Chemistry Commons^™

Characterization By Nmr Of Reactants And Products Of Hydrofluoroether Isomers, Cf3(Cf2)3och3 And (Cf3)2c(F)Cf2och3, Reacting With Isopropyl Alcohol, Howard Knachel, Vladimir Benin, William E. Moddeman, Janine C. Birkbeck, Thomas A. Kestner, Tayna L. Young

Chemistry Faculty Publications

The 3M Company product Novec™ 71IPA DL, a mixture of methoxyperfluorobutane, methoxyperfluoroisobutane and 4.5 wt.% isopropyl alcohol, has been found to be very stable at ambient temperature, producing fluoride at the rate of ~1 ppm/year. Our earlier kinetic and theoretical studies have identified the reaction mechanism. This paper identifies the ¹H and ¹⁹F NMR chemical shifts, multiplicities, and coupling constants of reactants and the major products that result from aging the mixture in sealed Pyrex NMR tubes for periods up to 1.8 years at temperatures from 26 °C to 102 °C. Chemical shifts and coupling constants of fluorine …

Redesigned Storm Water Management System For The Portage Lakefront, Nicholas Adams, Agustin Perez Maldonado

Symposium on Research and Creative Expression (SORCE)

The work described here was carried out at the Indiana Dunes National Lakeshore, located near Gary, Indiana. The goal of the reported project was to fix an incorrectly designed storm water management system located at the Portage lakefront. Because the original design could not handle peak water flows, there has been erosion of the sand dunes. The erosion of the sand dunes has led to the collapsing of stairs, and the exposure of water mains. To fix these problems, a new design was made that incorporated additional water inlets, as well as a pipeline to take water to a different …

Cyclization Reactions Of Enamines In Aqueous Solution, Jack Albert

Symposium on Research and Creative Expression (SORCE)

Enamines are organic molecules with a nitrogen atom adjacent to a carbon-carbon double bond formed by a reaction between an aldehyde/ketone and a secondary amine. It has previously been found that when a secondary amine with a nucleophilic side chain is reacted with an aldehyde/ketone, instead of forming an enamine, a cyclization reaction occurs. These reactions are carried out in organic solvents such as benzene or toluene. The current study is an attempt to create a green synthesis of these species, by studying reactions of 2-piperidinemethanol with various aldehydes/ketones in water (Figure 1) and reactions of 2-piperidineethanol with various aldehydes/ketones …

Characterization Of The Gas-Sensing Protein Cooa, Teryn Gehred, Jessica Lyza

Symposium on Research and Creative Expression (SORCE)

This research aims to characterize the binding specificity of heme proteins to various gas signal molecules. Heme proteins in the gas-sensing family bind to specific gas signal molecules, causing a certain biological function to be activated or deactivated. In this study, variants of the carbon monoxide sensing heme protein CooA from the bacteria R.rubrum and C. hydrogenoformans are compared. Key differences in signal binding specificity and heme environment configuration will be investigated. This is done by using site-directed mutagenesis to alter the heme environment, isolating the CooA proteins through protein purification, and analyzing the isolated products through DNA binding assays. …

A Theoretical Study Of Brooker's Merocyanine With (2-Hydroxypropyl)-Β-Cyclodextrin, Benjamin Helmsing

Symposium on Research and Creative Expression (SORCE)

To understand the important forces in host-guest complexes, a theoretical study of these systems was carried out using computational methods to better understand experimental results. β-cyclodextrin (BCD) is a cone shaped molecule where the narrow end is known as the primary rim and the wider end is known as the secondary rim. The host molecule being studied, (2-hydroxypropyl)-β-cyclodextrin (2HPBCD),is a modified version of BCD with hydroxypropyl (HP) groups substituted along the rims. Because this modification replaces some of the OH groups present in BCD, it removes their ability to hydrogen bond, while introducing new OH groups that are more flexible. …

Synthesis Of An Epoxide For Tmm Cycloadditions, Will Prusinski, Chase Freeland

Symposium on Research and Creative Expression (SORCE)

In order to produce a highly functionalized five-membered ring useful for further synthetic processes via Palladium catalysis, a series of precursors need to be synthesized in order to form the epoxide used in cyclic formation. First, a trimethylsilane alcohol is synthesized from beta-Methallyl alcohol. The alcohol will then be subjected to Swern oxidation conditions, forming a TMS aldehyde. The aldehyde prepared will then undergo epoxidation, forming the desired precursor for Palladium catalyzed cycloaddition. The Swern oxidation has yet to occur in good conversion due to sensitivity, but when performed using a model compound the oxidation, and epoxidation both worked to …

Study Of Ligand Binding Reactions Of Bis-Aminemetalloporphyrins, Frank Wang

Symposium on Research and Creative Expression (SORCE)

Porphyrins are molecular complexes that are critical for the proper functioning of many important biological macromolecules such as hemoglobin and myoglobin. The goal of this research is to monitor the transformations and differences that occur with the addition of metals and ligands to a model porphyrin compound called tetraphenylporphyrin (TPP). During this work, a series of metalloporphyrin complexes were prepared, with changes to both metal centers and ligand attachments at those centers. Specifically, iron, zinc, cobalt and manganese metalloporphyrins have been synthesized and identities verified via electronic absorption spectroscopy. Ligand binding studies have begun with the addition of piperidine and …

Cristal (Chemistry Resources And Instructional Strategies For Teaching All Learners For Ms & Hs Chemistry), Jody Stone

K-12 Curriculum Supplements

The CRISTAL program was developed for the purpose of (1) increasing the number of quality laboratory experiences carried out in high school chemistry classes (2) providing learning activities designed to stimulate the development of reasoning/problem-solving skills and (3) providing chemistry teachers with ideas and strategies for creating a more student-centered classroom. The intended audience is all students enrolled in high school chemistry, especially those students needing additional motivation for learning chemistry.

The CRISTAL materials include a teacher's resource manual containing over 100 activities. These laboratories are arranged in a learning cycle format involving exploratory and application activities. One or more …

Inverse Versus Normal Dithienylethenes: Computational Investigation Of The Photocyclization Reaction, AuréLie Perrier, StéPhane Aloise, Massimo Olivucci, Denis Jacquemin

Chemistry Faculty Publications

The understanding of the intimate electronic processes in photochromes is essential to optimize the properties of light-controllable devices. For one of the most studied classes of molecular switches, namely, dithienylethenes, the relative efficiencies of the normal and inverse structures remained puzzling. Indeed, despite a larger ratio of the active antiparallel conformers for the latter, the quantum yields of cyclization of inverse dithienylethenes do not exceed those of its normal counterpart. In the present contribution, we provide the first explanation of this experimental outcome using multireference ab initio quantum chemistry. We demonstrate the existence of a fluorescent intermediate on the S-1 …

A, Catalysis Of Co-Prox By Water-Soluble Rhodium Fluorinated Porphyrins. B, Studies Toward Fluorination Of Electron Rich Aromatics By Nucleophilic Fluoride, Shri Harsha Uppaluri

Department of Chemistry: Dissertations, Theses, and Student Research

The rhodium(III) derivative of a water soluble, heavily fluorinated porphyrin is shown to catalyze the low temperature, low pressure selective oxidation of carbon monoxide in hydrogen gas streams for use in fuel cell applications. The catalytic activity is a direct result of the removal of electron density from the metal center. Selectivity for CO oxidation is a direct consequence of fluorination of the porphyrin periphery, since these substituents enhance the rate of the reaction and prevent the formation of Rh(II)-Rh(II) dimmers. Significantly, the dramatic increase in rhodium hydride acidity caused by fluorination precludes hydrogen activation and generation, thereby permitting preferential …

Coupling Fast Water Exchange To Slow Molecular Tumbling In Gd3+ Chelates: Why Faster Is Not Always Better, Stefano Avedano, Mauro Botta, Julian Saunders Haigh, Dario L. Lango, Mark Woods

Chemistry Faculty Publications and Presentations

The influence of dynamics on solution state structure is a widely overlooked consideration in chemistry. Variations in Gd³⁺ chelate hydration with changing coordination geometry and dissociative water exchange kinetics substantially impact the effectiveness (or relaxivity) of monohydrated Gd³⁺ chelates as T1-shortening contrast agents for MRI. Theory shows that relaxivity is highly dependent upon the Gd³⁺–water proton distance (rGdH), and yet this distance is almost never considered as a variable in assessing the relaxivity of a Gd³⁺ chelate as a potential contrast agent. The consequence of this omission can be seen when considering …

Preparation Of A Semiquinonate-Bridged Diiron(Ii) Complex And Elucidation Of Its Geometric And Electronic Structures, Amanda E. Baum, Sergey V. Lindeman, Adam T. Fiedler

Chemistry Faculty Research and Publications

The synthesis and crystal structure of a diiron(II) complex containing a bridging semiquinonate radical are presented. The unique electronic structure of this S = 7/2 complex is examined with spectroscopic (absorption, EPR, resonance Raman) and computational methods.

Analisis Variasi Genetik Varian Jati Arboretum Dengan Penanda Mikrosatelit, Imas Cintamulya

Jurnal Pendidikan Sains

Seleksi tanaman jati untuk memperoleh sifat unggul tidak cukup hanya melalui penanda morfologi, tetapi juga perlu menggunakan penanda molekuler berdasarkan polimorfisme DNA. Oleh karena itu, perlu dilakukan kajian tanaman jati dari segi genetik pada level DNA untuk melihat variasi genetik. Informasi tentang variasi genetik jati diperlukan dalam pengadaan bibit untuk pembangunan hutan tanaman industri, dengan tujuan mencegah inbreeding dan mendukung upaya konservasi. Penelitian ini bertujuan untuk menganalisis variasi genetik varian jati arboretum menggunakan penanda molekuler mikrosatelit serta menyusun buku pengayaan kajian dasar-dasar molekuler tumbuhan, khususnya penanda mikrosatelit, dalam menganalisis variasi genetik varian jati arboretum yang berkualitas. Langkah-langkah penelitian meliputi isolasi …

Pembelajaran Kooperatif Tai Dan Game Puzzle Dalam Meningkatkan Motivasi Belajar Dan Pemahaman Konsep Matematika, Any Herawati

Jurnal Pendidikan Sains

Penelitian ini mendeskripsikan rancangan dan pelaksanaan pembelajaran kooperatif Team Assisted Individualized (TAI) dan game puzzle dalam meningkatkan motivasi belajar serta pemahaman konsep fungsi komposisi dan fungsi invers di SMA Negeri 3 Malang. Penelitian ini merupakan penelitian tindakan kelas dengan pendekatan mix research, yang dilaksanakan dalam tiga siklus. Subjek penelitian adalah siswa kelas XI IPA 1 semester genap tahun pelajaran 2011/2012 sebanyak 33 siswa, terdiri atas 13 siswa laki-laki dan 20 siswa perempuan. Data yang dikumpulkan meliputi motivasi belajar dan pemahaman konsep matematika siswa. Hasil penelitian menunjukkan bahwa pembelajaran kooperatif TAI dan game puzzle mampu meningkatkan motivasi belajar dan pemahaman konsep. …

Penggunaan Pita Melalui Pembelajaran Missouri Mathematics Project Untuk Memahamkan Siswa Tentang Luas Permukaan Bola, Pentri Arfia Dewi

Jurnal Pendidikan Sains

Penelitian ini akan mendeskripsikan penggunaan pita melalui pembelajaran Missouri Mathematics Project untuk memahamkan siswa tentang luas permukaan bola. Pembelajaran yang dilaksanakan berdasarkan pada tahapan pembelajaran Missouri Mathematics Project yang dipadukan dengan bahan manipulatif. Penelitian ini merupakan penelitian tindakan kelas. Setiap siklus terdiri dari tiga kali pertemuan. Dalam penelitian ini juga dilakukan kajian dari jawaban siswa. Hasil penelitian ini menunjukkan bahwa penerapan pembelajaran menggunakan bahan manipulatif bola dan pita dapat memahamkan siswa tentang luas permukaan bola.

Persepsi Pengelola Terhadap Peran Sistem Informasi Manajemen (Sim) Berbasis Teknologi Informasi (Ti) Dalam Pengelolaan Administrasi Sekolah Menengah Kejuruan Kota Mojokerto, Tri Wahjoedi Hidajat

Jurnal Pendidikan Sains

Peran sistem informasi manajemen (SIM) berbasis teknologi informasi sangat penting dalam pengelolaan sekolah untuk meningkatkan kualitas pelayanan, proses, dan prestasi belajar siswa. Oleh karena itu, penelitian ini bertujuan untuk mengungkap dan mendeskripsikan persepsi pengelola terhadap peran SIM berbasis TI dalam pengelolaan administrasi SMK di Kota Mojokerto. Penelitian ini menggunakan rancangan deskriptif kuantitatif dan dilaksanakan pada sembilan SMK di Kota Mojokerto dengan 45 pengelola administrasi akademik sebagai populasi. Teknik pengambilan sampel yang digunakan adalah sampel jenuh, yaitu seluruh populasi dijadikan sampel. Hasil penelitian menunjukkan bahwa: (1) secara umum, persepsi pengelola terhadap peran SIM berbasis TI dalam pengelolaan administrasi SMK tergolong penting, …

Integrasi Pendidikan Karakter Melalui Inkuiri Dengan Lesson Study Dalam Pembelajaran Biologi Untuk Meningkatkan Sikap Ilmiah Dan Hasil Belajar Kognitif Siswa Kelas Vii Smpn I Singosari, Elly Lailatul Budur

Jurnal Pendidikan Sains

Pembelajaran inkuiri memungkinkan siswa terlibat secara aktif dalam proses berpikir dan menemukan konsep yang dipelajarinya. Pengetahuan dan keterampilan yang diperoleh siswa diharapkan bukan sekadar hasil menghafal fakta, melainkan hasil dari proses penemuan secara mandiri. Hasil pengamatan awal menunjukkan bahwa siswa SMP Negeri 1 Singosari masih cenderung menghafal materi pembelajaran sehingga keterampilan proses dan sikap ilmiah belum berkembang secara optimal. Selain itu, karakter siswa sebagaimana diamanatkan dalam tujuan pendidikan nasional belum sepenuhnya tercapai. Penelitian ini bertujuan untuk meningkatkan sikap ilmiah dan hasil belajar kognitif siswa melalui integrasi pendidikan karakter dengan metode inkuiri terbimbing berbasis lesson study pada siswa kelas VII SMP …

Pengaruh Model Siklus Belajar Berbantuan Mind Map Terhadap Prestasi Belajar Fisika Ditinjau Dari Kinerja Laboratorium Siswa Kelas Viii Smpn 1 Rejoso Kabupaten Pasuruan, Ary Analisa Rahma

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk menguji pengaruh model siklus belajar berbantuan mind map terhadap prestasi belajar fisika ditinjau dari kinerja laboratorium siswa kelas VIII pada materi cahaya di SMP Negeri 1 Rejoso, Kabupaten Pasuruan. Penelitian ini merupakan penelitian eksperimen semu dengan rancangan faktorial 2 × 2. Subjek penelitian berjumlah 204 siswa. Instrumen penelitian terdiri atas instrumen perlakuan yang meliputi silabus, RPP, dan LKS, serta instrumen pengukuran berupa instrumen kinerja laboratorium dan tes prestasi belajar fisika. Hasil penelitian menunjukkan bahwa prestasi belajar fisika siswa yang belajar menggunakan model siklus belajar berbantuan mind map lebih tinggi dibandingkan dengan siswa yang belajar melalui pembelajaran …

Penerapan Pembelajaran Inkuiri Terbimbing Berbasis Laboratorium Untuk Meningkatkan Keterampilan Proses Dan Hasil Belajar Ipa Siswa Kelas Viii-4 Di Smpn 1 Probolinggo, Karyatin Karyatin

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk mendeskripsikan keterlaksanaan pembelajaran inkuiri terbimbing berbasis kegiatan laboratorium dalam meningkatkan keterampilan proses sains dan hasil belajar kognitif IPA (biologi) siswa. Deskripsi keterlaksanaan pembelajaran diperoleh melalui identifikasi permasalahan yang muncul selama proses pembelajaran di kelas, yang selanjutnya dianalisis untuk menemukan solusi berdasarkan data empiris di lapangan. Penelitian ini juga berupaya mengungkap permasalahan pembelajaran secara menyeluruh dan kontekstual dengan menempatkan peneliti sebagai instrumen kunci. Pendekatan yang digunakan adalah kualitatif dengan jenis penelitian tindakan kelas (PTK) yang dilaksanakan dalam dua siklus. Setiap siklus terdiri atas empat pertemuan dengan alokasi waktu 2 × 40 menit per pertemuan. Teknik pengumpulan data …

Kajian Morfologi, Anatomi, Dan Agronomi Antara Kedelai Sehat Dengan Kedelai Terserang Cowpea Mild Mottle Virus Serta Pemanfaatannya Sebagai Bahan Ajar Di Sekolah Menengah Kejuruan, As’Ad Syamsul Arifin

Jurnal Pendidikan Sains

Salah satu penyebab rendahnya produktivitas kedelai di Indonesia adalah serangan virus belang samar kacang tunggak, Cowpea mild mottle virus (CPMMV). Penelitian ini merupakan penelitian survei yang bertujuan untuk menggambarkan dan mengumpulkan informasi mengenai kajian morfologi, anatomi, dan agronomi terhadap infeksi CPMMV pada varietas yang terinfeksi dan yang tidak terinfeksi. Data dianalisis secara deskriptif dan inferensial menggunakan ANAVA melalui program SPSS for Windows versi 16. Hasil penelitian menunjukkan bahwa varietas Gumitir sehat, Anjosmoro sehat, Mahameru sehat, MLGG 0021, dan MLGG 0268 memiliki ukuran daun, panjang petiol, serta nisbah daun (L/W dan L/PL) lebih besar dibandingkan varietas yang sakit. Varietas Argopuro sakit …

Pembelajaran Berbantuan Multimedia Berdasarkan Teori Beban Kognitif Untuk Meningkatkan Kemampuan Menyelesaikan Masalah Program Linear Siswa X Tkr 1 Smkn 1 Doko, Fifi Damayanti

Jurnal Pendidikan Sains

Berdasarkan teori beban kognitif, pembelajaran efektif terjadi apabila beban intrinsic dikelola dengan baik, beban germane ditingkatkan, dan beban extraneous dikurangi. Penerapan multimedia merupakan salah satu upaya untuk mencapai pembelajaran yang efektif. Penelitian ini mengkaji penerapan pembelajaran matematika berbantuan multimedia dalam meningkatkan kemampuan siswa menyelesaikan masalah program linear. Penelitian ini menggunakan pendekatan penelitian tindakan kelas yang dilaksanakan dalam dua siklus. Hasil penelitian menunjukkan bahwa penggunaan multimedia dapat mengelola beban intrinsic, meningkatkan beban germane, dan mengurangi beban extraneous, sehingga kemampuan siswa dalam menyelesaikan masalah program linear meningkat.

Pengembangan Profesionalitas Berkelanjutan/Continuing Professional Development (Cpd) Guru Bersertifikat Pendidik Di Smk Rumpun Teknologi Se-Malang Raya, Sujianto Sujianto

Jurnal Pendidikan Sains

Penelitian ini bertujuan untuk mendeskripsikan pengembangan profesionalitas berkelanjutan guru bersertifikat pendidik melalui investasi pengembangan diri, publikasi ilmiah, dan karya inovatif, baik secara mandiri, berkelompok, maupun melembaga. Penelitian menggunakan rancangan deskriptif kuantitatif dengan subjek guru kejuruan bersertifikat pendidik di wilayah Malang Raya. Instrumen penelitian meliputi kuesioner (angket) dan pedoman wawancara. Hasil penelitian menunjukkan bahwa pemberlakuan Undang-Undang Guru dan Dosen (UU Nomor 14 Tahun 2005) yang disertai pemberian tunjangan profesi sejatinya memberikan harapan besar dalam mendorong minat guru untuk terus mengembangkan profesionalitasnya. Namun, temuan penelitian menunjukkan kondisi yang berbeda. Tingkat pengembangan profesionalitas berkelanjutan guru bersertifikat pendidik di SMK rumpun teknologi se-Malang Raya …

Effect Of Ethyl Propionate On Low-Temperature Performance Of Lifepo4-Based Li-Ion Battery, Xiao-Ping Li, Lian-Sheng Hao, Wei-Shan Li, Meng-Qing Xu, Li-Dan Xing

Journal of Electrochemistry

A linear carboxylic, ester ethyl propionate (EP), was used as the co-solvent of carbonates, ethylene carbonate (EC), ethyl-methyl carbonate (EMC) and dimethyl carbonate (DMC), and its effect on low-temperature performance of LiFePO₄-based Li-ion battery was studied by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and galvanostatic charge-discharge test. The application of EP enhances the ionic conductivity of the electrolyte, improves the compatibility of the electrolyte with both LiFePO₄ and graphite materials, and thus improves the low-temperature performance of LiFePO₄-based Li-ion battery. The Li-ion battery using the optimized electrolyte of 1 mol·L^-1 LiPF₆/EC:EMC:DMC:EP …

Multifunctional Corrosion Inhibition Behavior Of Zn-Al Calcined Layered Double Hydroxides For Steel Rebar In Nacl Solution, Xiao-Juan Zhang, Jing-Jing Wang, Shi-Gang Dong, Chang-Jian Lin

Journal of Electrochemistry

The Zn-Al layered double hydroxides (Zn-Al LDHs) and calcined products (Zn-Al CLDHs) were synthesized successfully under a routine air atmosphere. The results showed that both Zn-Al LDHs and Zn-Al CLDHs had obvious flake structures. The corrosion inhibition of Zn-Al CLDHs for steel rebar in NaCl solution was studied by electrochemical techniques. It was found that the corrosion rate of steel rebar decreased significantly after the steel rebar was treated by Zn-Al CLDHs in NaCl solution for 3 h. It was indicated that Zn-Al CLDHs could absorb Cl^- and release OH^- during their reconstruction process, which provided dual protection …

Influences Of The Cinnamic Acid On Zinc Electrodeposition At Glassy-Carbon Electrode, Kai Li, Shen Chen, Shen-Na Liu, Bi-Sang Chen, Heng Lin, Guo-Liang Chen, Qing-Xiang Wang

Journal of Electrochemistry

The influences of cinnamic acid (CIN) on the mechanism of Zn deposition and nucleation kinetics onto glassy-carbon electrode were studied by cyclic voltammetry (CV) and chronoamperometry (CA). The results revealed that the zinc reduction took place via Zn²⁺ + 2e → Zn in the presence of CIN, but the kinetics of zinc deposition was changed and the formation rate of zinc nuclei was accelerated. In the absence of CIN, the mechanism of zinc nucleation followed the 3D-instantaneous diffusion-controlled nucleation, while the 3D-progressive diffusion-controlled nucleation in the presence of CIN. The addition of CIN reduced the nucleation rate, but increased …

Preparation And Characterization Of A Novel Composite Electrolyte Ceria-Sulfate For Intermediate Temperature Solid Oxide Fuel Cells, Ze Tong, Yi-Mei Yin, Jie-Wei Yin, Zi-Feng Ma

Journal of Electrochemistry

A novel composite electrolyte SDC-(Li/Na)₂SO₄ was prepared for intermediate temperature solid oxide fuel cells (ITSOFC). The phase structure and cross-sectional morphology were examined by XRD and SEM, respectively, and the ionic conductivity was investigated by AC impedance in a temperature range of 400 ^oC ~ 700 ^oC in air. It was found that the composite electrolyte was composed of two phases: crystal SDC and amorphous (Li/Na)₂SO₄. The conductivity of the composite electrolyte was significantly larger than that of SDC at intermediate temperatures (550 ^oC ~ 700 ^oC) and increased …

The Effect Of Precursors On Performance Of Lini0.5Co0.2Mn0.3O2 Cathode Material, Dong-Ge Hu, Zhang-Zhi Wang, Jia-Li Liu, Tao Huang, Ai-Shui Yu

Journal of Electrochemistry

Commercial LiNi_0.5Co_0.2Mn_0.3O₂ material is generally prepared by a combination of co-precipitation and solid state reaction method. The particle size distribution and morphology of Ni_0.5Co_0.2Mn_0.3(OH)₂ precursor have a great impact on the electrochemical performance of LiNi_0.5Co_0.2Mn_0.3O₂. In this work, the crystal structure and surface morphology of LiNi_0.5Co_0.2Mn_0.3O₂ prepared by three different precursors were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). Particle size distribution, tap density and electrochemical performance were …

Carcinogenic Adducts Induce Distinct Dna Polymerase Binding Orientations, Kyle B. Vrtis, Radoslaw P. Markiewicz, Louis J. Romano, David Rueda

Chemistry Faculty Research Publications

DNA polymerases must accurately replicate DNA to maintain genome integrity. Carcinogenic adducts, such as 2-aminofluorene (AF) and N-acetyl-2-aminofluorene (AAF), covalently bind DNA bases and promote mutagenesis near the adduct site. The mechanism by which carcinogenic adducts inhibit DNA synthesis and cause mutagenesis remains unclear. Here, we measure interactions between a DNA polymerase and carcinogenic DNA adducts in real-time by single-molecule fluorescence. We find the degree to which an adduct affects polymerase binding to the DNA depends on the adduct location with respect to the primer terminus, the adduct structure and the nucleotides present in the solution. Not only do the …

Preparation And Electrochemical Performance Of Hollow Carbon Spheres/Sulfur Composite, Jun Zang, Hang Qian, Er-Man Zeng, Juan-Ni Fu, Ming-Sen Zheng, Quan-Feng Dong

Journal of Electrochemistry

Hollow carbon spheres were prepared by the PMMA template. Hollow carbon spheres/sulfur composite was made from sulfur and hollow carbon spheres as a conducting framework. The results of SEM and TEM showed that sulfur was uniformly filled in both of the shell and hollow core of hollow carbon spheres. The electrochemical performance of hollow carbon spheres/sulfur composite was characterized by the charge/discharge method. The results showed the excellent rate and cycle performance of hollow carbon spheres/sulfur composite. The reversible capacities of hollow carbon spheres/sulfur composite are 1145 mAh·g^-1, 824 mAh·g^-1, 702 mAh·g^-1, 586 mAh·g …

Polypyrrole-Transition Metal-Oxygen Coordination Complexes As High Performance Lithium Storage Material, Ya Mao, Qingyu Kong, Bingkun Guo, Zhaoxiang Wang, Liquan Chen

Journal of Electrochemistry

No abstract provided.