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Full-Text Articles in Inorganic Chemistry
Synthesis And Characterization Of Multifunctional Transition Metal Oxide Nanoparticles Through A Modified Sol-Gel Method With Application In Energy Storage, Julien Lombardi
Dissertations, Theses, and Capstone Projects
The Synthesis of transition metal oxide nanoparticles has been studied in great detail over the many years. The most studied transition metal oxide nanoparticles are perovskites of the ABO3 stoichiometry (A and B = transition metal) and more recently double perovskite crystal structures of the AA’BO6 or A2BB’O6 stoichiometry due to the many different properties arising from the many different combinations of elements possible. These materials have proven potentially useful in many fields, but due to properties such as ferroelectricity and ferromagnetism, the desire to integrate these materials into electronics is ever growing. Many synthesis …
Nano-Based Systems And Biomacromolecules As Carriers For Metallodrugs In Anticancer Therapy, Mina Poursharifi, Marek T. Wlodarczyk, Aneta J. Mieszawska
Nano-Based Systems And Biomacromolecules As Carriers For Metallodrugs In Anticancer Therapy, Mina Poursharifi, Marek T. Wlodarczyk, Aneta J. Mieszawska
Publications and Research
Since the discovery of cisplatin and its potency in anticancer therapy, the development of metallodrugs has been an active area of research. The large choice of transition metals, oxidation states, coordinating ligands, and different geometries, allows for the design of metal-based agents with unique mechanisms of action. Many metallodrugs, such as titanium, ruthenium, gallium, tin, gold, and copper-based complexes have been found to have anticancer activities. However, biological application of these agents necessitates aqueous solubility and low systemic toxicity. This minireview highlights the emerging strategies to facilitate the in vivo application of metallodrugs, aimed at enhancing their solubility and bioavailability, …