Open Access. Powered by Scholars. Published by Universities.®

Computer Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 601 - 630 of 1803

Full-Text Articles in Computer Sciences

A New Method Using Deep Transfer Learning On Ecg To Predict The Response To Cardiac Resynchronization Therapy, Zhuo He, Hongjin Si, Xinwei Zhang, Qing-Hui Chen, Jiangang Zou, Weihua Zhou Jun 2023

A New Method Using Deep Transfer Learning On Ecg To Predict The Response To Cardiac Resynchronization Therapy, Zhuo He, Hongjin Si, Xinwei Zhang, Qing-Hui Chen, Jiangang Zou, Weihua Zhou

Michigan Tech Publications

Background: Cardiac resynchronization therapy (CRT) has emerged as an effective treatment for heart failure patients with electrical dyssynchrony. However, accurately predicting which patients will respond to CRT remains a challenge. This study explores the application of deep transfer learning techniques to train a predictive model for CRT response. Methods: In this study, the short-time Fourier transform (STFT) technique was employed to transform ECG signals into two-dimensional images. A transfer learning approach was then applied on the MIT-BIT ECG database to pre-train a convolutional neural network (CNN) model. The model was fine-tuned to extract relevant features from the ECG images, and …


Cybersecurity: Stochastic Intensity Function And Monitoring Indicators, Hackers Demographics, Statistical Analysis And Treatment Of Ovarian Cancer, Ranju Karki Jun 2023

Cybersecurity: Stochastic Intensity Function And Monitoring Indicators, Hackers Demographics, Statistical Analysis And Treatment Of Ovarian Cancer, Ranju Karki

USF Tampa Graduate Theses and Dissertations

One of the major tasks in the present day-era is securing computer systems against unauthorized access. Every year we lost millions of dollars because of cyber attacks and thousands of people suffer economically and psychologically. Rapid development in the field of information technology increases the challenges to the Information technology personnel working on protecting against cyber attacks. In cyber security, vulnerabilities and hackers play a major role. Researchers are putting in enormous efforts to develop methods and models to control vulnerabilities and psychological behavior and motivation of hackers. Our study defines two important aspects of the computer operating system concerning …


Patient Engagement In A Multimodal Digital Phenotyping Study Of Opioid Use Disorder, Cynthia I. Campbell, Ching-Hua Chen, Sara R. Adams, Asma Asyyed, Ninad R. Athale, Monique B. Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C. Jacobson, Heather K. Jones, David Kotz, Chantal A. Lambert-Harris, Zhiguo Li, Bethany Mcleman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Christopher Zegers, Lisa A. Marsch Jun 2023

Patient Engagement In A Multimodal Digital Phenotyping Study Of Opioid Use Disorder, Cynthia I. Campbell, Ching-Hua Chen, Sara R. Adams, Asma Asyyed, Ninad R. Athale, Monique B. Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C. Jacobson, Heather K. Jones, David Kotz, Chantal A. Lambert-Harris, Zhiguo Li, Bethany Mcleman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Christopher Zegers, Lisa A. Marsch

Dartmouth Scholarship

Background: Multiple digital data sources can capture moment-to-moment information to advance a robust understanding of opioid use disorder (OUD) behavior, ultimately creating a digital phenotype for each patient. This information can lead to individualized interventions to improve treatment for OUD.

Objective: The aim is to examine patient engagement with multiple digital phenotyping methods among patients receiving buprenorphine medication for OUD.

Methods: The study enrolled 65 patients receiving buprenorphine for OUD between June 2020 and January 2021 from 4 addiction medicine programs in an integrated health care delivery system in Northern California. Ecological momentary assessment (EMA), sensor data, and social media …


A Proposed Fair Approach For Disseminating Geospatial Information System Maps, P. Travis Thompson, Sweta Ojha, Christian D. Powell, Kelly G. Pennell, Hunter N. B. Moseley Jun 2023

A Proposed Fair Approach For Disseminating Geospatial Information System Maps, P. Travis Thompson, Sweta Ojha, Christian D. Powell, Kelly G. Pennell, Hunter N. B. Moseley

Markey Cancer Center Faculty Publications

We present a draft Minimum Information about Geospatial Information System (MIaGIS) standard for facilitating public deposition of geospatial information system (GIS) datasets that follows the FaIR (Findable, accessible, Interoperable and Reusable) principles. the draft MIaGIS standard includes a deposition directory structure and a minimum javascript object notation (JSON) metadata formatted file that is designed to capture critical metadata describing GIS layers and maps as well as their sources of data and methods of generation. the associated miagis Python package facilitates the creation of this MIAGIS metadata file and directly supports metadata extraction from both Esri JSON and GEOJSON GIS data …


Identifying And Sharing Per-And Polyfluoroalkyl Substances Hot-Spot Areas And Exposures In Drinking Water, Sweta Ojha, P. Travis Thompson, Christian D. Powell, Hunter N. B. Moseley, Kelly G. Pennell Jun 2023

Identifying And Sharing Per-And Polyfluoroalkyl Substances Hot-Spot Areas And Exposures In Drinking Water, Sweta Ojha, P. Travis Thompson, Christian D. Powell, Hunter N. B. Moseley, Kelly G. Pennell

Markey Cancer Center Faculty Publications

Exposure to per- and polyfluoroalkyl substances (PFAS) in drinking water is widely recognized as a public health concern. Decision-makers who are responsible for managing PFAS drinking water risks lack the tools to acquire the information they need. In response to this need, we provide a detailed description of a Kentucky dataset that allows decision-makers to visualize potential hot-spot areas and evaluate drinking water systems that may be susceptible to PFAS contamination. The dataset includes information extracted from publicly available sources to create five different maps in ArcGIS Online and highlights potential sources of PFAS contamination in the environment in relation …


Artificial Intelligence Cad Tools In Trauma Imaging: A Scoping Review From The American Society Of Emergency Radiology (Aser) Ai/Ml Expert Panel, David Dreizin, Pedro V Staziaki, Garvit D Khatri, Nicholas M Beckmann, Zhaoyong Feng, Yuanyuan Liang, Zachary S Delproposto, Maximiliano Klug, J Stephen Spann, Nathan Sarkar, Yunting Fu Jun 2023

Artificial Intelligence Cad Tools In Trauma Imaging: A Scoping Review From The American Society Of Emergency Radiology (Aser) Ai/Ml Expert Panel, David Dreizin, Pedro V Staziaki, Garvit D Khatri, Nicholas M Beckmann, Zhaoyong Feng, Yuanyuan Liang, Zachary S Delproposto, Maximiliano Klug, J Stephen Spann, Nathan Sarkar, Yunting Fu

Faculty, Staff and Student Publications

BACKGROUND: AI/ML CAD tools can potentially improve outcomes in the high-stakes, high-volume model of trauma radiology. No prior scoping review has been undertaken to comprehensively assess tools in this subspecialty.

PURPOSE: To map the evolution and current state of trauma radiology CAD tools along key dimensions of technology readiness.

METHODS: Following a search of databases, abstract screening, and full-text document review, CAD tool maturity was charted using elements of data curation, performance validation, outcomes research, explainability, user acceptance, and funding patterns. Descriptive statistics were used to illustrate key trends.

RESULTS: A total of 4052 records were screened, and 233 full-text …


Lessons Learned From The Hospital To Home Community Care Program In Singapore And The Supporting Ai Multiple Readmissions Prediction Model, John Abisheganaden, Kheng Hock Lee, Lian Leng Low, Eugene Shum, Han Leong Goh, Christine Gia Lee Ang, Adny An Ta Wee, Steven M. Miller Jun 2023

Lessons Learned From The Hospital To Home Community Care Program In Singapore And The Supporting Ai Multiple Readmissions Prediction Model, John Abisheganaden, Kheng Hock Lee, Lian Leng Low, Eugene Shum, Han Leong Goh, Christine Gia Lee Ang, Adny An Ta Wee, Steven M. Miller

Research Collection School Of Computing and Information Systems

In a prior practice and policy article published in Healthcare Science, we introduced the deployed application of an artificial intelligence (AI) model to predict longer-term inpatient readmissions to guide community care interventions for patients with complex conditions in the context of Singapore's Hospital to Home (H2H) program that has been operating since 2017. In this follow on practice and policy article, we further elaborate on Singapore's H2H program and care model, and its supporting AI model for multiple readmission prediction, in the following ways: (1) by providing updates on the AI and supporting information systems, (2) by reporting on customer …


Tracing The Twenty-Year Evolution Of Developing Ai For Eye Screening In Singapore: A Master Chronology Of Sidrp, Selena+ And Eyris, Steven M. Miller Jun 2023

Tracing The Twenty-Year Evolution Of Developing Ai For Eye Screening In Singapore: A Master Chronology Of Sidrp, Selena+ And Eyris, Steven M. Miller

Research Collection School Of Computing and Information Systems

This working paper is entirely comprised of a timeline table that begins in 2002 and runs through mid-2023. Across these two decades, this timeline traces the evolutionary development of the following:

  • The early Singapore R&D efforts to apply software-based image analysis algorithms and methods to analyse eye retina images for diabetic retinopathy and other eye diseases. This was based on a collaboration between the Singapore Eye Research Institute (SERI) and its parent organization, the Singapore National Eye Centre (SNEC), with faculty from the School of Computing at National University of Singapore.
  • The establishment and operation of the Singapore Integrated Diabetic …


Connecting Linguistic Expressions And Pain Relief Through Transformer Model Construction And Analysis, Sarah M. Chacko May 2023

Connecting Linguistic Expressions And Pain Relief Through Transformer Model Construction And Analysis, Sarah M. Chacko

Computer Science Senior Theses

Chronic pain is a widespread problem that significantly impacts quality of life. Overprescription and abuse of pain medication continues to be a major public health issue and can further burden patients due to a fragmented health care system. Previous research has suggested a possible psychological basis to pain and the potential for safer, non-pharmacological alternatives for pain relief. This project leverages language models to study chronic pain development and relief through psychological treatments, which will be assessed through responses to post-treatment interviews. A transformer-based natural language processing model is employed to identify connections between language expressions and pain on a …


Rapid Assessment Of Fish Freshness For Multiple Supply-Chain Nodes Using Multi-Mode Spectroscopy And Fusion-Based Artificial Intelligence, Hossein Kashani Zadeh, Mike Hardy, Mitchell Sueker, Yicong Li, Angelis Tzouchas, Nicholas Mackinnon, Gregory Bearman, Simon A Haughey, Alireza Akhbardeh, Insuck Baek, Chansong Hwang, Jianwei Qin, Amanda M Tabb, Rosalee S Hellberg, Shereen Ismail, Hassan Reza, Fartash Vasefi, Moon Kim, Kouhyar Tavakolian, Christopher T Elliott May 2023

Rapid Assessment Of Fish Freshness For Multiple Supply-Chain Nodes Using Multi-Mode Spectroscopy And Fusion-Based Artificial Intelligence, Hossein Kashani Zadeh, Mike Hardy, Mitchell Sueker, Yicong Li, Angelis Tzouchas, Nicholas Mackinnon, Gregory Bearman, Simon A Haughey, Alireza Akhbardeh, Insuck Baek, Chansong Hwang, Jianwei Qin, Amanda M Tabb, Rosalee S Hellberg, Shereen Ismail, Hassan Reza, Fartash Vasefi, Moon Kim, Kouhyar Tavakolian, Christopher T Elliott

Faculty, Staff and Student Publications

This study is directed towards developing a fast, non-destructive, and easy-to-use handheld multimode spectroscopic system for fish quality assessment. We apply data fusion of visible near infra-red (VIS-NIR) and short wave infra-red (SWIR) reflectance and fluorescence (FL) spectroscopy data features to classify fish from fresh to spoiled condition. Farmed Atlantic and wild coho and chinook salmon and sablefish fillets were measured. Three hundred measurement points on each of four fillets were taken every two days over 14 days for a total of 8400 measurements for each spectral mode. Multiple machine learning techniques including principal component analysis, self-organized maps, linear and …


Algorithmic Bias: Causes And Effects On Marginalized Communities, Katrina M. Baha May 2023

Algorithmic Bias: Causes And Effects On Marginalized Communities, Katrina M. Baha

Undergraduate Honors Theses

Individuals from marginalized backgrounds face different healthcare outcomes due to algorithmic bias in the technological healthcare industry. Algorithmic biases, which are the biases that arise from the set of steps used to solve or analyze a problem, are evident when people from marginalized communities use healthcare technology. For example, many pulse oximeters, which are the medical devices used to measure oxygen saturation in the blood, are not able to accurately read people who have darker skin tones. Thus, people with darker skin tones are not able to receive proper health care due to their pulse oximetry data being inaccurate. This …


Artificial Intelligence In Neuroradiology: A Scoping Review Of Some Ethical Challenges, Pegah Khosravi, Mark Schweitzer May 2023

Artificial Intelligence In Neuroradiology: A Scoping Review Of Some Ethical Challenges, Pegah Khosravi, Mark Schweitzer

Publications and Research

Artificial intelligence (AI) has great potential to increase accuracy and efficiency in many aspects of neuroradiology. It provides substantial opportunities for insights into brain pathophysiology, developing models to determine treatment decisions, and improving current prognostication as well as diagnostic algorithms. Concurrently, the autonomous use of AI models introduces ethical challenges regarding the scope of informed consent, risks associated with data privacy and protection, potential database biases, as well as responsibility and liability that might potentially arise. In this manuscript, we will first provide a brief overview of AI methods used in neuroradiology and segue into key methodological and ethical challenges. …


Feature Selection From Clinical Surveys Using Semantic Textual Similarity, Benjamin Warner May 2023

Feature Selection From Clinical Surveys Using Semantic Textual Similarity, Benjamin Warner

McKelvey School of Engineering Graduate Student Theses & Dissertations

Survey data collected from human subjects can contain a high number of features while having a comparatively low quantity of examples. Machine learning models that attempt to predict outcomes from survey data under these conditions can overfit and result in poor generalizability. One remedy to this issue is feature selection, which attempts to select an optimal subset of features to learn upon. A relatively unexplored source of information in the feature selection process is the usage of textual names of features, which may be semantically indicative of which features are relevant to a target outcome. The relationships between feature names …


Optimizing Tumor Xenograft Experiments Using Bayesian Linear And Nonlinear Mixed Modelling And Reinforcement Learning, Mary Lena Bleile May 2023

Optimizing Tumor Xenograft Experiments Using Bayesian Linear And Nonlinear Mixed Modelling And Reinforcement Learning, Mary Lena Bleile

Statistical Science Theses and Dissertations

Tumor xenograft experiments are a popular tool of cancer biology research. In a typical such experiment, one implants a set of animals with an aliquot of the human tumor of interest, applies various treatments of interest, and observes the subsequent response. Efficient analysis of the data from these experiments is therefore of utmost importance. This dissertation proposes three methods for optimizing cancer treatment and data analysis in the tumor xenograft context. The first of these is applicable to tumor xenograft experiments in general, and the second two seek to optimize the combination of radiotherapy with immunotherapy in the tumor xenograft …


Personalized Health Care In A Data-Driven Era: A Post–Covid-19 Retrospective, Arnob Zahid, Ravishankar Sharma May 2023

Personalized Health Care In A Data-Driven Era: A Post–Covid-19 Retrospective, Arnob Zahid, Ravishankar Sharma

All Works

No abstract provided.


Du Undergraduate Showcase: Research, Scholarship, And Creative Works, Caitlyn Aldersea, Justin Bravo, Sam Allen, Anna Block, Connor Block, Emma Buechler, Maria De Los Angeles Bustillos, Arianna Carlson, William Christensen, Olivia Kachulis, Noah Craver, Kate Dillon, Muskan Fatima, Angel Fernandes, Emma Finch, Colleen Cassidy, Amy Fishman, Andrea Francis, Stacia Fritz, Simran Gill, Emma Gries, Rylie Hansen, Shannon Powers, Jacqueline Martinez, Zachary Harker, Ashley Hasty, Mykaela Tanino-Springsteen, Kathleen Hopps, Adelaide Kerenick, Colin Kleckner, Ci Koehring, Elijah Kruger, Braden Krumholz, Maddie Leake, Lyneé Alves, Seraphina Loukas, Yatzari Lozano Vazquez, Haley Maki, Emily Martinez, Sierra Mckinney, Audrey Mitchell, Kipling Newman, Audrey Ng, Megan Lucyshyn, Andrew Nguyen, Stevie Ostman, Casandra Pearson, Alexandra Penney, Julia Gielczynski, Tyler Ball, Anna Rini, Christina Rorres, Simon Ruland, Helayna Schafer, Emma Sellers, Sarah Schuller, Claire Shaver, Kevin Summers, Isabella Shaw, Madison Sinar, Claudia Pena, Apshara Siwakoti, Carter Sorensen, Madi Sousa, Anna Sparling, Alexandra Revier, Brandon Thierry, Dylan Tyree, Maggie Williams, Lauren Wols May 2023

Du Undergraduate Showcase: Research, Scholarship, And Creative Works, Caitlyn Aldersea, Justin Bravo, Sam Allen, Anna Block, Connor Block, Emma Buechler, Maria De Los Angeles Bustillos, Arianna Carlson, William Christensen, Olivia Kachulis, Noah Craver, Kate Dillon, Muskan Fatima, Angel Fernandes, Emma Finch, Colleen Cassidy, Amy Fishman, Andrea Francis, Stacia Fritz, Simran Gill, Emma Gries, Rylie Hansen, Shannon Powers, Jacqueline Martinez, Zachary Harker, Ashley Hasty, Mykaela Tanino-Springsteen, Kathleen Hopps, Adelaide Kerenick, Colin Kleckner, Ci Koehring, Elijah Kruger, Braden Krumholz, Maddie Leake, Lyneé Alves, Seraphina Loukas, Yatzari Lozano Vazquez, Haley Maki, Emily Martinez, Sierra Mckinney, Audrey Mitchell, Kipling Newman, Audrey Ng, Megan Lucyshyn, Andrew Nguyen, Stevie Ostman, Casandra Pearson, Alexandra Penney, Julia Gielczynski, Tyler Ball, Anna Rini, Christina Rorres, Simon Ruland, Helayna Schafer, Emma Sellers, Sarah Schuller, Claire Shaver, Kevin Summers, Isabella Shaw, Madison Sinar, Claudia Pena, Apshara Siwakoti, Carter Sorensen, Madi Sousa, Anna Sparling, Alexandra Revier, Brandon Thierry, Dylan Tyree, Maggie Williams, Lauren Wols

DU Undergraduate Research Journal Archive

DU Undergraduate Showcase: Research, Scholarship, and Creative Works


Integrating Ai Into Culinary Medicine: A Revolution In Nutrition And Home Cooking, Emeka Ikeakanam, Evan Curry, Terrence Mchugh, Jason Walker May 2023

Integrating Ai Into Culinary Medicine: A Revolution In Nutrition And Home Cooking, Emeka Ikeakanam, Evan Curry, Terrence Mchugh, Jason Walker

Research Day

Introduction

With the growing popularity of the emerging field of culinary medicine, there is a growing understanding of the culinary barriers needed to be overcome to adopt healthier eating habits. Lack of confidence, low skills, and lack of time are some of the most common barriers that prevent individuals from cooking at home. However, integrating AI can offer personalized support for home cooking and help individuals overcome these barriers. AI-powered meal planning and recipe suggestions can guide healthy and nutritious food choices that cater to their dietary needs and preferences. Additionally, AI can modify recipes to accommodate individual health conditions …


Combining Frameworks To Improve Military Health System Quality And Cybersecurity, Dr. Maureen L. Schafer, Dr. Joseph H. Schafer May 2023

Combining Frameworks To Improve Military Health System Quality And Cybersecurity, Dr. Maureen L. Schafer, Dr. Joseph H. Schafer

Military Cyber Affairs

Existing conceptual frameworks and commercially available technology could be considered to rapidly operationalize the use of Quality Measures (QM) within military health systems (Costantino et al. 2020). Purchased healthcare as well as digital healthcare services have paved the way for data collection from multiple information systems thus offering stakeholders actionable intelligence to both guide and measure healthcare outcomes. However, the collection of data secondary to Smart Devices, disparate information systems, cloud services, and the Internet of Medical Things (IOMT) is a complication for security experts that also affect clients, stakeholders, organizations, and businesses delivering patient care. We have combined three …


Interdisciplinary And Innovative: A Nursing And Computer Science Collaboration To Create A Barcode Medication Administration System, Jodi Lisbeth Berndt, Peter Ohmann, Imad Rahal, Lindsey Hoeschen, Andrew Rothstein May 2023

Interdisciplinary And Innovative: A Nursing And Computer Science Collaboration To Create A Barcode Medication Administration System, Jodi Lisbeth Berndt, Peter Ohmann, Imad Rahal, Lindsey Hoeschen, Andrew Rothstein

Nursing Faculty Publications

Preventing medication errors remains a priority in nursing education. The implementation of Barcode Medication Administration (BCMA) systems is one strategy that has been used to reduce medication errors. Practice using BCMA in simulated settings may enhance the transfer of these skills to the clinical practice setting. However, the purchase of BCMA educational products available for nursing students can be cost prohibitive for many nursing programs. To overcome the barrier of cost, an interdisciplinary and innovative collaborative approach was used to create a fully functional low-cost BCMA system.


Multiple Sequence Alignment Guided By Clam, Emily Light May 2023

Multiple Sequence Alignment Guided By Clam, Emily Light

Senior Honors Projects

For my honors project, I am continuing my research with my academic advisor, Dr. Daniels on creating an approach to the Multiple Sequence Alignment problem in the Rust programming language. This approach will be attached to Dr. Daniels’ CLAM (Clustered Learning for Approximate Manifolds) to enable it to globally and locally align DNA sequences. This research was divided into three separate parts: building the algorithms, implementing them into CLAM’s metric, and measuring and improving the performance of the algorithms. This project includes two separate but related algorithms; Needleman-Wunsch algorithm and the Smith-Waterman algorithm.

The Needleman-Wunsch algorithm takes in two DNA …


Development Of A Cost-Constrained Intelligent Prosthetic Knee With Real-Time Machine Learning, Predictive Stumble Control, Lucas Jonathan Galey May 2023

Development Of A Cost-Constrained Intelligent Prosthetic Knee With Real-Time Machine Learning, Predictive Stumble Control, Lucas Jonathan Galey

Open Access Theses & Dissertations

The field of biomechatronics is evolving quickly with advances in computer science, biology, and electrical and mechanical engineering. Coupled with increased interests in machine learning (ML) across all industry sectors, there are opportunities to leverage advanced analytics in uniquely complex problems. This study aimed to deploy real-time ML predictions in a novel microprocessor-controlled prosthetic knee (MPK) device capable of identifying and responding to stumble-events to reduce amputee fall prevalence. Innately, stumbling is a chaotic event. Current MPKs operate by detecting gait characteristics and reacting to preprogrammed states. While these systems are beneficial in significant ways, such as energy expenditure and …


Enhanced Iot-Based Electrocardiogram Monitoring System With Deep Learning, Jian Ni May 2023

Enhanced Iot-Based Electrocardiogram Monitoring System With Deep Learning, Jian Ni

UNLV Theses, Dissertations, Professional Papers, and Capstones

Due to the rapid development of computing and sensing technologies, Internet of Things (IoT)-based cardiac monitoring plays a crucial role in providing patients with cost-efficient solutions for long-term, continuous, and pervasive electrocardiogram (ECG) monitoring outside a hospital setting. In a typical IoT-based ECG monitoring system, ECG signals are picked up by sensors located on the edge, and then uploaded to the remote cloud servers. ECG interpretation is performed for the collected ECGs in the cloud servers and the analysis results can be made instantly available to the patients as well as their healthcare providers.In this dissertation, we first examine the …


Multiparametric Magnetic Resonance Imaging Artificial Intelligence Pipeline For Oropharyngeal Cancer Radiotherapy Treatment Guidance, Kareem Wahid May 2023

Multiparametric Magnetic Resonance Imaging Artificial Intelligence Pipeline For Oropharyngeal Cancer Radiotherapy Treatment Guidance, Kareem Wahid

Dissertations and Theses (Open Access)

Oropharyngeal cancer (OPC) is a widespread disease and one of the few domestic cancers that is rising in incidence. Radiographic images are crucial for assessment of OPC and aid in radiotherapy (RT) treatment. However, RT planning with conventional imaging approaches requires operator-dependent tumor segmentation, which is the primary source of treatment error. Further, OPC expresses differential tumor/node mid-RT response (rapid response) rates, resulting in significant differences between planned and delivered RT dose. Finally, clinical outcomes for OPC patients can also be variable, which warrants the investigation of prognostic models. Multiparametric MRI (mpMRI) techniques that incorporate simultaneous anatomical and functional information …


Automating The Radiation Therapy Treatment Planning Process For Pediatric Patients With Medulloblastoma, Soleil Hernandez May 2023

Automating The Radiation Therapy Treatment Planning Process For Pediatric Patients With Medulloblastoma, Soleil Hernandez

Dissertations and Theses (Open Access)

Over the past 50 years, pediatric cancer 5-year survival rates increased from 20% to 80% in high-income countries, however, these trends have not been mirrored in low-and-middle-income countries (LMICs). This is due in part to delayed diagnosis, higher rates of advanced disease at presentation and a growing lack of access to high quality medical personnel and technology necessary to deliver complex treatments.

The long-term goal of this study was to alleviate demanding workflows and increase global access to high-quality pediatric radiation therapy by harnessing the power of artificial intelligence to automate the radiation therapy treatment planning process for pediatric patients …


Exploring A Gradient-Based Explainable Ai Technique For Time-Series Data: A Case Study Of Assessing Stroke Rehabilitation Exercises, Min Hun Lee, Yi Jing Choy May 2023

Exploring A Gradient-Based Explainable Ai Technique For Time-Series Data: A Case Study Of Assessing Stroke Rehabilitation Exercises, Min Hun Lee, Yi Jing Choy

Research Collection School Of Computing and Information Systems

Explainable artificial intelligence (AI) techniques are increasingly being explored to provide insights into why AI and machine learning (ML) models provide a certain outcome in various applications. However, there has been limited exploration of explainable AI techniques on time-series data, especially in the healthcare context. In this paper, we describe a threshold-based method that utilizes a weakly supervised model and a gradient-based explainable AI technique (i.e. saliency map) and explore its feasibility to identify salient frames of time-series data. Using the dataset from 15 post-stroke survivors performing three upper-limb exercises and labels on whether a compensatory motion is observed or …


Risk Assessment Framework For Evaluation Of Cybersecurity Threats And Vulnerabilities In Medical Devices, Maureen S. Van Devender May 2023

Risk Assessment Framework For Evaluation Of Cybersecurity Threats And Vulnerabilities In Medical Devices, Maureen S. Van Devender

Graduate Theses and Dissertations (2019 - present)

Medical devices are vulnerable to cybersecurity exploitation and, while they can provide improvements to clinical care, they can put healthcare organizations and their patients at risk of adverse impacts. Evidence has shown that the proliferation of devices on medical networks present cybersecurity challenges for healthcare organizations due to their lack of built-in cybersecurity controls and the inability for organizations to implement security controls on them. The negative impacts of cybersecurity exploitation in healthcare can include the loss of patient confidentiality, risk to patient safety, negative financial consequences for the organization, and loss of business reputation. Assessing the risk of vulnerabilities …


Inaugural Artificial Intelligence For Public Health Practice (Ai4php) Retreat: Ontario, Canada, Jacqueline K. Kueper, Laura C. Rosella, Richard G. Booth, Brent D. Davis, Sarah Nayani, Maxwell J. Smith, Dan Lizotte Apr 2023

Inaugural Artificial Intelligence For Public Health Practice (Ai4php) Retreat: Ontario, Canada, Jacqueline K. Kueper, Laura C. Rosella, Richard G. Booth, Brent D. Davis, Sarah Nayani, Maxwell J. Smith, Dan Lizotte

Computer Science Publications

The Artificial Intelligence (AI) for Public Health Practice Retreat was a hybrid event held in October 2022 in London, Ontario to achieve three main goals: 1) Identify both the goals of public health practitioners and the tasks that they undertake as part of their practice to achieve those goals that could be supported by AI, 2) Learn from existing examples and the experience of others about facilitators and barriers to AI for public health, and 3) Support new and strengthen existing connections between public health practitioners and AI researchers. The retreat included a keynote presentation, group brainstorming exercises, breakout group …


Head And Neck Tumor Histopathological Image Representation With Pre- Trained Convolutional Neural Network And Vision Transformer, Ranny Rahaningrum Herdiantoputri, Daisuke Komura, Tohru Ikeda, Shumpei Ishikawa Apr 2023

Head And Neck Tumor Histopathological Image Representation With Pre- Trained Convolutional Neural Network And Vision Transformer, Ranny Rahaningrum Herdiantoputri, Daisuke Komura, Tohru Ikeda, Shumpei Ishikawa

Journal of Dentistry Indonesia

Image representation via machine learning is an approach to quantitatively represent histopathological images of head and neck tumors for future applications of artificial intelligence-assisted pathological diagnosis systems. Objective: This study compares image representations produced by a pre-trained convolutional neural network (VGG16) to those produced by a vision transformer (ViT-L/14) in terms of the classification performance of head and neck tumors. Methods: W hole-slide images of five oral t umor categories (n = 319 cases) were analyzed. Image patches were created from manually annotated regions at 4096, 2048, and 1024 pixels and rescaled to 256 pixels. Image representations were …


The Impact Of Virtual Reality On The Healthcare Industry, Peter Sullivan Apr 2023

The Impact Of Virtual Reality On The Healthcare Industry, Peter Sullivan

Honors Projects in Information Systems and Analytics

Virtual reality (VR) took off in 2013 and has touched many public sectors, from gaming, to business, to healthcare. This study looks at virtual reality's impact has affected the healthcare system, with a focus on its use for medical training, patient recovery, patient pain management, and mental health care. A literature review was conducted on the current state of the industry addressing virtual reality's performance in the field, the perception of experts, and an estimation of financial undertakings. Looking at cost analyses brought a fuller approach to the research. Surveying researchers and workers within the realm of healthcare and VR …


From Deep Mutational Mapping Of Allosteric Protein Landscapes To Deep Learning Of Allostery And Hidden Allosteric Sites: Zooming In On “Allosteric Intersection” Of Biochemical And Big Data Approaches, Gennady M. Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao Apr 2023

From Deep Mutational Mapping Of Allosteric Protein Landscapes To Deep Learning Of Allostery And Hidden Allosteric Sites: Zooming In On “Allosteric Intersection” Of Biochemical And Big Data Approaches, Gennady M. Verkhivker, Mohammed Alshahrani, Grace Gupta, Sian Xiao, Peng Tao

Mathematics, Physics, and Computer Science Faculty Articles and Research

The recent advances in artificial intelligence (AI) and machine learning have driven the design of new expert systems and automated workflows that are able to model complex chemical and biological phenomena. In recent years, machine learning approaches have been developed and actively deployed to facilitate computational and experimental studies of protein dynamics and allosteric mechanisms. In this review, we discuss in detail new developments along two major directions of allosteric research through the lens of data-intensive biochemical approaches and AI-based computational methods. Despite considerable progress in applications of AI methods for protein structure and dynamics studies, the intersection between allosteric …