Inorganic Chemistry Commons^™

Sweep, Step, Pulse, And Frequency-Based Techniques Applied To Protein Monolayer Electrochemistry At Nanoparticle Interfaces, Debbie S. Campbell-Rance, Tran T. Doan, Michael C. Leopold

Chemistry Faculty Publications

Protein monolayer electrochemistry (PME), a strategy using synthetic platforms to study the electron transfer (ET) properties of adsorbed proteins, has been successfully applied to proteins adsorbed at monolayer-protected gold cluster (MPCs) assembled films, an adsorption interface shown to be an effective alternative, compared to traditional self-assembled monolayer (SAM) films, for the immobilization and study of ET proteins. Within PME studies, cyclic voltammetry (CV) remains the most commonly applied electrochemical technique in spite of several limitations that occur when the sweep technique is used at either platform. In particular, CV for PME at MPC films results in analysis complications stemming from …