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Full-Text Articles in Chemistry

The Synthesis Of Zinc Oxide By Direct And Indirect Methods, Grainne Duffy Jul 2006

The Synthesis Of Zinc Oxide By Direct And Indirect Methods, Grainne Duffy

Masters

The synthesis of zinc oxide through three routes was investigated; carboxylic acid chelation, polymer assisted synthesis in an alcoholic medium and slow thermolysis of precursor. In the case of carboxylic acid chelation, it was determined that the rate at which the precursor is formed has a significant effect on the quality of zinc oxide particles produced. Investigation of the effect of concentration, pH and species of chelating agent used on the purity and structure of product was undertaken. Examination of the composition and morphology of materials produced revealed the presence of single-crystalline spheres, the packing density and aggregation morphology of …

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Synthesis Of Aspernigrin A, Erica Joerger Apr 2006

Synthesis Of Aspernigrin A, Erica Joerger

Undergraduate Theses and Capstone Projects

Aspernigrin A is a compound correlated with inhibiting the growth of cancer cells in the colon. A five-step synthesis was designed for aspernigrin A, projected to yield four intermediates and the final product. The intermediates were analyzed by high field 1HNMR and FT-IR spectroscopy before proceeding to the next step. A model pyridone ring system was successfully prepared from a commercially available pyrone precursor in two steps. These results provide a proof of concept that the synthetic scheme should successfully yield the natural product.

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1,3-Indane-Based Chromogenic Calixpyrroles With Push-Pull Chromophores: Synthesis And Anion Sensing, Ryuhei Nishiyabu, Pavel Anzenbacher Jr. Feb 2006

1,3-Indane-Based Chromogenic Calixpyrroles With Push-Pull Chromophores: Synthesis And Anion Sensing, Ryuhei Nishiyabu, Pavel Anzenbacher Jr.

Chemistry Faculty Publications

Knoevenagel condensation of 2-formyl-octamethylcalix[4]pyrrole with selected 1,3-indanedione derivatives yields calix[4]pyrrole anion sensors with push-pull chromophores displaying strong intramolecular charge transfer. The push-pull feature results in augmented signal output as well as in dramatic changes in anion selectivity exemplified by a 50-fold increase in acetate vs chloride selectivity compared to the parent calix[4]pyrrole.

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Synthesis And Anticancer Evaluation Of Some New Unsymmetrical 3,5-Diaryl-4h-1,2,4-Triazole Derivatives, Olcay Beki̇rcan, Bahi̇tti̇n Kahveci̇, Murat Küçük Jan 2006

Synthesis And Anticancer Evaluation Of Some New Unsymmetrical 3,5-Diaryl-4h-1,2,4-Triazole Derivatives, Olcay Beki̇rcan, Bahi̇tti̇n Kahveci̇, Murat Küçük

Turkish Journal of Chemistry

A series of 4-arylidenamino-4H-1,2,4-triazole derivatives (3-11) were synthesized from the treatment of 4-amino-4H-1,2,4-triazoles (2) with certain aldehydes. Compounds 3-11 were reduced with NaBH_4 to afford the corresponding 4-arylmethylenamino-4H-1,2,4-triazoles (12-20). Compounds 1-10 and 12-19 were characterized by elemental analyses and ^1H NMR, ^{13}C NMR, IR and UV spectral data. Compounds 11 and 20 were characterized by ^1H NMR, ^{13}C NMR, IR and mass spectral data. Compounds 14, 16, 17, and 18 were tested for anticancer activities. Compound 17, chosen for its higher anticancer activity in the preliminary tests with the cancer cell lines of MCF7, NCI-H460, and SF-268, exhibited remarkable anticancer …

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Synthesis And Characterization Of Metal Complexes Of Cu(Ii), Ni(Ii), Zn(Ii), Co(Ii), Mn(Ii) And Cd(Ii) With Tetradentate Schiff Bases, Jianning Liu, Bo-Wan Wu, Bing Zhang, Yongchun Liu Jan 2006

Synthesis And Characterization Of Metal Complexes Of Cu(Ii), Ni(Ii), Zn(Ii), Co(Ii), Mn(Ii) And Cd(Ii) With Tetradentate Schiff Bases, Jianning Liu, Bo-Wan Wu, Bing Zhang, Yongchun Liu

Turkish Journal of Chemistry

4-(Benzeneazo)salicylaldehyde was synthesized with aniline, sodium nitrite and salicylaldehyde. Two tetradentate ligands, N,N'-bis[4-(benzeneazo) salicylaldehyde]-o-phenylenediamine (H_2L) and N,N'-bis[4-(benzeneazo) salicylaldehyde]ethylenediamine (H_2L') were formed by the 2:1 molar condensation of 4-(benzeneazo) salicylaldehyde with o-phenylenediamine or ethylenediamine. Their Cu(II), Ni(II), Zn(II), Co(II), Mn(II) and Cd(II) complexes were synthesized and characterized by elemental analysis, molar conductivity measurements, and infrared and electronic spectral data. Two ligands and their Ni(II) and Zn(II) complexes were further identified using ^1H NMR spectra. The results suggest that the metal is bonded to the ligand through the phenolic oxygen and the imino nitrogen.

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Synthesis, Characterization, Crystal Structure And Thermal Behavior Of N'-(4-Chlorobenzoyl)-N,N-Di-N-Butylthiourea And Its Nickel Complex, Hakan Arslan, Ulrich Flörke, Nevzat Külcü, Esra Kayhan Jan 2006

Synthesis, Characterization, Crystal Structure And Thermal Behavior Of N'-(4-Chlorobenzoyl)-N,N-Di-N-Butylthiourea And Its Nickel Complex, Hakan Arslan, Ulrich Flörke, Nevzat Külcü, Esra Kayhan

Turkish Journal of Chemistry

We report the synthesis, structural characterization and thermal behavior of N'-(4-chlorobenzoyl)-N,N-di-n-butylthiourea (HL) and its nickel complex (NiL_2). Some physical properties of the prepared compounds were investigated using elemental analyses, IR, ^1H-NMR, and magnetic susceptibility. The molecular structures of HL and NiL_2 were determined by single crystal X-ray diffraction. HL is a monoclinic, space group P2_1/c with a = 10.7457(5) Å, b = 15.5909(8) Å, c = 10.4536(5) Å, \beta = 104.398(1)°, and V = 1696.34(14) Å^3 with Z = 4 for d_{calc} = 1.280 g/cm^3. NiL_2 is a triclinic, space group P-1 with a = 8.561(3) Å, b = 16.643(6) …

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The Mechanism And Crystal Structure Of 2-Methoxy-2-Methyl-4-Phenyl-3,4,4a, 10b-Tetrahydro-2h,5h-Pyrano[3,2-C]Chromen-5-One. Acetal Of Warfarin Acid, Saira Shahzadi, Saqib Ali, Irum Asif, Rizwana Ashraf, Guo-Xin Jin Jan 2006

The Mechanism And Crystal Structure Of 2-Methoxy-2-Methyl-4-Phenyl-3,4,4a, 10b-Tetrahydro-2h,5h-Pyrano[3,2-C]Chromen-5-One. Acetal Of Warfarin Acid, Saira Shahzadi, Saqib Ali, Irum Asif, Rizwana Ashraf, Guo-Xin Jin

Turkish Journal of Chemistry

Acetal of warfarin acid has been synthesized via a hemi acetal intermediate and structurally characterized by X-ray diffraction. The crystal structure shows that the title compound was formed by the hydrolysis of warfarin acid in methanol at pH 3, with space group P2_1/n and unit cell parameters a = 5.859 (17), b =16.745 (5), c = 16.402 (5) Å, \alpha = 90.00; \beta = 94.853 (4), and \gamma = 90.00°.

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Template Synthesis And Structural Characterization Of Homo Binuclear Chromium(Iii), Manganese(Iii), Iron(Iii), Cobalt(Iii), And Ruthenium(Iii) Complexes With Octaazamacrocyclic Ligands, Vinod K. Sharma, Shipra Srivastava Jan 2006

Template Synthesis And Structural Characterization Of Homo Binuclear Chromium(Iii), Manganese(Iii), Iron(Iii), Cobalt(Iii), And Ruthenium(Iii) Complexes With Octaazamacrocyclic Ligands, Vinod K. Sharma, Shipra Srivastava

Turkish Journal of Chemistry

The Schiff base octaazamacrocyclic ligands derived from primary diamines and 3,6-dimethyl/diphenyl-4,5-diazaocta-3,5-diene-2,7-dione, and their binuclear complexes [M_2LCl_4]Cl_2 [M = Cr(III), Fe(III), Co(III), or Ru(III)] and [Mn_2L(AcO)_4](AcO)_2 were synthesized by template condensation reactions. Attempts to synthesize the corresponding metal-free macrocyclic ligands did not prove successful. The overall geometry and stereochemistry of these complexes were elucidated by elemental analyses, magnetic susceptibilities, electronic spectra, infrared spectra, molar conductance measurements, ^1H NMR, and thermogravimetric analysis. All the trivalent metal ion complexes appear to be 1:2 electrolytes. An octahedral geometry is proposed for all the complexes.

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Synthesis Of New 3-Pyrrolin-2-One Derivatives, Nezi̇re Saygili, Ayşegül Altunbaş, Akgül Yeşi̇lada Jan 2006

Synthesis Of New 3-Pyrrolin-2-One Derivatives, Nezi̇re Saygili, Ayşegül Altunbaş, Akgül Yeşi̇lada

Turkish Journal of Chemistry

Six new 3-pyrrolin-2-one derivatives were synthesized via the condensation reaction of amino acid esters (2a-f) with 2,5-dimethoxy-2,5-dihydrofurane (1) in acidic medium. This simple one-pot reaction furnished the corresponding pyrrolinones (3a-f) in acceptable yields.

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Synthesis Of Novel Antimycobacterials And A Fluorescent Sensor For Simple Carbohydrates, Brian Thomas Walker Jan 2006

Synthesis Of Novel Antimycobacterials And A Fluorescent Sensor For Simple Carbohydrates, Brian Thomas Walker

Theses and Dissertations

Cell surface carbohydrates play an important role in a wide variety of biological processes such as inflammation, tumor metastasis, and viral and bacterial infection. The goal of our research has been two-fold. The first objective was the synthesis of antimycobacterial compounds. A mannose containing tetrasaccharide from the mannan core of lipoarabinomannan (LAM) of Mycobacterium tuberculosis has been synthesized using α-D-methylmannopyranoside as starting material and Koeings-Knorr reactions to couple saccharides. The synthesis was completed in nine steps and in 14% total yield. This compound should be useful in competitive inhibition studies with macrophages or as an immunological marker. We have successfully …

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The Synthesis, Characteristics And Performance Of Cnt Composites As Anodic Materials In Litium-Ion Battery, Quan-Feng Dong, Ming-Sen Zheng, Zhen-Cai Huang, Ming-Gang Jin, Ya-Ding Zhan, Zu-Geng Lin May 2005

The Synthesis, Characteristics And Performance Of Cnt Composites As Anodic Materials In Litium-Ion Battery, Quan-Feng Dong, Ming-Sen Zheng, Zhen-Cai Huang, Ming-Gang Jin, Ya-Ding Zhan, Zu-Geng Lin

Journal of Electrochemistry

As an anodic material for lithium ion battery the carbon nano-tube (CNT) and some compounds based on tin have ever been investigated intensively. The fruited progress has not been made yet, however. In this paper the composites of CNT and Sn/SnO2 were synthesized employing two methods and characterized by SEM and XRD. And the electrochemical performance of the composites was investigated.

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The Synthesis Of Biomimetic Tungsten And Molybdenum Complexes, John Sterling Cole Iii May 2005

The Synthesis Of Biomimetic Tungsten And Molybdenum Complexes, John Sterling Cole Iii

Honors Theses

The synthesis of novel biomimetic molybdenum and tungsten compounds that are potential model complexes for molybdenum and tungsten oxidase enzymes is being pursued. Model complexes such as these provide a better understanding of the basic chemistry of a metal center in an environment similar to that found in particular enzyme active sites. This understanding provides a good starting point for biologists or biochemists studying those biological systems. The first target complex will incorporate a tetradentate-S4 ligand (L) that features two biphenyl-S2 fragments joined by a propyl linker. The second target complex will incorporate a bidentate ligand (L') with a singly …

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Synthesis, Characterization And Primary Antimicrobial Activity Evaluation Of 3-Phenyl-6-Methyl-4(3h)-Quinazolinone-2-Yl-Mercaptoacetic Acid Arylidenehydrazides, Aysel Gürsoy, Banu Ünal, Ni̇lgün Karali, Gülten Ötük Jan 2005

Synthesis, Characterization And Primary Antimicrobial Activity Evaluation Of 3-Phenyl-6-Methyl-4(3h)-Quinazolinone-2-Yl-Mercaptoacetic Acid Arylidenehydrazides, Aysel Gürsoy, Banu Ünal, Ni̇lgün Karali, Gülten Ötük

Turkish Journal of Chemistry

3-Phenyl-6-methyl-4(3H)-quinazolinone-2-yl-mercaptoacetic acid hydrazide (3) was reacted with substituted aldehydes in absolute ethanol to obtain a new series, 3-phenyl-6-methyl-4(3H)-quinazolinone- 2-yl-mercaptoacetic acid arylidenehydrazides (4a-q). The structures of 4a-q were elucidated by elemental analyses and from spectrometric (UV, IR, ^1H-NMR, ^{13}C-NMR and EIMS) data. Then 4a-q were evaluated for antibacterial, antifungal and antitubercular activities. No significant activity was observed against the selected microorganisms.

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Synthesis And Isolation Of New Regioisomeric 4-Thiazolidinones And Their Anticonvulsant Activity, Aysel Gürsoy, Nalan Terzi̇oğlu Jan 2005

Synthesis And Isolation Of New Regioisomeric 4-Thiazolidinones And Their Anticonvulsant Activity, Aysel Gürsoy, Nalan Terzi̇oğlu

Turkish Journal of Chemistry

Two regioisomer series, 2-(3-ethyl-4(3H)-quinazolinone-2- ylmercaptoacetylhydrazono)-3-alkyl/3-aryl-5-methyl-4-thiazolidinones (12-21) and 2-arylimino-3-(3-ethyl-4(3H)-quinazolinone-2-ylmercaptoacetylamino)- 5-methyl-4-thiazolidinones (22-26), were synthesized by the cyclization of 1-(3-ethyl-4(3H)-quinazolinone-2-ylmercaptoacetyl)-4-alkyl/aryl thiosemicarbazides (1-11) with ethyl 2-bromopropionate in the presence of anhydrous sodium acetate in anhydrous ethanolic medium. The structures of 12-26 were confirmed by analytical and spectral data (IR, ^1H-NMR and EIMS). Selected members of the thiosemicarbazides and thiazolidinones were subjected to anticonvulsant activity tests by the National Institute of Neurological Disorders and Stroke MD, USA.

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Synthesis Of Mannich Bases Of Some 2,5-Disubstituted 4-Thiazolidinones And Evaluation Of Their Antimicrobial Activities, Handan Altintaş, Öznur Ateş, Seher Bi̇rteksöz, Gülten Ötük, Meltem Uzun, Di̇lek Şanata Jan 2005

Synthesis Of Mannich Bases Of Some 2,5-Disubstituted 4-Thiazolidinones And Evaluation Of Their Antimicrobial Activities, Handan Altintaş, Öznur Ateş, Seher Bi̇rteksöz, Gülten Ötük, Meltem Uzun, Di̇lek Şanata

Turkish Journal of Chemistry

4-Carbethoxymethyl-2-[(\alpha -chloropropionyl/\alpha -bromobutyryl/\alpha-chloro-(\alpha-phenyl)acetyl)amino]thiazoles (2a-c) were synthesized by the reaction of 4-carbethoxymethyl-2-aminothiazole (1) with \alpha-chloropropionyl chloride, \alpha-bromobutyryl bromide and \alpha-chloro-\alpha -phenylacetyl chloride, respectively, which were then refluxed with ammonium thiocyanate to obtain 5-substituted 2-[(4-carbethoxymethylthiazol-2-yl)imino]-4-thiazolidinones (3a-c). 3a-c were stirred with formaldehyde and various secondary amines to gain 15 novel compounds with the structure 5-substituted 5-(N,N-disubstituted aminomethyl)-2-[(4-carbethoxymethylthiazol-2-yl)imino]-4- thiazolidinones (4a-o). The antibacterial activities of the compounds against S. aureus ATCC 6538, S. epidermidis ATCC 12228, E. coli ATCC 8739, K. pneumoniae ATCC 4352, P. aeruginosa ATCC 1539, S. typhi, Sh. flexneri and Pr. mirabilis ATCC 14153 were tested using disk diffusion, while the antifungal …

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Synthesis, Characterizations, And Evaluation Of New Reactive Two-Photon Absorbing Dyes For Two-Photon Excited Fluorescence Imaging Applications, Katherine J. Hales Jan 2005

Synthesis, Characterizations, And Evaluation Of New Reactive Two-Photon Absorbing Dyes For Two-Photon Excited Fluorescence Imaging Applications, Katherine J. Hales

Electronic Theses and Dissertations

Recent, cooperative advances in chemistry, biology, computing, photophysics, optics, and microelectronics have resulted in extraordinary developments in the biological sciences, resulting in the emergence of a novel area termed 'biophotonics'. The integrative and interdisciplinary nature of biophotonics cuts across virtually all disciplines, extending the frontiers of basic cellular, molecular, and biology research through the clinical and pharmaceutical industries. This holds true for the development and application of the novel imaging modality utilizing multiphoton absorption and its extraordinary contribution to recent advances in bioimaging. Intimately involved in the revolution of nonlinear bioimaging has been the development of optical probes for probing …

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The Stereoselective Synthesis Of The Butyrolactone-Bridged [8-5-5] Tricyclic Ring Systems Of (+/-)-Asteriscanolide Via The Titanium-Mediated Hetero-Pauson-Khand Reaction, Mohamed G. Sherriff Jan 2005

The Stereoselective Synthesis Of The Butyrolactone-Bridged [8-5-5] Tricyclic Ring Systems Of (+/-)-Asteriscanolide Via The Titanium-Mediated Hetero-Pauson-Khand Reaction, Mohamed G. Sherriff

LSU Doctoral Dissertations

The stereoselective construction of the tricyclic ring system of asteriscanolide from cyclooctadiene has been achieved. The synthesis involves two main steps; the synthesis of the aldehyde precursor(5)and the titanium-mediated cabocyclization of 5 to make the three rings of 43 stereoselectively.

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Synthesis Of Isomorphous Prototypic [Crfe_2o(Aco)_6(Tep)_3]Cl And [Crfe_2o(Aco)_6(Tmp)_3]Cl As Oxo-Centered Hetero Tri-Nuclear Carboxylate Complexes, Massoud Rafizadeh, Reza Tayebee, Vahid Amani Jan 2005

Synthesis Of Isomorphous Prototypic [Crfe_2o(Aco)_6(Tep)_3]Cl And [Crfe_2o(Aco)_6(Tmp)_3]Cl As Oxo-Centered Hetero Tri-Nuclear Carboxylate Complexes, Massoud Rafizadeh, Reza Tayebee, Vahid Amani

Turkish Journal of Chemistry

[CrFe_2O(AcO)_6(TEP)_3]Cl, (1), and [CrFe_2O(AcO)_6(TMP)_3]Cl, (2), were prepared by replacing 3 water molecules in the [CrFe_2O(AcO)_6(H_2O)_3]Cl complex with triethyl- and trimethyl-phosphates, respectively. FT-IR spectroscopy confirmed an oxo-centered, carboxylate-bridged, heteronuclear triangular structure for the title compounds. M_3O and MO_4 units adopted D_{3h} and D_{4h} local symmetry, respectively, and are surrounded by 6 bridging acetates with C_{2v} local symmetry.

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Synthesis Of Symmetric And Asymmetric Water-Soluble Porphyrin Derivatives, Caroline Owendi Ongayi Jan 2005

Synthesis Of Symmetric And Asymmetric Water-Soluble Porphyrin Derivatives, Caroline Owendi Ongayi

LSU Doctoral Dissertations

Novel symmetric and asymmetric water-soluble tetrabenzoporphyrin are synthesized in relatively good yields. These compounds are synthesized by the condensation of butanopyrrole with several aldehydes that contain masked water solubilizing groups followed by metal insertion, oxidation and demetallation and deprotection of the masked solubilizing groups. The biological evaluation (in vitro and in vivo) studies are described in addition to the photophysical evaluations of the corresponding compounds. A novel versatile route to the syntheses of novel free-bases and metallo-benzoylbiliverdin is discussed. The treatment of metal free-dodecasubstituted porphyrin with sodium nitrite and trifluoroacetic acid at room temperature in the presence of oxygen affords …

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The Synthesis And Characterization Of Bicyclooxacalixarenes, Kevin J. Selby Jan 2005

The Synthesis And Characterization Of Bicyclooxacalixarenes, Kevin J. Selby

Honors Theses

Bicyclooxacalixarenes were synthesized in high yield via a selective, room temperature Sn Ar reaction of phluoroglucinol with 2,6-dichloropyridines. Functionality on the 2,6-dichloropyridioe was varied by changing the electron-withdrawing groups in the 3 and 5 positions (using chlorine, nitro groups, and cyano groups) and the side-chains in the 4-position (using ethyl, butyl, phenyl and ρ-tolyl groups). The resulting cage-like molecules were studied by X-ray crystallography and tested for metal complexation.

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The Syntheses Of Novel Indicators And Materials For Chiral Separation, Rolanda Johnson Jan 2004

The Syntheses Of Novel Indicators And Materials For Chiral Separation, Rolanda Johnson

LSU Doctoral Dissertations

The colorimetric properties of resorcinarene solutions had not been fully investigated since von Baeyer's initial synthesis. We find that the solutions containing resorcinarene macrocycles develop color upon heating or standing. In the presence of saccharides, these solutions exhibit significant color changes which are readily observable by visual inspection. We determined that the solution color is due to macrocycle ring opening and oxidation. The optical responses to saccharides are due to complexation of the sugar with the acyclic chromophores. We have applied these mechanistic insights towards the challenging problems of the visual detection of saccharides and other important biologically analytes. In …

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Synthesis And Antibacterial Assessment Of Water-Soluble Hydrophobic Chitosan Derivatives Bearing Quaternary Ammonium Functionality, Mrunal R. Thatte Jan 2004

Synthesis And Antibacterial Assessment Of Water-Soluble Hydrophobic Chitosan Derivatives Bearing Quaternary Ammonium Functionality, Mrunal R. Thatte

LSU Doctoral Dissertations

Chitosan is a naturally occurring, bio-degradable, non-toxic, non-allergenic bio-polysaccharide derived from chitin, found in abundance in nature. Studies aimed at deriving newer applications of chitosan are hence of interest. Among these, one of the focuses of investigations is aimed at excellent antimicrobial activity demonstrated by chitosan. In this context, certain quaternary ammonium derivatives of chitosan have been shown in the past to be highly effective antibacterial materials. In the present study, substituted chitosan derivatives were synthesized and further quaternized using Quat-188 to produce water soluble derivatives at neutral pH. The antibacterial assessments of the quaternized derivatives of substituted chitosan were …

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Synthesis Of Some New Benzimidazole Carbamate Derivatives For Evaluation Of Antifungal Activity, Canan Kuş, Nurten Altanlar Jan 2003

Synthesis Of Some New Benzimidazole Carbamate Derivatives For Evaluation Of Antifungal Activity, Canan Kuş, Nurten Altanlar

Turkish Journal of Chemistry

The synthesis and structure elucidation of methyl 5(6)-fluoro-6(5)-substituted-1H-benzimidazole carbamate derivatives are performed and their antifungal activities evaluated against Candida albicans.

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Synthesis And Analgesic And Anti-Inflammatory Activity Of New Pyridazinones, Deni̇z S. Doğruer, M. Fethi̇ Şahi̇n, Esra Küpeli̇, Erdem Yeşi̇lada Jan 2003

Synthesis And Analgesic And Anti-Inflammatory Activity Of New Pyridazinones, Deni̇z S. Doğruer, M. Fethi̇ Şahi̇n, Esra Küpeli̇, Erdem Yeşi̇lada

Turkish Journal of Chemistry

A new series of 2-(6-oxo-3,5-diphenyl-6H-pyridazin-1-yl)- acetamides and 3-[6-oxo-3,5-diphenyl-6H-pyridazin-1-yl)-propanamides were synthesized and evaluated in terms of their analgesic and anti-inflammatory activities. All compounds except for 7g were more potent than aspirin in a p-benzoquinone--induced writhing test at 100 mg/kg dose. Compounds 7b, 7c and 7e had the highest anti-inflammatory activity; compound 7e was the most potent in terms of analgesic and anti-inflammatory activities and had no ulcerogenic side effects.

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Possible Cobalt-Cobalt Bridging By A Hemiacetal In The Dinuclear Cobalt Complex Bearing The Ligand Bis(3-(2-Pyridylmethyleneamino)Phenyl) Sulfone, Armando M. Guidote Jr, Tomoko Imajo, Yasuhiko Kurusu, Yoshiro Masuyama Jan 2003

Possible Cobalt-Cobalt Bridging By A Hemiacetal In The Dinuclear Cobalt Complex Bearing The Ligand Bis(3-(2-Pyridylmethyleneamino)Phenyl) Sulfone, Armando M. Guidote Jr, Tomoko Imajo, Yasuhiko Kurusu, Yoshiro Masuyama

Chemistry Faculty Publications

A dinuclear cobalt complex bearing the ligand bis(3-(2-pyridylmethyleneamino)phenyl) sulfone (BPMAPS) was prepared. It is proposed that the structure of this is [Coz(BPMAPS)(m-0AcMhemi-Et)]PF6 wherein the cobalt centers are bridged by two carboxylato groups in m-fashion and a hemiacetal with an ethoxy group (hemi-Et). This proposal is based on the similarity of the FT-IR, UV-Vis, and FAB-MS results with the crystallographically characterized dinuclear manganese complex [Mn2(BPMAPS)(m-OAcMhemi-Me)]PF6, and elemental analysis results.

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Synthesis And Antimicrobial Testing Of Some Flavonylsulfonamide Derivatives, Gülgün Ayhan Kilcigi̇l, Oya Bozdağ Dündar, Rahmi̇ye Ertan, Nurten Altanlar Jan 2003

Synthesis And Antimicrobial Testing Of Some Flavonylsulfonamide Derivatives, Gülgün Ayhan Kilcigi̇l, Oya Bozdağ Dündar, Rahmi̇ye Ertan, Nurten Altanlar

Turkish Journal of Chemistry

Six new 4-amino-N-heteroaryl,N-[(2-phenyl-4H-1-benzopyran-4- oxo-6-yl)metil]benzensulfonamide derivatives, (3a-3f) were prepared by reacting 6-bromomethylflavone with the corresponding sulfonamide derivatives and their antimicrobial activities against Escherichia coli were evaluated. All of the compounds exhibited better activity (except compound 3c) than the corresponding sulfonamide derivatives.

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Synthesis, Characterization And Primary Antituberculosis Activity Evaluation Of 4-(3-Coumarinyl)-3-Benzyl-4-Thiazolin-2-One Benzylidenehydrazones, Aysel Gürsoy, Ni̇lgün Karali̇ Jan 2003

Synthesis, Characterization And Primary Antituberculosis Activity Evaluation Of 4-(3-Coumarinyl)-3-Benzyl-4-Thiazolin-2-One Benzylidenehydrazones, Aysel Gürsoy, Ni̇lgün Karali̇

Turkish Journal of Chemistry

In this study a new series of 4-(3-coumarinyl)-3-benzyl-4-thiazolin- 2-one benzylidenehydrazones 3a-t was synthesized. Structures of the title compounds were elucidated by elemental analyses and spectrometric data (IR, ^1H-NMR, ^{13}C-NMR and EIMS). 3a-t were evaluated for antituberculosis activity against Mycobacterium tuberculosis} H37Rv in BACTEC 12B medium using the BACTEC 460 radiometric system.

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Synthesis Of Montiporynes A And B, Traci Jenelle Speed Jan 2003

Synthesis Of Montiporynes A And B, Traci Jenelle Speed

Honors Theses

This thesis reports the first complete synthesis of monriporynes A and B. isomeric diacetylenes that bear α, β unsaturated ketone functionalities. Recently isolated from the stony coral Montipora sp. these compounds are reported to possess in vitro cytotoxic activity against several human solid tumor cells. We have synthesized both isomers in three simple steps. In the first step, l-iodononyne was prepared by reacting 1-nonyne with N-iodosuccinimide and a catalytic amount of silver nitrate. This iodoalkyne was then coupled with propargyl alcohol using copper iodide as the catalyst to give 2,4dodecadiynyl alcohol. Finally, the diacetylenic alcohol was subjected to the Swern …

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Synthesis Of New Substituted 6-(Morpholin-4-Yl)-1h-Benzimidazole Derivatives, Canan Kuş Jan 2002

Synthesis Of New Substituted 6-(Morpholin-4-Yl)-1h-Benzimidazole Derivatives, Canan Kuş

Turkish Journal of Chemistry

A series of various substituted benzimidazole derivatives containing fluoro and morpholino substituents at the 5 and 6 positions was synthesized and their structures were identified by spectroscopic techniques.

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The Synthesis Of Bromoethoxy And Vinylbenzyloxy Substituted Nlo Chromophores, Michael Joseph Matuszewski Jan 2002

The Synthesis Of Bromoethoxy And Vinylbenzyloxy Substituted Nlo Chromophores, Michael Joseph Matuszewski

Browse all Theses and Dissertations

Multiphoton-absorption processes have recently attracted growing interest because of the potential impact on a wide spectrum of applications, ranging from data storage to photodynamic therapy. From the materials standpoint, particular interest is centered in designing chromophores that exhibit a large two-photon cross-section. The current research is focused on establishing synthetic routes that lead to the formation of derivatives of N,N-diphenyl-(7-benzothiazol-2-yl)-9,9-diethyl-9H-fluoren-2-ylamine which contain meta functionalization. A bromoethoxy functionalized chromophore, N-phenyl-N-(3-(2-bromoethoxy)phenyl)-7-(benzothiazol-2-yl)-9,9-diethyl-9H-fluoren- 2-ylamine , was synthesized and used as a polymer pendent while a vinylbenzyloxy chromophore, N-phenyl-N-(3-(4-vinylbenzyloxy)phenyl)-7- (benzothiazol-2-yl)-9,9-diethyl-9H-fluoren-2-ylamine, was synthesized as a hydrosilation substrate. A compound containing three chromophores, 1,3,5-tris(3-(N-phenyl- 4-(7-(benzothiazol-2-yl)-9,9-diethyl-9H-fluoren-2- ylanilino)phenoxymethyl)benzene, has …

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