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Full-Text Articles in Medicinal-Pharmaceutical Chemistry
Cu (Ii) Catalyzed Gateways In The Synthesis Of Acridine Derivatives And Their Biological Evaluation As Anti-Cancer Drugs, Rajesh Komati
Cu (Ii) Catalyzed Gateways In The Synthesis Of Acridine Derivatives And Their Biological Evaluation As Anti-Cancer Drugs, Rajesh Komati
University of New Orleans Theses and Dissertations
Telomeres are nucleoprotein complexes found at the ends of linear eukaryotic chromosomes. Telomeres consist of a short sequence of repetitive double stranded DNA, TTAGGG repeats in humans (and all mammals), and a complex of 6 proteins, termed the shelterin complex. The length of the telomeres varies greatly between species, from approximately 300 base pairs in yeast to many 10-15 kilo bases in humans, because of the end replication problem this length get shorten with each cell division and ultimately leads to cell death. However the immortal eukaryotic cells and some transformed human cells over come this incomplete end replication problem …