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Full-Text Articles in Computer Sciences

An Evaluation Of Artificial Intelligence Chatbots As Alternatives To Specialized Software In Teaching Bayesian Pharmacokinetic Analysis, Reza Mehvar May 2026

An Evaluation Of Artificial Intelligence Chatbots As Alternatives To Specialized Software In Teaching Bayesian Pharmacokinetic Analysis, Reza Mehvar

Pharmacy Faculty Articles and Research

Objective

To investigate the accuracy and reliability of artificial intelligence chatbots in estimating pharmacokinetic parameters from limited patient samples and population data for potential application in teaching Bayesian concepts.

Methods

Two plasma concentration–time data sets after a single intravenous dose, along with population values for volume of distribution (V) and elimination rate constant (k), were entered into free versions of ChatGPT and Gemini. Three prompts were engineered to assess and improve the accuracy and consistency of patient-only (based on plasma concentrations) and Bayesian (based on plasma concentrations and population data) estimates of V and k. …


The Making Of An Extremist: How Do We Become Someone Else’S Nightmare?, María Paula Morales May 2026

The Making Of An Extremist: How Do We Become Someone Else’S Nightmare?, María Paula Morales

The Confluence

This article explores how ordinary people can be pulled into extremist movements and what psychological forces drive that process. It looks at three perspectives: social identity theory, which explains how group belonging shapes behavior, identity development, which shows how people searching for meaning may find it in extremist causes; and social neuroscience, which connects radicalization to brain activity linked to fear, loyalty, and moral judgement. Together, these approaches show that radicalization is not simply about ideology but about identity, emotion, and belonging. By understanding these dynamics, we can find better ways to prevent extremism and promote healthier, more inclusive communities.


Agentic Scientific Machine Learning For Autonomous Model Discovery In Systems Pharmacology, Nazanin Ahmadi, George Karniadakis May 2026

Agentic Scientific Machine Learning For Autonomous Model Discovery In Systems Pharmacology, Nazanin Ahmadi, George Karniadakis

Biology and Medicine Through Mathematics Conference

No abstract provided.


Psychiatry Meets Ai: Are Residents Ready?, Jacob De Castro, John Case May 2026

Psychiatry Meets Ai: Are Residents Ready?, Jacob De Castro, John Case

Rowan-Virtua Research Day

Artificial intelligence (AI) use is increasing in healthcare, but psychiatry residency training remains unstructured. In a 20-resident pilot survey, AI was frequently used for literature review and clinical support, with limited confidence and institutional guidance. We found most residents desired formal training and would use AI more if institutionally supported. Findings highlight a gap between rapid adoption and structured education.


Ai-Augmented Digital Auscultation For Point-Of-Care Screening Of Valvular Heart Disease: A Systematic Review And Meta-Analysis, Harshal Parmar, Akhila Archakam, Nikhila Archakam, Wesley Kim, Eduard Koman Md May 2026

Ai-Augmented Digital Auscultation For Point-Of-Care Screening Of Valvular Heart Disease: A Systematic Review And Meta-Analysis, Harshal Parmar, Akhila Archakam, Nikhila Archakam, Wesley Kim, Eduard Koman Md

Rowan-Virtua Research Day

Background: Valvular heart disease (VHD) affects >10% of adults aged 75+ yet remains underdiagnosed when asymptomatic due to declining auscultatory proficiency. AI-augmented digital auscultation offers a point-of-care screening solution, though no meta-analysis has pooled diagnostic accuracy across VHD subtypes in adults using echocardiography as the reference.

Methods: A systematic review and meta-analysis were conducted per PRISMA guidelines. PubMed, Embase, Cochrane, IEEE Xplore, and Scopus were searched without date restriction. Studies applying AI or machine learning to digital auscultation or phonocardiography for VHD classification in adults with echocardiographic reference and patient-level diagnostic metrics were included. Studies using only public datasets, pediatric …


Developing A Comprehensive Resource Guide For Caregivers Within The Area Agency On Aging, Aiden R. Murphy May 2026

Developing A Comprehensive Resource Guide For Caregivers Within The Area Agency On Aging, Aiden R. Murphy

Public Health Capstone Projects

This project developed a new universal caregiver resource guide for caregivers within the Area Agency on Aging, in order to improve resource navigation and workflow efficiency. Resources were collected, verified, and organized into a new, streamlined guide via the ARIA chatbot, covering multiple needs. Caregiver resources were collected and verified by the capstone student and mentor, Michael Kroeker, and organized into a centralized knowledge base within the ARIA chatbot. A mixed methods evaluation was conducted utilizing a 5-point Likert scale with three quantitative questions and one open-ended qualitative question. The data was given to the SeniorLine staff, who wanted to …


Predicting And Decoding Allosteric Binding Sites Using Protein Language Models And Structure-Based Machine Learning: An Energy Landscape-Guided Explainable Ai Framework, Kamila Riedlová, Vít Skrhák, William G. Gatlin, Max Ludwick, Lucas Turano, Marian Novotný, David Hoksza, Gennady M. Verkhivker May 2026

Predicting And Decoding Allosteric Binding Sites Using Protein Language Models And Structure-Based Machine Learning: An Energy Landscape-Guided Explainable Ai Framework, Kamila Riedlová, Vít Skrhák, William G. Gatlin, Max Ludwick, Lucas Turano, Marian Novotný, David Hoksza, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Computational prediction of allosteric binding sites in protein structures remains a persistent challenge, as these regulatory pockets evade detection by both sequence-based and structure-based algorithms. Both computational and physical origins of this predictive asymmetry remain insufficiently understood. In this study, we systematically examine the determinants of binding site predictability using a dual framework that integrates a fine-tuned protein language model and the structure-based method P2Rank as complementary tools probing a diverse data set of 453 human kinases, together with a physics-based interpretability layer derived from energy landscape frustration analysis. Both predictors exhibit a sharp and reproducible dichotomy on protein kinases, …


Faircarenlp: An Ai-Driven Patient Review Analyzer For Healthcare, Sayyed Mohammad Pourya Momtaz Esfahani, Davey Seeman, Christoffer Dharma, Mohammad Noaeen, Shion Guha, Zahra Shakeri May 2026

Faircarenlp: An Ai-Driven Patient Review Analyzer For Healthcare, Sayyed Mohammad Pourya Momtaz Esfahani, Davey Seeman, Christoffer Dharma, Mohammad Noaeen, Shion Guha, Zahra Shakeri

Health Services and Informatics Research

Objective

To develop and evaluate an automatic patient review analyzer that applies advanced Natural Language Processing (NLP) and machine learning methods to improve the efficiency, fairness, and accuracy of healthcare feedback analysis.

Materials and methods

We designed a multi-component pipeline incorporating sentiment analysis, key theme extraction, clinical Named Entity Recognition (NER), and fairness modules. Bias mitigation was addressed through the integration of three complementary approaches: adversarial debiasing, Hard Debiasing, and Iterative Null-space Projection (INLP). Multiple BERT-based models (DistilBERT, BioBERT, RoBERTa-base, BERT-base-uncased) were trained and evaluated under varying hyperparameters and fairness/adversarial loss configurations. Model performance was assessed using accuracy, F1, recall, …


Utilizing Brain Computer Interfaces That Interact With A Virtual Keyboard, Skye Lilienthal May 2026

Utilizing Brain Computer Interfaces That Interact With A Virtual Keyboard, Skye Lilienthal

Honors Theses

A brain-computer interface (BCI) can allow someone to utilize electrical signals in their brain to complete tasks using a computer. BCIs can help people take advantage of technology to type without the need for a traditional keyboard setup. This paper used the OpenBCI Mark IV to test the effectiveness of non-invasive BCIs with dry electrodes within the OpenViBE P300 Speller. This paper shows how to use the P300 speller through a setup pipeline. Results indicate that electrode placement affects P300 accuracy and that areas related to visual processing improve accuracy, suggesting that P300 signals can be detected within OpenBCI Mark …


Public Health Responsible Ai Capability (Ph-Raic) Framework: A Conceptual Model For Integrating Ai Into Public Health Agencies, Arnob Zahid, Ravishankar Sharma, Rezwan Ahmed May 2026

Public Health Responsible Ai Capability (Ph-Raic) Framework: A Conceptual Model For Integrating Ai Into Public Health Agencies, Arnob Zahid, Ravishankar Sharma, Rezwan Ahmed

All Works

Background: Artificial intelligence (AI) is transitioning from experimental pilots to core public health functions such as disease surveillance, resource planning, and analysis of social and structural determinants of health. Yet, health data collection and stewardship remain fragmented across the globe; some jurisdictions still rely on paper-based systems, while others operate noninteroperable digital systems that can exacerbate inequities. Treating health data as a global good therefore requires governance that enables innovation while protecting rights, safety, and trust. This study aims to develop a conceptual meso-level capability framework that translates responsible AI principles into organizational practices for public health agencies. Methods: We …


From Data Digitization To Personalized Care: Deep Learning And Decision Analytics In Healthcare Systems, Ahla Ko May 2026

From Data Digitization To Personalized Care: Deep Learning And Decision Analytics In Healthcare Systems, Ahla Ko

Graduate Theses and Dissertations

This dissertation traces a progression from foundational data infrastructure to individualized clinical decision-making, developing and evaluating three computational frameworks that advance healthcare efficiency and personalization through deep learning and decision analytics. The first study presents an end-to-end pipeline for automated recognition of handwritten medical forms, addressing persistent challenges in health data digitization. Integrating a YOLO-based field detection model, a Convolutional Recurrent Neural Network (CRNN) for text transcription, and a confidence-based human-in-the-loop quality assurance framework, the system achieved 99.75\% Exact Match Accuracy and a 0.13\% Character Error Rate on medical forms collected from a tuberculosis research project in Moldova. A GPU-accelerated …


Volume 17, Christian O’Neill, Kyara Greene, Savva Sidorov, Laura Bisaillon, Luke Clemmer, Hannah Gordon, Kitt Benson, Taylor Blount, Rachel Danzitz, Nicholas Duellman, Chase Gionis, Hima Fernando, Seth Franzyshen, Onyx Gonzalez, Bryan Lin, Samantha Start, Ysabel Wells, Maggie Duncan May 2026

Volume 17, Christian O’Neill, Kyara Greene, Savva Sidorov, Laura Bisaillon, Luke Clemmer, Hannah Gordon, Kitt Benson, Taylor Blount, Rachel Danzitz, Nicholas Duellman, Chase Gionis, Hima Fernando, Seth Franzyshen, Onyx Gonzalez, Bryan Lin, Samantha Start, Ysabel Wells, Maggie Duncan

Incite: The Journal of Undergraduate Scholarship

Introduction Dr. Amorette Barber, Director, Office of Student Research

From the Editor Dr. Hannah Dudley-Shotwell

Cover Artist’s Statement Maggie Duncan

On Mentoring Dr. Yulia Uryadova

Ukrainian Resistance in the Face of Russification: Nestor Makhno and Anarchism

by Christian O’Neill

Life Vest by Kyara Greene

Isolation and 16S rRNA Identification of Bacteria from Fire Department Connection Pipe by Savva Sidorov

The Effectiveness of Planned Exercise in Reducing ADHD Symptoms in Children by Laura Bisaillon & Luke Clemmer

Linguistic Analysis on Confidence and Communication Strategies with Disparities Between Sign Fluency and Hearing Impairment by Hannah Gordon

Freedmen in Indian Territory by Kitt …


Smart Medical Support System And Swin Transformer Framework For Breast Cancer Detection And Segmentation In Mammograms, Ahed Abugabah, Prashant Kumar Shukla, Piyush Kumar Shukla, Abhishek Dwivedi May 2026

Smart Medical Support System And Swin Transformer Framework For Breast Cancer Detection And Segmentation In Mammograms, Ahed Abugabah, Prashant Kumar Shukla, Piyush Kumar Shukla, Abhishek Dwivedi

All Works

Accurate and reliable breast cancer detection from mammographic images remains a critical challenge due to subtle lesion appearance, high intra-class variability, and class imbalance inherent in clinical datasets. To address these issues, this study proposes Swin-BreastNet, an explainable and optimization-driven deep learning framework for binary classification of benign and malignant breast lesions from full-field digital mammograms. The proposed approach leverages the hierarchical Swin Transformer model to effectively capture fine-grained local texture patterns and long-range contextual dependencies through Shifted Window Multi-head Self-Attention (SW-MSA). A key novelty of this work lies in the integration of Harris Hawks Optimization (HHO) for automated hyperparameter …


Dementia Detection In Low-Resource Languages: Evaluating Translation-Assisted Transfer Learning For Multilingual Clinical Assessment, Kylar A. Deloach Apr 2026

Dementia Detection In Low-Resource Languages: Evaluating Translation-Assisted Transfer Learning For Multilingual Clinical Assessment, Kylar A. Deloach

Honors Theses

Alzheimer's disease (AD) is a growing global health concern, with millions of people affected worldwide and cases expected to rise significantly in the coming decades. Early detection is critical for patient treatment and care, and recent advances in natural language processing (NLP) have shown promise in identifying linguistic markers associated with AD. However, most existing work has focused on English, leaving speakers of other languages with limited access to such tools. This study investigates how effective AD detection models trained on English data are at transferring to Greek, a low-resource language with limited dementia-related speech data available. We propose a …


Drug Risk Knowledge Discovery For Western Medicines Based On Knowledge Graph Link Prediction, Jianxiang Wei, Ma Hengyuan Ma, Yuehong Sun, Wenwen Du, Letian Hu Apr 2026

Drug Risk Knowledge Discovery For Western Medicines Based On Knowledge Graph Link Prediction, Jianxiang Wei, Ma Hengyuan Ma, Yuehong Sun, Wenwen Du, Letian Hu

Journal of Scientific Information Research

[Purpose/significance] The risk information contained in drug instructions is usually incomplete, and some new adverse reactions can only be discovered in actual clinical use. This paper proposes an information organization and knowledge discovery method for pharmacovigilance, in order to timely and accurately identify missing risk knowledge in drug instructions. [Method/process] Drug instructions of 8 152 Western medicines are collected as the research data; On the basis of ontology construction, data annotation, and model training, the UIE model is used to jointly extract entity and relationship triplets from the research data; A new knowledge graph link prediction method CompGCN-RotatE, is proposed, …


Research On Temporal Knowledge Graph Completion Method For Emergent Events Based On Bigru And Graph Contrastive Learning, Peng Wu, Zhenyu Lu, Xuechen Zhang Apr 2026

Research On Temporal Knowledge Graph Completion Method For Emergent Events Based On Bigru And Graph Contrastive Learning, Peng Wu, Zhenyu Lu, Xuechen Zhang

Journal of Scientific Information Research

[Purpose/significance] During emergencies, social media short texts contain critical information but are heavily interfered with by noise. Traditional static knowledge graph completion techniques struggle to effectively address their dynamic evolution and data sparsity issues, making it imperative to introduce temporal modeling methods. [Method/process] This study proposes a dynamic completion framework that combines the temporal feature capture capability of Bidirectional Gated Recurrent Units (BiGRU) with the noise-resistant representation learning advantages of Graph Contrastive Learning (GCL). At the completion level, the ConBiTE method is introduced, which captures temporal dependencies through self-attention mechanisms and BiGRU, while leveraging GCL to enhance the completion of …


Spatial Computing With The Apple Vision Pro In Minimally Invasive Procedure Simulation: A Randomized Crossover Feasibility Study, Sydney Cooper, Aaron Kyle Jones, Rahul Anil Sheth, Koustav Pal, Bruno Odisio, Mark Blaylock, Shelita Kimble, Justin Bird, David Rice, Daniel Shoenthal, Emil Patel, Vipin Kamath, Sanjay Gupta, Jeffrey Siewerdsen, Joshua Kuban Apr 2026

Spatial Computing With The Apple Vision Pro In Minimally Invasive Procedure Simulation: A Randomized Crossover Feasibility Study, Sydney Cooper, Aaron Kyle Jones, Rahul Anil Sheth, Koustav Pal, Bruno Odisio, Mark Blaylock, Shelita Kimble, Justin Bird, David Rice, Daniel Shoenthal, Emil Patel, Vipin Kamath, Sanjay Gupta, Jeffrey Siewerdsen, Joshua Kuban

Advances in Cancer Education and Quality Improvement

Purpose: This study aimed to evaluate the feasibility of wearing the Apple Vision Pro (AVP), a mixed-reality headset that integrates augmented and virtual reality, while performing minimally invasive procedures. While studies have demonstrated that spatial computing technology can improve surgical precision and reduce the risks of surgical complications, to our knowledge, no studies have specifically addressed the impact of the AVP on task performance during simulated image-guided procedures.

Materials and Methods: Thirteen diagnostic and interventional radiology residents performed image-guided central venous catheter placement, thoracentesis, and paracentesis on simulation models. Each participant completed a non-timed practice followed by the procedures once …


A Backend Database Architecture For Persistent Epilepsy Classification Records, Attiksh A. Panda, Deep Desai, Artem Zabarov, Katrina D. Prantzalos, Satya S. Sahoo, Shuai Xu Apr 2026

A Backend Database Architecture For Persistent Epilepsy Classification Records, Attiksh A. Panda, Deep Desai, Artem Zabarov, Katrina D. Prantzalos, Satya S. Sahoo, Shuai Xu

Student Scholarship

Epilepsy affects over five million people globally each year, yet consistent clinical diagnosis remains a persistent challenge due to the lack of standardized classification workflows across medical institutions. The Four-Dimensional Epilepsy Classification (4D-EC) framework, developed by Lüders et al., provides a comprehensive structure for characterizing paroxysmal events across four dimensions: seizure semiology, epileptogenic zone, etiology, and comorbidities. Despite its clinical and educational value, no dedicated informatics platform existed to support its routine use until recently, limiting widespread adoption among clinicians and trainees. This project addresses that gap by implementing a full-stack web application that operationalizes the 4D-EC framework for clinical …


Ai’S Role In Searching For Evidence: Friend And Foe, Barbara (Basia) Delawska-Elliott, Brandon Wilkinson Apr 2026

Ai’S Role In Searching For Evidence: Friend And Foe, Barbara (Basia) Delawska-Elliott, Brandon Wilkinson

Publications 2026-present

No abstract provided.


Statistical Inference Is Not Moral Reasoning: The Case Against Ai On Hospital Ethics Boards, Elan J. Haronian Apr 2026

Statistical Inference Is Not Moral Reasoning: The Case Against Ai On Hospital Ethics Boards, Elan J. Haronian

Seaver College Research And Scholarly Achievement Symposium

As generative AI becomes more integrated in healthcare, it seems inevitable that AI will eventually be used on hospital ethics committees. However, before implementation, their roles need careful consideration. Although AI promises to reduce costs, increase efficiency, and reduce human workloads, there are important ways in which it is limited, especially when human emotion and connection are crucial, as in clinical ethics boards.

In this paper, I highlight several problems preventing AI from being useful on hospital ethics boards. These include issues of opaque reasoning (the “black box” problem), liability, transparency, privacy, and consent. While there are proposed frameworks for …


Bio-Cybersecurity: Securing The Healthcare Industry, Amanda D. Coleman Apr 2026

Bio-Cybersecurity: Securing The Healthcare Industry, Amanda D. Coleman

Cybersecurity Undergraduate Research Showcase

Bio-cybersecurity refers to the aspect of cybersecurity that applies to the biological sciences and the protection of digital biomedical information. Today’s healthcare industry has evolved with the enhancement of internet and biomedical technology. While hospitals and private medical providers remain compliant with the Health Information Portability and Accountability Act (HIPAA) through traditional means of securing documented patient information, the emergence of beneficial internet-based healthcare services like virtual appointments and digital patient records requires new policies and healthcare cybersecurity frameworks to protect sensitive information from unauthorized access. This paper examines the role of cybersecurity in healthcare, the vulnerabilities that exist and …


Dermal: A Multi-Input Deep Learning Model For Improving Access To Dermatological Screening, Aubreye Freeman Apr 2026

Dermal: A Multi-Input Deep Learning Model For Improving Access To Dermatological Screening, Aubreye Freeman

ATU Scholars Symposium

According to the World Health Organization's press release on December 12, 2024, global healthcare spending is dropping significantly, leaving a large percentage of the world without proper healthcare. In an attempt to alleviate this problem, with respect to the field of dermatology, we created a deep learning model, Dermatology Enhanced by Recognition and Machine Aided Learning (DERMAL), to assist in diagnosing skin conditions. DERMAL was trained on a portion of the Google and Stanford Medicine's SCIN dataset, which has more than 10,000 images of various skin conditions. The 9 most common skin conditions of the dataset were selected as the …


Redesigning A Fitness App Interface For Physiological Constrained Users*, Joseph E. Manzanillo Apr 2026

Redesigning A Fitness App Interface For Physiological Constrained Users*, Joseph E. Manzanillo

Campus Research Month

As fitness tracking converges with medical monitoring, inclusive design becomes a matter of health equity. This research utilizes a Polar Beat redesign to address exclusionary "sporty" aesthetics that can exclude 300 million colorblind users. Based in Human-Computer Interaction (HCI), the study implements WCAG AA standards and color-blind-verified filters to mitigate data loss during Situational Induced Impairment (SIID), when high-intensity exercise compromises cognitive and visual processing. By optimizing user journeys for Paralympic and geriatric archetypes, this work demonstrates that accessibility is the essential bridge transitioning mobile fitness apps into viable, inclusive instruments for clinical medical use.


Deep Learning-Based Automated Pneumonia Detection From Chest X-Rays: A Comparative Study Of Custom Cnn And Transfer Learning Architectures, Ahmed Sajim Apr 2026

Deep Learning-Based Automated Pneumonia Detection From Chest X-Rays: A Comparative Study Of Custom Cnn And Transfer Learning Architectures, Ahmed Sajim

Honors Theses

Pneumonia is a leading global cause of mortality, claiming approximately 2.5 million lives an-nually and placing exceptional diagnostic pressure on radiologists in resource-limited settings. Manual interpretation of chest X-ray (CXR) images is time-consuming, subject to inter-observer variability, and limited by radiologist availability. This thesis presents a systematic investiga-tion into deep learning-based automated pneumonia detection comparing five convolutional neural network (CNN) architectures: a custom-designed 2D CNN and four pretrained transfer learning models—ResNet, DenseNet, MobileNet, and VGG19.

A targeted data augmentation pipeline addresses the severe class imbalance in the Kag-gle Chest X-Ray Pneumonia dataset, expanding the Normal class from 1,583 to 9,495 …


Deep Learning Based Approaches For Low Cost Defense Detection, Adele J. Noel-Rickert Apr 2026

Deep Learning Based Approaches For Low Cost Defense Detection, Adele J. Noel-Rickert

All NMU Master's Theses

Pulmonary fibrosis is a progressive interstitial lung disease characterized by the accumulation of fibrotic tissue within the lungs, leading to impaired respiratory function and reduced quality of life. Early detection is important for disease management; however, accurate diagnosis often relies on high-resolution computed tomography (CT), which may not be accessible in all clinical settings. Chest radiography provides a lower-cost and widely available imaging modality, but interpretation of chest X-rays for fibrotic disease can be challenging due to subtle radiographic patterns and overlapping anatomical structures. This thesis investigates the use of multimodal deep learning techniques to assist in pul- monary fibrosis …


Comparative Analysis Of Mlp And Cnn Models For Cardiac Arrhythmia Classification, Veltman Okey-Ejowhor, Vahid Emamian Apr 2026

Comparative Analysis Of Mlp And Cnn Models For Cardiac Arrhythmia Classification, Veltman Okey-Ejowhor, Vahid Emamian

Posters - 2026

Electrocardiogram (ECG) is a record of the electric activity of the heart over time. ECG analysis plays a pivotal role in diagnosing critical heart conditions. Significant developments have been made in the realm of deep learning and applied artificial intelligence. These deep learning models have been utilized heavily because of their ability to analyze deep morphological features of each signal. The model architecture used in this study is a convolutional neural network (CNN) combined with a multi-layered perceptron (MLP). The MLP acts as an input filter that classifies normal heartbeat signals from abnormal. The CNN is the second filter in …


Using Ai-Based Predictive Scheduling To Improve Patient Flow And Reduce Wait Times In Healthcare Clinics, Oscar Martinez Apr 2026

Using Ai-Based Predictive Scheduling To Improve Patient Flow And Reduce Wait Times In Healthcare Clinics, Oscar Martinez

Posters - 2026

  • Healthcare systems face increasing challenges in patient access and wait times
  • Average wait times for specialist care continue to rise, creating:
    • Delays in treatment
    • Reduced patient satisfaction
    • Increased system inefficiencies (Sanford, 2025)
  • A major contributor is operational bottlenecks, defined as:
    • Points of congestion that slow or disrupt service flow
  • Hospitals typically operate under process layouts, which:
    • Handle diverse patient needs
    • Reduce specialization efficiency
  • Contributing factors to bottlenecks:
    • Physician shortages and burnout
    • Administrative burden
    • Inefficient scheduling systems (Moura & Pinho, 2025)
  • AI offers potential solutions through:
    • Predictive scheduling
    • Automation of administrative processes
    • Data-driven optimization of patient flow


What Does Next-Generation Mass Spectrometry Offer For Proteomics? A Comprehensive Platform Comparison, Filipa Blasco Tavares Pereira Lopes, Daniela Schlatzer, Tara Sudhadevi, Anantha Harijith, Marzieh Ayati, Mehmet Koyutürk, Mark R. Chance Mar 2026

What Does Next-Generation Mass Spectrometry Offer For Proteomics? A Comprehensive Platform Comparison, Filipa Blasco Tavares Pereira Lopes, Daniela Schlatzer, Tara Sudhadevi, Anantha Harijith, Marzieh Ayati, Mehmet Koyutürk, Mark R. Chance

Computer Science Faculty Publications

Next-generation mass spectrometry platforms (Orbitrap Astral, timsTOF Ultra) are reshaping proteomics by enhancing analytical depth and sensitivity. We compared these platforms against Orbitrap Exploris 480 using neonatal mouse lung tissues from a bronchopulmonary dysplasia model (n = 12), employing four acquisition strategies: Exploris 480 DDA/DIA, Astral HR-DIA, and timsTOF Ultra DIA-PASEF. All platforms identified ∼4000 proteins in common, with 98% proteome coverage of data-dependent acquisition (DDA) identifications using data-independent (DIA) methods and 92% concordance between next-generation systems. Orbitrap Astral and timsTOF Ultra quantified >225,000 peptides and 13,000 proteins, representing ∼800% and ∼300% greater depth than Exploris 480 DDA, respectively. …


Multi-Modal Tensor Fusion For Alzheimer’S Disease Recognition, Mason Li, Tiffany Le, Jiajing Huang, Yuxin Wen Mar 2026

Multi-Modal Tensor Fusion For Alzheimer’S Disease Recognition, Mason Li, Tiffany Le, Jiajing Huang, Yuxin Wen

Engineering Faculty Articles and Research

Accurate and early diagnosis of Alzheimer’s disease (AD) is critical for effective intervention, disease monitoring, and patient care. Traditional diagnostic approaches rely on a single modality, such as clinical assessments, neuroimaging, or genetic markers, which may fail to capture the complex, multifaceted nature of AD. Multimodal learning has therefore been explored to integrate complementary information across data sources. However, conventional fusion strategies, including early feature concatenation and late decision-level fusion, often model modalities independently and fail to capture high-order cross-modal interactions. To address these limitations, we propose a multimodal tensor fusion network (MTFN) that integrates heterogeneous data sources, including visual …


Evolving Solutions For Red Blood Cell Preservation, Ali Alkafaji, Charles A. Elder, Mohammad Zaidi, Kavin Parthiv, Michael A. Menze Mar 2026

Evolving Solutions For Red Blood Cell Preservation, Ali Alkafaji, Charles A. Elder, Mohammad Zaidi, Kavin Parthiv, Michael A. Menze

The Cardinal Edge

In emergencies such as natural disasters, armed conflicts, or during outer space missions, the availability of transfusable blood can mean the difference between life and death. Red blood cells (RBCs) must be stored at +4 ± 2 °C and have a shelf life of just 42 days, which makes maintaining a stable blood supply during adverse conditions extraordinarily challenging. This challenge was especially apparent during the COVID-19 pandemic when hospitals faced severe blood shortages. Freeze-drying, or lyophilization, offers a promising avenue to extend the shelf life of RBCs for transfusion during crises. However, a significant hurdle in dry preservation is …