via analyses of two datasets, the latter of which was collected during an imaging study of hip cartilage. The package permits users to apply the α methodology using built-in distance functions for the nominal, ordinal, interval, or ratio levels of measurement. User-defined distance functions are also supported. The fitting function …

The R Package Smicd: Statistical Methods For Interval-Censored Data, Paul Walter

The R Journal

The package allows the use of two new statistical methods for the analysis of intervalcensored data: 1) direct estimation/prediction of statistical indicators and 2) linear (mixed) regression analysis. Direct estimation of statistical indicators, for instance, poverty and inequality indicators, is facilitated by a non parametric kernel density algorithm. The algorithm is able to account for weights in the estimation of statistical indicators. The standard errors of the statistical indicators are estimated with a non parametric bootstrap. Furthermore, the package offers statistical methods for the estimation of linear and linear mixed regression models with an interval-censored dependent variable, particularly random slope …

Finding Optimal Normalizing Transformations Via Bestnormalize, Ryan A. Peterson

The R Journal

The bestNormalize R package was designed to help users find a transformation that can effectively normalize a vector regardless of its actual distribution. Each of the many normalization techniques that have been developed has its own strengths and weaknesses, and deciding which to use until data are fully observed is difficult or impossible. This package facilitates choosing between a range of possible transformations and will automatically return the best one, i.e., the one that makes data look the most normal. To evaluate and compare the normalization efficacy across a suite of possible transformations, we developed a statistic based on a …

Robustness In Network (Robin): An R Package For Comparison And Validation Of Communities, Valeria Policastro, Dario Righelli, Annamaria Carissimo, Luisa Cutillo, Italia De Feis

The R Journal

In network analysis, many community detection algorithms have been developed. However, their implementation leaves unaddressed the question of the statistical validation of the results. Here, we present robin (ROBustness In Network), an R package to assess the robustness of the community structure of a network found by one or more methods to give indications about their reliability. The procedure initially detects if the community structure found by a set of algorithms is statistically significant and then compares two selected detection algorithms on the same graph to choose the one that better fits the network of interest. We demonstrate the use …

Indexnumber: An R Package For Measuring The Evolution Of Magnitudes, Alejandro Saavedra-Nieves, Paula Saavedra-Nieves

The R Journal

Index numbers are descriptive statistical measures useful in economic settings for comparing simple and complex magnitudes registered, usually in two time periods. Although this theory has a large history, it still plays an important role in modern today’s societies where big amounts of economic data are available and need to be analyzed. After a detailed revision on classical index numbers in literature, this paper is focused on the description of the R package IndexNumber with strong capabilities for calculating them. Two of the four real data sets contained in this library are used for illustrating the determination of the index …

Pdynmc: A Package For Estimating Linear Dynamic Panel Data Models Based On Nonlinear Moment Conditions, Markus Fritsch, Andrew Adrian Yu Pua, Joachim Schnurbus

The R Journal

This paper introduces pdynmc, an R package that provides users sufficient flexibility and precise control over the estimation and inference in linear dynamic panel data models. The package primarily allows for the inclusion of nonlinear moment conditions and the use of iterated GMM; additionally, visualizations for data structure and estimation results are provided. The current implementation reflects recent developments in literature, uses sensible argument defaults, and aligns commercial and noncommercial estimation commands. Since the understanding of the model assumptions is vital for setting up plausible estimation routines, we provide a broad introduction of linear dynamic panel data models directed towards …

Benchmarking R Packages For Calculation Of Persistent Homology, Eashwar V. Somasundaram, Shael E. Brown, Adam Litzler, Jacob G. Scott, Raoul R. Wadhwa

The R Journal

Several persistent homology software libraries have been implemented in R. Specifically, the Dionysus, GUDHI, and Ripser libraries have been wrapped by the TDA and TDAstats CRAN packages. These software represent powerful analysis tools that are computationally expensive and, to our knowledge, have not been formally benchmarked. Here, we analyze runtime and memory growth for the 2 R packages and the 3 underlying libraries. We find that datasets with less than 3 dimensions can be evaluated with persistent homology fastest by the GUDHI library in the TDA package. For higher-dimensional datasets, the Ripser library in the TDAstats package is the fastest. …

Unidimensional And Multidimensional Methods For Recurrence Quantification Analysis With Crqa, Moreno I. Coco, Dan Mønster, Giuseppe Leonardi, Rick Dale, Sebastian Wallot

The R Journal

Recurrence quantification analysis is a widely used method for characterizing patterns in time series. This article presents a comprehensive survey for conducting a wide range of recurrence-based analyses to quantify the dynamical structure of single and multivariate time series and capture coupling properties underlying leader-follower relationships. The basics of recurrence quantification analysis (RQA) and all its variants are formally introduced step-by-step from the simplest auto-recurrence to the most advanced multivariate case. Importantly, we show how such RQA methods can be deployed under a single computational framework in R using a substantially renewed version of our crqa 2.0 package. This package …

The Bdpar Package: Big Data Pipelining Architecture For R, Miguel Ferreiro-Díaz, Tomás R. Cotos-Yáñez, José R. Méndez, David Ruano-Ordás

The R Journal

In the last years, big data has become a useful paradigm for taking advantage of multiple sources to find relevant knowledge in real domains (such as the design of personalized marketing campaigns or helping to palliate the effects of several fatal diseases). Big data programming tools and methods have evolved over time from a MapReduce to a pipeline-based archetype. Concretely the use of pipelining schemes has become the most reliable way of processing and analyzing large amounts of data. To this end, this work introduces bdpar, a new highly customizable pipeline-based framework (using the OOP paradigm provided by R6 …

Exprior: An R Package For The Formulation Of Ex-Situ Priors, Falk Heße, Karina Cucchi, Nura Kawa, Yoram Rubin

The R Journal

The exPrior package implements a procedure for formulating informative priors of geostatistical properties for a target field site, called ex-situ priors and introduced in Cucchi et al. (2019). The procedure uses a Bayesian hierarchical model to assimilate multiple types of data coming from multiple sites considered as similar to the target site. This prior summarizes the information contained in the data in the form of a probability density function that can be used to better inform further geostatistical investigations at the site. The formulation of the prior uses ex-situ data, where the data set can either be gathered by the …

Linear Regression With Stationary Errors: The R Package Slm, Emmanuel Caron, Jérôme Dedecker, Bertrand Michel

The R Journal

This paper introduces the R package slm, which stands for Stationary Linear Models. The package contains a set of statistical procedures for linear regression in the general context where the error process is strictly stationary with a short memory. We work in the setting of Hannan (1973), who proved the asymptotic normality of the (normalized) least squares estimators (LSE) under very mild conditions on the error process. We propose different ways to estimate the asymptotic covariance matrix of the LSE and then to correct the type I error rates of the usual tests on the parameters (as well as confidence …

A Method For Deriving Information From Running R Code, Mark P. J. Van Der Loo

The R Journal

It is often useful to tap information from a running R script. Obvious use cases include monitoring the consumption of resources (time, memory) and logging. Perhaps less obvious cases include tracking changes in R objects or collecting the output of unit tests. In this paper, we demonstrate an approach that abstracts the collection and processing of such secondary information from the running R script. Our approach is based on a combination of three elements. The first element is to build a customized way to evaluate code. The second is labeled local masking and it involves temporarily masking a user-facing function …

Npcure: An R Package For Nonparametric Inference In Mixture Cure Models, Ana López-Cheda, M Amalia Jácome, Ignacio López-De-Ullibarri

The R Journal

Mixture cure models have been widely used to analyze survival data with a cure fraction. They assume that a subgroup of the individuals under study will never experience the event (cured subjects). So, the goal is twofold: to study both the cure probability and the failure time of the uncured individuals through a proper survival function (latency). The R package npcure implements a completely nonparametric approach for estimating these functions in mixture cure models, considering right-censored survival times. Nonparametric estimators for the cure probability and the latency as functions of a covariate are provided. Bootstrap bandwidth selectors for the estimators …

Seedcca: An Integrated R-Package For Canonical Correlation Analysis And Partial Least Squares, Bo-Young Kim, Yunju Im, Jae Keun Yoo

The R Journal

Canonical correlation analysis (CCA) has a long history as an explanatory statistical method in high-dimensional data analysis and has been successfully applied in many scientific fields such as chemometrics, pattern recognition, genomic sequence analysis, and so on. The so-called seedCCA is a newly developed R package that implements not only the standard and seeded CCA but also partial least squares. The package enables us to fit CCA to large-p and small-n data. The paper provides a complete guide. Also, the seeded CCA application results are compared with the regularized CCA in the existing R package. It is believed that the …

Conference Report Of Why R? Turkey 2021, Mustafa Cavus, Olgun Aydin, Ozan Evkaya, Ozancan Ozdemir, Deniz Bezer, Ugur Dar

The R Journal

The Why R? Turkey 2021 as a three-day online conference was organized to bring together researchers and professionals from Turkey on April 16-17-18, 2021. We hereby aimed to promote the R community in Turkey by bringing R users with different backgrounds such as genetics, sociology, finance, economy, bio-statistics. There were 8 thematic sessions and 18 invited speakers. In this article, it is aimed to describe the preparation phase, technical details, and the impact of the conference on audience.

News From The Forwards Taskforce, Heather Turner

The R Journal

Forwards is an R Foundation taskforce working to widen the participation of underrepresented groups in the R project and in related activities, such as the useR! conference. This report rounds up activities of the taskforce during the first half of 2021.

Changes On Cran, Kurt Hornik, Uwe Ligges, Achim Zeileis

The R Journal

In the past 6 months, 1290 new packages were added to the CRAN package repository. 116 packages were unarchived and 467 were archived. The following shows the growth of the number of active packages in the CRAN package repository

Regularized Transformation Models: The Tramnet Package, Lucas Kook, Torsten Hothorn

The R Journal

The tramnet package implements regularized linear transformation models by combining the flexible class of transformation models from tram with constrained convex optimization implemented in CVXR. Regularized transformation models unify many existing and novel regularized regression models under one theoretical and computational framework. Regularization strategies implemented for transformation models in tramnet include the Lasso, ridge regression, and the elastic net and follow the parameterization in glmnet. Several functionalities for optimizing the hyperparameters, including model-based optimization based on the mlrMBO package, are implemented. A multitude of S3 methods is deployed for visualization, handling, and simulation purposes. This work aims at illustrating all …

The Hbv.Ianigla Hydrological Model, Ezequiel Toum, Mariano H. Masiokas, Ricardo Villalba, Pierre Pitte, Lucas Ruiz

The R Journal

Over the past 40 years, the HBV (Hydrologiska Byråns Vattenbalansavdelning) hydrological model has been one of the most used worldwide due to its robustness, simplicity, and reliable results. Despite these advantages, the available versions impose some limitations for research studies in mountain watersheds dominated by ice-snow melt runoff (i.e., no glacier module, a limited number of elevation bands, among other constraints). Here we present HBV.IANIGLA, a tool for hydroclimatic studies in regions with steep topography and/or cryospheric processes which provides a modular and extended implementation of the HBV model as an R package. To our knowledge, this is the first …